Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.7.49 (reverse transcriptase)
 31,746 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

At the 36th International Conference on Antimicrobial Agents and Chemotherapy (ICAAC), updates on research on non-nucleoside reverse transcriptase inhibitors, protease inhibitors, and newer treatments were presented. Among the research topics reviewed are results from the CAESAR study, guidelines for use of antiretrovirals, and the efficacy of new antiretroviral combinations. Also included are data tables showing the impact of viral load and CD4 count on risk of progression among 2,008 persons in trials of delavirdine; the detection of HIV RNA after 40 to 52 weeks in a trial of nevirapine/ZDV/ddI; viral load and CD4 changes in a phase I/II study of 141W94; viral load changes, principal side effects, and dropouts in a trial of ritonavir plus saquinavir; clinical endpoint results of the CAESAR trial; viral load and CD4 changes after 50 weeks of IL-2 plus indinavir; comparison of regimens for treating CMV retinitis; prevalence of Kaposi's sarcoma-associated herpesvirus antigen in HIV-positive and -negative groups; and rates of MAC bacteremia in ACTG 196/CPCRA 009, a trial comparing clarithromycin, rifabutin, and the combination for prophylaxis.
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PMID:Piloting the meanders of AIDS research. 1136 56