Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.7.49 (reverse transcriptase)
 31,746 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Mol 2344
Sep 2204
cytokine 997
CD4 977
integrase 926
RNase H 843
pol 826
DNA polymerase 762
protease inhibitor 754
gag 485
interferon 458
tumor necrosis factor 419
telomeric 392
IL-6 391
tRNA 382
insulin 364
lymphoid 355
polypeptide 339
p24 337
collagen 331
env 313
IFN-gamma 312
lipopolysaccharide 310
IL-4 306
p66 304
IL-10 302
endonuclease 285
Gag 281
IL-2 278
ATP 270
interferon-gamma 269
Pol 265
p53 262
ribonucleoprotein 262
Gen 256
glycoprotein 239
p51 238
MT-4 232
TNF-alpha 228
cytochrome P450 220
p24 antigen 209
RNase 203
IL-8 201
thymus 200
CCR5 192
chemokine 188
RNA-directed DNA polymerase 188
CD8 180
IFN 179
fused 174
beta-actin 173
TNF 171
alkaline phosphatase 168
vascular endothelial growth factor 166
telomerase reverse transcriptase 162
inducible nitric oxide synthase 158
interleukin-6 156
Cytokine 153
tumor necrosis factor alpha 150
kit 148
tyrosine kinase 138
TGF-beta 136
NMR 135
nitric oxide synthase 135
Bcl-2 132
estrogen receptor 130
matrix metalloproteinase 129
CD34 129
IL-1 beta 129
SDS 128
Polymerase 127
HLA 127
P-glycoprotein 127
CXCR4 126
ABL 120
housekeeping 119
alternatively spliced 119
interleukin-2 118
hTERT 117
interleukin-4 117
gut 115
osteogenic 115
caspase-3 115
mer 115
Fas 115
IL-5 113
IL-1 113
BCR 112
DNA polymerase alpha 110
SARS 107
erythroid 105
CD44 102
endoplasmic reticulum 98
TERT 98
dimeric 98
lectin 95
fibronectin 92
transforming growth factor-beta 91
epidermal growth factor 91
growth hormone 89
granulocyte 89
osteocalcin 88
ORF 87
surface antigen 87
core protein 87
zinc finger 85
envelope glycoprotein 85
CSF 85
Pseudomonas 85
ATPase 83
p38 82
vimentin 81
DNA-dependent DNA polymerase 81
cryptic 80
major histocompatibility complex 80
UTR 78
MMP-9 77
interferon gamma 77
Poly 77
cytochrome 77
P450 76
p15 76
MT-2 76
angiotensin II 75
p30 75
envelope protein 75
CYP3A4 75
cytokeratin 74
thymidine kinase 74
p21 74
threonine 74
progesterone receptor 74
AMP 74
MMP-2 73
superoxide dismutase 73
T cell receptor 73
osteosarcoma 73
epidermal growth factor receptor 72
osteopontin 71
all-trans 71
olfactory 71
E-cadherin 71
alpha, beta 70
granulocyte-macrophage colony-stimulating factor 70
SIV 70
DNA polymerase beta 70
COX-2 70
SOD 70
CD14 70
LPS 69
leptin 69
RANTES 69
glyceraldehyde-3-phosphate dehydrogenase 68
AML1 68
insulin-like growth factor 68
glial fibrillary acidic protein 68
c-myc 67
tyrosinase 67
nerve growth factor 67
p27 67
more...
Disease
HIV 7899
immunodeficiency 3830
cancer 2375
AIDS 2292
tumor 1994
leukemia 1251
hepatitis B 611
carcinoma 486
breast cancer 418
virus infection 374
hepatocellular carcinoma 354
hepatitis C 340
myeloblastosis 339
influenza 327
acute myeloid leukemia 284
viremia 283
carcinogenesis 280
infectious diseases 276
lymphoma 276
tumorigenesis 272
metastases 261
chronic hepatitis 245
melanoma 239
diabetes 223
sarcoma 214
adenocarcinoma 206
chronic myeloid leukemia 198
Infection 193
prostate cancer 191
CEM 191
acute lymphoblastic leukemia 185
plaque 185
hepatitis 176
dengue 166
SARS 163
West 161
Human immunodeficiency virus type 154
tumor progression 149
squamous cell carcinoma 146
Leukemia 144
lung cancer 138
tuberculosis 137
rash 134
herpes simplex 133
SDS 132
colorectal cancer 131
avian influenza 131
MCF 130
anemia 129
Epstein 128
neuroblastoma 128
lipodystrophy 127
cirrhosis 123
cold 122
ABL 120
minimal residual disease 120
tumor growth 119
FTC 118
Mycobacterium 116
gastric cancer 114
Rous sarcoma 114
atherosclerosis 109
cytomegalovirus 107
acute promyelocytic leukemia 106
uterus 105
hypertension 104
gastroenteritis 103
ischemia 103
multiple myeloma 102
pneumonia 101
encephalitis 100
liver disease 95
glioma 92
Alzheimer's disease 92
colon cancer 90
lactic acidosis 84
mammary tumor 83
Hodgkin's disease 82
obesity 79
peripheral neuropathy 77
arthritis 77
multiple sclerosis 75
osteosarcoma 75
asthma 74
depression 71
measles 71
hepatitis A 70
bronchitis 70
STD 69
rheumatoid arthritis 69
bronchitis 69
non-small cell lung cancer 68
WT1 68
malaria 68
sepsis 67
Ewing's sarcoma 66
synovial sarcoma 64
PML 64
stomatitis 62
lymphadenopathy 62
glioblastoma 61
lipoatrophy 61
B-cell lymphoma 60
renal disease 60
cardiovascular disease 60
myelodysplastic syndrome 59
psoriasis 58
HTLV-I 58
acute leukemia 57
renal cell carcinoma 56
encephalomyelitis 56
cervical cancer 56
pertussis 55
sepsis 54
primary tumor 53
hepatitis E 53
lung carcinoma 53
viral diarrhea 53
respiratory infection 52
dementia 52
leukemogenesis 52
ovarian cancer 51
ARC 51
avian sarcoma 51
rhabdomyosarcoma 51
thrombocytopenia 50
SCID 50
SAR 49
neuropathy 49
osteoarthritis 49
herpes 49
Mycoplasma 48
adenoma 47
heart failure 47
type 2 diabetes 47
Newcastle disease 47
Melanoma 47
systemic lupus erythematosus 47
aggressiveness 47
vaccinia 46
avian leukosis 46
stroke 45
dyslipidemia 45
chronic lymphocytic leukemia 45
Kaposi's sarcoma 44
hyperglycemia 44
cystic fibrosis 43
bovine leukemia 43
SEM 43
TTP 42
dysplasia 42
TTP 42
pancreatitis 42
GSH 41
MIP 41
bladder cancer 41
respiratory disease 40
Schistosoma mansoni 40
retinoblastoma 40
myocardial infarction 40
more...
Symptom
diarrhea 143
pain 102
starvation 52
headache 48
nausea 46
seizures 44
fatigue 41
cough 40
vomiting 36
respiratory distress 32
splenomegaly 29
weakness 26
abdominal pain 23
dyspnea 23
anesthesia 22
myalgia 21
anorexia 20
dizziness 19
collapse 14
Ill 14
ataxia 13
arthralgia 12
tremor 11
lethargy 11
exhaustion 10
wheezing 10
insomnia 10
acidity 9
hepatosplenomegaly 9
nasal discharge 9
dystonia 9
nausea and vomiting 7
overweight 7
stigma 7
hypothermia 7
flushing 7
hepatomegaly 7
rhinorrhea 6
discomfort 6
HSA 6
asthenia 6
sore throat 6
discomfort 6
functional recovery 5
emaciation 5
chest pain 5
pallor 5
erythema 5
tachypnea 5
thinning 5
abdominal discomfort 5
chills 4
myoclonus 4
hyperoxia 4
incoordination 4
photophobia 4
paresthesia 4
anosmia 4
torticollis 4
regurgitation 4
bitter taste 4
back pain 4
vertigo 4
cachexia 3
ENT 3
paraparesis 3
Koplik spots 3
paresis 3
angina 3
spasticity 3
low back pain 3
shortness of breath 3
analgesia 3
sneezing 3
eds 3
Hudson 3
twitching 2
hypercapnia 2
Respiratory symptoms 2
decreased appetite 2
colic 2
nasal congestion 2
numbness 2
agitation 2
hemoptysis 2
exertional dyspnea 2
syncope 2
polyuria 2
cyanosis 2
DNA marker 2
skin irritant 2
tinnitus 2
sleepiness 2
dysuria 2
acute stress 2
blurred vision 2
cerebellar ataxia 2
flank pain 2
Neuropathic pain 2
astasia 2
generalized rash 1
POA 1
orofacial pain 1
Tissue anoxia 1
blepharospasm 1
hunger 1
Opiate withdrawal symptoms 1
Neurologic symptoms 1
bone pain 1
acute abdomen 1
skin irritation 1
meningism 1
non-productive cough 1
polydipsia 1
renal colic 1
dark urine 1
muscle cramps 1
adenitis 1
rigors 1
Asymptomatic hyperlactatemia 1
apathy 1
CSR 1
masculinization 1
ophthalmoplegia 1
chromosome marker 1
No adverse effect 1
staggering gait 1
constipation 1
clubbing 1
neck stiffness 1
dental pain 1
CNS symptom 1
rales 1
sciatica 1
enanthema 1
belching 1
abdominal fullness 1
rundown 1
fasciculation 1
abnormal gait 1
epigastric pain 1
respiratory problem 1
shoulder pain 1
phosphatemia 1
memory loss 1
Mills 1
distraction 1
disturbed balance 1
hypotonia 1
No toxic effect 1
musculoskeletal chest pain 1
Crushing 1
Drug
AZT 575
AZT 574
IFN-gamma 281
IL-2 280
Dermatol 253
PMPA 156
CSF 121
lysine 116
ddI 116
Tenofovir 86
EFV 71
Gel 70
NVP 64
Asn 61
Etravirine 59
PMEA 57
Truvada 54
Cardiovasc 53
ABC 47
DNase I 43
ROC 41
Tenofovir disoproxil fumarate 41
-deoxyadenosine 37
PFA 36
p75 33
Monit 33
TEL 31
MAP 28
G418 27
Aztec 24
Angiotensin II 24
IFN-beta 24
ICI 24
Raltegravir 23
G-CSF 22
Leaf 22
ATV 21
NADH 21
TAK 20
SPP 20
Enfuvirtide 19
ascorbate 19
ROS 18
Epivir 18
Mutagen 18
MRC 17
Entecavir 17
ETA 17
Indinavir 17
Entecavir 17
Activin 16
EE2 16
Bayer 15
TAT 15
lactose 15
Adefovir dipivoxil 15
NLF 15
TAC 14
Growth hormone 14
Kenyan 13
Rescriptor 13
Growth hormone 13
Imatinib 13
Alanine 13
ETS 12
DHT 12
ampicillin 12
ENT 11
caffeine 11
ACT 11
PTH 11
Heme 10
Crixivan 10
Retinoic acid 10
uPA 10
PTC 10
Norvir 10
Crixivan 10
Asthma 10
vitamin E 10
Crixivan 10
Truvada 9
Histamine 9
Glutathione 9
IL-11 9
Darunavir 9
Ziagen 9
Gleevec 9
Fragment 9
Paraffin 9
Viracept 9
Biopolymers 8
TMC114 8
Oseltamivir 8
ADR 8
Capsicum 8
KGF 8
Ethanol 8
Adriamycin 8
Acyclovir 8
Forskolin 8
Glycerol 7
CaCl2 7
Gelatin 7
RFP 7
CaCl2 7
Estrogens 7
Reverset 7
CTX 7
URF 7
Meth 7
CaCl2 7
Taxol 7
Maraviroc 7
nitroglycerin 6
R1881 6
Elvitegravir 6
CTC 6
Arsenic trioxide 6
RAL 6
Bifidobacterium 6
CPR 6
CAM 6
ADM 6
niacin 6
IL-1ra 6
Nephron 6
Albumin 6
Simvastatin 6
HPMPC 6
Fosamprenavir 5
Dial 5
Ginseng 5
Acacia 5
Emivirine 5
Fructose 5
Spectrum 5
CTC 5
Portal 5
DM1 5
CCL 5
TPV 5
Ranitidine 5
MDS 5
Mycophenolic acid 5
Kaletra 4
CTA 4
Fraction 4
Allergen 4
Isotretinoin 4
CTX 4
Pravastatin 4
Invirase 4
Artesunate 4
PCB 4
Glucagon 4
Agenerase 4
CPT-11 4
FAD 4
BLM 4
more...
Enzyme
reverse transcriptase 31746
DNA polymerase 1094
RNase H 952
RNA polymerase 516
RNase 345
transcriptase 335
RNase 323
ERK 306
endonuclease 285
focal adhesion kinase 236
mitogen-activated protein kinase 224
HIV-1 protease 220
luciferase 205
protein kinase 204
alkaline phosphatase 168
protein kinase C 129
P-glycoprotein 127
ribonuclease 126
ribonuclease 125
glyceraldehyde-3-phosphate dehydrogenase 110
DNase 102
alanine aminotransferase 97
glyceraldehyde-3-phosphate dehydrogenase 97
trypsin 95
ATPase 94
peroxidase 93
superoxide dismutase 85
collagenase 84
NO synthase 81
caspase-3 80
glutathione S-transferase 78
glyceraldehyde-3-phosphate dehydrogenase 78
catalase 75
CYP3A4 75
thymidine kinase 74
beta-galactosidase 72
glyceraldehyde-3-phosphate dehydrogenase 68
glyceraldehyde-3-phosphate dehydrogenase 68
S1 nuclease 66
renin 65
tyrosinase 62
neuraminidase 60
thrombin 59
prostate-specific antigen 59
proteasome 50
phospholipase C 50
aspartate aminotransferase 49
lactate dehydrogenase 48
ACS 47
phosphodiesterase 46
NOS 43
MEK 43
MIP 41
tyrosine hydroxylase 40
topoisomerase 39
adenylate cyclase 38
urokinase-type plasminogen activator 36
calcineurin 36
topoisomerase 34
MMP 34
NADPH oxidase 32
beta-glucuronidase 31
CD10 31
glutathione peroxidase 31
phospholipase A2 29
chymotrypsin 29
UDP-glucuronosyltransferase 28
ACE 27
ribonucleotide reductase 27
ribonucleotide reductase 27
adenosine deaminase 27
chloramphenicol acetyltransferase 27
adenosine deaminase 26
NADPH oxidase 26
MDR 26
cdc2 25
laccase 24
CD13 24
creatine kinase 24
dihydrofolate reductase 23
MMP-3 23
DNA ligase 22
phosphatidylinositol 3-kinase 22
PARP 22
DNA ligase 22
lipase 21
caspase-1 21
lysozyme 21
proteinase K 21
deoxycytidine kinase 21
guanylate cyclase 20
diaphorase 19
TdT 19
caspase-8 19
DNA methyltransferase 18
cytidine deaminase 18
lipoprotein lipase 17
glucose-6-phosphate dehydrogenase 17
phosphoglycerate kinase 17
granzyme B 17
APC 17
tissue plasminogen activator 17
plasmin 17
dUTPase 17
caspase-9 17
enolase 17
kallikrein 17
complex I 17
AMP-activated protein kinase 16
gamma-glutamyl transpeptidase 16
aldehyde dehydrogenase 16
thymidylate synthase 16
ornithine decarboxylase 16
elastase 16
MAP 15
furin 15
prostate-specific membrane antigen 15
cytochrome oxidase 15
glutamine synthetase 15
carbonic anhydrase 15
NQO1 15
hypoxanthine-guanine phosphoribosyltransferase 15
polynucleotide kinase 15
aldehyde dehydrogenase 15
matrix metalloproteinase 2 15
TAT 15
HSD 15
ATP synthase 15
AST 15
nitrogenase 14
cathepsin B 14
IMP dehydrogenase 14
pepsin 14
subtilisin 14
CPT 14
choline acetyltransferase 13
RNase T1 13
DCF 13
alpha-glucosidase 13
chitinase 13
deaminase 13
RNA ligase 13
matrix metalloproteinase 9 13
poly(A) polymerase 13
Alternating 13
GSK 12
citrate synthase 12
glutathione reductase 12
firefly luciferase 12
acetylcholinesterase 12
NADH dehydrogenase 12
cathepsin D 11
beta-glucosidase 11
CPT 11
microsomal epoxide hydrolase 11
aldehyde dehydrogenase 11
heme oxygenase 11
aldehyde dehydrogenase 11
CPT 11
neutrophil elastase 11
more...
Compound
DNA 6437
Dec 2455
Clin 1365
AZT 673
calcium 495
water 490
3TC 372
sodium 367
phosphate 354
tyrosine 329
glucose 306
oxygen 304
tryptophan 300
lysine 279
ATP 273
sulfate 257
d4T 257
arginine 254
hydrogen 253
acetate 250
nitric oxide 232
methionine 207
TTP 203
cysteine 201
alanine 201
His 177
leucine 177
cAMP 175
zinc 175
salt 175
TNF 171
MTT 167
manganese 159
serine 156
bromide 153
retinoic acid 151
Nevirapine 145
Efavirenz 145
pyrimidine 143
pyrimidine 142
Mg2+ 139
SDS 136
DEAE 136
threonine 133
iron 123
nitrogen 121
ABL 121
Phe 118
ethanol 115
glutamate 113
galactose 113
BCR 112
Asp 107
COS 102
dUTP 102
Ile 101
dGTP 94
Gly 92
dCTP 92
uridine 91
glycerol 84
AMP 80
potassium 80
GTP 80
dATP 77
copper 73
valine 73
tryptophan 73
methanol 72
ammonium 71
tryptophan 70
tryptophan 70
urea 66
iodine 65
proline 65
NH2 64
THP 63
THP 63
PEG 61
phenol 61
Abacavir 58
creatinine 58
acetonitrile 58
TMP 56
PMEA 52
cadmium 51
glutamine 51
MDA 49
cGMP 48
isoleucine 48
isoleucine 47
ACS 47
Insulin 47
GABA 46
GSH 46
GSH 46
HCl 45
ACS 44
GABA 44
Abbott 44
pyridine 43
silver 43
PMA 42
nickel 42
chloroform 42
UTP 41
thiourea 41
aspartic acid 39
DBA 39
aspartic acid 38
nitrate 38
aldosterone 37
BAL 37
Cardiol 37
pyrene 36
aspartic acid 35
NAD 35
aspartic acid 35
CO2 34
ADP 34
DBA 34
DAMP 34
ADP 34
Guo 34
Ang II 34
ADP 34
Pac 33
glutamic acid 33
DBA 33
NADPH 33
acetic acid 33
NADPH 33
Optimal 33
formaldehyde 33
DMP 32
TNM 32
phosphorus 32
TAR 32
PEG 32
EDTA 32
EDTA 32
DMP 31
Thyroid 31
H2O2 31
PMA 31
TEL 31
DMP 31
vitamin D 31
DMSO 31
DMP 31
5-HT 30
UDP 30
aldehyde 30
ammonia 30
Estrogen 29
asparagine 29
Collagen 27
Delavirdine 27
fluorine 27
Didanosine 27
more...