Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.1.34 (lipoprotein lipase)
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Human Gene/Protein
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 12.1
glycerol-3-phosphate dehydrogenase 1 (soluble) 12.1
lipoprotein lipase 12.1
lipase maturation factor 1 11.8
LPL protein 11.4
hepatic lipase 11.2
LMF1 11.2
GPIHBP1 11.2
apolipoprotein C-II 11.2
KLHL18 11.1
GLTPD2 11.1
cholinergic receptor, nicotinic, delta polypeptide 11.1
GALNT16 11.1
abhydrolase domain containing 4 11.1
ANGPTL3 protein 11.1
long-chain acyl-CoA synthetase 5 11.1
PLPL 11.1
Lipase H 11.1
HTGL 11.0
apolipoprotein CII 10.9
RHC 10.9
Diacylglycerol lipase 10.9
TSARG7 10.8
ANGPTL3 10.6
steroid 11-beta-hydroxylase 10.6
fatty acid amide hydrolase 2 10.6
DEP domain containing 4 10.6
Lipoprotein lipase 10.5
Angiopoietin-like 3 10.4
endothelial lipase 10.4
glycerol-3-phosphate acyltransferase, mitochondrial 10.3
acyl-CoA thioesterase 2 10.1
HLAL 10.1
N-acyl phosphatidylethanolamine phospholipase D 10.1
cAMP responsive element binding protein 3-like 3 10.1
Triacylglycerol lipase 10.0
OSBP-related protein 8 9.8
DELTA1 9.8
Retinoid-related orphan receptor gamma 9.8
GTP binding protein overexpressed in skeletal muscle 9.8
monoacylglycerol lipase 9.8
LPL 9.7
VGL 9.6
ANGPTL4 9.6
acyl-CoA:cholesterol acyltransferase-2 9.6
SCYL2 9.6
APOL2 9.6
ADP-ribosylation factor-related protein 1 9.6
apolipoprotein B48 receptor 9.6
GPR55 protein 9.6
apolipoprotein A-V 9.5
Apolipoprotein C-III 9.5
APC2 protein 9.3
IL2-R alpha 9.3
CREB3L3 9.3
LDLB 9.3
DAGLB 9.3
LDHL 9.3
APOC2 9.3
apo CIII 9.3
apolipoprotein A5 9.3
fatty acid transport protein 1 9.2
adenylate kinase 3 9.1
NECAP1 9.1
alpha-2-macroglobulin receptor 9.1
NAPEPLD 9.1
LIPG 9.1
beta4Gal-T1 9.1
lipase H 9.1
LPL1 9.0
APOC3 9.0
TBL3 9.0
adipsin 8.9
APOA5 8.9
HDL2 8.8
VAX2 8.8
KIF9 8.8
RNA binding motif protein 8.8
FAAH1 8.8
Suppressor of cytokine signaling-2 8.8
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Disease
hyperchylomicronemia 10.9
Chylomicronemia syndrome 10.6
FHBL2 10.3
hyperheparinemia 9.6
familial hypertriglyceridemia 9.4
toxic amblyopia 9.1
Type III hyperlipoproteinemia 9.1
Type V hyperlipoproteinemia 9.0
Secondary hyperlipidemia 9.0
HDL2 8.8
Familial combined hyperlipidemia 8.8
Lipemia retinalis 8.8
hypoalphalipoproteinemia 8.5
HDL3 8.5
Combined hyperlipidemia 8.3
Eruptive xanthomas 8.3
Aromatase deficiency 8.3
hyperlipoproteinemia 8.3
lipoprotein disorder 8.1
hypolipoproteinemia 7.9
HDL1 7.8
lipoproteinemia 7.6
hypobetalipoproteinemia 7.5
Secretory diarrhea 7.4
Hypothalamic obesity 7.3
lipid disorder 7.3
APOA1 7.3
xanthomatosis 7.1
hyperlipidemia 7.0
HLP 7.0
Behr 6.9
familial hyperlipidemia 6.9
C syndrome 6.6
LDLR 6.5
LCAT deficiency 6.5
chylomicron retention disease 6.4
Cardiovascular morbidity 6.4
cholesterolemia 6.4
cholesterol ester storage disease 6.4
moderate obesity 6.4
Retinal damage 6.3
Tangier disease 6.3
Factor V Leiden mutation 6.2
cystic acne 6.0
dyslipidemia 6.0
SCA17 5.9
hyperinsulinemia 5.7
GSD I 5.7
Medulla 5.6
atherosclerotic cardiovascular disease 5.6
LIP 5.5
FED 5.5
syndrome X 5.4
metabolic syndrome X 5.3
Familial hypercholesterolemia 5.3
hypercholesterolemia 5.2
APOB 5.2
PLAT 5.1
atherosclerosis 5.0
abdominal obesity 5.0
nephrosis 5.0
Weber-Christian disease 5.0
avitaminosis 5.0
postmaturity 4.9
arteriosclerosis 4.9
orphan disease 4.9
fatty liver 4.9
Diabetes and Pregnancy 4.9
STY 4.8
pancreatitis 4.8
acute pancreatitis 4.8
lipodystrophy 4.7
Diabetic peripheral neuropathy 4.7
PHP 4.7
overnutrition 4.7
coronary heart disease 4.7
LPI 4.6
hyperviscosity syndrome 4.6
SCD 4.6
Gram-negative bacteremia 4.6
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Symptom
RNA marker 7.6
ketonuria 5.4
cachexia 5.0
Decreased activity 4.7
Cushingoid 4.4
Cushingoid 4.3
hyperemesis 3.9
Physical findings 3.8
hepatosplenomegaly 3.7
hypoproteinemia 3.6
starvation 3.2
emaciation 3.1
hepatomegaly 2.8
overweight 2.7
exertional angina 2.6
acute abdominal pain 2.2
dry skin 2.2
Hudson 2.1
abnormal gait 2.0
anorexia 2.0
Wind 1.8
bitter taste 1.7
splenomegaly 1.7
abdominal pain 1.6
HSA 1.6
myalgia 1.5
hypocapnia 1.4
abdominal discomfort 1.4
polydipsia 1.0
masculinization 0.8
exhaustion 0.7
agitation 0.6
acute abdomen 0.6
flushing 0.5
epigastric pain 0.4
memory loss 0.3
analgesia 0.2
acute stress -0.0
nausea and vomiting -0.1
acidity -0.2
hunger -0.3
lethargy -0.3
hypothermia -0.3
respiratory distress -0.5
tinnitus -0.5
vertigo -0.7
arthralgia -0.7
fatigue -0.7
spasm -0.7
diarrhea -0.9
pain -0.9
chest pain -0.9
constipation -1.2
Ill -1.3
sleepiness -1.5
seizures -1.6
dyspnea -1.6
vomiting -1.8
angina -2.2
nausea -2.4
anesthesia -3.0
weakness -3.1
headache -3.6
Drug
Ibrolipim 12.1
Clinofibrate 9.6
Advexin 8.7
MK-733 8.3
Meridia 8.1
Niceritrol 7.9
Oxfenicine 7.8
Gemfibrozil 7.7
Lipitor 7.4
Bezafibrate 7.0
Orlistat 7.0
Lipitor 6.9
Lipitor 6.9
Cimaterol 6.8
Ponalrestat 6.8
Insulin aspart 6.6
Corn oil 6.5
Lard 6.4
Sodium carbonate 6.4
Sodium ascorbate 6.4
Tallow 6.3
Liposyn 6.3
Elvitegravir 6.2
Protamine sulfate 6.2
Fragmin 6.2
Colestipol 6.1
Rosiglitazone 5.9
Naftidrofuryl 5.9
CET 5.8
Clofibrate 5.6
Malonaldehyde 5.5
Coconut oil 5.5
Troglitazone 5.4
Trapidil 5.3
Estracyt 5.3
Estracyt 5.1
Antithrombin III 5.1
LMWH 5.1
Cilostazol 5.0
ID2 5.0
Pregnenolone 5.0
Chlorate 5.0
Myricetin 4.9
Soybean oil 4.9
Trental 4.9
IL-11 4.8
Monosodium glutamate 4.8
Rimonabant 4.8
Nadolol 4.8
EPL 4.7
EML 4.7
Bexarotene 4.7
Glycerol 4.7
Dalteparin 4.7
Guar gum 4.6
Lovastatin 4.6
Olive oil 4.5
Lupron 4.5
Simvastatin 4.5
Olmesartan 4.4
Parlodel 4.4
DEX 4.3
Raltegravir 4.3
DFP 4.3
Vitamin E 4.3
niacin 4.3
Fenoterol 4.2
Growth hormone 4.2
Prozac 4.2
Growth hormone 4.2
Asparaginase 4.1
Nebivolol 4.1
Pravastatin 4.1
CER 4.0
Levonorgestrel 4.0
linolenate 3.9
Monensin 3.8
Rutin 3.8
Isotretinoin 3.8
Vitamin A 3.6
more...
Enzyme
lipoprotein lipase 12.1
monoacylglycerol lipase 10.0
LPL 9.7
hormone-sensitive lipase 8.8
lipase 8.2
lecithin:cholesterol acyltransferase 8.2
phospholipase A1 8.0
erythritol kinase 8.0
glycerol-3-phosphate dehydrogenase 7.9
beta-ketoadipate enol-lactone hydrolase 7.9
glycerol-3-phosphate dehydrogenase 7.9
long-chain acyl-coenzyme A dehydrogenase 7.8
diacylglycerol acyltransferase 7.8
cholesterol acyltransferase 7.7
glycerol 3-phosphate dehydrogenase 7.5
retinyl ester hydrolase 7.4
cholesterol esterase 7.4
acyl-CoA synthetase 7.2
acetyl-CoA carboxylase 7.2
SOAT 7.1
diacylglycerol kinase 7.1
glycerol-3-phosphate oxidase 7.0
IMP cyclohydrolase 6.8
acyl-CoA synthetase 6.8
acyloxyacyl hydrolase 6.8
gluconate dehydrogenase 6.7
glycerophosphate acyltransferase 6.7
heparinase 6.6
citrate lyase 6.6
palmitoyl-CoA hydrolase 6.5
1-acylglycerol-3-phosphate O-acyltransferase 6.5
monoacylglycerol acyltransferase 6.5
PGE2-9-ketoreductase 6.5
fatty-acid synthase 6.5
glycerol kinase 6.4
acyl-CoA oxidase 6.4
BAT 6.4
AICAR transformylase 6.3
CPT 6.1
3-hydroxyacyl-CoA dehydrogenase 6.1
HMG-CoA synthase 6.0
phospholipase D 6.0
3-hydroxy-3-methylglutaryl-CoA reductase 6.0
NADPH:quinone oxidoreductase 5.8
citrate cleavage enzyme 5.8
dihydroxyacetone phosphate acyltransferase 5.8
CYP7A1 5.8
GPI-specific phospholipase C 5.8
butyryl-CoA dehydrogenase 5.7
acyl-CoA dehydrogenase 5.7
chondroitin ABC lyase 5.7
proprotein convertase 5.6
polypeptide N-acetylgalactosaminyltransferase 5.6
lactose synthetase 5.6
phospholipase A2 5.6
3-oxoacid CoA-transferase 5.5
phosphatidylinositol phospholipase C 5.5
phosphatidylglycerophosphate synthase 5.5
mannosidase I 5.4
3-hydroxy-3-methylglutaryl coenzyme A reductase 5.4
phosphatidylinositol synthase 5.4
phosphatidate phosphatase 5.4
stem bromelain 5.4
glycerol dehydrogenase 5.3
phosphoenolpyruvate carboxykinase 5.3
phosphoenolpyruvate carboxykinase 5.3
endoglycosidase H 5.3
3-hydroxyacyl-CoA dehydrogenase 5.3
phospholipase C 5.3
sterol carrier protein 5.3
glycerol dehydrogenase 5.3
glucose-6-phosphate dehydrogenase 5.2
ACAT 5.2
phosphoenolpyruvate carboxykinase 5.2
fatty acid elongase 5.1
lysophosphatidylcholine acyltransferase 5.1
neuropathy target esterase 5.1
SRR 5.1
iodothyronine 5'-deiodinase 5.0
glycogenin 5.0
more...
Compound
Phthalazinol 10.6
Vitamin U 9.6
3-furoic acid 9.3
Scopolin 9.0
CE 2 9.0
Triton WR-1339 8.6
Loganic acid 8.6
Diglycerol 8.6
vinyl acrylate 8.2
Triolein 8.2
16-hydroxyhexadecanoic acid 8.1
cyclohexanone oxime 8.0
1-methylanthracene 7.9
TMCA 7.8
2,5-pyrrolidinedione 7.8
MEDA 7.8
2-methylanthracene 7.6
Cholesteryl oleate 7.6
Cholesteryl oleate 7.5
diethyl phosphonate 7.3
Miglitol 7.2
Oil Red O 7.2
6-keto PGE1 7.1
FFA 7.1
Wedelolactone 7.1
Fenofibrate 7.1
Raspberry ketone 7.1
Nicarbazin 7.1
X 14 7.0
Diisopropyl fluorophosphate 7.0
Oil Red 7.0
Oil Red O 7.0
vinyl laurate 6.9
Retinyl palmitate 6.8
Laminariaceae 6.8
Probucol 6.8
13-cis-Retinoic acid 6.7
p-Bromophenacyl bromide 6.7
Conjugated linoleic acid 6.7
methyl laurate 6.7
6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 6.7
LOL 6.7
1-octacosanol 6.6
Succinimide 6.6
Nafoxidine 6.6
Pantethine 6.6
Doxazosin 6.6
C6H12O6 6.5
hexadecanedioic acid 6.5
4,6-dimethylpyrimidine 6.5
Tributyrin 6.5
DPBS 6.4
methyl butyrate 6.4
Heparin 6.3
Propiconazole 6.3
1,2-cyclohexanedione 6.3
AEA 6.3
Desogestrel 6.2
Penbutolol 6.2
Nordihydroguaiaretic acid 6.2
Gum arabic 6.1
Guggulsterone 6.1
Colestipol 6.1
Cryptoxanthin 6.1
EPB 6.0
Glabridin 6.0
Benzbromarone 6.0
Biochanin A 6.0
AEA 6.0
Zingerone 5.9
Propyl gallate 5.9
2-furoic acid 5.8
Triamcinolone 5.8
Phytanic acid 5.8
Acebutolol 5.8
Triton 5.8
1H-pyrrole-2,5-dione 5.7
Clofibrate 5.7
Chlorthalidone 5.7
AA861 5.7
more...