Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.7.7 (
DNA polymerase
)
17,007
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
DNA polymerase
11982
DNA polymerase alpha
1828
Mol
1503
Sep
1145
DNA polymerase beta
1127
pol
1124
Pol
915
ATP
607
endonuclease
589
proliferating cell nuclear antigen
530
thymus
475
helicase
466
polypeptide
427
DNA ligase
349
thymidine kinase
341
RNase H
297
Gen
296
DNA polymerase gamma
291
3'-5' exonuclease
277
DNA polymerase delta
248
DNA primase
227
Polymerase
196
p53
191
DNA-dependent DNA polymerase
188
ATPase
179
mer
169
NMR
155
deoxyribonuclease
155
single-stranded DNA-binding protein
142
DNA helicase
139
ribonucleotide reductase
135
surface antigen
132
TdT
125
interferon
124
single-stranded DNA binding protein
121
telomeric
118
nucleotide pyrophosphatase
115
DNA-binding protein
114
RNase
101
DNase
101
DNA binding protein
100
tRNA
99
ADP
97
fused
96
DNA polymerase-alpha
96
histone
95
TTP
95
alpha, beta
94
glycoprotein
94
ara
93
DNase I
92
replication factor C
89
SDS
88
CTP
87
POLG
79
topoisomerase I
78
thioredoxin
77
DNA ligase I
76
GTP
74
XRCC1
74
RNA-directed DNA polymerase
71
A-T
70
lymphoid
69
dihydrofolate reductase
67
alkaline phosphatase
66
E.coli
66
DNA gyrase
66
dimeric
65
phosphorylating
65
phosphatase
65
flap endonuclease 1
63
RPA
61
AMP
60
cyclin
59
Pseudomonas
58
Poly
57
RNA polymerase II
56
gene 4
54
p21
54
thymidylate synthase
53
serum albumin
52
SSB
52
uracil-DNA glycosylase
52
poly(ADP-ribose) polymerase
52
ACS
50
kit
50
PARP
50
DNA ligase III
49
RFC)
49
RNA polymerase I
47
ubiquitin
47
p66
47
Chk1
47
integrase
46
DNA polymerase eta
45
deoxynucleotidyltransferase
44
Proliferating cell nuclear antigen
43
NTP
40
p180
40
APE1
39
Cdc45
39
DNA repair enzyme
39
DNA topoisomerase
39
xeroderma pigmentosum variant
39
ATR
38
beta-polymerase
38
reductase
37
REV3
36
p68
35
insulin
34
ORF
34
unknown function
34
DNA-directed DNA polymerase
33
REV1
33
thymidylate synthetase
33
XPV
33
PolB
33
MSH2
33
c-myc
32
Met
32
cyclin A
32
deoxyribonuclease I
32
IFN
32
beta-globin
31
DNA polymerase lambda
31
p51
31
deoxycytidine kinase
31
p58
30
K12
30
endonuclease III
30
p12
30
ATM
30
core protein
29
DNA topoisomerase I
29
polynucleotide ligase
29
nuclear protein
29
RFC
29
DNA-binding domain
29
peroxidase
29
cryptic
29
FEN1
29
BRCA1
28
cytokine
28
thymidylate kinase
28
Sp1
28
Ki-67
28
NAD
28
POLQ
27
glutathione S-transferase
27
threonine
27
ribonucleoprotein
27
ras
26
CD4
26
caspase-3
26
DNA polymerase zeta
26
SOD
26
hinge
26
OGG1
26
lipopolysaccharide
26
interacting protein
25
more...
Disease
cancer
1037
herpes simplex
684
tumor
617
HIV
522
hepatitis B
514
cytomegalovirus
417
immunodeficiency
384
leukemia
334
Epstein
215
carcinogenesis
212
myeloblastosis
208
chronic hepatitis
164
AIDS
163
hepatitis
161
herpes
148
hepatocellular carcinoma
139
carcinoma
136
virus infection
126
plaque
115
vaccinia
115
varicella
110
breast cancer
97
TTP
95
TTP
95
infectious diseases
94
sarcoma
90
SDS
88
lymphoma
83
tumorigenesis
79
cold
79
xeroderma pigmentosum
79
Mycobacterium
74
Infection
68
colorectal cancer
62
chronic active hepatitis
57
Rous sarcoma
55
acute myeloid leukemia
50
tuberculosis
49
melanoma
48
cirrhosis
47
ATM
46
anemia
43
Kaposi's sarcoma
42
Adenovirus
42
viremia
37
multiple myeloma
37
encephalitis
36
lung cancer
36
African swine fever
36
squamous cell carcinoma
36
skin cancer
35
tumor growth
35
hepatitis C
34
mammary tumor
34
influenza
33
neuropathy
33
acute lymphoblastic leukemia
33
adenocarcinoma
33
parvovirus
32
CEM
31
acute hepatitis
31
myopathy
30
Alpers
30
colon cancer
29
tumor progression
29
liver disease
29
retinoblastoma
28
ovarian cancer
28
HSV infection
27
neuroblastoma
27
malaria
26
WRN
26
lymphoblastic leukemia
26
MCF
26
lactic acidosis
24
mole
24
BLM
24
Alzheimer's disease
23
chronic myeloid leukemia
23
Leukemia
23
depression
22
pneumonia
22
latent infection
22
mole
22
Mycoplasma
22
mitochondrial disease
22
endometrial cancer
21
Burkitt's lymphoma
21
herpes zoster
21
avian sarcoma
21
fits
21
glioma
21
abortion
20
GSH
20
XPV
20
gastric cancer
19
premature aging
19
diabetes
19
ACV
19
prostate cancer
19
Hodgkin's disease
19
thalassemia
18
abdominal aortic aneurysm
18
AAA
18
avian leukosis
18
systemic lupus erythematosus
17
chronic liver disease
17
hepatitis A
16
peripheral neuropathy
16
renal disease
16
reticuloendotheliosis
16
CMV retinitis
16
dengue
16
APC
16
epilepsy
16
neurological disease
15
lung carcinoma
15
West
15
EBV infection
15
Fanconi
15
Gilbert
15
viral hepatitis
14
chronic persistent hepatitis
14
acute promyelocytic leukemia
14
acute leukemia
14
DDP
14
suicide
14
ischemia
14
Haemophilus
14
B virus infection
14
Marek's disease
14
genital herpes
13
lipodystrophy
13
thrombocytopenia
13
Parkinson's disease
13
Brown
13
Huntington's disease
13
mimicry
13
Cockayne syndrome
13
metastases
13
PML
12
cystic fibrosis
12
chronic lymphocytic leukemia
12
respiratory disease
12
Chronic hepatitis B
12
cervical cancer
12
non-small cell lung cancer
12
PHA
12
leishmaniasis
12
stroke
12
XPG
12
stomatitis
11
meningitis
11
retinitis
11
rash
11
Human immunodeficiency virus type
11
adenoma
11
mitochondrial myopathy
11
erythroleukemia
11
solid tumor
11
more...
Symptom
starvation
42
ophthalmoplegia
41
ataxia
40
collapse
25
diarrhea
25
fatigue
13
weakness
11
seizures
10
anorexia
10
nausea
10
dysarthria
9
vomiting
8
pain
7
headache
7
exhaustion
5
chills
5
cough
4
nasal discharge
4
lethargy
4
abdominal pain
4
agitation
3
penile lesion
3
Ill
3
Halo
3
hepatomegaly
3
hypothermia
3
neuralgia
3
respiratory distress
3
tremor
3
Ataxic
3
dyspnea
2
apathy
2
myalgia
2
hypotonia
2
nausea and vomiting
2
HSA
2
angina
2
night sweats
2
pallor
2
cerebellar ataxia
2
splenomegaly
2
Fluctuation
2
blepharospasm
2
tachypnea
1
skin irritation
1
neurological disability
1
emaciation
1
Spots
1
wheezing
1
neck pain
1
dark urine
1
abiotrophy
1
rhinorrhea
1
insomnia
1
spasticity
1
abdominal discomfort
1
hepatosplenomegaly
1
twitching
1
CSR
1
thinning
1
adenitis
1
spasm
1
chorea
1
eds
1
photophobia
1
No toxic effect
1
erythema
1
sore throat
1
hyperoxia
1
leg pain
1
autodigestion
1
incoordination
1
DNA marker
1
Sensory ataxia
1
hemoptysis
1
acidity
1
livedo
1
Drug
DNase I
95
lysine
92
-deoxyadenosine
59
Gel
58
Acyclovir
50
PFA
47
AZT
41
AZT
41
Dermatol
37
caffeine
34
Asn
33
Mutagen
31
HPMPC
29
Ganciclovir
26
PMEA
26
Cidofovir
25
Fragment
16
MRC
16
NH3
16
ascorbate
15
ampicillin
15
IL-2
14
Adriamycin
13
lactose
12
AC2
11
Alanine
11
Ara-A
11
CDP
10
BLM
10
Glycerol
10
MAP
9
ddI
9
Nephron
9
ROS
9
IFN-gamma
8
MgSO4
8
Entecavir
8
Entecavir
8
THF
8
ABC
8
Clofarabine
7
IFN-beta
7
PMPA
7
Leaf
7
NADH
6
TTC
6
Fraction
6
CTX
6
CSF
6
Zovirax
5
TAT
5
Biopolymers
5
AGG
5
pyridoxal phosphate
4
Deoxyadenosine
4
nitroglycerin
4
CaCl2
4
CaCl2
4
Cardiovasc
4
G418
4
CTT
4
Diamminedichloroplatinum
4
CaCl2
4
Neocarzinostatin
4
RFP
4
VCR
4
TAC
4
Pronase
4
ACT
3
EE2
3
ROX
3
ADR
3
Triclosan
3
FCV
3
Adefovir dipivoxil
3
2'-Deoxyadenosine
3
PCP
3
Meth
3
G-CSF
3
Alliance
3
VCR
3
ADM
3
Sulpiride
3
Telbivudine
3
Secretin
3
Itraconazole
2
vitamin E
2
FeCl3
2
Fludarabine
2
Bayer
2
Mycophenolic acid
2
AraC
2
Fluorescein
2
Histidinol
2
Aztec
2
Nephron
2
CoCl2
2
CoCl2
2
Kenyan
2
Mizoribine
2
Tenofovir
2
Arsenic trioxide
2
EFV
2
ZnO
2
KCL
2
Growth hormone
2
Oxaliplatin
2
Indomethacin
2
Prednisolone
2
p75
2
Myricetin
2
Monit
2
FAD
2
Growth hormone
2
PTC
2
Hepatitis B immune globulin
2
Gastro
2
FLP
2
Valganciclovir
2
Lobucavir
1
HCH
1
CTX
1
Bestatin
1
CTC
1
Reverset
1
Idarubicin
1
TFT
1
NVP
1
TiO2
1
PE2
1
BH4
1
TAK
1
Dihydro
1
CCL
1
Gold sodium thiomalate
1
Activin
1
Bifidobacterium
1
Ranitidine
1
Sorafenib
1
Irofulven
1
CTA
1
Solon
1
Vitamin K2
1
Desferal
1
Tacrolimus
1
Anthramycin
1
balanced salt solution
1
Sodium valproate
1
Foscavir
1
Artesunate
1
DMAP
1
Alovudine
1
Glycyrrhiza
1
Botox
1
MTC
1
Peridex
1
Adozelesin
1
ETS
1
CMX
1
Metrizamide
1
more...
Enzyme
DNA polymerase
17007
reverse transcriptase
1094
endonuclease
589
RNA polymerase
557
DNA ligase
418
DNA ligase
418
RNase H
345
thymidine kinase
344
DNase
239
topoisomerase
199
ATPase
198
topoisomerase
174
phosphodiesterase
159
RNase
153
ribonucleotide reductase
150
protein kinase
141
RNase
140
ribonucleotide reductase
135
thymidylate synthase
87
3'-exonuclease
84
transcriptase
78
S1 nuclease
72
dihydrofolate reductase
71
PARP
69
alkaline phosphatase
68
deoxyribonuclease
65
polynucleotide kinase
65
cdc2
55
alanine aminotransferase
53
deoxyribonuclease
51
ACS
50
luciferase
49
beta-galactosidase
45
glutathione S-transferase
44
TdT
42
trypsin
41
ribonuclease
40
ribonuclease
39
thymidylate kinase
38
micrococcal nuclease
36
peroxidase
32
catalase
30
chloramphenicol acetyltransferase
29
deoxycytidine kinase
29
AP lyase
27
proteasome
27
IMP dehydrogenase
26
superoxide dismutase
26
protein kinase C
26
mitogen-activated protein kinase
25
Escherichia coli exonuclease III
25
ERK
24
lambda exonuclease
24
exonuclease I
23
ornithine decarboxylase
21
lysozyme
21
caspase-3
21
proteinase K
21
endodeoxyribonuclease
20
dUTPase
20
venom phosphodiesterase
20
APC
19
DNA methyltransferase
18
deaminase
17
poly(A) polymerase
16
dCMP deaminase
16
factor C
16
aspartate aminotransferase
15
beta-lactamase
15
thymidine phosphorylase
14
adenosine deaminase
14
adenosine deaminase
14
glyceraldehyde-3-phosphate dehydrogenase
14
lactate dehydrogenase
14
STR
14
LexA repressor
14
hypoxanthine-guanine phosphoribosyltransferase
13
calcineurin
13
exonuclease V
13
3'-phosphatase
13
subtilisin
12
focal adhesion kinase
12
glyceraldehyde-3-phosphate dehydrogenase
12
glyceraldehyde-3-phosphate dehydrogenase
11
glyceraldehyde-3-phosphate dehydrogenase
11
exodeoxyribonuclease
11
glyceraldehyde-3-phosphate dehydrogenase
11
cytochrome oxidase
11
thioredoxin reductase
10
endonuclease V
10
triphosphatase
10
Fpg protein
10
glutathione peroxidase
10
PRE
10
acid phosphatase
10
complex I
9
exonuclease VII
9
PDE
9
pyruvate kinase
9
phospholipase C
9
guanylate kinase
8
P-glycoprotein
8
aspartate transcarbamylase
8
neuraminidase
8
exoribonuclease
8
demethylase
8
RNase D
8
RNase T1
8
tyrosinase
8
pyruvate dehydrogenase
7
TGT
7
glucose-6-phosphate dehydrogenase
7
adenylate kinase
7
deoxycytidine deaminase
7
dCMP hydroxymethylase
7
nucleoside diphosphokinase
7
phosphoglycerate kinase
7
DNase V
6
endonuclease VII
6
gamma-glutamyl transpeptidase
6
cytidine deaminase
6
lipase
6
purine nucleoside phosphorylase
6
firefly luciferase
6
succinate dehydrogenase
6
AMPK
6
chaperonin
6
HIV-1 protease
6
pyruvate dehydrogenase
6
pyruvate dehydrogenase
6
deoxyguanosine kinase
6
AGT
5
alpha-amylase
5
CPT
5
CPT
5
UmuD protein
5
CGT
5
thrombin
5
MEK
5
adenylate cyclase
5
dTTPase
5
lysin
5
CPS
5
AST
5
RNA ligase
5
ATP sulfurylase
5
creatine kinase
5
CPT
5
uridine kinase
5
5'-nucleotidase
5
ATP synthase
5
DNA 3'-phosphatase
5
TAT
5
hexokinase
5
polynucleotide phosphorylase
5
tissue plasminogen activator
4
DNase II
4
orotidine-5'-phosphate decarboxylase
4
RNase III
4
RNase P
4
more...
Compound
DNA
12811
Dec
1209
ATP
607
TTP
546
phosphate
468
dATP
455
dCTP
429
dGTP
386
pyrimidine
351
pyrimidine
351
hydrogen
321
Mg2+
282
salt
271
manganese
238
oxygen
232
Clin
228
sodium
214
DAMP
203
alanine
191
sulfate
189
water
181
TMP
179
DEAE
172
dUTP
164
dCMP
164
glycerol
156
lysine
156
PPA
148
tyrosine
141
arginine
137
phosphonoacetic acid
131
methyl methanesulfonate
119
dGMP
112
Guo
111
bromide
111
Asp
108
His
108
SDS
107
ADP
103
Aphidicolin
102
Aphidicolin
102
pyrene
101
zinc
98
ADP
97
ADP
97
Phe
94
leucine
92
methionine
90
ammonium
90
CTP
88
GTP
84
serine
82
acetate
73
MgCl2
72
cysteine
71
urea
67
NH2
67
calcium
65
Adenine
65
AMP
65
threonine
59
uridine
59
Gly
57
potassium
55
nitrogen
54
ethanol
53
AZT
52
3TC
50
ACS
50
ACS
50
Acyclovir
48
ADP-ribose
48
copper
46
Ile
46
tryptophan
46
PPi
44
UTP
44
iron
42
PEG
41
NAD
40
EDTA
39
EDTA
39
dUMP
38
Ara-C
38
Tris
37
acrylamide
37
THF
37
Triton X-100
35
Optimal
35
tryptophan
34
caffeine
34
aldehyde
34
Tris
33
HCl
33
tryptophan
33
tryptophan
33
aldehyde
32
glucose
32
aspartic acid
29
silver
29
AAF
29
toluene
29
Foscarnet
29
aspartic acid
28
aspartic acid
28
aspartic acid
28
NAD
28
glutamate
27
DDP
26
galactose
26
pyridine
25
acridine
25
vinyl
25
H2O2
25
PMEA
25
TOF
24
BLM
24
methanol
24
adenylate
24
proline
24
valine
24
phosphorus
24
Cidofovir
24
glutamine
23
PEG
23
ammonia
23
TMP
22
PMA
22
Ara-C
22
A 3
21
methane
21
glutamic acid
21
3-aminobenzamide
21
TMP
21
phenol
21
nickel
21
TMP
21
Pac
21
chromium
20
Lac
20
fluorine
20
GSH
20
GSH
20
DMSO
20
PRPP
19
deoxyribose-5-phosphate
19
hydroxylamine
19
Thymidine
19
AAA
18
asparagine
18
Uracil
18
EMS
18
cAMP
18
8-OHdG
18
piperidine
17
Adriamycin
17
hydroxide
17
isoleucine
17
Ara-A
17
guanidine
17
more...