Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.1.53 (sialidase)
2,694 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A method has been developed for the phenotyping of pig apolipoprotein E. It was based on isoelectric focusing of sialidase-treated and delipidated blood plasma followed by immunoblotting. As the first antibody the anti-human apolipoprotein E antibody was used. The genetic polymorphism of pig apolipoprotein E appeared to be controlled by three alleles at one locus. A two-point linkage analysis was performed between certain loci belonging to the halothane linkage group and the APOE locus on material comprising 9 Zlotnicka Spotted boars, 30 Polish Large White sows, and their 160 offspring. A tight linkage between the A1BG and the APOE loci was documented (theta = 0.038).
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PMID:Phenotyping of porcine apolipoprotein E using isoelectric focusing and localization of the APOE gene within the halothane-susceptibility linkage group. 1062 36