Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.1.34 (lipoprotein lipase)
 7,025 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
lipoprotein lipase 6495
insulin 1168
hepatic lipase 839
lipase 655
HDL 624
Sep 504
apolipoprotein 356
Mol 289
Lipoprotein lipase 288
apoE 259
peroxisome proliferator-activated receptor 253
fatty acid synthase 253
LPL 244
leptin 226
epididymal 221
hormone-sensitive lipase 212
peroxisome proliferator-activated receptor gamma 178
apolipoprotein B 177
apolipoprotein E 174
HDL2 170
LDL receptor 163
albumin 153
monoacylglycerol lipase 143
adiponectin 141
apolipoprotein C-II 130
tumor necrosis factor 128
A-I 126
phospholipase A2 123
cholesteryl ester transfer protein 112
aP2 95
RHC 94
acetyl-CoA carboxylase 89
cytokine 86
fatty acid binding protein 80
LPL protein 78
apolipoprotein CII 77
HMG-CoA reductase 77
CD36 76
glycerol-3-phosphate dehydrogenase 75
PPAR 74
A-II 74
pancreatic lipase 68
apolipoprotein A-I 65
reductase 65
endoplasmic reticulum 64
endothelial lipase 63
adipose triglyceride lipase 62
alkaline phosphatase 62
growth hormone 60
ATP 60
glucagon 60
stearoyl-CoA desaturase 59
glucose transporter 58
microsomal 57
glucose-6-phosphate dehydrogenase 56
TNF 56
phospholipase D 55
CB1 54
LCAT 53
low-density lipoprotein receptor 51
serum albumin 51
osteogenic 50
carnitine palmitoyltransferase 50
APOC3 50
adipokine 49
AMP 49
phospholipase 48
cannabinoid receptor 48
AMP-activated protein kinase 48
casein 47
prolactin 45
fatty acid amide hydrolase 45
THP 45
esterase 44
collagen 44
lipoprotein receptor-related protein 44
GPIHBP1 43
osteocalcin 43
insulin receptor 42
lipopolysaccharide 42
cyclooxygenase 42
polypeptide 42
superoxide dismutase 41
interleukin-6 41
thrombin 39
phosphoenolpyruvate carboxykinase 39
proteoglycan 38
diacylglycerol acyltransferase 38
apoB-100 38
ANGPTL4 37
Leptin 37
IL-6 37
GLUT4 37
gamma2 36
uncoupling protein 36
adipsin 35
peroxisome proliferator-activated receptor alpha 35
SDS 34
glucose transporter 4 34
perilipin 33
Lp(a) 33
ANGPTL3 33
low density lipoprotein receptor 33
cardiac muscle 33
sterol regulatory element-binding protein 32
gut 32
Lipase 32
membrane-bound 32
IRS-1 32
EBP 32
alanine aminotransferase 31
CB2 31
fatty acid translocase 31
vascular endothelium 31
glycoprotein 30
uncoupling protein 1 30
Peroxisome proliferator-activated receptor 29
UCP2 29
catalase 29
chronic renal failure 28
collagenase 27
C18 27
dimeric 27
apo CIII 27
long chain 27
IL-1 27
aspartate aminotransferase 27
heparan sulfate proteoglycan 26
VLDL receptor 26
acyl-CoA synthetase 25
peroxisome proliferator activated receptor 25
lipoxygenase 25
hemoglobin 25
glutathione peroxidase 24
UCP3 24
cholesterol esterase 24
thyroid hormone 24
TNF-alpha 24
phospholipid transfer protein 24
tyrosine kinase 23
tumor necrosis factor alpha 23
TNF-a 23
diacylglycerol kinase 23
citrate synthase 22
microsomal triglyceride transfer protein 22
APOA5 22
PLA 22
NEFA 22
carnitine palmitoyltransferase 1 22
LDLR 22
nuclear receptor 22
insulin-like growth factor 22
Apolipoprotein E 22
glucocorticoid receptor 21
PPAR gamma 21
ABCA1 21
Pseudomonas 21
osteopontin 21
IGF-I 21
CPT 21
more...
Disease
atherosclerosis 561
obesity 556
diabetes 477
hyperlipidemia 454
dyslipidemia 190
HDL2 170
type 2 diabetes 165
cardiovascular disease 156
coronary artery disease 134
coronary heart disease 132
HDL3 131
hypertension 128
hypercholesterolemia 126
hyperinsulinemia 125
hyperlipoproteinemia 115
metabolic syndrome 98
cancer 97
pancreatitis 96
fatty liver 90
hyperglycemia 79
cold 75
tumor 74
acute pancreatitis 63
depression 53
hyperchylomicronemia 52
glucose intolerance 51
SEM 50
myocardial infarction 43
arteriosclerosis 37
hepatocellular carcinoma 37
Alzheimer's disease 36
chronic renal failure 36
nephrotic syndrome 35
hypothyroidism 34
SDS 34
vascular disease 33
lipid disorder 27
myocardial ischemia 26
hyperphagia 25
renal disease 25
proteinuria 25
malnutrition 24
stroke 23
sepsis 22
LDLR 22
familial hypertriglyceridemia 22
sepsis 22
type 1 diabetes 22
leukemia 22
plaque 21
atherosclerotic cardiovascular disease 20
abdominal obesity 20
uremia 20
liver disease 20
chronic lymphocytic leukemia 20
pertussis 18
tumor growth 17
cholera 17
osteoporosis 17
heart disease 17
renal failure 16
hyperthyroidism 16
FAS 16
Brown 15
gestational diabetes mellitus 15
cardiomyopathy 15
breast cancer 15
heart failure 15
infectious diseases 14
genetic disorder 14
wasting 14
Familial combined hyperlipidemia 14
essential hypertension 13
lipodystrophy 13
hypoalphalipoproteinemia 13
carcinogenesis 13
chronic lymphocytic leukemia 13
HIV 12
anemia 12
lymphoma 11
ischemia 11
Infection 11
Type III hyperlipoproteinemia 11
nephrosis 11
hypoglycemia 11
diabetic nephropathy 10
melanoma 10
cholesterolemia 10
ABL 10
GSH 10
Evans 9
Tangier disease 9
Placenta 9
APOA1 9
glomerulosclerosis 9
xanthomatosis 9
Cushing's syndrome 9
alcoholic fatty liver 9
hypobetalipoproteinemia 8
metabolic disorder 8
uterus 8
preeclampsia 8
malabsorption 8
Familial hypercholesterolemia 8
carcinoma 8
myopathy 8
sympathomimetic 7
syndrome X 7
alcoholism 7
hyperparathyroidism 7
alcohol abuse 7
schizophrenia 7
Cannabis 7
HDL1 7
sickle cell disease 7
ketosis 6
neuroblastoma 6
lipoproteinemia 6
lung cancer 6
cardiovascular risk factor 6
Leukemia 6
sarcoma 6
adenocarcinoma 6
polycystic ovary syndrome 6
SCD 6
hepatitis C 6
hepatitis 6
prostate cancer 6
acne 6
overnutrition 6
ATM 6
Pancreas 6
colon cancer 6
disinhibition 6
dementia 6
Mycoplasma 6
addiction 6
morbid obesity 6
multiple myeloma 6
systemic lupus erythematosus 6
diabetic ketoacidosis 6
neuropathy 5
Blocking 5
NAME 5
colorectal cancer 5
acromegaly 5
liposarcoma 5
cirrhosis 5
LIP 5
cognitive impairment 5
microalbuminuria 5
HLP 5
glioma 5
chronic disease 5
chronic renal insufficiency 5
acute lymphoblastic leukemia 5
cystic fibrosis 5
gallstones 5
bacterial infection 5
AIN 5
more...
Symptom
starvation 49
cachexia 40
overweight 38
pain 31
abdominal pain 21
hepatosplenomegaly 13
anorexia 12
hepatomegaly 9
splenomegaly 7
diarrhea 7
analgesia 7
fatigue 7
seizures 6
exhaustion 5
ketonuria 5
agitation 4
myalgia 4
respiratory distress 3
hypoproteinemia 3
hypothermia 3
anesthesia 3
Decreased activity 3
acidity 3
chest pain 2
nausea and vomiting 2
HSA 2
acute abdominal pain 2
dyspnea 2
emaciation 2
Wind 2
flushing 2
vomiting 2
arthralgia 1
exertional angina 1
angina 1
hypocapnia 1
polydipsia 1
RNA marker 1
abdominal discomfort 1
nausea 1
tinnitus 1
epigastric pain 1
constipation 1
Physical findings 1
hunger 1
lethargy 1
abnormal gait 1
Hudson 1
acute stress 1
sleepiness 1
vertigo 1
Cushingoid 1
spasm 1
masculinization 1
memory loss 1
dry skin 1
Ill 1
headache 1
bitter taste 1
Cushingoid 1
hyperemesis 1
weakness 1
acute abdomen 1
Drug
Cardiovasc 47
vitamin E 26
Asn 24
lysine 20
niacin 16
Gel 16
EPA 15
Gemfibrozil 15
Vitamin E 14
MAP 13
lactose 13
Glycerol 13
Ethanol 12
CAM 12
Growth hormone 12
Growth hormone 12
Orlistat 11
Rosiglitazone 11
ascorbate 11
EE2 10
Nephron 10
caffeine 9
Indomethacin 9
Simvastatin 8
Bezafibrate 8
NADH 8
Vitamin A 8
Dial 7
Lovastatin 7
IL-11 7
ABC 6
Retinoic acid 6
Albumin 6
Angiotensin II 6
Clofibrate 6
PTH 5
ICI 5
Kenyan 5
DMI 5
Troglitazone 5
IFN-gamma 4
Antithrombin III 4
Fragment 4
DEX 4
Estrogens 4
ETA 4
LMWH 4
Dermatol 4
Glucagon 4
DFP 4
Diurnal 4
Histamine 3
Fragmin 3
Cilostazol 3
Fraction 3
Forskolin 3
CTX 3
Lipitor 3
Corn oil 3
Lipitor 3
DNase I 3
Monit 3
Monensin 3
Lipitor 3
Fructose 3
ROS 3
Pravastatin 3
Norplant 3
CaCl2 3
CaCl2 3
CaCl2 3
Pregnenolone 2
Nephron 2
ADM 2
Liposyn 2
Fluorescein 2
Glutathione 2
Isotretinoin 2
uPA 2
citric acid 2
linolenate 2
ID2 2
Rutin 2
L-tyrosine 2
Myricetin 2
Fluorescein 2
Atenolol 2
CDP 2
MK-733 2
Olive oil 2
Rimonabant 2
GEO 2
CET 2
Levonorgestrel 2
MRC 2
FAD 2
Dalteparin 2
nitroglycerin 2
Adriamycin 2
Protamine sulfate 2
PCB 1
Bexarotene 1
CSF 1
Colestipol 1
Trental 1
Dextrose 1
CTX 1
Amiloride 1
Reserpine 1
Meth 1
ALA 1
-deoxyadenosine 1
Trifluoperazine 1
Trapidil 1
p75 1
ETS 1
Ezetimibe 1
Parlodel 1
Chlorate 1
Nebivolol 1
Paraffin 1
Niceritrol 1
GHRP 1
Hydrochlorothiazide 1
CER 1
Advexin 1
ROC 1
Fenoterol 1
balanced salt solution 1
Naftidrofuryl 1
EPL 1
Meridia 1
Capsicum 1
Sodium carbonate 1
Oxfenicine 1
Amiloride 1
Leaf 1
CVA 1
TAT 1
EPI 1
Guar gum 1
NH3 1
Prozac 1
Malonaldehyde 1
Portal 1
PCP 1
Lard 1
Nadolol 1
Florisil 1
Estracyt 1
Sodium ascorbate 1
Bifidobacterium 1
Monosodium glutamate 1
EML 1
Estracyt 1
Soybean oil 1
Asparaginase 1
Cimaterol 1
CTX 1
Clinofibrate 1
more...
Enzyme
lipoprotein lipase 7025
lipase 1245
LPL 244
hormone-sensitive lipase 212
phospholipase C 161
monoacylglycerol lipase 150
phospholipase A2 150
glycerol-3-phosphate dehydrogenase 93
glycerol-3-phosphate dehydrogenase 93
acetyl-CoA carboxylase 92
cholesterol acyltransferase 92
protein kinase 89
protein kinase C 87
lecithin:cholesterol acyltransferase 78
CPT 70
glucose-6-phosphate dehydrogenase 65
alkaline phosphatase 62
AMP-activated protein kinase 60
phospholipase D 55
superoxide dismutase 50
mitogen-activated protein kinase 44
diacylglycerol acyltransferase 42
alanine aminotransferase 40
phosphoenolpyruvate carboxykinase 38
phosphoenolpyruvate carboxykinase 37
phosphoenolpyruvate carboxykinase 37
thrombin 37
cholesterol esterase 34
catalase 33
luciferase 31
acyl-CoA synthetase 31
AMPK 31
trypsin 30
diacylglycerol kinase 29
acyl-CoA synthetase 28
aspartate aminotransferase 28
heparinase 28
collagenase 28
lipoxygenase 26
glutathione peroxidase 24
phospholipase A1 23
CPT 23
citrate synthase 22
CPT 21
malate dehydrogenase 21
lactate dehydrogenase 20
ERK 20
thromboplastin 19
acyl-CoA oxidase 18
adenylate cyclase 17
peroxidase 17
reverse transcriptase 17
acyl-CoA dehydrogenase 16
3-hydroxy-3-methylglutaryl-CoA reductase 16
endoglycosidase H 16
phosphodiesterase 16
AMPK 15
BAT 15
3-hydroxy-3-methylglutaryl coenzyme A reductase 14
ATPase 14
glycerol kinase 14
tissue plasminogen activator 14
cytochrome oxidase 13
RNase 13
urokinase-type plasminogen activator 13
furin 13
CYP7A1 12
renin 12
phosphofructokinase 12
ACE 12
RNase 12
proprotein convertase 12
MEK 12
succinate dehydrogenase 12
isocitrate dehydrogenase 11
glucokinase 11
glucose-6-phosphatase 11
isocitrate dehydrogenase 11
creatine kinase 11
phosphatidylinositol 3-kinase 10
pyruvate kinase 10
focal adhesion kinase 10
subtilisin 10
3-hydroxyacyl-CoA dehydrogenase 10
cholinesterase 10
CAD 9
CAD 9
glyceraldehyde-3-phosphate dehydrogenase 9
proteasome 9
hexokinase 9
CAD 9
phosphorylase 9
acid phosphatase 8
glyceraldehyde-3-phosphate dehydrogenase 8
paraoxonase 8
carboxylesterase 8
neuropathy target esterase 8
glycerol 3-phosphate dehydrogenase 8
6-phosphogluconate dehydrogenase 8
6-phosphogluconate dehydrogenase 8
pyruvate dehydrogenase 7
neuraminidase 7
HMG-CoA synthase 7
paraoxonase 7
glutathione S-transferase 7
glyceraldehyde-3-phosphate dehydrogenase 7
diamine oxidase 7
glycerophosphate acyltransferase 7
caspase-3 7
acetylcholinesterase 6
hyaluronidase 6
beta-galactosidase 6
adenosine deaminase 6
alpha-glucosidase 6
adenosine deaminase 6
glyceraldehyde-3-phosphate dehydrogenase 6
PDK1 6
3-hydroxyacyl-CoA dehydrogenase 6
ribonuclease 6
proteinase K 6
farnesyltransferase 6
citrate lyase 6
ribonuclease 6
asparaginase 6
glyceraldehyde-3-phosphate dehydrogenase 6
NADPH oxidase 5
chondroitinase 5
chondroitinase 5
glutathione reductase 5
plasmin 5
ACS 5
11beta-hydroxysteroid dehydrogenase 5
acyl-CoA dehydrogenase 5
endonuclease 5
NO synthase 5
12-lipoxygenase 5
15-lipoxygenase 4
pyruvate carboxylase 4
lysozyme 4
tyrosine hydroxylase 4
xanthine oxidase 4
matrix metalloproteinase 2 4
CYP3A4 4
gamma-glutamyl transpeptidase 4
MMP-3 4
ATP synthase 4
pyruvate dehydrogenase 4
pyruvate dehydrogenase 4
GSK 4
RNA polymerase 4
chymotrypsin 4
aldose reductase 4
ricin 4
papain 4
NADPH oxidase 4
HSD 3
AST 3
pepsin 3
guanylate cyclase 3
ACAT 3
more...
Compound
glucose 843
Clin 568
Dec 490
glycerol 350
DNA 248
calcium 197
sulfate 180
water 150
Insulin 143
Heparin 118
sodium 116
acetate 114
CoA 112
phosphate 107
oxygen 75
serine 74
ethanol 74
cAMP 71
salt 68
FFA 65
Cholesterol 64
acetone 60
ATP 60
methionine 59
TNF 56
AMP 52
Triton 52
arginine 51
glutamate 51
leucine 47
His 45
THP 45
THP 45
palmitic acid 43
Cardiol 42
Asp 42
alanine 42
Triton X-100 41
Oil Red O 41
SDS 40
noradrenaline 40
PMA 40
palmitic acid 40
Oil Red O 38
cysteine 37
galactose 35
lysine 35
COS 34
Triton WR-1339 33
tyrosine 30
Gly 29
urea 29
threonine 28
Estrogen 28
retinol 27
Arachidonic acid 27
copper 26
retinoic acid 25
potassium 24
NH2 23
nitric oxide 22
nicotinic acid 22
CO2 22
bromide 22
nitrogen 22
CPT 21
CPT 21
Estrogen 20
Phe 20
stearic acid 20
creatinine 20
hexane 19
nicotinic acid 19
AEA 18
Fenofibrate 18
EDTA 18
EDTA 18
Phosphatidylcholine 17
sodium chloride 17
ADP 17
prostacyclin 17
STZ 16
stearic acid 16
ADP 16
Mg2+ 16
ADP 16
stearic acid 16
Vitamin E 16
tryptophan 16
ammonium 15
L-carnitine 15
Hearts 15
zinc 15
silver 15
nicotinic acid 15
nicotinic acid 15
Ile 14
EPA 14
Dexamethasone 14
AEA 14
Adrenal 14
tryptophan 13
glutamine 13
tryptophan 13
NADPH 13
NADPH 13
phosphorus 13
tryptophan 13
Hearts 13
Cortisol 13
MTT 12
Conjugated linoleic acid 12
Propranolol 12
Estradiol 12
acetyl-CoA 12
glutamic acid 12
GSH 12
GSH 12
Propranolol 12
DEAE 12
acetic acid 11
GTP 11
Heparan sulfate 11
Yellow 11
aspartic acid 11
methanol 11
alloxan 11
NADP 11
Progesterone 11
asparagine 11
PGE2 11
acrylamide 11
GABA 10
GABA 10
thioglycollate 10
Nordihydroguaiaretic acid 10
Phosphatidylinositol 10
aspartic acid 10
Probucol 10
TCA 10
DHA 10
aspartic acid 10
Oleic acid 10
DHA 10
aspartic acid 10
pyrene 10
hydrogen 9
ASA 9
BRL 9
Indomethacin 9
cGMP 9
HMG-CoA 9
PLA 9
caffeine 9
Tris 9
iodine 9
Optimal 9
HCl 9
DHA 9
Tris 9
more...