Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.7.49 (
reverse transcriptase
)
31,746
document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Mol
2344
Sep
2204
cytokine
997
CD4
977
integrase
926
RNase H
843
pol
826
DNA polymerase
762
protease inhibitor
754
gag
485
interferon
458
tumor necrosis factor
419
telomeric
392
IL-6
391
tRNA
382
insulin
364
lymphoid
355
polypeptide
339
p24
337
collagen
331
env
313
IFN-gamma
312
lipopolysaccharide
310
IL-4
306
p66
304
IL-10
302
endonuclease
285
Gag
281
IL-2
278
ATP
270
interferon-gamma
269
Pol
265
ribonucleoprotein
262
p53
262
Gen
256
glycoprotein
239
p51
238
MT-4
232
TNF-alpha
228
cytochrome P450
220
more...
Disease
HIV
7899
immunodeficiency
3830
cancer
2375
AIDS
2292
tumor
1994
leukemia
1251
hepatitis B
611
carcinoma
486
breast cancer
418
virus infection
374
hepatocellular carcinoma
354
hepatitis C
340
myeloblastosis
339
influenza
327
acute myeloid leukemia
284
viremia
283
carcinogenesis
280
lymphoma
276
infectious diseases
276
tumorigenesis
272
metastases
261
chronic hepatitis
245
melanoma
239
diabetes
223
sarcoma
214
adenocarcinoma
206
chronic myeloid leukemia
198
Infection
193
CEM
191
prostate cancer
191
acute lymphoblastic leukemia
185
plaque
185
hepatitis
176
dengue
166
SARS
163
West
161
Human immunodeficiency virus type
154
tumor progression
149
squamous cell carcinoma
146
Leukemia
144
more...
Symptom
diarrhea
143
pain
102
starvation
52
headache
48
nausea
46
seizures
44
fatigue
41
cough
40
vomiting
36
respiratory distress
32
splenomegaly
29
weakness
26
dyspnea
23
abdominal pain
23
anesthesia
22
myalgia
21
anorexia
20
dizziness
19
Ill
14
collapse
14
ataxia
13
arthralgia
12
tremor
11
lethargy
11
exhaustion
10
wheezing
10
insomnia
10
hepatosplenomegaly
9
dystonia
9
nasal discharge
9
acidity
9
hepatomegaly
7
stigma
7
flushing
7
nausea and vomiting
7
hypothermia
7
overweight
7
asthenia
6
rhinorrhea
6
HSA
6
more...
Drug
AZT
575
AZT
574
IFN-gamma
281
IL-2
280
Dermatol
253
PMPA
156
CSF
121
ddI
116
lysine
116
Tenofovir
86
EFV
71
Gel
70
NVP
64
Asn
61
Etravirine
59
PMEA
57
Truvada
54
Cardiovasc
53
ABC
47
DNase I
43
Tenofovir disoproxil fumarate
41
ROC
41
-deoxyadenosine
37
PFA
36
p75
33
Monit
33
TEL
31
MAP
28
G418
27
IFN-beta
24
Angiotensin II
24
Aztec
24
ICI
24
Raltegravir
23
Leaf
22
G-CSF
22
ATV
21
NADH
21
TAK
20
SPP
20
more...
Enzyme
reverse transcriptase
31746
DNA polymerase
1094
RNase H
952
RNA polymerase
516
RNase
345
transcriptase
335
RNase
323
ERK
306
endonuclease
285
focal adhesion kinase
236
mitogen-activated protein kinase
224
HIV-1 protease
220
luciferase
205
protein kinase
204
alkaline phosphatase
168
protein kinase C
129
P-glycoprotein
127
ribonuclease
126
ribonuclease
125
glyceraldehyde-3-phosphate dehydrogenase
110
DNase
102
glyceraldehyde-3-phosphate dehydrogenase
97
alanine aminotransferase
97
trypsin
95
ATPase
94
peroxidase
93
superoxide dismutase
85
collagenase
84
NO synthase
81
caspase-3
80
glyceraldehyde-3-phosphate dehydrogenase
78
glutathione S-transferase
78
catalase
75
CYP3A4
75
thymidine kinase
74
beta-galactosidase
72
glyceraldehyde-3-phosphate dehydrogenase
68
glyceraldehyde-3-phosphate dehydrogenase
68
S1 nuclease
66
renin
65
more...
Compound
DNA
6437
Dec
2455
Clin
1365
AZT
673
calcium
495
water
490
3TC
372
sodium
367
phosphate
354
tyrosine
329
glucose
306
oxygen
304
tryptophan
300
lysine
279
ATP
273
d4T
257
sulfate
257
arginine
254
hydrogen
253
acetate
250
nitric oxide
232
methionine
207
TTP
203
cysteine
201
alanine
201
leucine
177
His
177
cAMP
175
zinc
175
salt
175
TNF
171
MTT
167
manganese
159
serine
156
bromide
153
retinoic acid
151
Nevirapine
145
Efavirenz
145
pyrimidine
143
pyrimidine
142
more...