Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.1.8 (
cholinesterase
)
12,691
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Dichlorvos (DDVP) is used as an antihelmetic, principally in dogs, cats, pigs and horses.
Retina
, whole blood, erythrocyte, plasma and brain
cholinesterase
(ChE) activities were monitored following DDVP exposure in cats to establish their use as indicators of exposure to a ChE inhibitor. Following DDVP exposure, whole blood ChE activity was 16.8% of preexposure, erythrocyte ChE activity was 33% of preexposure, and plasma ChE was 19% of preexposure values. Brain and retinal ChE activities were reduced to 45% and 43% of control values. Retinal ChE paralleled brain activity.
...
PMID:Retina, brain and blood cholinesterase levels in cats treated with oral dichlorvos. 835 88