Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.1.79 (hormone-sensitive lipase)
2,163 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
hormone-sensitive lipase 2163
insulin 384
adipose triglyceride lipase 303
Pseudomonas 283
lipase 219
lipoprotein lipase 205
perilipin 185
Mol 175
Sep 146
fatty acid synthase 125
peroxisome proliferator-activated receptor 109
leptin 108
epididymal 88
adiponectin 71
AMP 69
C10 68
AMP-activated protein kinase 65
FAS 63
acetyl-CoA carboxylase 61
peroxisome proliferator-activated receptor gamma 59
esterase 56
LPL 56
uncoupling protein 1 54
ATP 48
CD36 46
PKA 46
Hormone-sensitive lipase 45
AMPK 44
tumor necrosis factor 39
aP2 34
PPAR 33
cAMP-dependent protein kinase 32
DCS 32
phosphodiesterase 31
transcriptional regulator 31
adipokine 30
TNF 30
monoacylglycerol lipase 30
GLUT4 30
sterol regulatory element-binding protein 29
glucose transporter 29
CPT 29
cytokine 28
HDL 28
glucagon 27
IL-6 27
growth hormone 26
FABP4 26
SREBP-1c 26
insulin receptor 26
transcriptional activator 25
carnitine palmitoyltransferase 24
PGC 24
UCP2 24
endoplasmic reticulum 23
IRS-1 23
adenylate cyclase 22
CPT1 21
ACC 21
ERK1 21
SREBP-1 20
diacylglycerol acyltransferase 19
fatty acid binding protein 19
cholesterol esterase 19
carnitine palmitoyltransferase 1 19
AKT 18
hepatic lipase 18
ERK 18
UCP3 18
adenylyl cyclase 16
extracellular signal-regulated kinase 16
lipopolysaccharide 16
Leptin 16
MAPK 16
phosphoenolpyruvate carboxykinase 16
carboxylesterase 16
polypeptide 15
SCD1 15
glycerol-3-phosphate dehydrogenase 15
NEFA 15
more...
Disease
obesity 316
diabetes 88
FAS 63
type 2 diabetes 51
fatty liver 39
cancer 39
cold 34
atherosclerosis 33
AHL 33
hyperlipidemia 27
metabolic syndrome 26
cystic fibrosis 26
glucose intolerance 23
dyslipidemia 22
tumor 19
hyperinsulinemia 18
hypertension 11
Yersinia 11
cardiovascular disease 11
bacterial infection 10
hepatocellular carcinoma 9
hyperglycemia 9
SDS 9
metabolic disorder 8
abdominal obesity 8
hyperphagia 8
alcoholic fatty liver 7
sickle cell disease 7
SCD 7
EPS 7
EPS 7
Klebsiella 6
lipodystrophy 6
coronary heart disease 6
leukemia 6
carcinoma 6
Nonalcoholic fatty liver 6
sepsis 6
hypothyroidism 6
depression 6
Mycobacterium 6
breast cancer 5
pneumonia 5
infertility 5
SEM 5
tuberculosis 5
PDE 5
infectious diseases 5
hyperthyroidism 4
sepsis 4
Brown 4
arthritis 4
ketosis 4
tumor growth 4
myopathy 4
lung disease 4
liposarcoma 4
hypercholesterolemia 4
pertussis 4
virus infection 3
liver disease 3
vibriosis 3
Brucella melitensis 3
plaque 3
wasting 3
rheumatoid arthritis 3
vascular disease 3
polycystic ovary syndrome 3
Alzheimer's disease 3
arteriosclerosis 3
GSH 3
epididymis 3
worms 3
suicide 3
ichthyosis 3
muscular atrophy 3
cholera 3
diabetic ketoacidosis 3
psychological stress 3
heart failure 3
more...
Symptom
starvation 25
cachexia 14
overweight 14
twitching 7
fatigue 4
collapse 3
acute stress 2
anorexia 2
pain 1
microbial colonization 1
weakness 1
insomnia 1
diarrhea 1
agitation 1
exhaustion 1
lethargy 1
hypothermia 1
ketonuria 1
Drug
Nephron 12
Glycerol 11
Growth hormone 6
DFP 6
caffeine 6
Growth hormone 6
EPA 5
Rosiglitazone 4
lactose 4
lysine 4
MAP 3
Forskolin 3
CTX 3
EE2 3
ROS 3
Dermatol 2
Leaf 2
CTX 2
citric acid 2
Kenyan 2
Ringer's solution 2
Vitamin A 2
Glucagon 2
CCL 2
Capsicum 2
balanced salt solution 2
Azithromycin 2
CTX 2
NADH 2
Orlistat 2
FAD 2
Ethanol 2
Monit 2
ICI 1
Portal 1
Retinoic acid 1
Theophylline 1
Bosentan 1
SiO2 1
Secretin 1
FeCl3 1
Vinpocetine 1
Rimonabant 1
Homoserine Lactone 1
linolenate 1
ZnO 1
Bosentan 1
BH4 1
Protamine sulfate 1
Masoprocol 1
ADR 1
DNase I 1
DPA 1
Masoprocol 1
Salicylate 1
Monensin 1
ABC 1
DEX 1
AGG 1
Carbenoxolone 1
ascorbate 1
ALA 1
CAM 1
Papaverine 1
Cardiovasc 1
Tannic acid 1
Bifidobacterium 1
Sesamol 1
Estrogens 1
Alprenolol 1
ETA 1
Adriamycin 1
ACT 1
IFN-gamma 1
Liraglutide 1
VCR 1
ADM 1
niacin 1
Fructose 1
Enzyme
hormone-sensitive lipase 2163
lipase 273
protein kinase 254
lipoprotein lipase 212
LasR 133
AMP-activated protein kinase 95
AMPK 75
mitogen-activated protein kinase 64
acetyl-CoA carboxylase 63
CPT 58
LPL 56
cholesterol esterase 50
AMPK 44
elastase 33
phosphodiesterase 31
CPT 29
CPT 29
monoacylglycerol lipase 28
lactonase 26
protein kinase C 24
adenylate cyclase 23
ERK 20
phosphoenolpyruvate carboxykinase 19
glycerol-3-phosphate dehydrogenase 19
glycerol-3-phosphate dehydrogenase 19
deaminase 19
carboxylesterase 18
AiiA 17
acylase 17
phosphoenolpyruvate carboxykinase 16
phosphoenolpyruvate carboxykinase 16
diacylglycerol acyltransferase 16
superoxide dismutase 15
phospholipase C 14
catalase 14
luciferase 13
phosphorylase 12
acyl-CoA synthetase 12
glucose-6-phosphate dehydrogenase 11
PDK1 11
pyruvate dehydrogenase 10
pyruvate dehydrogenase 10
pyruvate dehydrogenase 10
focal adhesion kinase 10
paraoxonase 9
acyl-CoA oxidase 9
calcineurin 9
citrate synthase 9
PvdQ 9
phosphatidylinositol 3-kinase 8
cholesterol acyltransferase 8
alanine aminotransferase 8
reverse transcriptase 8
acyl-CoA synthetase 8
RNA polymerase 8
aspartate aminotransferase 8
MEK 8
6-phosphogluconate dehydrogenase 7
lactate dehydrogenase 7
6-phosphogluconate dehydrogenase 7
pyruvate kinase 7
paraoxonase 7
guanylate cyclase 7
PKG 6
adenosine deaminase 6
chitinase 6
adenosine deaminase 6
glutathione S-transferase 6
PDE 6
BAT 6
renin 6
phosphofructokinase 5
hexokinase 5
phospholipase A2 5
collagenase 5
acyl-CoA dehydrogenase 5
glycerophosphate acyltransferase 4
trypsin 4
chloramphenicol acetyltransferase 4
glutathione peroxidase 4
more...
Compound
homoserine 522
homoserine 520
homoserine 520
glucose 255
glycerol 225
Dec 130
cAMP 128
DNA 84
AMP 75
oxygen 66
water 63
Clin 49
ATP 48
serine 48
phosphate 41
CoA 39
nitrogen 35
noradrenaline 31
TNF 30
acetate 29
CPT 29
CPT 29
sodium 28
ethanol 28
Insulin 27
FFA 27
calcium 23
PMA 22
methionine 21
His 21
phenazine 20
cGMP 20
salt 18
Lead 16
zinc 14
leucine 14
hydrogen 14
alanine 14
Asp 14
heptyl 13
heptyl 13
threonine 13
palmitic acid 13
ethyl acetate 13
Oil Red O 12
Oil Red O 12
iron 12
ACTH 12
Norepinephrine 12
tyrosine 11
arginine 11
Adrenal 11
palmitic acid 11
Phe 10
Mg2+ 10
SDS 10
sulfate 10
nitric oxide 9
copper 9
lysine 9
retinoic acid 9
retinol 9
cysteine 9
ammonium 9
Isoproterenol 8
THP 8
ADP 8
ammonia 8
ADP 8
NADPH 8
NADPH 8
THP 8
ADP 8
nicotinic acid 7
acetone 7
Cholesterol 7
nicotinic acid 7
adenylate 7
aldosterone 7
potassium 7
more...