Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.1.79 (
hormone-sensitive lipase
)
2,163
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
hormone-sensitive lipase
2163
insulin
384
adipose triglyceride lipase
303
Pseudomonas
283
lipase
219
lipoprotein lipase
205
perilipin
185
Mol
175
Sep
146
fatty acid synthase
125
peroxisome proliferator-activated receptor
109
leptin
108
epididymal
88
adiponectin
71
AMP
69
C10
68
AMP-activated protein kinase
65
FAS
63
acetyl-CoA carboxylase
61
peroxisome proliferator-activated receptor gamma
59
esterase
56
LPL
56
uncoupling protein 1
54
ATP
48
CD36
46
PKA
46
Hormone-sensitive lipase
45
AMPK
44
tumor necrosis factor
39
aP2
34
PPAR
33
cAMP-dependent protein kinase
32
DCS
32
phosphodiesterase
31
transcriptional regulator
31
adipokine
30
TNF
30
monoacylglycerol lipase
30
GLUT4
30
sterol regulatory element-binding protein
29
glucose transporter
29
CPT
29
cytokine
28
HDL
28
glucagon
27
IL-6
27
growth hormone
26
FABP4
26
SREBP-1c
26
insulin receptor
26
transcriptional activator
25
carnitine palmitoyltransferase
24
PGC
24
UCP2
24
endoplasmic reticulum
23
IRS-1
23
adenylate cyclase
22
CPT1
21
ACC
21
ERK1
21
SREBP-1
20
diacylglycerol acyltransferase
19
fatty acid binding protein
19
cholesterol esterase
19
carnitine palmitoyltransferase 1
19
AKT
18
hepatic lipase
18
ERK
18
UCP3
18
adenylyl cyclase
16
extracellular signal-regulated kinase
16
lipopolysaccharide
16
Leptin
16
MAPK
16
phosphoenolpyruvate carboxykinase
16
carboxylesterase
16
polypeptide
15
SCD1
15
glycerol-3-phosphate dehydrogenase
15
NEFA
15
more...
Disease
obesity
316
diabetes
88
FAS
63
type 2 diabetes
51
fatty liver
39
cancer
39
cold
34
atherosclerosis
33
AHL
33
hyperlipidemia
27
metabolic syndrome
26
cystic fibrosis
26
glucose intolerance
23
dyslipidemia
22
tumor
19
hyperinsulinemia
18
hypertension
11
Yersinia
11
cardiovascular disease
11
bacterial infection
10
hepatocellular carcinoma
9
hyperglycemia
9
SDS
9
metabolic disorder
8
abdominal obesity
8
hyperphagia
8
alcoholic fatty liver
7
sickle cell disease
7
SCD
7
EPS
7
EPS
7
Klebsiella
6
lipodystrophy
6
coronary heart disease
6
leukemia
6
carcinoma
6
Nonalcoholic fatty liver
6
sepsis
6
hypothyroidism
6
depression
6
Mycobacterium
6
breast cancer
5
pneumonia
5
infertility
5
SEM
5
tuberculosis
5
PDE
5
infectious diseases
5
hyperthyroidism
4
sepsis
4
Brown
4
arthritis
4
ketosis
4
tumor growth
4
myopathy
4
lung disease
4
liposarcoma
4
hypercholesterolemia
4
pertussis
4
virus infection
3
liver disease
3
vibriosis
3
Brucella melitensis
3
plaque
3
wasting
3
rheumatoid arthritis
3
vascular disease
3
polycystic ovary syndrome
3
Alzheimer's disease
3
arteriosclerosis
3
GSH
3
epididymis
3
worms
3
suicide
3
ichthyosis
3
muscular atrophy
3
cholera
3
diabetic ketoacidosis
3
psychological stress
3
heart failure
3
more...
Symptom
starvation
25
cachexia
14
overweight
14
twitching
7
fatigue
4
collapse
3
acute stress
2
anorexia
2
pain
1
microbial colonization
1
weakness
1
insomnia
1
diarrhea
1
agitation
1
exhaustion
1
lethargy
1
hypothermia
1
ketonuria
1
Drug
Nephron
12
Glycerol
11
Growth hormone
6
DFP
6
caffeine
6
Growth hormone
6
EPA
5
Rosiglitazone
4
lactose
4
lysine
4
MAP
3
Forskolin
3
CTX
3
EE2
3
ROS
3
Dermatol
2
Leaf
2
CTX
2
citric acid
2
Kenyan
2
Ringer's solution
2
Vitamin A
2
Glucagon
2
CCL
2
Capsicum
2
balanced salt solution
2
Azithromycin
2
CTX
2
NADH
2
Orlistat
2
FAD
2
Ethanol
2
Monit
2
ICI
1
Portal
1
Retinoic acid
1
Theophylline
1
Bosentan
1
SiO2
1
Secretin
1
FeCl3
1
Vinpocetine
1
Rimonabant
1
Homoserine Lactone
1
linolenate
1
ZnO
1
Bosentan
1
BH4
1
Protamine sulfate
1
Masoprocol
1
ADR
1
DNase I
1
DPA
1
Masoprocol
1
Salicylate
1
Monensin
1
ABC
1
DEX
1
AGG
1
Carbenoxolone
1
ascorbate
1
ALA
1
CAM
1
Papaverine
1
Cardiovasc
1
Tannic acid
1
Bifidobacterium
1
Sesamol
1
Estrogens
1
Alprenolol
1
ETA
1
Adriamycin
1
ACT
1
IFN-gamma
1
Liraglutide
1
VCR
1
ADM
1
niacin
1
Fructose
1
Enzyme
hormone-sensitive lipase
2163
lipase
273
protein kinase
254
lipoprotein lipase
212
LasR
133
AMP-activated protein kinase
95
AMPK
75
mitogen-activated protein kinase
64
acetyl-CoA carboxylase
63
CPT
58
LPL
56
cholesterol esterase
50
AMPK
44
elastase
33
phosphodiesterase
31
CPT
29
CPT
29
monoacylglycerol lipase
28
lactonase
26
protein kinase C
24
adenylate cyclase
23
ERK
20
phosphoenolpyruvate carboxykinase
19
glycerol-3-phosphate dehydrogenase
19
glycerol-3-phosphate dehydrogenase
19
deaminase
19
carboxylesterase
18
AiiA
17
acylase
17
phosphoenolpyruvate carboxykinase
16
phosphoenolpyruvate carboxykinase
16
diacylglycerol acyltransferase
16
superoxide dismutase
15
phospholipase C
14
catalase
14
luciferase
13
phosphorylase
12
acyl-CoA synthetase
12
glucose-6-phosphate dehydrogenase
11
PDK1
11
pyruvate dehydrogenase
10
pyruvate dehydrogenase
10
pyruvate dehydrogenase
10
focal adhesion kinase
10
paraoxonase
9
acyl-CoA oxidase
9
calcineurin
9
citrate synthase
9
PvdQ
9
phosphatidylinositol 3-kinase
8
cholesterol acyltransferase
8
alanine aminotransferase
8
reverse transcriptase
8
acyl-CoA synthetase
8
RNA polymerase
8
aspartate aminotransferase
8
MEK
8
6-phosphogluconate dehydrogenase
7
lactate dehydrogenase
7
6-phosphogluconate dehydrogenase
7
pyruvate kinase
7
paraoxonase
7
guanylate cyclase
7
PKG
6
adenosine deaminase
6
chitinase
6
adenosine deaminase
6
glutathione S-transferase
6
PDE
6
BAT
6
renin
6
phosphofructokinase
5
hexokinase
5
phospholipase A2
5
collagenase
5
acyl-CoA dehydrogenase
5
glycerophosphate acyltransferase
4
trypsin
4
chloramphenicol acetyltransferase
4
glutathione peroxidase
4
more...
Compound
homoserine
522
homoserine
520
homoserine
520
glucose
255
glycerol
225
Dec
130
cAMP
128
DNA
84
AMP
75
oxygen
66
water
63
Clin
49
ATP
48
serine
48
phosphate
41
CoA
39
nitrogen
35
noradrenaline
31
TNF
30
acetate
29
CPT
29
CPT
29
sodium
28
ethanol
28
Insulin
27
FFA
27
calcium
23
PMA
22
methionine
21
His
21
phenazine
20
cGMP
20
salt
18
Lead
16
zinc
14
leucine
14
hydrogen
14
alanine
14
Asp
14
heptyl
13
heptyl
13
threonine
13
palmitic acid
13
ethyl acetate
13
Oil Red O
12
Oil Red O
12
iron
12
ACTH
12
Norepinephrine
12
tyrosine
11
arginine
11
Adrenal
11
palmitic acid
11
Phe
10
Mg2+
10
SDS
10
sulfate
10
nitric oxide
9
copper
9
lysine
9
retinoic acid
9
retinol
9
cysteine
9
ammonium
9
Isoproterenol
8
THP
8
ADP
8
ammonia
8
ADP
8
NADPH
8
NADPH
8
THP
8
ADP
8
nicotinic acid
7
acetone
7
Cholesterol
7
nicotinic acid
7
adenylate
7
aldosterone
7
potassium
7
more...