Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.7.49 (
reverse transcriptase
)
31,746
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Mol
2344
Sep
2204
cytokine
997
CD4
977
integrase
926
RNase H
843
pol
826
DNA polymerase
762
protease inhibitor
754
gag
485
interferon
458
tumor necrosis factor
419
telomeric
392
IL-6
391
tRNA
382
insulin
364
lymphoid
355
polypeptide
339
p24
337
collagen
331
env
313
IFN-gamma
312
lipopolysaccharide
310
IL-4
306
p66
304
IL-10
302
endonuclease
285
Gag
281
IL-2
278
ATP
270
interferon-gamma
269
Pol
265
ribonucleoprotein
262
p53
262
Gen
256
glycoprotein
239
p51
238
MT-4
232
TNF-alpha
228
cytochrome P450
220
p24 antigen
209
RNase
203
IL-8
201
thymus
200
CCR5
192
RNA-directed DNA polymerase
188
chemokine
188
CD8
180
IFN
179
fused
174
beta-actin
173
TNF
171
alkaline phosphatase
168
vascular endothelial growth factor
166
telomerase reverse transcriptase
162
inducible nitric oxide synthase
158
interleukin-6
156
Cytokine
153
tumor necrosis factor alpha
150
kit
148
tyrosine kinase
138
TGF-beta
136
nitric oxide synthase
135
NMR
135
Bcl-2
132
estrogen receptor
130
CD34
129
IL-1 beta
129
matrix metalloproteinase
129
SDS
128
HLA
127
P-glycoprotein
127
Polymerase
127
CXCR4
126
ABL
120
alternatively spliced
119
housekeeping
119
interleukin-2
118
interleukin-4
117
hTERT
117
more...
Disease
HIV
7899
immunodeficiency
3830
cancer
2375
AIDS
2292
tumor
1994
leukemia
1251
hepatitis B
611
carcinoma
486
breast cancer
418
virus infection
374
hepatocellular carcinoma
354
hepatitis C
340
myeloblastosis
339
influenza
327
acute myeloid leukemia
284
viremia
283
carcinogenesis
280
infectious diseases
276
lymphoma
276
tumorigenesis
272
metastases
261
chronic hepatitis
245
melanoma
239
diabetes
223
sarcoma
214
adenocarcinoma
206
chronic myeloid leukemia
198
Infection
193
CEM
191
prostate cancer
191
plaque
185
acute lymphoblastic leukemia
185
hepatitis
176
dengue
166
SARS
163
West
161
Human immunodeficiency virus type
154
tumor progression
149
squamous cell carcinoma
146
Leukemia
144
lung cancer
138
tuberculosis
137
rash
134
herpes simplex
133
SDS
132
colorectal cancer
131
avian influenza
131
MCF
130
anemia
129
neuroblastoma
128
Epstein
128
lipodystrophy
127
cirrhosis
123
cold
122
ABL
120
minimal residual disease
120
tumor growth
119
FTC
118
Mycobacterium
116
Rous sarcoma
114
gastric cancer
114
atherosclerosis
109
cytomegalovirus
107
acute promyelocytic leukemia
106
uterus
105
hypertension
104
gastroenteritis
103
ischemia
103
multiple myeloma
102
pneumonia
101
encephalitis
100
liver disease
95
Alzheimer's disease
92
glioma
92
colon cancer
90
lactic acidosis
84
mammary tumor
83
Hodgkin's disease
82
obesity
79
peripheral neuropathy
77
more...
Symptom
diarrhea
143
pain
102
starvation
52
headache
48
nausea
46
seizures
44
fatigue
41
cough
40
vomiting
36
respiratory distress
32
splenomegaly
29
weakness
26
dyspnea
23
abdominal pain
23
anesthesia
22
myalgia
21
anorexia
20
dizziness
19
collapse
14
Ill
14
ataxia
13
arthralgia
12
lethargy
11
tremor
11
wheezing
10
exhaustion
10
insomnia
10
hepatosplenomegaly
9
nasal discharge
9
acidity
9
dystonia
9
hypothermia
7
stigma
7
overweight
7
nausea and vomiting
7
hepatomegaly
7
flushing
7
rhinorrhea
6
discomfort
6
HSA
6
asthenia
6
sore throat
6
discomfort
6
emaciation
5
abdominal discomfort
5
thinning
5
functional recovery
5
chest pain
5
pallor
5
tachypnea
5
erythema
5
bitter taste
4
chills
4
paresthesia
4
anosmia
4
regurgitation
4
torticollis
4
myoclonus
4
photophobia
4
hyperoxia
4
back pain
4
incoordination
4
vertigo
4
low back pain
3
cachexia
3
ENT
3
shortness of breath
3
sneezing
3
paraparesis
3
Koplik spots
3
spasticity
3
paresis
3
angina
3
Hudson
3
analgesia
3
eds
3
blurred vision
2
acute stress
2
dysuria
2
Respiratory symptoms
2
more...
Drug
AZT
575
AZT
574
IFN-gamma
281
IL-2
280
Dermatol
253
PMPA
156
CSF
121
lysine
116
ddI
116
Tenofovir
86
EFV
71
Gel
70
NVP
64
Asn
61
Etravirine
59
PMEA
57
Truvada
54
Cardiovasc
53
ABC
47
DNase I
43
ROC
41
Tenofovir disoproxil fumarate
41
-deoxyadenosine
37
PFA
36
p75
33
Monit
33
TEL
31
MAP
28
G418
27
Angiotensin II
24
IFN-beta
24
ICI
24
Aztec
24
Raltegravir
23
Leaf
22
G-CSF
22
ATV
21
NADH
21
TAK
20
SPP
20
Enfuvirtide
19
ascorbate
19
ROS
18
Mutagen
18
Epivir
18
Entecavir
17
Entecavir
17
MRC
17
Indinavir
17
ETA
17
Activin
16
EE2
16
lactose
15
Bayer
15
TAT
15
NLF
15
Adefovir dipivoxil
15
Growth hormone
14
TAC
14
Kenyan
13
Imatinib
13
Growth hormone
13
Rescriptor
13
Alanine
13
DHT
12
ETS
12
ampicillin
12
ACT
11
caffeine
11
PTH
11
ENT
11
Norvir
10
PTC
10
uPA
10
Heme
10
Crixivan
10
Crixivan
10
Crixivan
10
vitamin E
10
Asthma
10
more...
Enzyme
reverse transcriptase
31746
DNA polymerase
1094
RNase H
952
RNA polymerase
516
RNase
345
transcriptase
335
RNase
323
ERK
306
endonuclease
285
focal adhesion kinase
236
mitogen-activated protein kinase
224
HIV-1 protease
220
luciferase
205
protein kinase
204
alkaline phosphatase
168
protein kinase C
129
P-glycoprotein
127
ribonuclease
126
ribonuclease
125
glyceraldehyde-3-phosphate dehydrogenase
110
DNase
102
glyceraldehyde-3-phosphate dehydrogenase
97
alanine aminotransferase
97
trypsin
95
ATPase
94
peroxidase
93
superoxide dismutase
85
collagenase
84
NO synthase
81
caspase-3
80
glutathione S-transferase
78
glyceraldehyde-3-phosphate dehydrogenase
78
CYP3A4
75
catalase
75
thymidine kinase
74
beta-galactosidase
72
glyceraldehyde-3-phosphate dehydrogenase
68
glyceraldehyde-3-phosphate dehydrogenase
68
S1 nuclease
66
renin
65
tyrosinase
62
neuraminidase
60
prostate-specific antigen
59
thrombin
59
proteasome
50
phospholipase C
50
aspartate aminotransferase
49
lactate dehydrogenase
48
ACS
47
phosphodiesterase
46
NOS
43
MEK
43
MIP
41
tyrosine hydroxylase
40
topoisomerase
39
adenylate cyclase
38
calcineurin
36
urokinase-type plasminogen activator
36
MMP
34
topoisomerase
34
NADPH oxidase
32
glutathione peroxidase
31
CD10
31
beta-glucuronidase
31
chymotrypsin
29
phospholipase A2
29
UDP-glucuronosyltransferase
28
adenosine deaminase
27
ACE
27
ribonucleotide reductase
27
chloramphenicol acetyltransferase
27
ribonucleotide reductase
27
MDR
26
NADPH oxidase
26
adenosine deaminase
26
cdc2
25
CD13
24
creatine kinase
24
laccase
24
MMP-3
23
more...
Compound
DNA
6437
Dec
2455
Clin
1365
AZT
673
calcium
495
water
490
3TC
372
sodium
367
phosphate
354
tyrosine
329
glucose
306
oxygen
304
tryptophan
300
lysine
279
ATP
273
d4T
257
sulfate
257
arginine
254
hydrogen
253
acetate
250
nitric oxide
232
methionine
207
TTP
203
alanine
201
cysteine
201
leucine
177
His
177
cAMP
175
salt
175
zinc
175
TNF
171
MTT
167
manganese
159
serine
156
bromide
153
retinoic acid
151
Nevirapine
145
Efavirenz
145
pyrimidine
143
pyrimidine
142
Mg2+
139
SDS
136
DEAE
136
threonine
133
iron
123
ABL
121
nitrogen
121
Phe
118
ethanol
115
glutamate
113
galactose
113
BCR
112
Asp
107
dUTP
102
COS
102
Ile
101
dGTP
94
Gly
92
dCTP
92
uridine
91
glycerol
84
GTP
80
potassium
80
AMP
80
dATP
77
copper
73
valine
73
tryptophan
73
methanol
72
ammonium
71
tryptophan
70
tryptophan
70
urea
66
iodine
65
proline
65
NH2
64
THP
63
THP
63
phenol
61
PEG
61
more...