Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.1.7 (
acetylcholinesterase
)
28,390
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
acetylcholinesterase
20812
butyrylcholinesterase
2506
Sep
1972
AChE
1534
choline acetyltransferase
1238
Mol
869
catalase
858
superoxide dismutase
722
esterase
616
muscarinic receptor
476
amyloid precursor protein
434
GSH
427
ATPase
419
alkaline phosphatase
417
NMR
413
Cholinesterase
409
lactate dehydrogenase
389
glutathione S-transferase
380
glutathione peroxidase
373
carboxylesterase
372
acetylcholine receptor
326
albumin
323
axonal
318
nicotinic acetylcholine receptor
279
membrane-bound
268
CA1
255
collagen
246
substance P
244
tyrosine hydroxylase
240
pseudocholinesterase
228
peroxidase
225
aspartate aminotransferase
224
nerve growth factor
215
hemoglobin
201
olfactory
200
alanine aminotransferase
199
serum albumin
194
GABA
188
ATP
183
polypeptide
181
glucosidase
181
TNF
168
glutathione reductase
168
tyrosinase
167
caspase-3
164
amylase
162
insulin
162
acid phosphatase
158
amyloid beta
154
NMDA receptor
152
endoplasmic reticulum
148
brain-derived neurotrophic factor
145
microsomal
144
somatostatin
142
cytochrome P450
139
Choline acetyltransferase
136
glial fibrillary acidic protein
135
nitric oxide synthase
133
paraoxonase
127
tumor necrosis factor
119
SDS
113
CA3
112
gut
110
neuropathy target esterase
108
cytokine
105
SOD
105
alpha-fetoprotein
105
ESI
104
dimeric
103
muscarinic acetylcholine receptor
102
calcitonin
102
ACS
101
MAO-B
100
BACE1
98
5-hydroxytryptamine
97
AMP
95
CAT
95
neuropeptide Y
91
lipopolysaccharide
89
creatine kinase
89
more...
Disease
Alzheimer's disease
4380
dementia
1328
cognitive impairment
709
depression
552
GSH
427
memory impairment
367
Parkinson's disease
352
neuroblastoma
299
cancer
291
myasthenia gravis
288
diabetes
269
fits
189
tumor
165
amnesia
156
cirrhosis
155
plaque
130
psychosis
130
schizophrenia
119
neuropathy
113
SDS
113
Evans
108
hallucinations
105
hypertension
103
epilepsy
101
ischemia
100
varices
97
stroke
93
worms
88
cognitive deficit
88
Huntington's disease
85
cold
78
malaria
77
Dementia with Lewy bodies
73
obesity
73
myasthenia
68
parkinsonism
67
hepatocellular carcinoma
66
respiratory failure
66
status epilepticus
64
SEM
64
senile dementia
63
leukemia
63
liver disease
61
pheochromocytoma
60
hyperglycemia
58
malnutrition
54
Down syndrome
54
delusions
53
delirium
51
PAM
51
myopathy
51
glaucoma
48
autoimmune disease
47
multiple sclerosis
46
type 2 diabetes
46
prolapse
46
anemia
45
West
45
asthma
44
MCF
44
SAR
43
SCH
42
suicide
42
carcinoma
41
heart failure
41
dysplasia
40
amyotrophic lateral sclerosis
39
chronic hepatitis
38
cardiovascular disease
38
uterus
38
hypothyroidism
37
breast cancer
36
HIV
35
hepatitis
34
cerebral ischemia
34
coma
33
plague
32
sepsis
32
aggression
32
muscular dystrophy
31
more...
Symptom
seizures
343
anesthesia
260
weakness
235
memory loss
136
pain
113
diarrhea
103
vomiting
90
tremor
88
hypothermia
85
nausea
84
ACHE
84
agitation
79
fatigue
71
headache
62
ataxia
60
constipation
53
apathy
51
functional recovery
43
analgesia
43
dizziness
42
respiratory distress
40
fasciculation
33
syncope
30
collapse
27
anorexia
26
sleepiness
26
insomnia
26
dyspnea
23
exhaustion
22
abdominal pain
21
chronic constipation
19
nausea and vomiting
19
dystonia
18
incoordination
18
twitching
18
cough
18
acute stress
16
blurred vision
15
splenomegaly
15
starvation
15
lethargy
14
skin irritation
13
visual hallucination
12
myalgia
12
Ill
11
paresis
11
ophthalmoplegia
11
erythema
11
overweight
11
spasm
11
thinning
10
acidity
10
hypercapnia
10
bradykinesia
10
rhinorrhea
9
paresthesia
9
asthenia
9
spasticity
9
hypotonia
9
myoclonus
8
muscle cramps
8
despair
8
flushing
8
vertigo
6
loss of equilibrium
6
Depressive symptoms
6
discomfort
6
numbness
5
angina
5
epigastric pain
5
dysarthria
5
Decreased activity
5
heartburn
5
cyanosis
4
pallor
4
hepatomegaly
4
wheezing
4
Behavioral symptoms
4
hypoproteinemia
4
discomfort
4
more...
Drug
Donepezil
354
DFP
202
Atropine
170
vitamin E
107
Scopolamine
102
THA
94
CSF
71
ROS
71
Aricept
59
lysine
55
ascorbate
54
NADH
54
caffeine
50
Monit
45
Galanthamine
43
Ethanol
41
Pyridostigmine bromide
40
Glutathione
37
EDR
35
Pralidoxime
35
p75
34
Nephron
33
Gel
32
Pyridostigmine bromide
30
Vitamin E
24
EPA
24
Leaf
24
Dermatol
23
TAK
20
Exelon
20
EE2
20
Asn
19
CPT-11
18
Exelon
18
Reminyl
18
Cardiovasc
17
ENT
17
citric acid
16
ZnO
15
IL-2
15
CTX
15
Albumin
15
ALA
14
Ranitidine
13
PCP
13
Portal
13
Mestinon
13
HCH
13
Cognex
12
Spectrum
12
Biopolymers
12
Kainic acid
11
Galantamine hydrobromide
11
Fraction
11
CaCl2
11
Clonidine
11
Distigmine bromide
11
Piracetam
11
CaCl2
11
CaCl2
11
Ginseng
10
Ringer's solution
10
Tubocurarine
10
PCB
10
TAC
10
TiO2
9
Brij 96
9
Serum albumin
9
niacin
9
CoCl2
9
Irinotecan
9
Rutin
9
Indomethacin
9
Pilocarpine
9
CoCl2
9
MAP
8
Senna
8
MRC
8
Forskolin
8
Reserpine
8
more...
Enzyme
acetylcholinesterase
28390
cholinesterase
11108
choline acetyltransferase
1266
catalase
901
superoxide dismutase
791
ATPase
479
glutathione S-transferase
443
alkaline phosphatase
432
lactate dehydrogenase
429
carboxylesterase
416
glutathione peroxidase
376
peroxidase
348
monoamine oxidase
324
alanine aminotransferase
315
aspartate aminotransferase
277
tyrosine hydroxylase
228
paraoxonase
171
tyrosinase
167
glutathione reductase
167
acid phosphatase
161
paraoxonase
150
NADPH-diaphorase
141
trypsin
137
caspase-3
126
choline oxidase
125
creatine kinase
117
succinate dehydrogenase
117
mitogen-activated protein kinase
117
protein kinase
114
neuropathy target esterase
114
diaphorase
111
gamma-glutamyl transpeptidase
111
cytochrome oxidase
104
ACS
101
phospholipase C
99
lipase
95
NQO1
87
glucose-6-phosphate dehydrogenase
86
carbonic anhydrase
85
5'-nucleotidase
85
protein kinase C
84
diaphorase
82
ERK
81
collagenase
74
phosphodiesterase
73
ACE
63
NO synthase
63
lipoxygenase
62
adenylate cyclase
55
chymotrypsin
51
PAM
51
succinic dehydrogenase
50
AST
48
phospholipase A2
47
glutamate dehydrogenase
45
glutamate dehydrogenase
45
glutamate dehydrogenase
45
GSK
44
adenosine deaminase
43
glutamate decarboxylase
43
deaminase
43
adenosine deaminase
43
urease
38
urease
38
aldolase
35
thrombin
35
hexokinase
33
malate dehydrogenase
33
arginase
33
phosphorylase
32
CD10
31
leucine aminopeptidase
31
CYP3A4
31
neuraminidase
29
isocitrate dehydrogenase
29
lysozyme
29
beta-secretase
28
CPR
28
dopamine beta-hydroxylase
28
glucose-6-phosphatase
27
more...
Compound
Dec
1980
water
1861
Clin
840
sodium
682
calcium
664
oxygen
604
DNA
591
ACh
591
glucose
511
phosphate
509
GSH
456
GSH
456
glutamate
406
hydrogen
390
galanthamine
376
acetate
355
nitric oxide
326
ethanol
315
serine
301
iodine
286
bromide
277
salt
268
potassium
262
PAM
260
nitrogen
252
methanol
252
sulfate
248
DPPH
239
silver
222
Physostigmine
222
copper
210
noradrenaline
208
Triton X-100
202
urea
201
ethyl acetate
199
GABA
195
GABA
191
ATP
185
5-HT
181
creatinine
172
zinc
171
Atropine
170
Chlorpyrifos
169
TNF
168
Tacrine
166
galactose
165
His
162
pyridine
159
ammonium
158
iron
150
arginine
142
phosphorus
142
tyrosine
142
DDVP
138
OMPA
130
cadmium
129
cysteine
125
NMDA
124
SDS
121
Rivastigmine
119
gamma-aminobutyric acid
117
hexane
111
cAMP
111
alanine
108
Soman
104
ACS
101
ACS
101
SEE
100
leucine
99
methionine
99
QNB
99
AMP
97
piperidine
97
piperidine
97
MDA
96
CAT
96
CAT
95
CAT
95
Pyridostigmine
94
aluminum
93
more...