Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.7.6 (RNA polymerase)
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Human Gene/Protein
hTRFP 9.8
Elongin A-binding protein 1 9.8
small CTD phosphatase 1 9.8
RPLP0 protein 9.8
BRFU 9.8
GPN2 9.8
RPB11a 9.8
POLR1E 9.8
TAFI110 9.8
RNA polymerase I 9.8
General transcription factor IIB 9.8
TFIIIC63 9.8
EIF3S6IP 9.8
CYCT1b 9.8
mediator complex subunit 13-like 9.8
ZNF297B 9.8
ELOF1 9.8
RPC62 9.8
FAM27C 9.8
FAM103A1 9.8
transcription termination-antitermination factor 9.8
TAC12 9.8
NOPAR 9.8
TRAP80 9.8
elongation factor RNA polymerase II 9.8
TAF5 protein 9.8
TFIIIC35 9.8
RNA polymerase II 9.8
Mucin-like protocadherin 9.8
Rsc6p 9.8
PDZ domain containing 7 9.8
RNA nucleotidyltransferase (DNA-directed) 9.8
NFI-X3 9.8
POLR2J1 9.8
LALP70 9.8
Transcription factor II H 9.8
TAFI48 9.8
taf4b 9.8
Mitochondrial ribosomal protein L7/L12 9.8
C16orf33 9.8
RNA polymerase II associated protein 1 9.8
POLR3GL 9.8
POLR3C 9.8
TAFI63 9.8
TFIIF-alpha 9.8
BTF3 homologue 9.8
FAM57A 9.8
KIAA1257 9.8
NGDN 9.8
DNA-directed RNA polymerase 9.8
trithorax homolog, Drosophila 9.8
TAF(I)63 9.8
hepatoma-derived growth factor 2 9.8
transcription factor B2, mitochondrial 9.8
POLR2J2 9.8
interacts with Spt6 9.8
Mediator complex subunit 29 9.8
SRG5 9.8
cyclin T1b 9.8
RBP95 9.8
POLR2J3 9.8
RPA194 9.7
RPB11 9.7
MED6 9.7
Selectivity Factor 1 9.7
RPB3 9.7
CTD kinase 9.6
TAF(I)48 9.6
SNAP43 9.6
RPAP2 9.6
Cyclin T2 9.6
RPA135 9.6
RPB10 9.6
hSPT5 9.6
TFIIIB 9.5
RPB9 9.5
TAF1C 9.5
TFIIF 9.5
SNAP50 9.5
RPC6 9.5
more...
Disease
DDRD 9.8
Non-ischemic dilated cardiomyopathy 8.8
Benign mesenchymal neoplasms 8.8
PPR2 8.5
RP27 8.2
Swine Disease 8.2
HAE III 7.8
SXI2 7.8
XPB 7.5
SXI1 7.5
Occult carcinoma 7.2
Systemic sclerosis sine scleroderma 7.0
DGS2 6.8
CSB 6.8
Scleroderma renal crisis 6.8
CSB 6.8
Cockayne syndrome 6.8
BMH 6.7
MDC1D 6.7
IMD1 6.7
Tumor embolus 6.7
GDD 6.6
DECD 6.5
oculocerebrofacial syndrome 6.4
Paraneoplastic encephalomyelitis 6.4
Flavivirus infection 6.3
Keratolytic winter erythema 6.2
CHED 6.2
DFNB18 6.2
Xeroderma pigmentosum group C 6.2
Gopalan 6.1
Pleomorphic rhabdomyosarcoma 6.1
DFNB49 6.1
trichothiodystrophy 6.1
AOA2 5.9
HPC4 5.9
XPE 5.9
XPD 5.8
Sluder 5.8
HRPT2 5.8
renal scleroderma 5.7
Vaccinia virus infection 5.7
Essential mixed cryoglobulinemia 5.7
Rinderpest 5.7
Jembrana disease 5.7
ALS4 5.6
Disseminated cancer 5.6
Perlman syndrome 5.5
WSN 5.5
WSN 5.4
Avian encephalomyelitis 5.4
myeloblastosis 5.4
Rotavirus gastroenteritis 5.4
Congo hemorrhagic fever 5.4
vaccinia 5.3
Xeroderma 5.3
GALK 5.3
Wiedemann-Rautenstrauch syndrome 5.3
relapsed childhood ALL 5.3
XPG 5.3
Adynamic bone disease 5.2
viral leukemogenesis 5.2
DFNB31 5.1
FRDA 5.1
SPG2 5.0
XP-A 5.0
Border Disease 5.0
Lymphocystis disease 5.0
CMCT 4.9
Ehlers-Danlos syndrome type VII 4.9
viral cardiomyopathy 4.9
CRST syndrome 4.9
DFNA5 4.9
NS2 4.9
CACA 4.9
Spindle epithelial tumor with thymus-like differentiation 4.8
PIE 4.7
La Crosse encephalitis 4.7
Spondyloepiphyseal dysplasia tarda 4.6
AD5 4.6
more...
Symptom
Opiate withdrawal symptoms 8.2
RNA marker 5.2
PUO 5.1
astasia 3.9
Ear swelling 3.9
Skin symptoms 3.7
No toxic effect 3.5
starvation 3.4
blemishes 3.2
Spots 2.6
eds 2.6
autodigestion 2.5
scaly skin 2.4
skin irritant 2.3
CSR 1.4
loss of taste 1.3
general problem 1.1
muscle cramps 1.0
tenesmus 0.9
rundown 0.9
microbial colonization 0.8
sore throat 0.7
retching 0.7
adenitis 0.7
decreased appetite 0.6
ataxia 0.6
diarrhea 0.5
twitching 0.4
cachexia 0.4
lethargy 0.4
skin irritation 0.3
chest tightness 0.3
acute stress 0.2
renal colic 0.2
hepatosplenomegaly 0.0
incoordination 0.0
cerebellar ataxia 0.0
collapse -0.0
neurological disability -0.0
hypotonia -0.1
arthralgia -0.2
joint stiffness -0.2
chills -0.2
cough -0.2
myalgia -0.3
abnormal gait -0.3
hypoproteinemia -0.3
nasal congestion -0.3
night sweats -0.4
wheezing -0.4
tachypnea -0.5
Mills -0.5
fasciculation -0.5
spasticity -0.5
shortness of breath -0.5
asthenia -0.5
nasal discharge -0.6
splenomegaly -0.6
Neuropathic pain -0.6
exhaustion -0.7
physical appearance -0.7
tremor -0.8
bloating -0.9
dystonia -0.9
epigastric pain -0.9
anorexia -0.9
hyperoxia -0.9
vomiting -1.0
nausea -1.0
oliguria -1.0
dysarthria -1.0
acidity -1.1
sneezing -1.1
respiratory distress -1.1
acute pain -1.1
dyspnea -1.1
Ill -1.3
rhinorrhea -1.3
paresthesia -1.4
pallor -1.5
more...
Drug
Rifalazil 7.2
Tribenoside 7.0
Lazabemide 6.8
Balhimycin 6.7
Flavopiridol 6.3
Capravirine 6.2
7-Methylguanosine 6.2
AraC 5.7
DNase I 5.6
DPE 5.5
CFPM 5.4
Pentaerythritol tetranitrate 5.3
Urso 5.2
8-Azaguanine 5.1
Tora 5.1
Tenofovir disoproxil fumarate 5.0
Gentian 4.8
ProstaScint 4.8
K201 4.8
Interferon beta-1a 4.8
Avilamycin 4.5
Peramivir 4.5
Rifaximin 4.5
Olomoucine 4.4
Raltegravir 4.3
Mycophenolic acid 4.2
Tenofovir 4.2
Epidoxorubicin 4.1
Sinefungin 4.1
Frovatriptan 4.1
RFP 4.0
PMPA 4.0
Truvada 3.9
beta-Galactosidase 3.9
Tween 40 3.8
RBT 3.7
AGG 3.7
Trabectedin 3.7
TAK 3.6
Trifluoroethanol 3.6
FCV 3.6
Gallium nitrate 3.5
Telbivudine 3.5
Truvada 3.4
Etravirine 3.4
Domin 3.4
Alanine 3.4
1,8-Cineole 3.4
Epivir 3.3
ETS 3.3
URF 3.3
Azacytidine 3.3
-deoxyadenosine 3.3
Maraviroc 3.3
ID2 3.3
Mizoribine 3.2
Gel 3.2
Ddc 3.2
EFV 3.2
Crixivan 3.1
Crixivan 3.1
lysine 3.1
ddI 3.0
Intron A 3.0
L-Ser 3.0
Ara-A 3.0
Crixivan 3.0
anti-RSV 3.0
Cytidine 3.0
TPV 3.0
Poudre 2.9
Indinavir 2.9
Adefovir dipivoxil 2.9
Ranitidine 2.9
CDX 2.8
Fraction 2.8
TEL 2.8
Intron A 2.8
AZT 2.8
Intron A 2.8
more...
Enzyme
RNA polymerase 9.8
CTD kinase 9.5
transcriptase 9.1
kallikrein 12 8.2
calpain 5 8.2
cytochrome c methyltransferase 8.2
endoribonuclease V 7.8
lysine N6-hydroxylase 7.8
ATP(CTP):tRNA nucleotidyltransferase 7.6
nucleoside triphosphate phosphohydrolase 7.5
salutaridinol 7-O-acetyltransferase 7.5
phosphoglucokinase 7.5
pseudouridylate synthase 7.4
glucosylglycerol-phosphate synthase 7.2
vanillate demethylase 7.2
ecdysone oxidase 6.6
EC 1.1.1.101 6.5
UDP-N-acetylenolpyruvoylglucosamine reductase 6.5
salutaridine reductase 6.5
cephalosporin C deacetylase 6.5
poly(A) polymerase 6.3
Protein 2 6.3
glutaconate CoA-transferase 6.2
naphthoate synthase 6.2
mycocerosic acid synthase 6.0
EC 2.7.7.25 6.0
elongation factor (EF) 6.0
YdiB 5.8
RNase III 5.7
stringent factor 5.7
S1 nuclease 5.7
histone acetyltransferase 5.7
allophanate hydrolase 5.7
Cypridina luciferase 5.7
phenylacetaldehyde dehydrogenase 5.6
FtsH protease 5.6
dCMP hydroxymethylase 5.5
acetylornithinase 5.5
acetylornithine aminotransferase 5.5
YgjG 5.5
L-ribulose-5-phosphate 4-epimerase 5.5
Lys4 5.5
GDP-mannose dehydrogenase 5.5
lambda exonuclease 5.5
RNase H 5.4
levanase 5.4
CMP-KDO synthetase 5.4
N-acetylglucosamine-6-phosphate deacetylase 5.4
RNase P 5.3
endodeoxyribonuclease 5.3
phosphoenolpyruvate mutase 5.3
BCKDH 5.3
dihydrodipicolinate reductase 5.2
exonuclease VII 5.2
levanase 5.2
RNA ligase 5.2
RNase PH 5.2
threonine synthase 5.2
3C protease 5.1
fructose-2,6-bisphosphatase 5.1
RNase T1 5.1
tRNase Z 5.1
exodeoxyribonuclease 5.1
GTP cyclohydrolase II 5.1
DNA 3'-phosphatase 5.0
site-1 protease 5.0
IMP dehydrogenase 5.0
deoxycytidine deaminase 5.0
CFA synthase 5.0
granzyme M 5.0
muconolactone isomerase 5.0
enzyme X 5.0
polynucleotide kinase 5.0
exoribonuclease 5.0
micrococcal nuclease 4.9
1,3-propanediol dehydrogenase 4.9
AMP nucleosidase 4.9
DNA polymerase 4.9
dCTPase 4.9
PepX 4.9
more...
Compound
C6H12OS2 9.8
Rifamycin O 9.8
Aclacinomycin B 9.8
C6H12OS2 9.8
Rifamycin AF 013 9.8
C6H12OS2 9.8
C6H12OS2 9.8
Rifamycin AF 013 9.8
3-chloro-2-methylbenzoic acid 9.8
Rifamycin AF 013 9.8
C6H12OS2 9.8
Rifamycin AF 013 9.8
C6H12OS2 9.8
C6H12OS2 9.8
C6H12OS2 9.8
Rifamycin AF 013 9.8
C6H12OS2 9.8
Rifamycin O 9.8
Rifamycin AF 013 9.8
C6H12OS2 9.8
5-Iodouridine 9.8
Macbecin I 8.8
Marasmic acid 8.8
U-20,661 8.8
4-phenyl-1,2,4-triazolidine-3,5-dione 8.8
Tirandamycin 8.8
alpha-Amanitin 8.6
Streptolydigin 8.5
9-beta-D-arabinofuranosyl-9H-purine-6-thiol, 8.2
Thiolutin 7.8
4'-Epiadriamycin 7.8
Salutaridine 7.8
N-Trifluoroacetyladriamycin 7.8
Rifamycin S 7.8
AF/ABDP 7.8
arsonoacetic acid 7.8
DADI 7.8
Rifamycin 7.7
Robinin 7.5
AF/ABDP 7.5
3-hydroxy-2-pyrazinecarboxamide 7.5
Robinin 7.5
Rifamycin 7.5
Rifamycin 7.4
TBP 7.4
Dihydrouracil 7.4
TIF 7.2
A 143 7.2
Streptovitacin A 7.2
Allocryptopine 7.2
Trachelogenin 7.2
Allocryptopine 7.2
TBP 7.2
Granaticin 7.0
GppppG 7.0
ergosta-7,22-dien-3-one 6.8
1-Methyladenosine 6.8
Resistomycin 6.8
Anticapsin 6.8
Rifamycin 6.8
Illudin S 6.7
Potassium permanganate 6.7
Zwittermicin A 6.7
Deoxyribonolactone 6.7
Balhimycin 6.7
Lomofungin 6.5
Myrtenal 6.5
AZU 6.5
Myrtenal 6.5
benzyl propionate 6.5
Fagaronine 6.5
Triostin A 6.4
UMP 6.3
MnO4 6.3
Hedamycin 6.2
DNAP 6.2
7-Methylguanosine 6.2
DuP 697 6.2
2,3,4,9-tetrahydro-1H-carbazole 6.2
Bicyclomycin 6.2
more...