Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.7.7 (
DNA polymerase
)
17,007
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Nucleoside diphosphokinase
activity is present in highly purified preparations of
DNA polymerase
from Micrococcus luteus and Escherichia coli, and in a partially purified
DNA polymerase
from avian myeloblastosis virus. The activity is also observed in the protein fragment of molecular weight 76,000 that is produced by subtilisin cleavage of
DNA polymerase I
from E. coli. The NDP kinase activity in
DNA polymerase
preparations from M. luteus uses various ribo- and deoxyribonucleoside di- and triphosphates as substrates. The presence of this activity in preparations of
DNA polymerase
results in the apparent use of deoxyribonucleoside diphosphates as substrates for DNA synthesis, provided that some triphosphate is present to serve as a phosphate donor.
...
PMID:Nucleoside diphosphokinase activity associated with DNA polymerases. 433 52
