Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.1.8 (
cholinesterase
)
12,691
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Two men were accidentally exposed to vapors of sarin, a
cholinesterase
inhibitor and extremely toxic nerve gas. Diagnosis was confirmed by depressed
cholinesterase
activity, and fixed extremely miotic pupils. No other signs or symptoms developed and neither man required treatment. Recovery to normal
cholinesterase
activity was gradual over a 90-day period. Pupillary reflexes were not detectable until 11 days after exposure; the miotic pupils dilated slowly over a 30-45 day-period.
Eye pain
and blurred vision did not occur; visual acuity and amplitude of accommodation were improved for several weeks. Other functions not affected significantly were intraocular pressure, visual fields, color vision, heterophorias, and vergences.
...
PMID:Accidental exposure to sarin: vision effects. 397 1
