Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.1.79 (
hormone-sensitive lipase
)
2,163
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
hormone-sensitive lipase
2163
insulin
384
adipose triglyceride lipase
303
Pseudomonas
283
lipase
219
lipoprotein lipase
205
perilipin
185
Mol
175
Sep
146
fatty acid synthase
125
peroxisome proliferator-activated receptor
109
leptin
108
epididymal
88
adiponectin
71
AMP
69
C10
68
AMP-activated protein kinase
65
FAS
63
acetyl-CoA carboxylase
61
peroxisome proliferator-activated receptor gamma
59
esterase
56
LPL
56
uncoupling protein 1
54
ATP
48
PKA
46
CD36
46
Hormone-sensitive lipase
45
AMPK
44
tumor necrosis factor
39
aP2
34
PPAR
33
DCS
32
cAMP-dependent protein kinase
32
phosphodiesterase
31
transcriptional regulator
31
TNF
30
monoacylglycerol lipase
30
GLUT4
30
adipokine
30
CPT
29
more...
Disease
obesity
316
diabetes
88
FAS
63
type 2 diabetes
51
fatty liver
39
cancer
39
cold
34
AHL
33
atherosclerosis
33
hyperlipidemia
27
cystic fibrosis
26
metabolic syndrome
26
glucose intolerance
23
dyslipidemia
22
tumor
19
hyperinsulinemia
18
hypertension
11
Yersinia
11
cardiovascular disease
11
bacterial infection
10
SDS
9
hepatocellular carcinoma
9
hyperglycemia
9
metabolic disorder
8
hyperphagia
8
abdominal obesity
8
alcoholic fatty liver
7
SCD
7
EPS
7
sickle cell disease
7
EPS
7
depression
6
carcinoma
6
leukemia
6
Klebsiella
6
lipodystrophy
6
coronary heart disease
6
Nonalcoholic fatty liver
6
sepsis
6
Mycobacterium
6
more...
Symptom
starvation
25
cachexia
14
overweight
14
twitching
7
fatigue
4
collapse
3
acute stress
2
anorexia
2
pain
1
microbial colonization
1
weakness
1
insomnia
1
diarrhea
1
agitation
1
exhaustion
1
lethargy
1
hypothermia
1
ketonuria
1
Drug
Nephron
12
Glycerol
11
caffeine
6
Growth hormone
6
DFP
6
Growth hormone
6
EPA
5
Rosiglitazone
4
lysine
4
lactose
4
Forskolin
3
EE2
3
MAP
3
CTX
3
ROS
3
Capsicum
2
balanced salt solution
2
Leaf
2
Kenyan
2
Orlistat
2
FAD
2
CCL
2
Dermatol
2
Vitamin A
2
Ringer's solution
2
Azithromycin
2
Ethanol
2
CTX
2
NADH
2
CTX
2
citric acid
2
Glucagon
2
Monit
2
AGG
1
ascorbate
1
Portal
1
Bosentan
1
SiO2
1
Vinpocetine
1
Rimonabant
1
more...
Enzyme
hormone-sensitive lipase
2163
lipase
273
protein kinase
254
lipoprotein lipase
212
LasR
133
AMP-activated protein kinase
95
AMPK
75
mitogen-activated protein kinase
64
acetyl-CoA carboxylase
63
CPT
58
LPL
56
cholesterol esterase
50
AMPK
44
elastase
33
phosphodiesterase
31
CPT
29
CPT
29
monoacylglycerol lipase
28
lactonase
26
protein kinase C
24
adenylate cyclase
23
ERK
20
phosphoenolpyruvate carboxykinase
19
glycerol-3-phosphate dehydrogenase
19
deaminase
19
glycerol-3-phosphate dehydrogenase
19
carboxylesterase
18
AiiA
17
acylase
17
phosphoenolpyruvate carboxykinase
16
diacylglycerol acyltransferase
16
phosphoenolpyruvate carboxykinase
16
superoxide dismutase
15
phospholipase C
14
catalase
14
luciferase
13
acyl-CoA synthetase
12
phosphorylase
12
PDK1
11
glucose-6-phosphate dehydrogenase
11
more...
Compound
homoserine
522
homoserine
520
homoserine
520
glucose
255
glycerol
225
Dec
130
cAMP
128
DNA
84
AMP
75
oxygen
66
water
63
Clin
49
ATP
48
serine
48
phosphate
41
CoA
39
nitrogen
35
noradrenaline
31
TNF
30
acetate
29
CPT
29
CPT
29
ethanol
28
sodium
28
Insulin
27
FFA
27
calcium
23
PMA
22
His
21
methionine
21
cGMP
20
phenazine
20
salt
18
Lead
16
leucine
14
Asp
14
alanine
14
zinc
14
hydrogen
14
heptyl
13
more...