Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.1.5 (neuropathy target esterase)
1,070 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Marked increases in phospholipase B activity were measured in spleen homogenates and sera of CD-1 mice given a primary infection of Plasmodium yoelii. The rise in enzyme activity paralleled parasitemia and splenomegaly, all reaching maximum values 14 days after infection. Maximum enzyme activity and splenomegaly were noted 5 days after challenge in mice given a secondary infection indicating an anamnesticlike response following a subsequent contact with the infecting parasite. These observations represent a new finding of this enzyme activity in a protozoan infection.
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PMID:Elevated levels of phospholipase B in mice infected and challenged with Plasmodium yoelii. 713 Nov 82