Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:2.7.7.49 (reverse transcriptase)
 31,746 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Partial transcripts of the homologues in cattle, of the genes encoding the NKR-P1 and NKG2-D natural killer cell lectin-like receptor families, were cloned by reverse transcriptase-PCR from bovine spleen. Three different cDNAs were partially sequenced for the NKG2-D homologue, and two for the NKR-P1 homologue. Identity to human nucleotide sequences was of 90 and 75%, respectively, and all structural residues of C-type lectin carbohydrate recognition domains were conserved. The identification of two of its members allows to hypothesise the existence of a bovine NK gene complex, prospectively located on chromosome 5.
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PMID:Homologues of natural killer cell receptors NKG2-D and NKR-P1 expressed in cattle. 1145 86