Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.1.5 (
neuropathy target esterase
)
1,070
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
NTE
14.9
LYPLA1 protein
14.9
lysophospholipase
14.9
neuropathy target esterase
14.8
PLB/LIP
14.5
KIAA0415
14.3
Lysophospholipase
14.2
PLB1
13.8
Acyl-protein thioesterase 1
13.7
lysophospholipase II
13.6
SPG42
13.5
glycerophosphodiester phosphodiesterase domain containing 5
13.3
LPL1
13.0
PNPLA7
12.9
phospholipase B1
12.8
Phospholipase B1
12.5
reticulon 2
12.5
PLBD1
12.5
Charcot-Leyden crystal protein
12.5
acyl-protein thioesterase
12.5
Neuropathy target esterase
12.5
NPP6
12.4
GDE3
12.1
NPP5
12.1
ZFYVE27
11.7
KIAA1840
11.7
NPP2
11.6
GDPD5
11.5
ARHGEF18
11.5
lysophospholipid acyltransferase
11.5
SPG8
11.5
PLA2G4D
11.4
ASPG
11.4
arylformamidase
11.4
76 kDa protein
11.4
transacylase
11.2
AdPLA
11.2
ABHD4
11.2
NPP4
11.2
DRiP78
11.2
SPG2
11.1
AP4S1
11.1
ERLIN2
11.0
SPG6
11.0
PNPLA8
11.0
intestine-specific homeobox
10.9
hepatocellular carcinoma related protein 1
10.9
PLA1
10.8
alkaline sphingomyelinase
10.8
GDE2
10.8
SPG20
10.7
SPG10
10.7
AP4B1
10.7
KIAA0196
10.6
galectin-13
10.6
DDHD1
10.5
LIP4
10.5
SPG3
10.5
LIP3
10.5
SAP3
10.4
ZFYVE26
10.3
acylglycerol kinase
10.3
LIPH
10.3
3-hydroxyisobutyryl-CoA hydrolase
10.2
NIPA1
10.1
Lysosomal phospholipase A2
10.1
IF3(mt)
10.1
GDE1
10.0
DDHD2
10.0
spartin
10.0
aldehyde reductase I
9.9
Cholinephosphotransferase
9.9
SAP1
9.8
PLB
9.8
REEP1
9.8
insulysin
9.7
CYP2U1
9.7
Troyer syndrome
9.7
SAP2
9.7
SPG15
9.7
calcium-independent phospholipase A2
9.6
Autotaxin
9.6
glutaminyl cyclase
9.6
ABHD12
9.6
serine hydrolase
9.5
acyloxyacyl hydrolase
9.5
Dyskerin
9.3
HSP-60
9.3
KIF5A
9.3
RCE1
9.2
Ca2+-dependent phospholipase A2
9.2
UEV1A
9.2
ATL1
9.1
SPG7
9.1
BSCL2
9.1
phospholipase
9.1
SPG3A
9.1
PS20
9.0
diglyceride kinase
9.0
MMS2
9.0
sphingomyelin phosphodiesterase
9.0
Phospholipase A2
9.0
stem cell growth factor
9.0
ABHD6
8.9
fatty acid hydroxylase
8.9
cholesterol esterase
8.9
GPE
8.9
pancreatic cholesterol esterase
8.8
nSMase
8.8
cytosolic phospholipase A2
8.8
Carboxylesterase
8.7
cPLA2
8.7
pancreatic lipase-related protein 2
8.7
SLC16A2
8.7
NMT1
8.6
phospholipase A2
8.6
NPP1
8.6
mucolipin 1
8.6
neutral ceramidase
8.5
small GTP binding protein
8.5
LPCAT1
8.5
SPAST
8.5
platelet-activating factor acetylhydrolase
8.5
LPA3
8.5
PTE
8.5
NAPE-PLD
8.5
carboxylesterase
8.4
LPAR1
8.4
Silver syndrome
8.4
monoacylglycerol lipase
8.3
KIF1A
8.3
MYOC
8.3
PAF acetylhydrolase
8.3
alanine-glyoxylate aminotransferase
8.2
CCL15
8.2
lysophosphatidic acid receptor
8.2
Cytosolic phospholipase A2
8.2
HAK
8.1
SPG11
8.1
PPT1
8.1
UMP-CMP kinase
8.0
serine protease 1
8.0
fatty aldehyde dehydrogenase
8.0
cholinephosphotransferase
8.0
eosinophil major basic protein
8.0
110 kDa protein
8.0
palmitoyl-CoA hydrolase
8.0
arylesterase
7.9
CYP7B1
7.9
pancreatic phospholipase A2
7.9
Cx47
7.9
esterase
7.9
annexin A6
7.8
choline kinase
7.7
laminin-binding protein
7.7
ADP-ribosylation factor 1
7.7
GIT1
7.7
GPR55
7.7
calcium-activated neutral protease
7.7
Phospholipase D
7.7
more...
Disease
SPG12
12.9
SPG33
12.9
SPG30
12.5
SPG13
12.3
SPG8
12.1
SPG28
11.4
SPG21
11.3
SPG6
11.2
SPG2
11.1
SPG20
11.0
SPG31
11.0
SPG10
11.0
Spastic quadriplegia
11.0
SPG1
10.4
Mucolipidosis
10.1
SPG15
9.7
SPG7
9.5
Disseminated cryptococcosis
9.1
ML III
8.8
NML
8.7
Myrmecia
8.3
SPG11
8.1
Hereditary spastic paraplegia
7.8
spastic paraplegia
7.8
polyneuropathy
7.5
SPG4
7.5
Hodgson
7.4
neuropathy
7.4
Barth syndrome
6.9
Cryptococcus neoformans
6.9
KPC
6.7
Angiostrongylus cantonensis
6.5
urticaria pigmentosa
6.4
protozoan infection
6.4
Legionella
6.3
Pfeiffer
6.1
PAF
6.1
VPI
6.1
Hymenolepis
6.1
MPE
6.0
CP1
6.0
clonorchiasis
6.0
vibriosis
5.9
Weil
5.9
vaginal candidiasis
5.8
SLS
5.8
HES
5.8
Ovary
5.7
motor neuron disease
5.7
sensory neuropathy
5.6
hemoglobinuria
5.6
keratoconjunctivitis
5.4
Haas
5.4
IVA
5.4
roundworm
5.2
multiple disorders
5.2
candidiasis
5.2
PSP
5.1
orf
5.0
cholecystitis
5.0
Ovary
5.0
leukodystrophy
5.0
maple syrup urine disease
5.0
Jensen
4.9
Testes
4.9
legionellosis
4.9
eosinophilia
4.7
skin ulcers
4.6
secondary infection
4.6
autonomic neuropathy
4.5
SDS
4.5
open angle glaucoma
4.5
neuroblastoma
4.4
cryptococcal meningitis
4.4
listeriosis
4.4
neoplastic process
4.3
pancreatic insufficiency
4.3
SAD
4.2
MIP
4.1
HDL2
4.1
HDL3
4.1
Fibrillation
4.1
autoimmune hemolytic anemia
4.1
FBS
4.1
CIE
4.0
ichthyosis
3.9
epithelial tumor
3.9
neuritis
3.9
LCA
3.9
Niemann-Pick
3.9
acute tubular necrosis
3.8
ichthyosis
3.7
optic atrophy
3.7
HSP
3.6
blast crisis
3.6
PDE
3.5
spongiform encephalopathy
3.5
acute promyelocytic leukemia
3.5
peripheral neuropathy
3.5
eye disease
3.4
worms
3.4
muscular dystrophy
3.3
invasive cancer
3.3
embryonal carcinoma
3.1
progressive supranuclear palsy
3.1
Wright
3.1
Schistosoma mansoni
3.0
alcoholic fatty liver
3.0
meninges
3.0
Dissociation
3.0
transitional cell carcinoma
2.9
myeloid leukemia
2.9
muscular atrophy
2.9
bronchopulmonary dysplasia
2.9
blindness
2.9
Kawasaki disease
2.8
epididymis
2.8
EBV infection
2.8
meningoencephalitis
2.8
DM1
2.8
borderline personality disorder
2.8
Klebsiella
2.8
brain edema
2.7
neurological disease
2.7
PCA
2.7
MAS
2.7
amyotrophic lateral sclerosis
2.6
pertussis
2.6
Mycoplasma
2.6
respiratory failure
2.6
SCH
2.6
cholera
2.5
lung metastases
2.5
Placenta
2.4
enteritis
2.4
ischemia
2.4
myopathy
2.3
Adhesion
2.3
CTX
2.3
rubella
2.3
myocardial ischemia
2.3
small cell lung cancer
2.2
Mycobacterium
2.2
NOD
2.2
erectile dysfunction
2.1
PCP
2.1
astrocytoma
2.1
chronic pancreatitis
2.0
pheochromocytoma
2.0
fibrosarcoma
2.0
SAR
2.0
Duchenne muscular dystrophy
2.0
rabies
1.9
aspergillosis
1.9
coagulopathy
1.9
anaphylaxis
1.9
fungal infection
1.8
Still
1.8
stomatitis
1.7
mole
1.7
more...
Symptom
Cramping
10.2
Behavioral symptoms
8.5
ataxia
5.8
incoordination
5.1
abnormal gait
4.7
tingling
4.5
spasticity
3.8
paresis
3.4
weakness
3.4
numbness
2.5
myalgia
2.2
vertigo
2.1
splenomegaly
1.6
anorexia
1.1
tremor
0.7
respiratory distress
0.6
analgesia
0.1
collapse
0.1
anesthesia
-0.9
headache
-0.9
pain
-2.1
Drug
DFP
10.1
Polysorbate 20
9.0
Pirarubicin
8.3
Lasalocid
7.9
Corn oil
7.6
APM
7.4
Lipidex
7.3
Miltefosine
7.0
CPO
6.6
Liraglutide
6.1
Trifluoperazine
6.1
Papain
5.7
linolenate
5.6
CaCl2
5.4
CaCl2
5.4
CaCl2
5.4
Atropine
4.8
Glycerol
4.7
Serum albumin
4.6
Fluconazole
4.5
Meth
4.5
Vitamin A
4.3
balanced salt solution
4.3
Bayer
4.2
MIL
4.2
Check
3.9
Histamine
3.4
vitamin E
3.3
Gel
3.3
Taxol
3.2
Vitamin E
3.2
PCP
3.0
EE2
2.9
Asn
2.9
nitroglycerin
2.7
CTX
2.4
CTX
2.4
Bifidobacterium
2.3
Indomethacin
2.2
EPA
2.1
MAP
1.9
DNase I
1.8
Ethanol
1.6
CTX
1.5
lysine
1.3
Nephron
0.7
Leaf
0.5
ascorbate
0.4
IFN-gamma
0.0
IL-2
0.0
Dermatol
-1.6
Cardiovasc
-2.7
Enzyme
neuropathy target esterase
14.9
phospholipase A1
12.2
glycerophosphocholine phosphodiesterase
11.9
lysoplasmalogenase
11.7
lysophosphatidylcholine acyltransferase
11.0
prepilin peptidase
10.4
3-hydroxyisobutyryl-CoA hydrolase
10.3
glycerophosphodiester phosphodiesterase
10.0
lysophospholipase D
9.9
glutaminyl cyclase
9.7
kynurenine formamidase
9.5
acyloxyacyl hydrolase
9.5
galactolipase
9.4
palmitoyl-CoA hydrolase
9.3
acylglycerol kinase
9.2
acyl-ACP synthetase
9.1
phospholipase A2
8.9
nucleotide pyrophosphatase
8.9
palmitoyl-protein thioesterase
8.8
acyl-CoA thioesterase
8.8
lecithin:retinol acyltransferase
8.5
retinyl ester hydrolase
8.5
GPI-specific phospholipase C
8.5
choline kinase
8.4
monoacylglycerol lipase
8.3
lysyl endopeptidase
8.2
carboxylesterase
8.2
APS kinase
8.0
CYP7B1
7.9
lecithin:cholesterol acyltransferase
7.6
glycerophosphate acyltransferase
7.6
cholesterol acyltransferase
7.6
3-isopropylmalate dehydrogenase
7.5
paraoxonase
7.3
phospholipase D
7.1
phosphatidate phosphatase
7.1
GM3 synthase
7.1
phosphocholine cytidylyltransferase
7.1
cholesterol esterase
7.0
pantothenate kinase
6.9
lipase
6.9
acetylcholinesterase
6.9
cholinesterase
6.7
H,K-ATPase
6.6
neutral sphingomyelinase
6.5
Lys4
6.4
paraoxonase
6.4
arylsulfatase
6.2
choline oxidase
6.2
acyl-CoA synthetase
6.2
hyaluronidase
6.2
sucrase-isomaltase
6.1
phospholipase C
6.0
cutinase
5.9
hyaluronidase
5.7
sucrase
5.6
15-hydroxyprostaglandin dehydrogenase
5.6
5'-nucleotidase
5.6
acyl-CoA synthetase
5.5
phosphatidylinositol 4-kinase
5.5
LPL
5.4
fatty acid desaturase
5.4
insulin-degrading enzyme
5.3
alpha-L-fucosidase
5.3
AGT
5.3
sulfatase
5.2
lipoprotein lipase
5.1
diacylglycerol acyltransferase
5.1
asparaginase
5.1
trehalase
5.0
acylase
5.0
endoglycosidase H
5.0
phosphodiesterase
5.0
CYP7A1
4.9
diacylglycerol kinase
4.9
BAL
4.9
nucleotidase
4.9
3-hydroxy-3-methylglutaryl-CoA reductase
4.7
CPT
4.7
15-lipoxygenase
4.7
papain
4.5
proteinase K
4.5
acid phosphatase
4.4
laccase
4.3
leucine aminopeptidase
4.2
MIP
4.2
lipoxygenase
4.1
aconitase
4.1
chymotrypsin
4.0
thermolysin
4.0
lactase
3.8
chaperonin
3.8
phosphoglycerate kinase
3.8
subtilisin
3.8
matrix metalloproteinase 2
3.7
urease
3.6
invertase
3.6
urease
3.6
SPC
3.5
alpha-amylase
3.5
beta-glucosidase
3.4
glucokinase
3.4
trypsin
3.3
tyrosinase
3.3
kallikrein
3.3
CPT
3.2
ricin
3.2
beta-glucosidase
3.2
thrombin
3.2
HSD
3.1
PDE
3.0
PCP
3.0
phosphofructokinase
3.0
neutrophil elastase
2.9
alpha-glucosidase
2.8
aldehyde dehydrogenase
2.8
aldehyde dehydrogenase
2.8
glutathione peroxidase
2.8
aldehyde dehydrogenase
2.7
CPT
2.7
alcohol dehydrogenase
2.7
transcriptase
2.7
glutathione reductase
2.6
glutamine synthetase
2.6
ceruloplasmin
2.6
deaminase
2.5
aldehyde dehydrogenase
2.5
hexokinase
2.5
lactate dehydrogenase
2.3
creatine kinase
2.2
choline acetyltransferase
2.2
aldehyde dehydrogenase
2.2
protein kinase C
2.1
ATP synthase
2.1
proteasome
2.0
MAP
2.0
DNase
2.0
glucose-6-phosphate dehydrogenase
1.9
succinate dehydrogenase
1.9
RNase
1.9
calcineurin
1.8
RNase
1.7
plasmin
1.7
elastase
1.7
ACE
1.7
peroxidase
1.7
adenylate cyclase
1.6
CD10
1.6
monoamine oxidase
1.5
ATPase
1.5
phosphatidylinositol 3-kinase
1.4
glutathione S-transferase
1.4
tissue plasminogen activator
1.4
alkaline phosphatase
1.3
AMPK
1.3
thromboplastin
1.2
neuraminidase
1.0
beta-galactosidase
1.0
superoxide dismutase
1.0
RNA polymerase
0.8
more...
Compound
C20H34O3
13.9
n-Butanesulfonyl fluoride
13.9
n-Butanesulfonyl fluoride
13.9
C20H34O3
13.9
C20H34O3
13.9
C20H34O3
13.9
C20H34O3
13.9
C20H34O3
13.9
C20H34O3
12.9
Mipafox
12.8
C20H30O2
12.1
TOCP
12.0
C20H30O3
11.9
propyl propionate
11.5
15S-hydroxyeicosatrienoic acid
11.5
benzyl carbamate
11.3
Glycerophosphocholine
11.1
Methidathion
10.8
[1,1'-biphenyl]-4-carboxylic acid
10.8
dipentyl
10.5
2-furylmethyl
10.4
Diisopropyl fluorophosphate
10.3
Cholesteryl oleate
10.3
linoleoyl-CoA
10.3
A-500
10.2
Elon
10.2
Cholesteryl oleate
10.2
Quinalphos
9.9
C16H14O4
9.6
p-Bromophenacyl bromide
9.4
Paraoxon
9.1
PMSF
9.1
phenyl benzoate
9.0
OMPA
9.0
H-69
8.9
Acephate
8.8
Zeranol
8.6
Cepharanthine
8.4
phenylphosphonic acid
8.3
NEE
8.3
Triton WR-1339
8.3
phenylphosphonic acid
8.3
Sarin
8.3
dibutyl
8.2
dibutyl
8.2
TMB-4
8.2
dibutyl
8.2
Sodium deoxycholate
8.2
methyl butyrate
8.1
2-butenal
8.0
Retinyl palmitate
7.9
O,O-diethyl
7.9
Diisopropyl
7.7
Aldicarb
7.7
2-nonanone
7.5
IEA
7.4
CHAPS
7.4
palmitoyl-CoA
7.4
Phosphatidylcholine
7.4
C56
7.3
2-pentanone
7.3
2-pentanone
7.2
2-pentanone
7.2
Clofazimine
7.2
Carbamate
7.2
1,3-propanediamine
6.9
MPE
6.9
pentanal
6.9
Chlorpyrifos
6.9
Sphingomyelin
6.9
Acyl-CoA
6.9
carbamic acid
6.9
pentanal
6.8
S 1
6.8
TAP
6.8
Leupeptin
6.7
2-pyridinol
6.7
2-pyridinol
6.7
Diazinon
6.6
NaAsO2
6.6
2-pyridinol
6.5
Cholic acid
6.5
methylcyclohexane
6.5
CoA
6.4
PLA
6.4
Leupeptin
6.4
decanal
6.3
hexadecyl
6.3
decanal
6.3
Ether
6.1
Arachidonic acid
6.1
Cystine
6.1
Ether
6.1
octanal
6.1
octanal
6.1
Trifluoperazine
6.1
Triton X-100
6.1
LPC
6.0
D-600
6.0
TPP
6.0
phenylacetaldehyde
5.9
butyl acetate
5.9
Coomassie Blue
5.9
Antimycin
5.9
PIN
5.9
octanoic acid
5.8
octanoic acid
5.8
octanoic acid
5.8
Coenzyme A
5.8
Quinacrine
5.8
octanoic acid
5.8
Triiodothyronine
5.7
APH
5.7
octanoic acid
5.7
DEAE
5.7
DCP
5.6
butanal
5.6
palmitic acid
5.6
PAM
5.5
DPA
5.5
myristic acid
5.5
Phorbol 12-myristate 13-acetate
5.5
Cystine
5.5
Brilliant Blue
5.4
TMEDA
5.4
octyl
5.4
octyl
5.4
octyl
5.4
DDVP
5.4
CaCl2
5.4
4-nitrophenyl
5.4
2,5-hexanedione
5.4
myristic acid
5.3
ethanesulfonic acid
5.3
ethanesulfonic acid
5.3
heptose
5.2
heptose
5.2
heptose
5.2
1-butanol
5.2
palmitic acid
5.2
2-naphthyl
5.1
phosphoserine
5.1
2-butanone
5.0
Chloroquine
5.0
Chloroquine
5.0
DCP
5.0
SAD
5.0
NEM
4.9
MgCl2
4.9
DEP
4.9
PSP
4.9
serine
4.8
Atropine
4.8
L-T3
4.7
cyclohexane
4.7
Dipyridamole
4.7
Dipyridamole
4.7
Dipyridamole
4.7
Dipyridamole
4.7
FMLP
4.7
more...