Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.7.6 (
RNA polymerase
)
34,946
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
RNA polymerase II
10339
Mol
5325
RNA polymerase I
4133
Sep
2396
Pol
1883
histone
1451
tRNA
1033
ATP
945
polypeptide
851
pol
804
Gen
638
histone H3
492
TATA-binding protein
450
DNase I
438
TFIID
415
TFIIB
397
transcription elongation factor
391
GTP
377
cytokine
373
p53
370
fused
363
ATPase
355
DNA polymerase
353
Pseudomonas
349
TFIIH
348
transcriptional activator
326
thymus
322
ribonucleoprotein
312
endonuclease
294
phosphatase
289
AMP
276
helicase
266
general transcription factor
260
interferon
260
TBP
248
TFIIIB
247
cyclin
245
RNase
245
SP6
233
TFIIF
227
housekeeping
227
NMR
221
RPB2
211
methyltransferase
209
CDK9
200
SDS
199
glycoprotein
194
transcriptional regulator
189
ribosomal protein
183
SWI
181
p300
181
TFIIIC
173
ubiquitin
171
cryptic
171
TFIIS
168
NTP
168
threonine
166
insulin
163
Polymerase
163
proteasome
162
histone deacetylase
161
DNA-binding domain
161
CTP
156
tumor necrosis factor
154
CD4
150
cyclin-dependent kinase
149
Rho
148
phosphoprotein
147
topoisomerase I
147
Sp1
147
RPB1
146
DNA-binding protein
145
nuclear protein
143
histone acetyltransferase
142
UBF
141
telomeric
140
lipopolysaccharide
137
unknown function
135
TFIIA
134
PB1
132
more...
Disease
cancer
1462
tumor
947
HIV
772
influenza
566
immunodeficiency
504
vaccinia
462
leukemia
347
Mycobacterium
315
tuberculosis
281
virus infection
278
breast cancer
259
hepatitis C
251
cold
213
hepatocellular carcinoma
210
SDS
199
tumorigenesis
192
AIDS
191
stomatitis
188
carcinoma
186
herpes simplex
161
hepatitis
157
infectious diseases
144
Cockayne syndrome
139
carcinogenesis
132
SARS
121
acute myeloid leukemia
120
plaque
114
hepatitis B
114
Epstein
106
lymphoma
105
gastroenteritis
105
MCF
95
Infection
94
adenocarcinoma
94
prostate cancer
93
melanoma
92
Klebsiella
91
cytomegalovirus
91
PSS
80
systemic lupus erythematosus
79
diabetes
71
tumor growth
71
lung cancer
70
XPB
68
ATM
68
chronic hepatitis
67
multiple myeloma
67
chronic myeloid leukemia
67
tumor progression
67
metastases
66
xeroderma pigmentosum
65
CSB
65
CSB
65
neuroblastoma
64
avian influenza
64
sarcoma
63
uterus
62
pheochromocytoma
61
Chlamydia
59
dengue
59
gastric cancer
57
West
57
PCC
57
cholera
57
pneumonia
57
colorectal cancer
57
measles
56
viremia
55
XPD
54
retinoblastoma
54
encephalitis
52
acute lymphoblastic leukemia
52
abdominal aortic aneurysm
51
glioma
51
rabies
51
pertussis
51
Alzheimer's disease
50
mouth disease
50
Recruitment
49
cirrhosis
47
more...
Symptom
starvation
290
diarrhea
88
collapse
31
pain
28
ataxia
27
cough
22
seizures
22
vomiting
18
fatigue
17
headache
15
dyspnea
14
nausea
13
tremor
12
weakness
11
respiratory distress
10
exhaustion
9
cachexia
8
lethargy
8
acidity
8
anorexia
8
splenomegaly
7
arthralgia
7
eds
7
myalgia
6
acute stress
6
anesthesia
6
hypotonia
6
abdominal pain
5
spasticity
5
hepatosplenomegaly
5
sore throat
5
dystonia
5
Ill
5
shortness of breath
4
functional recovery
4
chills
4
cerebellar ataxia
4
wheezing
4
thinning
3
agitation
3
overweight
3
skin irritation
3
twitching
3
Spots
3
hyperoxia
3
CSR
2
muscle cramps
2
incoordination
2
epigastric pain
2
spasm
2
general problem
2
dizziness
2
microbial colonization
2
hunger
2
angina
2
decreased appetite
2
tachypnea
2
analgesia
2
asthenia
2
flushing
2
paresthesia
2
nausea and vomiting
2
astasia
2
back pain
2
hepatomegaly
2
acute pain
2
dysarthria
2
autodigestion
2
paraparesis
1
chest pain
1
apathy
1
Opiate withdrawal symptoms
1
Neuropathic pain
1
sneezing
1
Welt
1
adenitis
1
physical appearance
1
nasal discharge
1
nasal congestion
1
night sweats
1
more...
Drug
lysine
543
DNase I
439
Gel
152
lactose
74
IFN-gamma
74
IL-2
65
Dermatol
65
AraC
59
Asn
44
CSF
32
Alanine
32
ETS
29
NADH
29
MAP
24
Leaf
23
Cardiovasc
22
RFP
22
-deoxyadenosine
22
caffeine
21
Fraction
20
ABC
20
AZT
20
AZT
20
Flavopiridol
18
TAT
17
ampicillin
15
Glycerol
15
PMPA
14
Adriamycin
13
Ranitidine
13
p75
13
IFN-beta
13
TAK
13
Nephron
13
MRC
12
nitroglycerin
12
AGG
11
Retinoic acid
10
EE2
9
MOF
9
G418
9
Ethanol
9
ETA
9
ENT
9
Monit
9
FAD
9
ROS
9
TTC
9
NH3
8
ascorbate
8
Tenofovir
8
ROC
8
Angiotensin II
8
Fragment
8
Biopolymers
8
ICI
8
Capsicum
7
Alliance
7
CAM
7
Mycophenolic acid
7
Mutagen
7
TAC
7
Bifidobacterium
7
DPE
7
Heme
7
Dial
7
beta-Galactosidase
7
GEO
7
Forskolin
7
L-tyrosine
6
Tenofovir disoproxil fumarate
6
Imatinib
6
CTC
6
TEL
6
Adenosine triphosphate
6
VCR
6
CaCl2
6
Gelatin
6
ACT
6
ALA
5
more...
Enzyme
RNA polymerase
34946
transcriptase
5737
protein kinase
570
DNA polymerase
557
reverse transcriptase
516
RNase
417
ATPase
407
RNase
393
endonuclease
294
ERK
277
luciferase
252
DNase
211
S1 nuclease
208
beta-galactosidase
198
mitogen-activated protein kinase
191
cdc2
172
proteasome
168
topoisomerase
156
histone acetyltransferase
154
ribonuclease
142
ribonuclease
142
topoisomerase
138
chloramphenicol acetyltransferase
136
RNase H
130
catalase
117
glutathione S-transferase
114
CTD kinase
109
focal adhesion kinase
98
micrococcal nuclease
95
trypsin
93
ACS
91
alkaline phosphatase
91
protein kinase C
86
lysozyme
78
glyceraldehyde-3-phosphate dehydrogenase
73
glyceraldehyde-3-phosphate dehydrogenase
71
dihydrofolate reductase
67
thymidine kinase
66
calcineurin
65
neuraminidase
63
RNase P
60
RNase III
59
glyceraldehyde-3-phosphate dehydrogenase
58
poly(A) polymerase
56
superoxide dismutase
55
DNA ligase
53
DNA ligase
53
DNA methyltransferase
53
glyceraldehyde-3-phosphate dehydrogenase
52
ATP synthase
52
glyceraldehyde-3-phosphate dehydrogenase
52
RNase T1
47
triphosphatase
45
APC
45
firefly luciferase
43
MEK
43
adenylate cyclase
43
PARP
42
P-glycoprotein
42
peroxidase
41
ornithine decarboxylase
39
caspase-3
38
demethylase
37
Protein 2
36
CD10
34
NO synthase
34
beta-lactamase
33
ribonucleotide reductase
33
alanine aminotransferase
32
IMP dehydrogenase
32
collagenase
32
thrombin
31
histidine kinase
30
complex I
28
ribonucleotide reductase
28
phosphodiesterase
28
chymotrypsin
27
phospholipase C
27
RNA ligase
27
phosphatidylinositol 3-kinase
26
more...
Compound
DNA
12173
Dec
2525
ATP
946
lysine
651
serine
568
salt
509
phosphate
468
arginine
412
GTP
399
Clin
395
sodium
385
alanine
357
UTP
354
His
330
glucose
321
tyrosine
314
sulfate
310
cAMP
306
threonine
294
zinc
287
AMP
274
oxygen
269
calcium
268
nitrogen
265
uridine
262
TBP
248
TBP
248
pyrimidine
245
pyrimidine
245
Mg2+
242
water
241
cysteine
241
methionine
240
leucine
231
Guo
223
SDS
221
DEAE
215
glycerol
212
hydrogen
210
tryptophan
199
ammonium
192
manganese
183
iron
181
acetate
176
Phe
167
galactose
159
CTP
157
Histone
132
proline
129
tryptophan
129
tryptophan
128
tryptophan
128
urea
127
Asp
126
Rifampicin
125
potassium
125
ADP
120
ADP
113
ADP
112
glutamate
109
NH2
108
nitric oxide
107
glutamine
105
Gly
105
bromide
104
ethanol
97
UMP
96
GMP
96
retinoic acid
90
ACS
88
ACS
88
TNF
87
Ile
82
copper
80
nitrate
73
EDTA
71
EDTA
70
tetraphosphate
69
acrylamide
68
CAM
67
more...