Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.1.8 (cholinesterase)
 12,691 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Anterior abdominal wall defects, omphalocele and gastroschisis are rare fetal anomalies. Prenatal diagnosis of these conditions has improved with the widespread use of ultrasound and serum alpha-fetoprotein and amniotic fluid cholinesterase levels. Improvements in prenatal diagnosis have allowed appropriate and timely intensive care and surgical intervention, reducing morbidity and mortality. As more of these infants survive, gynecologists will more frequently encounter them as adults with a condition requiring surgical correction. Two cases demonstrate that well-planned surgery can maximize the outcome for these patients.
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PMID:Gynecologic surgery after repair of gastroschisis or omphalocele. A report of two cases. 183 2

To determine the pathomechanism of the condition of CF 1 mutant mice which present paralytic club feet, anatomicohistological analysis (conventional histological staining, silver impregnation, cholinesterase staining, and retrograde tracer technique of horseradish peroxidase (HRP)) were carried out. CF 1 homozygotic mutant mice lacked the common peroneal nerve, while tibial nerve is larger than that of normal mice when they were compared at the similar levels of the posterior limbs. Anterior and lateral crural muscles of the homozygotic mutant mice except for peroneus longus and brevis muscles showed large group muscle atrophy. HRP study indicated that the number of HRP labeled cells after injection of HRP into the anterior and lateral crural muscles decreased remarkably in number in the homozygotic mutant mice, comparing with that of the normal mice.
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PMID:A morphological analysis of a new mutant mice with paralytic club feet, peroneal muscular atrophy (pma). 667 99