Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.1.5 (neuropathy target esterase)
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Human Gene/Protein
NTE 14.9
lysophospholipase 14.9
LYPLA1 protein 14.9
neuropathy target esterase 14.8
PLB/LIP 14.5
KIAA0415 14.3
Lysophospholipase 14.2
PLB1 13.8
Acyl-protein thioesterase 1 13.7
lysophospholipase II 13.6
SPG42 13.5
glycerophosphodiester phosphodiesterase domain containing 5 13.3
LPL1 13.0
PNPLA7 12.9
phospholipase B1 12.8
reticulon 2 12.5
Phospholipase B1 12.5
PLBD1 12.5
Charcot-Leyden crystal protein 12.5
acyl-protein thioesterase 12.5
Neuropathy target esterase 12.5
NPP6 12.4
GDE3 12.1
NPP5 12.1
KIAA1840 11.7
ZFYVE27 11.7
NPP2 11.6
ARHGEF18 11.5
GDPD5 11.5
lysophospholipid acyltransferase 11.5
SPG8 11.5
ASPG 11.4
PLA2G4D 11.4
arylformamidase 11.4
76 kDa protein 11.4
transacylase 11.2
AdPLA 11.2
ABHD4 11.2
DRiP78 11.2
NPP4 11.2
SPG2 11.1
AP4S1 11.1
ERLIN2 11.0
SPG6 11.0
PNPLA8 11.0
intestine-specific homeobox 10.9
hepatocellular carcinoma related protein 1 10.9
alkaline sphingomyelinase 10.8
PLA1 10.8
GDE2 10.8
SPG20 10.7
SPG10 10.7
AP4B1 10.7
KIAA0196 10.6
galectin-13 10.6
SPG3 10.5
LIP4 10.5
DDHD1 10.5
LIP3 10.5
SAP3 10.4
acylglycerol kinase 10.3
ZFYVE26 10.3
LIPH 10.3
3-hydroxyisobutyryl-CoA hydrolase 10.2
NIPA1 10.1
IF3(mt) 10.1
Lysosomal phospholipase A2 10.1
DDHD2 10.0
GDE1 10.0
spartin 10.0
Cholinephosphotransferase 9.9
aldehyde reductase I 9.9
SAP1 9.8
PLB 9.8
REEP1 9.8
insulysin 9.7
CYP2U1 9.7
Troyer syndrome 9.7
SPG15 9.7
SAP2 9.7
more...
Disease
SPG33 12.9
SPG12 12.9
SPG30 12.5
SPG13 12.3
SPG8 12.1
SPG28 11.4
SPG21 11.3
SPG6 11.2
SPG2 11.1
SPG20 11.0
SPG10 11.0
SPG31 11.0
Spastic quadriplegia 11.0
SPG1 10.4
Mucolipidosis 10.1
SPG15 9.7
SPG7 9.5
Disseminated cryptococcosis 9.1
ML III 8.8
NML 8.7
Myrmecia 8.3
SPG11 8.1
Hereditary spastic paraplegia 7.8
spastic paraplegia 7.8
polyneuropathy 7.5
SPG4 7.5
Hodgson 7.4
neuropathy 7.4
Barth syndrome 6.9
Cryptococcus neoformans 6.9
KPC 6.7
Angiostrongylus cantonensis 6.5
urticaria pigmentosa 6.4
protozoan infection 6.4
Legionella 6.3
Pfeiffer 6.1
PAF 6.1
VPI 6.1
Hymenolepis 6.1
MPE 6.0
CP1 6.0
clonorchiasis 6.0
vibriosis 5.9
Weil 5.9
vaginal candidiasis 5.8
SLS 5.8
HES 5.8
Ovary 5.7
motor neuron disease 5.7
sensory neuropathy 5.6
hemoglobinuria 5.6
keratoconjunctivitis 5.4
Haas 5.4
IVA 5.4
roundworm 5.2
multiple disorders 5.2
candidiasis 5.2
PSP 5.1
orf 5.0
cholecystitis 5.0
Ovary 5.0
leukodystrophy 5.0
maple syrup urine disease 5.0
Jensen 4.9
Testes 4.9
legionellosis 4.9
eosinophilia 4.7
skin ulcers 4.6
secondary infection 4.6
autonomic neuropathy 4.5
SDS 4.5
open angle glaucoma 4.5
neuroblastoma 4.4
cryptococcal meningitis 4.4
listeriosis 4.4
neoplastic process 4.3
pancreatic insufficiency 4.3
SAD 4.2
MIP 4.1
HDL2 4.1
more...
Symptom
Cramping 10.2
Behavioral symptoms 8.5
ataxia 5.8
incoordination 5.1
abnormal gait 4.7
tingling 4.5
spasticity 3.8
paresis 3.4
weakness 3.4
numbness 2.5
myalgia 2.2
vertigo 2.1
splenomegaly 1.6
anorexia 1.1
tremor 0.7
respiratory distress 0.6
analgesia 0.1
collapse 0.1
anesthesia -0.9
headache -0.9
pain -2.1
Drug
DFP 10.1
Polysorbate 20 9.0
Pirarubicin 8.3
Lasalocid 7.9
Corn oil 7.6
APM 7.4
Lipidex 7.3
Miltefosine 7.0
CPO 6.6
Liraglutide 6.1
Trifluoperazine 6.1
Papain 5.7
linolenate 5.6
CaCl2 5.4
CaCl2 5.4
CaCl2 5.4
Atropine 4.8
Glycerol 4.7
Serum albumin 4.6
Fluconazole 4.5
Meth 4.5
Vitamin A 4.3
balanced salt solution 4.3
Bayer 4.2
MIL 4.2
Check 3.9
Histamine 3.4
vitamin E 3.3
Gel 3.3
Taxol 3.2
Vitamin E 3.2
PCP 3.0
EE2 2.9
Asn 2.9
nitroglycerin 2.7
CTX 2.4
CTX 2.4
Bifidobacterium 2.3
Indomethacin 2.2
EPA 2.1
MAP 1.9
DNase I 1.8
Ethanol 1.6
CTX 1.5
lysine 1.3
Nephron 0.7
Leaf 0.5
ascorbate 0.4
IFN-gamma 0.0
IL-2 0.0
Dermatol -1.6
Cardiovasc -2.7
Enzyme
neuropathy target esterase 14.9
phospholipase A1 12.2
glycerophosphocholine phosphodiesterase 11.9
lysoplasmalogenase 11.7
lysophosphatidylcholine acyltransferase 11.0
prepilin peptidase 10.4
3-hydroxyisobutyryl-CoA hydrolase 10.3
glycerophosphodiester phosphodiesterase 10.0
lysophospholipase D 9.9
glutaminyl cyclase 9.7
kynurenine formamidase 9.5
acyloxyacyl hydrolase 9.5
galactolipase 9.4
palmitoyl-CoA hydrolase 9.3
acylglycerol kinase 9.2
acyl-ACP synthetase 9.1
phospholipase A2 8.9
nucleotide pyrophosphatase 8.9
palmitoyl-protein thioesterase 8.8
acyl-CoA thioesterase 8.8
lecithin:retinol acyltransferase 8.5
retinyl ester hydrolase 8.5
GPI-specific phospholipase C 8.5
choline kinase 8.4
monoacylglycerol lipase 8.3
lysyl endopeptidase 8.2
carboxylesterase 8.2
APS kinase 8.0
CYP7B1 7.9
lecithin:cholesterol acyltransferase 7.6
glycerophosphate acyltransferase 7.6
cholesterol acyltransferase 7.6
3-isopropylmalate dehydrogenase 7.5
paraoxonase 7.3
phospholipase D 7.1
phosphatidate phosphatase 7.1
GM3 synthase 7.1
phosphocholine cytidylyltransferase 7.1
cholesterol esterase 7.0
pantothenate kinase 6.9
lipase 6.9
acetylcholinesterase 6.9
cholinesterase 6.7
H,K-ATPase 6.6
neutral sphingomyelinase 6.5
Lys4 6.4
paraoxonase 6.4
arylsulfatase 6.2
choline oxidase 6.2
acyl-CoA synthetase 6.2
hyaluronidase 6.2
sucrase-isomaltase 6.1
phospholipase C 6.0
cutinase 5.9
hyaluronidase 5.7
sucrase 5.6
15-hydroxyprostaglandin dehydrogenase 5.6
5'-nucleotidase 5.6
acyl-CoA synthetase 5.5
phosphatidylinositol 4-kinase 5.5
LPL 5.4
fatty acid desaturase 5.4
insulin-degrading enzyme 5.3
alpha-L-fucosidase 5.3
AGT 5.3
sulfatase 5.2
lipoprotein lipase 5.1
diacylglycerol acyltransferase 5.1
asparaginase 5.1
trehalase 5.0
acylase 5.0
endoglycosidase H 5.0
phosphodiesterase 5.0
CYP7A1 4.9
diacylglycerol kinase 4.9
BAL 4.9
nucleotidase 4.9
3-hydroxy-3-methylglutaryl-CoA reductase 4.7
CPT 4.7
15-lipoxygenase 4.7
more...
Compound
C20H34O3 13.9
C20H34O3 13.9
C20H34O3 13.9
n-Butanesulfonyl fluoride 13.9
C20H34O3 13.9
C20H34O3 13.9
C20H34O3 13.9
n-Butanesulfonyl fluoride 13.9
C20H34O3 12.9
Mipafox 12.8
C20H30O2 12.1
TOCP 12.0
C20H30O3 11.9
propyl propionate 11.5
15S-hydroxyeicosatrienoic acid 11.5
benzyl carbamate 11.3
Glycerophosphocholine 11.1
[1,1'-biphenyl]-4-carboxylic acid 10.8
Methidathion 10.8
dipentyl 10.5
2-furylmethyl 10.4
Diisopropyl fluorophosphate 10.3
Cholesteryl oleate 10.3
linoleoyl-CoA 10.3
Cholesteryl oleate 10.2
A-500 10.2
Elon 10.2
Quinalphos 9.9
C16H14O4 9.6
p-Bromophenacyl bromide 9.4
Paraoxon 9.1
PMSF 9.1
phenyl benzoate 9.0
OMPA 9.0
H-69 8.9
Acephate 8.8
Zeranol 8.6
Cepharanthine 8.4
phenylphosphonic acid 8.3
NEE 8.3
Triton WR-1339 8.3
phenylphosphonic acid 8.3
Sarin 8.3
dibutyl 8.2
dibutyl 8.2
dibutyl 8.2
TMB-4 8.2
Sodium deoxycholate 8.2
methyl butyrate 8.1
2-butenal 8.0
Retinyl palmitate 7.9
O,O-diethyl 7.9
Diisopropyl 7.7
Aldicarb 7.7
2-nonanone 7.5
IEA 7.4
CHAPS 7.4
palmitoyl-CoA 7.4
Phosphatidylcholine 7.4
C56 7.3
2-pentanone 7.3
2-pentanone 7.2
2-pentanone 7.2
Clofazimine 7.2
Carbamate 7.2
1,3-propanediamine 6.9
Chlorpyrifos 6.9
MPE 6.9
pentanal 6.9
Sphingomyelin 6.9
Acyl-CoA 6.9
carbamic acid 6.9
pentanal 6.8
S 1 6.8
TAP 6.8
Leupeptin 6.7
2-pyridinol 6.7
2-pyridinol 6.7
Diazinon 6.6
NaAsO2 6.6
more...