Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.7.6 (RNA polymerase)
 34,946 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
RNA polymerase II 10339
Mol 5325
RNA polymerase I 4133
Sep 2396
Pol 1883
histone 1451
tRNA 1033
ATP 945
polypeptide 851
pol 804
Gen 638
histone H3 492
TATA-binding protein 450
DNase I 438
TFIID 415
TFIIB 397
transcription elongation factor 391
GTP 377
cytokine 373
p53 370
fused 363
ATPase 355
DNA polymerase 353
Pseudomonas 349
TFIIH 348
transcriptional activator 326
thymus 322
ribonucleoprotein 312
endonuclease 294
phosphatase 289
AMP 276
helicase 266
general transcription factor 260
interferon 260
TBP 248
TFIIIB 247
cyclin 245
RNase 245
SP6 233
housekeeping 227
TFIIF 227
NMR 221
RPB2 211
methyltransferase 209
CDK9 200
SDS 199
glycoprotein 194
transcriptional regulator 189
ribosomal protein 183
p300 181
SWI 181
TFIIIC 173
ubiquitin 171
cryptic 171
TFIIS 168
NTP 168
threonine 166
Polymerase 163
insulin 163
proteasome 162
histone deacetylase 161
DNA-binding domain 161
CTP 156
tumor necrosis factor 154
CD4 150
cyclin-dependent kinase 149
Rho 148
topoisomerase I 147
phosphoprotein 147
Sp1 147
RPB1 146
DNA-binding protein 145
nuclear protein 143
histone acetyltransferase 142
UBF 141
telomeric 140
lipopolysaccharide 137
unknown function 135
TFIIA 134
PB1 132
collagen 127
estrogen receptor 125
H2A 120
CRP 120
phosphorylating 120
membrane protein 120
cyclin T1 119
DNA gyrase 119
CDK7 117
H2B 115
IL-6 115
nov 114
ADP 112
beta-globin 110
CTD kinase 109
RNase H 109
histone H4 108
RNA-binding protein 105
erythroid 104
IFN 103
UTR 102
c-myc 102
GAL4 101
lymphoid 99
DNase 99
A-T 99
zinc finger 99
transcriptional repressor 94
DNA-directed RNA polymerase 93
SARS 92
ORF 92
calmodulin 91
mer 91
alkaline phosphatase 90
endoplasmic reticulum 89
RNP 89
CBP 89
FIB 89
ACS 88
RNase III 87
TNF 87
dimeric 86
IL-4 85
FACT 85
p21 85
transactivator 84
IFN-gamma 84
Transcription factor 84
c-Myc 84
alternatively spliced 81
RNA polymerase subunit 81
TAF 81
interleukin-6 79
SL1 79
La protein 78
lysozyme 77
Dicer 77
P protein 77
snRNP 76
integrase 76
GMP 75
TAK 74
vascular endothelial growth factor 73
splicing factor 73
IL-8 73
hsp70 73
TNF-alpha 72
beta-actin 72
p65 72
protease inhibitor 72
cyclin T 72
IL-10 72
E.coli 71
gut 70
ras 70
membrane-bound 70
histone H1 69
chemokine 69
MYC 68
interferon-gamma 68
more...
Disease
cancer 1462
tumor 947
HIV 772
influenza 566
immunodeficiency 504
vaccinia 462
leukemia 347
Mycobacterium 315
tuberculosis 281
virus infection 278
breast cancer 259
hepatitis C 251
cold 213
hepatocellular carcinoma 210
SDS 199
tumorigenesis 192
AIDS 191
stomatitis 188
carcinoma 186
herpes simplex 161
hepatitis 157
infectious diseases 144
Cockayne syndrome 139
carcinogenesis 132
SARS 121
acute myeloid leukemia 120
hepatitis B 114
plaque 114
Epstein 106
gastroenteritis 105
lymphoma 105
MCF 95
Infection 94
adenocarcinoma 94
prostate cancer 93
melanoma 92
cytomegalovirus 91
Klebsiella 91
PSS 80
systemic lupus erythematosus 79
tumor growth 71
diabetes 71
lung cancer 70
ATM 68
XPB 68
multiple myeloma 67
tumor progression 67
chronic hepatitis 67
chronic myeloid leukemia 67
metastases 66
CSB 65
xeroderma pigmentosum 65
CSB 65
avian influenza 64
neuroblastoma 64
sarcoma 63
uterus 62
pheochromocytoma 61
Chlamydia 59
dengue 59
gastric cancer 57
pneumonia 57
West 57
PCC 57
colorectal cancer 57
cholera 57
measles 56
viremia 55
XPD 54
retinoblastoma 54
acute lymphoblastic leukemia 52
encephalitis 52
glioma 51
abdominal aortic aneurysm 51
rabies 51
pertussis 51
Alzheimer's disease 50
mouth disease 50
Recruitment 49
scleroderma 47
cirrhosis 47
malaria 46
squamous cell carcinoma 46
AAA 46
ischemia 46
myeloblastosis 46
NS3 45
CAP 43
Leukemia 41
Ewing's sarcoma 41
sepsis 41
hypertension 41
obesity 40
colon cancer 40
bends 40
Adenovirus 40
Newcastle disease 39
pancreatic cancer 39
mammary tumor 38
acute promyelocytic leukemia 38
anemia 38
osteosarcoma 37
Mycoplasma 37
CSA 37
Kaposi's sarcoma 36
atherosclerosis 36
Yersinia 36
renal cell carcinoma 35
ovarian cancer 35
Hippel 34
ABL 34
asthma 33
WSN 33
Blocking 33
hemorrhagic fever 33
WSN 33
respiratory disease 33
rheumatoid arthritis 32
chronic lymphocytic leukemia 32
Rous sarcoma 32
African swine fever 31
amyotrophic lateral sclerosis 31
PML 30
Bordetella 30
cystic fibrosis 30
leukemogenesis 29
erythroleukemia 29
acute leukemia 29
trichothiodystrophy 28
chronic lymphocytic leukemia 28
sepsis 28
NS2 28
mental retardation 27
Haemophilus 27
liver cancer 27
depression 27
mental retardation 27
B-cell lymphoma 27
liver disease 27
glioblastoma 27
Burkitt's lymphoma 27
toxic shock syndrome 26
hepatitis A 26
FUS 25
lupus 25
non-small cell lung cancer 25
hepatitis E 24
plague 24
Dissociation 24
herpes 24
lung carcinoma 24
coxsackievirus 24
autoimmune disease 24
WT1 23
minimal residual disease 23
renal disease 23
dehydration 23
stroke 23
viral diarrhea 22
bronchitis 22
more...
Symptom
starvation 290
diarrhea 88
collapse 31
pain 28
ataxia 27
seizures 22
cough 22
vomiting 18
fatigue 17
headache 15
dyspnea 14
nausea 13
tremor 12
weakness 11
respiratory distress 10
exhaustion 9
acidity 8
cachexia 8
anorexia 8
lethargy 8
splenomegaly 7
arthralgia 7
eds 7
acute stress 6
anesthesia 6
myalgia 6
hypotonia 6
abdominal pain 5
dystonia 5
Ill 5
spasticity 5
hepatosplenomegaly 5
sore throat 5
chills 4
cerebellar ataxia 4
shortness of breath 4
functional recovery 4
wheezing 4
thinning 3
agitation 3
Spots 3
overweight 3
twitching 3
hyperoxia 3
skin irritation 3
incoordination 2
CSR 2
spasm 2
general problem 2
dizziness 2
dysarthria 2
angina 2
tachypnea 2
flushing 2
analgesia 2
asthenia 2
hepatomegaly 2
paresthesia 2
hunger 2
nausea and vomiting 2
microbial colonization 2
astasia 2
decreased appetite 2
back pain 2
epigastric pain 2
acute pain 2
muscle cramps 2
autodigestion 2
paraparesis 1
chest pain 1
apathy 1
Opiate withdrawal symptoms 1
Neuropathic pain 1
sneezing 1
Welt 1
adenitis 1
physical appearance 1
nasal discharge 1
nasal congestion 1
night sweats 1
cyanosis 1
skin irritant 1
tenesmus 1
loss of taste 1
rhinorrhea 1
neurological disability 1
numbness 1
rundown 1
fasciculation 1
syncope 1
Skin symptoms 1
pallor 1
abnormal gait 1
Mills 1
Ear swelling 1
paresis 1
Wind 1
scaly skin 1
RNA marker 1
stigma 1
oliguria 1
insomnia 1
chest tightness 1
PUO 1
polyuria 1
joint stiffness 1
ophthalmoplegia 1
hypercapnia 1
erythema 1
hypoproteinemia 1
hypothermia 1
colic 1
low back pain 1
retching 1
shoulder pain 1
blemishes 1
bloating 1
myoclonus 1
distraction 1
renal colic 1
regurgitation 1
No toxic effect 1
Drug
lysine 543
DNase I 439
Gel 152
lactose 74
IFN-gamma 74
Dermatol 65
IL-2 65
AraC 59
Asn 44
Alanine 32
CSF 32
ETS 29
NADH 29
MAP 24
Leaf 23
Cardiovasc 22
-deoxyadenosine 22
RFP 22
caffeine 21
AZT 20
AZT 20
ABC 20
Fraction 20
Flavopiridol 18
TAT 17
ampicillin 15
Glycerol 15
PMPA 14
IFN-beta 13
Adriamycin 13
p75 13
Ranitidine 13
TAK 13
Nephron 13
nitroglycerin 12
MRC 12
AGG 11
Retinoic acid 10
Ethanol 9
FAD 9
ETA 9
TTC 9
ROS 9
MOF 9
Monit 9
G418 9
EE2 9
ENT 9
ICI 8
Fragment 8
NH3 8
Biopolymers 8
Angiotensin II 8
ascorbate 8
Tenofovir 8
ROC 8
Alliance 7
Heme 7
TAC 7
GEO 7
Forskolin 7
Mycophenolic acid 7
beta-Galactosidase 7
DPE 7
Bifidobacterium 7
Mutagen 7
CAM 7
Capsicum 7
Dial 7
Imatinib 6
CTC 6
Adenosine triphosphate 6
TEL 6
ACT 6
Tenofovir disoproxil fumarate 6
Gelatin 6
VCR 6
L-tyrosine 6
CaCl2 6
Growth hormone 5
Growth hormone 5
Raltegravir 5
MDS 5
PTC 5
Activin 5
IL-11 5
ALA 5
CaCl2 5
CaCl2 5
Itraconazole 5
BLM 5
CDP 5
Histamine 5
PFA 5
Rifaximin 5
Etoposide 4
Rifalazil 4
vitamin E 4
CTC 4
FLP 4
R1881 4
DHT 4
DHT 4
Nephron 4
pyridoxal phosphate 4
ddI 4
NVP 4
anti-RSV 4
Nitric Oxide 4
PCP 4
ID2 3
Indomethacin 3
PTH 3
ZnCl2 3
THF 3
citric acid 3
Pronase 3
Secretin 3
ZnCl2 3
Tween 40 3
Isoniazid 3
Phosphatidylserine 3
FeCl3 3
FCV 3
Estrogens 3
Adenosine deaminase 3
Truvada 3
Gleevec 3
CPR 3
Imiquimod 2
niacin 2
ADM 2
HCG 2
GRF 2
BoNT/A 2
IPM 2
Papain 2
L-Ser 2
Lovastatin 2
Ramipril 2
Maraviroc 2
CDX 2
EFV 2
KGF 2
PMEA 2
Asthma 2
Trabectedin 2
DM1 2
Infliximab 2
Gramicidin 2
Coral 2
Luteinizing 2
Fludarabine 2
ADR 2
Areca 2
Tacrolimus 2
CTA 2
Dihydro 2
Guanidine 2
CCL 2
more...
Enzyme
RNA polymerase 34946
transcriptase 5737
protein kinase 570
DNA polymerase 557
reverse transcriptase 516
RNase 417
ATPase 407
RNase 393
endonuclease 294
ERK 277
luciferase 252
DNase 211
S1 nuclease 208
beta-galactosidase 198
mitogen-activated protein kinase 191
cdc2 172
proteasome 168
topoisomerase 156
histone acetyltransferase 154
ribonuclease 142
ribonuclease 142
topoisomerase 138
chloramphenicol acetyltransferase 136
RNase H 130
catalase 117
glutathione S-transferase 114
CTD kinase 109
focal adhesion kinase 98
micrococcal nuclease 95
trypsin 93
ACS 91
alkaline phosphatase 91
protein kinase C 86
lysozyme 78
glyceraldehyde-3-phosphate dehydrogenase 73
glyceraldehyde-3-phosphate dehydrogenase 71
dihydrofolate reductase 67
thymidine kinase 66
calcineurin 65
neuraminidase 63
RNase P 60
RNase III 59
glyceraldehyde-3-phosphate dehydrogenase 58
poly(A) polymerase 56
superoxide dismutase 55
DNA methyltransferase 53
DNA ligase 53
DNA ligase 53
glyceraldehyde-3-phosphate dehydrogenase 52
glyceraldehyde-3-phosphate dehydrogenase 52
ATP synthase 52
RNase T1 47
triphosphatase 45
APC 45
adenylate cyclase 43
firefly luciferase 43
MEK 43
P-glycoprotein 42
PARP 42
peroxidase 41
ornithine decarboxylase 39
caspase-3 38
demethylase 37
Protein 2 36
CD10 34
NO synthase 34
ribonucleotide reductase 33
beta-lactamase 33
collagenase 32
alanine aminotransferase 32
IMP dehydrogenase 32
thrombin 31
histidine kinase 30
phosphodiesterase 28
complex I 28
ribonucleotide reductase 28
chymotrypsin 27
phospholipase C 27
RNA ligase 27
phosphatidylinositol 3-kinase 26
citrate synthase 25
renin 25
exoribonuclease 25
diaphorase 24
deoxyribonuclease 24
lactate dehydrogenase 24
nitrate reductase 23
nitrate reductase 23
polynucleotide phosphorylase 23
nitrate reductase 23
nitrate reductase 23
chaperonin 23
polynucleotide kinase 23
nitrate reductase 22
nitrate reductase 22
deaminase 22
beta-glucuronidase 22
deoxyribonuclease 22
phosphoenolpyruvate carboxykinase 21
papain 20
proteinase K 20
adenosine deaminase 20
phosphoenolpyruvate carboxykinase 20
aspartate aminotransferase 20
glutamine synthetase 20
phosphoenolpyruvate carboxykinase 19
tyrosinase 19
3C protease 19
adenosine deaminase 19
prostate-specific antigen 18
pyruvate kinase 18
kinesin 18
AMPK 17
ClpP 17
alcohol dehydrogenase 17
Lys4 17
NADH dehydrogenase 17
urease 17
PRE 17
lipase 17
NADPH oxidase 17
TAT 17
pyruvate dehydrogenase 16
thymidylate synthase 16
tyrosine hydroxylase 16
AMP-activated protein kinase 16
TOR 16
urease 15
glutamate dehydrogenase 15
phosphoinositide 3-kinase 15
succinate dehydrogenase 15
hydrogenase 15
glutamate dehydrogenase 15
hydrogenase 15
alpha-amylase 15
phospholipase A2 15
glutamate dehydrogenase 15
NADPH oxidase 14
SPC 13
cytochrome oxidase 13
histone demethylase 13
acid phosphatase 13
nucleoside triphosphate phosphohydrolase 13
rubisco 13
ubiquitin-protein ligase 13
IKK 13
aconitase 12
factor C 12
urokinase-type plasminogen activator 12
furin 12
venom phosphodiesterase 12
TGT 11
cellulase 11
peptidyl-prolyl cis-trans isomerase 11
guanylate cyclase 11
p80 11
protein phosphatase 2A 11
aspartate transcarbamylase 11
MAP 11
glutathione peroxidase 11
more...
Compound
DNA 12173
Dec 2525
ATP 946
lysine 651
serine 568
salt 509
phosphate 468
arginine 412
GTP 399
Clin 395
sodium 385
alanine 357
UTP 354
His 330
glucose 321
tyrosine 314
sulfate 310
cAMP 306
threonine 294
zinc 287
AMP 274
oxygen 269
calcium 268
nitrogen 265
uridine 262
TBP 248
TBP 248
pyrimidine 245
pyrimidine 245
Mg2+ 242
water 241
cysteine 241
methionine 240
leucine 231
Guo 223
SDS 221
DEAE 215
glycerol 212
hydrogen 210
tryptophan 199
ammonium 192
manganese 183
iron 181
acetate 176
Phe 167
galactose 159
CTP 157
Histone 132
proline 129
tryptophan 129
tryptophan 128
tryptophan 128
urea 127
Asp 126
Rifampicin 125
potassium 125
ADP 120
ADP 113
ADP 112
glutamate 109
NH2 108
nitric oxide 107
Gly 105
glutamine 105
bromide 104
ethanol 97
GMP 96
UMP 96
retinoic acid 90
ACS 88
ACS 88
TNF 87
Ile 82
copper 80
nitrate 73
EDTA 71
EDTA 70
tetraphosphate 69
acrylamide 68
CAM 67
silver 66
TAR 66
Nitrite 64
DRB 64
COS 63
NAD 62
MgCl2 58
PEG 56
CAT 53
isoleucine 53
CAT 53
valine 53
CAT 53
dATP 53
isoleucine 52
Optimal 51
formaldehyde 51
xylose 48
nickel 47
MTT 47
CAP 47
TTP 46
phenol 46
AAA 46
asparagine 46
GlcNAc 45
Actinomycin D 44
adenosylmethionine 44
DMS 44
mercury 44
glutamic acid 43
formaldehyde 43
CAP 43
40S 42
NAD 41
GAL 40
Insulin 40
Adenine 39
TIF 38
GDP 38
MIC 38
Triton X-100 38
PMA 37
guanidine 36
MDA 36
TOF 35
ABL 35
BCR 35
ammonia 34
vitamin D 34
aspartic acid 34
Estrogen 33
aspartic acid 33
aspartic acid 32
aspartic acid 32
Alanine 32
alpha-Amanitin 32
CO2 31
phosphoserine 31
Sucrose 31
barium 31
methanol 31
nicotinamide 31
acetic acid 31
Heparin 31
THP 30
TEM 30
PEG 30
cGMP 29
THP 29
Estrogen 29
NADH 29
CoA 29
dUTP 28
iodine 28
acridine 28
cadmium 27
PEP 27
PAM 26
A 3 26
more...