Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.1.7 (acetylcholinesterase)
28,390 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

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Human Gene/Protein
acetylcholinesterase 20812
butyrylcholinesterase 2506
Sep 1972
AChE 1534
choline acetyltransferase 1238
Mol 869
catalase 858
superoxide dismutase 722
esterase 616
muscarinic receptor 476
amyloid precursor protein 434
GSH 427
ATPase 419
alkaline phosphatase 417
NMR 413
Cholinesterase 409
lactate dehydrogenase 389
glutathione S-transferase 380
glutathione peroxidase 373
carboxylesterase 372
acetylcholine receptor 326
albumin 323
axonal 318
nicotinic acetylcholine receptor 279
membrane-bound 268
CA1 255
collagen 246
substance P 244
tyrosine hydroxylase 240
pseudocholinesterase 228
peroxidase 225
aspartate aminotransferase 224
nerve growth factor 215
hemoglobin 201
olfactory 200
alanine aminotransferase 199
serum albumin 194
GABA 188
ATP 183
polypeptide 181
glucosidase 181
glutathione reductase 168
TNF 168
tyrosinase 167
caspase-3 164
amylase 162
insulin 162
acid phosphatase 158
amyloid beta 154
NMDA receptor 152
endoplasmic reticulum 148
brain-derived neurotrophic factor 145
microsomal 144
somatostatin 142
cytochrome P450 139
Choline acetyltransferase 136
glial fibrillary acidic protein 135
nitric oxide synthase 133
paraoxonase 127
tumor necrosis factor 119
SDS 113
CA3 112
gut 110
neuropathy target esterase 108
SOD 105
cytokine 105
alpha-fetoprotein 105
ESI 104
dimeric 103
muscarinic acetylcholine receptor 102
calcitonin 102
ACS 101
MAO-B 100
BACE1 98
5-hydroxytryptamine 97
AMP 95
CAT 95
neuropeptide Y 91
creatine kinase 89
GST 89
lipopolysaccharide 89
lipase 88
metallothionein 86
5'-nucleotidase 84
calbindin 83
IL-6 82
Gen 81
antioxidant enzyme 81
diaphorase 80
prothrombin 79
Pol 79
carbonic anhydrase 79
carp 78
arylesterase 77
MAO-A 76
glycoprotein 76
megakaryocyte 74
glucose-6-phosphate dehydrogenase 74
collagenase 73
thymus 72
ROS 71
Bcl-2 71
vesicular acetylcholine transporter 70
phosphodiesterase 70
LDH 70
ACHE 69
cytochrome 69
ADAS 69
parvalbumin 67
tau protein 67
NADPH 65
APP 65
DDT 64
FRAP 63
CSF 63
xenobiotic 63
lipoxygenase 62
erythroid 62
growth hormone 61
vasoactive intestinal peptide 60
phosphatidylinositol-specific 59
glutamic acid decarboxylase 59
synaptophysin 57
fused 56
myeloperoxidase 56
adenosine triphosphatase 56
interleukin-6 55
ChAT 55
lectin 54
hole 53
inducible nitric oxide synthase 53
calretinin 53
adenylate cyclase 53
P450 52
choline transporter 52
membrane protein 51
NADH 51
PAM 51
MRI 50
AChR 50
neurotrophic factor 50
TOF 49
AST 49
Pseudomonas 49
CAS 48
beta-endorphin 48
Carboxylesterase 48
Rec 48
BACE 47
vasoactive intestinal peptide (VIP) 47
brain) 46
transferrin 46
proline-rich 46
calcium channel 45
GABA(A) receptor 45
thyroid hormone 44
agrin 44
GPT 43
neurotrophin 43
SAR 43
more...
Disease
Alzheimer's disease 4380
dementia 1328
cognitive impairment 709
depression 552
GSH 427
memory impairment 367
Parkinson's disease 352
neuroblastoma 299
cancer 291
myasthenia gravis 288
diabetes 269
fits 189
tumor 165
amnesia 156
cirrhosis 155
psychosis 130
plaque 130
schizophrenia 119
neuropathy 113
SDS 113
Evans 108
hallucinations 105
hypertension 103
epilepsy 101
ischemia 100
varices 97
stroke 93
cognitive deficit 88
worms 88
Huntington's disease 85
cold 78
malaria 77
obesity 73
Dementia with Lewy bodies 73
myasthenia 68
parkinsonism 67
respiratory failure 66
hepatocellular carcinoma 66
status epilepticus 64
SEM 64
senile dementia 63
leukemia 63
liver disease 61
pheochromocytoma 60
hyperglycemia 58
malnutrition 54
Down syndrome 54
delusions 53
myopathy 51
delirium 51
PAM 51
glaucoma 48
autoimmune disease 47
multiple sclerosis 46
prolapse 46
type 2 diabetes 46
anemia 45
West 45
MCF 44
asthma 44
SAR 43
SCH 42
suicide 42
heart failure 41
carcinoma 41
dysplasia 40
amyotrophic lateral sclerosis 39
uterus 38
cardiovascular disease 38
chronic hepatitis 38
hypothyroidism 37
breast cancer 36
HIV 35
cerebral ischemia 34
hepatitis 34
coma 33
sepsis 32
plague 32
aggression 32
muscular dystrophy 31
sepsis 31
paroxysmal nocturnal hemoglobinuria 30
tetanus 30
polyneuropathy 30
confusion 30
thrombocytopenia 29
encephalopathy 28
dengue 27
mole 27
NAME 27
thymoma 27
myocardial infarction 27
Best 27
Vascular dementia 26
lung cancer 26
autism 26
fatty liver 26
diplopia 26
mental illness 26
major depressive disorder 25
hyperlipidemia 25
mole 25
chronic liver disease 24
Steroids 24
progressive supranuclear palsy 24
hypercholesterolemia 23
atherosclerosis 23
cornea 23
schistosomiasis 23
DBA 23
Schistosoma mansoni 22
neurological disease 22
disinhibition 22
dysphagia 22
TEM 22
addiction 22
sleep disorders 21
vascular disease 21
amyloidosis 20
TEM 20
bowel obstruction 20
PND 19
glioma 19
Enzyme inhibition 19
bipolar disorder 19
Thymus 19
Duchenne muscular dystrophy 19
PDB 19
Thymus 19
sleep disturbances 19
Thymus 19
hyperhomocysteinemia 19
dehydration 18
hepatitis B 18
incontinence 18
pneumonia 18
liver cancer 18
dyspepsia 17
PDE 17
NMS 17
intraocular pressure 17
catalepsy 17
brain atrophy 17
hyperthyroidism 17
tumorigenesis 17
pulmonary edema 17
peripheral neuropathy 17
megacolon 16
abortion 16
melanoma 16
Syndrome 16
psychological stress 16
brain dysfunction 16
NMS 16
CNS diseases 16
cholestasis 16
urethra 16
PCP 16
pertussis 15
posttraumatic stress disorder 15
more...
Symptom
seizures 343
anesthesia 260
weakness 235
memory loss 136
pain 113
diarrhea 103
vomiting 90
tremor 88
hypothermia 85
ACHE 84
nausea 84
agitation 79
fatigue 71
headache 62
ataxia 60
constipation 53
apathy 51
analgesia 43
functional recovery 43
dizziness 42
respiratory distress 40
fasciculation 33
syncope 30
collapse 27
insomnia 26
sleepiness 26
anorexia 26
dyspnea 23
exhaustion 22
abdominal pain 21
nausea and vomiting 19
chronic constipation 19
twitching 18
dystonia 18
incoordination 18
cough 18
acute stress 16
splenomegaly 15
starvation 15
blurred vision 15
lethargy 14
skin irritation 13
myalgia 12
visual hallucination 12
overweight 11
ophthalmoplegia 11
erythema 11
Ill 11
paresis 11
spasm 11
hypercapnia 10
acidity 10
thinning 10
bradykinesia 10
asthenia 9
hypotonia 9
spasticity 9
rhinorrhea 9
paresthesia 9
muscle cramps 8
myoclonus 8
despair 8
flushing 8
discomfort 6
Depressive symptoms 6
vertigo 6
loss of equilibrium 6
angina 5
dysarthria 5
numbness 5
epigastric pain 5
Decreased activity 5
heartburn 5
discomfort 4
cyanosis 4
hepatomegaly 4
Behavioral symptoms 4
wheezing 4
hypoproteinemia 4
forgetfulness 4
shortness of breath 4
rundown 4
pallor 4
colic 4
Sedation 4
ENT 4
torticollis 3
masculinization 3
cancer pain 3
chills 3
polydipsia 3
motor symptom 3
abdominal cramps 3
bloating 3
skin damage 3
chest pain 3
blepharospasm 3
Gastrointestinal symptoms 3
chorea 3
dry skin 3
regurgitation 3
sore throat 3
hyperoxia 3
chest tightness 3
Hudson 3
arthralgia 3
stigma 3
lightheadedness 3
cerebellar ataxia 2
nasal discharge 2
hunger 2
hypocapnia 2
hyperesthesia 2
frequent urination 2
abnormal gait 2
urinary frequency 2
tingling 2
Involuntary Movement 2
Fluctuation 2
leg cramps 2
leg pain 2
muscle stiffness 2
HSA 2
CSR 2
muscle rigidity 2
dysuria 2
consciousness disturbance 2
Cramping 2
emaciation 2
personality change 2
limb pain 2
abdominal discomfort 2
Postoperative pain 2
Wind 2
polyuria 2
loss of balance 2
rales 2
Deafferentation 2
prostration 2
giddiness 2
giddiness 2
excessive sweating 2
eds 2
tachypnea 2
back pain 2
testicular pain 1
tinnitus 1
hemiplegia 1
dental pain 1
hemoptysis 1
partial seizure 1
Psychiatric symptoms 1
hepatosplenomegaly 1
hot flashes 1
Burning 1
hot flushes 1
hypalgesia 1
stomach pain 1
distraction 1
Increased libido 1
more...
Drug
Donepezil 354
DFP 202
Atropine 170
vitamin E 107
Scopolamine 102
THA 94
CSF 71
ROS 71
Aricept 59
lysine 55
NADH 54
ascorbate 54
caffeine 50
Monit 45
Galanthamine 43
Ethanol 41
Pyridostigmine bromide 40
Glutathione 37
Pralidoxime 35
EDR 35
p75 34
Nephron 33
Gel 32
Pyridostigmine bromide 30
Vitamin E 24
EPA 24
Leaf 24
Dermatol 23
EE2 20
TAK 20
Exelon 20
Asn 19
Reminyl 18
CPT-11 18
Exelon 18
ENT 17
Cardiovasc 17
citric acid 16
IL-2 15
CTX 15
ZnO 15
Albumin 15
ALA 14
Ranitidine 13
Mestinon 13
PCP 13
Portal 13
HCH 13
Spectrum 12
Cognex 12
Biopolymers 12
Fraction 11
CaCl2 11
CaCl2 11
Clonidine 11
Piracetam 11
CaCl2 11
Distigmine bromide 11
Galantamine hydrobromide 11
Kainic acid 11
Tubocurarine 10
TAC 10
Ginseng 10
Ringer's solution 10
PCB 10
TiO2 9
Pilocarpine 9
Serum albumin 9
CoCl2 9
CoCl2 9
Irinotecan 9
Rutin 9
niacin 9
Indomethacin 9
Brij 96 9
MAP 8
MRC 8
DMAA 8
Forskolin 8
Reserpine 8
Fluorescein 8
Senna 8
Senna 8
Histamine 8
Mutagen 8
Capsicum 7
Gallamine 7
ROC 7
Frontal 7
lactose 7
Namenda 7
Triclosan 7
TTC 7
L-tyrosine 6
Phentolamine 6
CPO 6
IFN-gamma 6
Diphenhydramine 6
ABC 6
Ouabain 6
Retinoic acid 6
Papain 6
Pronase 6
Perindopril 6
Phenytoin 6
Cimetidine 6
Cimetidine 6
Bupivacaine 6
Propidium 5
Cisapride 5
Bisacodyl 5
ampicillin 5
Honey 5
OTC 5
Rocuronium 5
Dihydro 5
9-THC 5
Thyroglobulin 5
Azilect 5
Prednisone 5
Prostigmin 5
Atropine sulfate 5
Kenyan 5
Glycyrrhiza 5
Glide 5
Arsenic trioxide 4
Growth hormone 4
Azithromycin 4
G-CSF 4
Adenosine deaminase 4
Xylocaine 4
Rituximab 4
Angiotensin II 4
Idebenone 4
PTC 4
Camp 4
Growth hormone 4
CTX 4
1,8-Cineole 4
ETA 4
CTX 4
ICI 4
Ciclesonide 3
Glutamic acid 3
Marcaine 3
ZnCl2 3
Geranium 3
Sodium nitroprusside 3
NBT 3
Propentofylline 3
Areca 3
Tianeptine 3
Methylene blue 3
Cibacron Blue 3
OTC 3
Nephron 3
Tropicamide 3
Gastro 3
Captopril 3
Safflower 3
more...
Enzyme
acetylcholinesterase 28390
cholinesterase 11108
choline acetyltransferase 1266
catalase 901
superoxide dismutase 791
ATPase 479
glutathione S-transferase 443
alkaline phosphatase 432
lactate dehydrogenase 429
carboxylesterase 416
glutathione peroxidase 376
peroxidase 348
monoamine oxidase 324
alanine aminotransferase 315
aspartate aminotransferase 277
tyrosine hydroxylase 228
paraoxonase 171
glutathione reductase 167
tyrosinase 167
acid phosphatase 161
paraoxonase 150
NADPH-diaphorase 141
trypsin 137
caspase-3 126
choline oxidase 125
succinate dehydrogenase 117
creatine kinase 117
mitogen-activated protein kinase 117
neuropathy target esterase 114
protein kinase 114
gamma-glutamyl transpeptidase 111
diaphorase 111
cytochrome oxidase 104
ACS 101
phospholipase C 99
lipase 95
NQO1 87
glucose-6-phosphate dehydrogenase 86
carbonic anhydrase 85
5'-nucleotidase 85
protein kinase C 84
diaphorase 82
ERK 81
collagenase 74
phosphodiesterase 73
ACE 63
NO synthase 63
lipoxygenase 62
adenylate cyclase 55
chymotrypsin 51
PAM 51
succinic dehydrogenase 50
AST 48
phospholipase A2 47
glutamate dehydrogenase 45
glutamate dehydrogenase 45
glutamate dehydrogenase 45
GSK 44
glutamate decarboxylase 43
adenosine deaminase 43
adenosine deaminase 43
deaminase 43
urease 38
urease 38
aldolase 35
thrombin 35
hexokinase 33
arginase 33
malate dehydrogenase 33
phosphorylase 32
leucine aminopeptidase 31
CD10 31
CYP3A4 31
neuraminidase 29
lysozyme 29
isocitrate dehydrogenase 29
CPR 28
beta-secretase 28
dopamine beta-hydroxylase 28
glucose-6-phosphatase 27
beta-glucuronidase 26
xanthine oxidase 26
hyaluronidase 26
Mg2+-ATPase 26
cholesterol esterase 25
papain 25
hyaluronidase 24
beta-galactosidase 24
alpha-amylase 24
enolase 23
nucleotidase 23
complex I 22
PDE 22
pyruvate kinase 22
pepsin 22
NOS 22
isocitrate dehydrogenase 21
prolyl endopeptidase 20
focal adhesion kinase 19
glucose oxidase 19
caspase-9 18
ceruloplasmin 18
luciferase 18
delta-aminolevulinic acid dehydratase 18
alcohol dehydrogenase 18
glutamine synthetase 18
P-glycoprotein 17
PAH 16
PARP 16
demethylase 16
DFPase 16
alpha-glucosidase 16
AMPK 15
sorbitol dehydrogenase 15
monoacylglycerol lipase 15
renin 15
calcineurin 15
6-phosphogluconate dehydrogenase 14
6-phosphogluconate dehydrogenase 14
PCP 13
aldose reductase 13
citrate synthase 13
thromboplastin 13
phospholipase D 12
glyceraldehyde-3-phosphate dehydrogenase 12
adenylate kinase 12
elastase 12
reverse transcriptase 12
glyceraldehyde-3-phosphate dehydrogenase 12
DOPA decarboxylase 12
tyrosine aminotransferase 12
hexosaminidase 11
proteinase K 11
phosphofructokinase 11
glyceraldehyde-3-phosphate dehydrogenase 11
ornithine decarboxylase 11
RNase 11
RNase 11
phosphoglucomutase 11
glycerol-3-phosphate dehydrogenase 10
flavin-containing monooxygenase 10
CNPase 10
glyceraldehyde-3-phosphate dehydrogenase 10
MEK 10
phosphoinositide 3-kinase 10
UDP-glucuronosyltransferase 10
apyrase 10
glyceraldehyde-3-phosphate dehydrogenase 10
guanylate cyclase 10
transpeptidase 10
glycerol-3-phosphate dehydrogenase 10
proteasome 9
choline kinase 9
lactic acid dehydrogenase 9
PI-PLC 9
lecithin:cholesterol acyltransferase 9
NADH dehydrogenase 9
CD13 9
aspirin esterase 9
cellulase 8
more...
Compound
Dec 1980
water 1861
Clin 840
sodium 682
calcium 664
oxygen 604
DNA 591
ACh 591
glucose 511
phosphate 509
GSH 456
GSH 456
glutamate 406
hydrogen 390
galanthamine 376
acetate 355
nitric oxide 326
ethanol 315
serine 301
iodine 286
bromide 277
salt 268
potassium 262
PAM 260
nitrogen 252
methanol 252
sulfate 248
DPPH 239
silver 222
Physostigmine 222
copper 210
noradrenaline 208
Triton X-100 202
urea 201
ethyl acetate 199
GABA 195
GABA 191
ATP 185
5-HT 181
creatinine 172
zinc 171
Atropine 170
Chlorpyrifos 169
TNF 168
Tacrine 166
galactose 165
His 162
pyridine 159
ammonium 158
iron 150
phosphorus 142
tyrosine 142
arginine 142
DDVP 138
OMPA 130
cadmium 129
cysteine 125
NMDA 124
SDS 121
Rivastigmine 119
gamma-aminobutyric acid 117
cAMP 111
hexane 111
alanine 108
Soman 104
ACS 101
ACS 101
SEE 100
leucine 99
methionine 99
QNB 99
piperidine 97
piperidine 97
AMP 97
CAT 96
MDA 96
CAT 95
CAT 95
Pyridostigmine 94
aluminum 93
phenol 91
mercury 87
MTT 86
H2O2 86
nitrate 85
chloroform 85
Neostigmine 84
acetic acid 82
Neuronal 81
Asp 81
Formal 80
Gly 80
tryptophan 79
lysine 79
DEP 75
Mg2+ 75
Memantine 74
nicotinamide 74
acrylamide 73
tryptophan 73
tryptophan 72
tryptophan 72
Choline 72
EDTA 71
Paraoxon 70
PAM 70
PAM 70
palmitic acid 70
Diazinon 70
Phe 69
EDTA 69
manganese 69
fluorine 68
DDT 68
selenium 68
dichloromethane 67
NADPH 66
NADPH 66
quinoline 65
quinoline 65
TMB-4 63
NH2 62
Pac 62
PEG 61
gallic acid 61
DAD 60
Sarin 59
4-nitrophenyl 59
retinoic acid 57
ammonia 56
Nicotine 56
NADH 54
benzene 54
glutamine 53
Panam 53
acetonitrile 52
acetone 52
caffeine 51
pyrene 51
DMSO 50
STZ 49
TOF 49
aspartic acid 48
formaldehyde 46
HCl 46
aldehyde 46
AMPA 45
proline 45
O,O-diethyl 45
Cereb 43
GPT 43
isoquinoline 43
Carbofuran 42
cobalt 42
Lead 42
nickel 41
CO2 41
glutamic acid 41
formaldehyde 41
GSSG 40
more...