Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.1.5 (
neuropathy target esterase
)
1,070
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Phospholipid peroxidation and the activities of phospholipase A, acyl
Coenzyme A
:lysophospholipid acyltransferase and
lysophospholipase
were measured in isolated bovine rod outer segments (ROS) that were incubated in the presence or absence of the added antioxidants, vitamin E and dithiothreitol (DTT), and additionally in light or dark. DTT and vitamin E significantly inhibit both lipid peroxidation and the enzyme activities. These results suggest that one function of the enzymes for molecular replacement of fatty acids in ROS, is removal of peroxidized fatty acids and thus protection of the membrane phospholipids and proteins from further oxidative damage.
...
PMID:Effects of the antioxidants dithiothreitol and vitamin E on phospholipid metabolism in isolated rod outer segments. 206 29
