Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.1.34 (lipoprotein lipase)
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Human Gene/Protein
glycerol-3-phosphate dehydrogenase 1 (soluble) 12.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 12.1
lipoprotein lipase 12.1
lipase maturation factor 1 11.8
LPL protein 11.4
hepatic lipase 11.2
LMF1 11.2
GPIHBP1 11.2
apolipoprotein C-II 11.2
KLHL18 11.1
GLTPD2 11.1
long-chain acyl-CoA synthetase 5 11.1
cholinergic receptor, nicotinic, delta polypeptide 11.1
GALNT16 11.1
Lipase H 11.1
ANGPTL3 protein 11.1
PLPL 11.1
abhydrolase domain containing 4 11.1
HTGL 11.0
apolipoprotein CII 10.9
RHC 10.9
Diacylglycerol lipase 10.9
TSARG7 10.8
ANGPTL3 10.6
steroid 11-beta-hydroxylase 10.6
DEP domain containing 4 10.6
fatty acid amide hydrolase 2 10.6
Lipoprotein lipase 10.5
Angiopoietin-like 3 10.4
endothelial lipase 10.4
glycerol-3-phosphate acyltransferase, mitochondrial 10.3
cAMP responsive element binding protein 3-like 3 10.1
N-acyl phosphatidylethanolamine phospholipase D 10.1
acyl-CoA thioesterase 2 10.1
HLAL 10.1
Triacylglycerol lipase 10.0
Retinoid-related orphan receptor gamma 9.8
OSBP-related protein 8 9.8
GTP binding protein overexpressed in skeletal muscle 9.8
DELTA1 9.8
more...
Disease
hyperchylomicronemia 10.9
Chylomicronemia syndrome 10.6
FHBL2 10.3
hyperheparinemia 9.6
familial hypertriglyceridemia 9.4
toxic amblyopia 9.1
Type III hyperlipoproteinemia 9.1
Type V hyperlipoproteinemia 9.0
Secondary hyperlipidemia 9.0
HDL2 8.8
Familial combined hyperlipidemia 8.8
Lipemia retinalis 8.8
hypoalphalipoproteinemia 8.5
HDL3 8.5
Combined hyperlipidemia 8.3
Aromatase deficiency 8.3
Eruptive xanthomas 8.3
hyperlipoproteinemia 8.3
lipoprotein disorder 8.1
hypolipoproteinemia 7.9
HDL1 7.8
lipoproteinemia 7.6
hypobetalipoproteinemia 7.5
Secretory diarrhea 7.4
Hypothalamic obesity 7.3
lipid disorder 7.3
APOA1 7.3
xanthomatosis 7.1
hyperlipidemia 7.0
HLP 7.0
Behr 6.9
familial hyperlipidemia 6.9
C syndrome 6.6
LDLR 6.5
LCAT deficiency 6.5
chylomicron retention disease 6.4
Cardiovascular morbidity 6.4
cholesterolemia 6.4
cholesterol ester storage disease 6.4
moderate obesity 6.4
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Symptom
RNA marker 7.6
ketonuria 5.4
cachexia 5.0
Decreased activity 4.7
Cushingoid 4.4
Cushingoid 4.3
hyperemesis 3.9
Physical findings 3.8
hepatosplenomegaly 3.7
hypoproteinemia 3.6
starvation 3.2
emaciation 3.1
hepatomegaly 2.8
overweight 2.7
exertional angina 2.6
acute abdominal pain 2.2
dry skin 2.2
Hudson 2.1
abnormal gait 2.0
anorexia 2.0
Wind 1.8
bitter taste 1.7
splenomegaly 1.7
abdominal pain 1.6
HSA 1.6
myalgia 1.5
hypocapnia 1.4
abdominal discomfort 1.4
polydipsia 1.0
masculinization 0.8
exhaustion 0.7
agitation 0.6
acute abdomen 0.6
flushing 0.5
epigastric pain 0.4
memory loss 0.3
analgesia 0.2
acute stress -0.0
nausea and vomiting -0.1
acidity -0.2
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Drug
Ibrolipim 12.1
Clinofibrate 9.6
Advexin 8.7
MK-733 8.3
Meridia 8.1
Niceritrol 7.9
Oxfenicine 7.8
Gemfibrozil 7.7
Lipitor 7.4
Bezafibrate 7.0
Orlistat 7.0
Lipitor 6.9
Lipitor 6.9
Ponalrestat 6.8
Cimaterol 6.8
Insulin aspart 6.6
Corn oil 6.5
Sodium carbonate 6.4
Lard 6.4
Sodium ascorbate 6.4
Tallow 6.3
Liposyn 6.3
Elvitegravir 6.2
Protamine sulfate 6.2
Fragmin 6.2
Colestipol 6.1
Rosiglitazone 5.9
Naftidrofuryl 5.9
CET 5.8
Clofibrate 5.6
Malonaldehyde 5.5
Coconut oil 5.5
Troglitazone 5.4
Trapidil 5.3
Estracyt 5.3
Estracyt 5.1
Antithrombin III 5.1
LMWH 5.1
Cilostazol 5.0
ID2 5.0
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Enzyme
lipoprotein lipase 12.1
monoacylglycerol lipase 10.0
LPL 9.7
hormone-sensitive lipase 8.8
lipase 8.2
lecithin:cholesterol acyltransferase 8.2
phospholipase A1 8.0
erythritol kinase 8.0
glycerol-3-phosphate dehydrogenase 7.9
beta-ketoadipate enol-lactone hydrolase 7.9
glycerol-3-phosphate dehydrogenase 7.9
diacylglycerol acyltransferase 7.8
long-chain acyl-coenzyme A dehydrogenase 7.8
cholesterol acyltransferase 7.7
glycerol 3-phosphate dehydrogenase 7.5
retinyl ester hydrolase 7.4
cholesterol esterase 7.4
acyl-CoA synthetase 7.2
acetyl-CoA carboxylase 7.2
SOAT 7.1
diacylglycerol kinase 7.1
glycerol-3-phosphate oxidase 7.0
IMP cyclohydrolase 6.8
acyl-CoA synthetase 6.8
acyloxyacyl hydrolase 6.8
gluconate dehydrogenase 6.7
glycerophosphate acyltransferase 6.7
heparinase 6.6
citrate lyase 6.6
palmitoyl-CoA hydrolase 6.5
1-acylglycerol-3-phosphate O-acyltransferase 6.5
monoacylglycerol acyltransferase 6.5
PGE2-9-ketoreductase 6.5
fatty-acid synthase 6.5
glycerol kinase 6.4
acyl-CoA oxidase 6.4
BAT 6.4
AICAR transformylase 6.3
CPT 6.1
3-hydroxyacyl-CoA dehydrogenase 6.1
more...
Compound
Phthalazinol 10.6
Vitamin U 9.6
3-furoic acid 9.3
Scopolin 9.0
CE 2 9.0
Triton WR-1339 8.6
Diglycerol 8.6
Loganic acid 8.6
vinyl acrylate 8.2
Triolein 8.2
16-hydroxyhexadecanoic acid 8.1
cyclohexanone oxime 8.0
1-methylanthracene 7.9
2,5-pyrrolidinedione 7.8
TMCA 7.8
MEDA 7.8
2-methylanthracene 7.6
Cholesteryl oleate 7.6
Cholesteryl oleate 7.5
diethyl phosphonate 7.3
Miglitol 7.2
Oil Red O 7.2
6-keto PGE1 7.1
FFA 7.1
Wedelolactone 7.1
Fenofibrate 7.1
Nicarbazin 7.1
Raspberry ketone 7.1
X 14 7.0
Diisopropyl fluorophosphate 7.0
Oil Red 7.0
Oil Red O 7.0
vinyl laurate 6.9
Retinyl palmitate 6.8
Laminariaceae 6.8
Probucol 6.8
13-cis-Retinoic acid 6.7
p-Bromophenacyl bromide 6.7
Conjugated linoleic acid 6.7
6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 6.7
more...