Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.1.7 (acetylcholinesterase)
28,390 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
acetylcholinesterase 20812
butyrylcholinesterase 2506
Sep 1972
AChE 1534
choline acetyltransferase 1238
Mol 869
catalase 858
superoxide dismutase 722
esterase 616
muscarinic receptor 476
amyloid precursor protein 434
GSH 427
ATPase 419
alkaline phosphatase 417
NMR 413
Cholinesterase 409
lactate dehydrogenase 389
glutathione S-transferase 380
glutathione peroxidase 373
carboxylesterase 372
acetylcholine receptor 326
albumin 323
axonal 318
nicotinic acetylcholine receptor 279
membrane-bound 268
CA1 255
collagen 246
substance P 244
tyrosine hydroxylase 240
pseudocholinesterase 228
peroxidase 225
aspartate aminotransferase 224
nerve growth factor 215
hemoglobin 201
olfactory 200
alanine aminotransferase 199
serum albumin 194
GABA 188
ATP 183
polypeptide 181
glucosidase 181
TNF 168
glutathione reductase 168
tyrosinase 167
caspase-3 164
amylase 162
insulin 162
acid phosphatase 158
amyloid beta 154
NMDA receptor 152
endoplasmic reticulum 148
brain-derived neurotrophic factor 145
microsomal 144
somatostatin 142
cytochrome P450 139
Choline acetyltransferase 136
glial fibrillary acidic protein 135
nitric oxide synthase 133
paraoxonase 127
tumor necrosis factor 119
SDS 113
CA3 112
gut 110
neuropathy target esterase 108
cytokine 105
SOD 105
alpha-fetoprotein 105
ESI 104
dimeric 103
muscarinic acetylcholine receptor 102
calcitonin 102
ACS 101
MAO-B 100
BACE1 98
5-hydroxytryptamine 97
AMP 95
CAT 95
neuropeptide Y 91
lipopolysaccharide 89
creatine kinase 89
more...
Disease
Alzheimer's disease 4380
dementia 1328
cognitive impairment 709
depression 552
GSH 427
memory impairment 367
Parkinson's disease 352
neuroblastoma 299
cancer 291
myasthenia gravis 288
diabetes 269
fits 189
tumor 165
amnesia 156
cirrhosis 155
plaque 130
psychosis 130
schizophrenia 119
neuropathy 113
SDS 113
Evans 108
hallucinations 105
hypertension 103
epilepsy 101
ischemia 100
varices 97
stroke 93
worms 88
cognitive deficit 88
Huntington's disease 85
cold 78
malaria 77
Dementia with Lewy bodies 73
obesity 73
myasthenia 68
parkinsonism 67
hepatocellular carcinoma 66
respiratory failure 66
status epilepticus 64
SEM 64
senile dementia 63
leukemia 63
liver disease 61
pheochromocytoma 60
hyperglycemia 58
malnutrition 54
Down syndrome 54
delusions 53
delirium 51
PAM 51
myopathy 51
glaucoma 48
autoimmune disease 47
multiple sclerosis 46
type 2 diabetes 46
prolapse 46
anemia 45
West 45
asthma 44
MCF 44
SAR 43
SCH 42
suicide 42
carcinoma 41
heart failure 41
dysplasia 40
amyotrophic lateral sclerosis 39
chronic hepatitis 38
cardiovascular disease 38
uterus 38
hypothyroidism 37
breast cancer 36
HIV 35
hepatitis 34
cerebral ischemia 34
coma 33
plague 32
sepsis 32
aggression 32
muscular dystrophy 31
more...
Symptom
seizures 343
anesthesia 260
weakness 235
memory loss 136
pain 113
diarrhea 103
vomiting 90
tremor 88
hypothermia 85
nausea 84
ACHE 84
agitation 79
fatigue 71
headache 62
ataxia 60
constipation 53
apathy 51
functional recovery 43
analgesia 43
dizziness 42
respiratory distress 40
fasciculation 33
syncope 30
collapse 27
anorexia 26
sleepiness 26
insomnia 26
dyspnea 23
exhaustion 22
abdominal pain 21
chronic constipation 19
nausea and vomiting 19
dystonia 18
incoordination 18
twitching 18
cough 18
acute stress 16
blurred vision 15
splenomegaly 15
starvation 15
lethargy 14
skin irritation 13
visual hallucination 12
myalgia 12
Ill 11
paresis 11
ophthalmoplegia 11
erythema 11
overweight 11
spasm 11
thinning 10
acidity 10
hypercapnia 10
bradykinesia 10
rhinorrhea 9
paresthesia 9
asthenia 9
spasticity 9
hypotonia 9
myoclonus 8
muscle cramps 8
despair 8
flushing 8
vertigo 6
loss of equilibrium 6
Depressive symptoms 6
discomfort 6
numbness 5
angina 5
epigastric pain 5
dysarthria 5
Decreased activity 5
heartburn 5
cyanosis 4
pallor 4
hepatomegaly 4
wheezing 4
Behavioral symptoms 4
hypoproteinemia 4
discomfort 4
more...
Drug
Donepezil 354
DFP 202
Atropine 170
vitamin E 107
Scopolamine 102
THA 94
CSF 71
ROS 71
Aricept 59
lysine 55
ascorbate 54
NADH 54
caffeine 50
Monit 45
Galanthamine 43
Ethanol 41
Pyridostigmine bromide 40
Glutathione 37
EDR 35
Pralidoxime 35
p75 34
Nephron 33
Gel 32
Pyridostigmine bromide 30
Vitamin E 24
EPA 24
Leaf 24
Dermatol 23
TAK 20
Exelon 20
EE2 20
Asn 19
CPT-11 18
Exelon 18
Reminyl 18
Cardiovasc 17
ENT 17
citric acid 16
ZnO 15
IL-2 15
CTX 15
Albumin 15
ALA 14
Ranitidine 13
PCP 13
Portal 13
Mestinon 13
HCH 13
Cognex 12
Spectrum 12
Biopolymers 12
Kainic acid 11
Galantamine hydrobromide 11
Fraction 11
CaCl2 11
Clonidine 11
Distigmine bromide 11
Piracetam 11
CaCl2 11
CaCl2 11
Ginseng 10
Ringer's solution 10
Tubocurarine 10
PCB 10
TAC 10
TiO2 9
Brij 96 9
Serum albumin 9
niacin 9
CoCl2 9
Irinotecan 9
Rutin 9
Indomethacin 9
Pilocarpine 9
CoCl2 9
MAP 8
Senna 8
MRC 8
Forskolin 8
Reserpine 8
more...
Enzyme
acetylcholinesterase 28390
cholinesterase 11108
choline acetyltransferase 1266
catalase 901
superoxide dismutase 791
ATPase 479
glutathione S-transferase 443
alkaline phosphatase 432
lactate dehydrogenase 429
carboxylesterase 416
glutathione peroxidase 376
peroxidase 348
monoamine oxidase 324
alanine aminotransferase 315
aspartate aminotransferase 277
tyrosine hydroxylase 228
paraoxonase 171
tyrosinase 167
glutathione reductase 167
acid phosphatase 161
paraoxonase 150
NADPH-diaphorase 141
trypsin 137
caspase-3 126
choline oxidase 125
creatine kinase 117
succinate dehydrogenase 117
mitogen-activated protein kinase 117
protein kinase 114
neuropathy target esterase 114
diaphorase 111
gamma-glutamyl transpeptidase 111
cytochrome oxidase 104
ACS 101
phospholipase C 99
lipase 95
NQO1 87
glucose-6-phosphate dehydrogenase 86
carbonic anhydrase 85
5'-nucleotidase 85
protein kinase C 84
diaphorase 82
ERK 81
collagenase 74
phosphodiesterase 73
ACE 63
NO synthase 63
lipoxygenase 62
adenylate cyclase 55
chymotrypsin 51
PAM 51
succinic dehydrogenase 50
AST 48
phospholipase A2 47
glutamate dehydrogenase 45
glutamate dehydrogenase 45
glutamate dehydrogenase 45
GSK 44
adenosine deaminase 43
glutamate decarboxylase 43
deaminase 43
adenosine deaminase 43
urease 38
urease 38
aldolase 35
thrombin 35
hexokinase 33
malate dehydrogenase 33
arginase 33
phosphorylase 32
CD10 31
leucine aminopeptidase 31
CYP3A4 31
neuraminidase 29
isocitrate dehydrogenase 29
lysozyme 29
beta-secretase 28
CPR 28
dopamine beta-hydroxylase 28
glucose-6-phosphatase 27
more...
Compound
Dec 1980
water 1861
Clin 840
sodium 682
calcium 664
oxygen 604
DNA 591
ACh 591
glucose 511
phosphate 509
GSH 456
GSH 456
glutamate 406
hydrogen 390
galanthamine 376
acetate 355
nitric oxide 326
ethanol 315
serine 301
iodine 286
bromide 277
salt 268
potassium 262
PAM 260
nitrogen 252
methanol 252
sulfate 248
DPPH 239
silver 222
Physostigmine 222
copper 210
noradrenaline 208
Triton X-100 202
urea 201
ethyl acetate 199
GABA 195
GABA 191
ATP 185
5-HT 181
creatinine 172
zinc 171
Atropine 170
Chlorpyrifos 169
TNF 168
Tacrine 166
galactose 165
His 162
pyridine 159
ammonium 158
iron 150
arginine 142
phosphorus 142
tyrosine 142
DDVP 138
OMPA 130
cadmium 129
cysteine 125
NMDA 124
SDS 121
Rivastigmine 119
gamma-aminobutyric acid 117
hexane 111
cAMP 111
alanine 108
Soman 104
ACS 101
ACS 101
SEE 100
leucine 99
methionine 99
QNB 99
AMP 97
piperidine 97
piperidine 97
MDA 96
CAT 96
CAT 95
CAT 95
Pyridostigmine 94
aluminum 93
more...