Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.7.49 (
reverse transcriptase
)
31,746
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Many adverse events have been described in patients treated with highly active antiretroviral therapy (HAART). Recently, among these,
adhesive capsulitis
of the shoulder has been described in some patients using protease inhibitors. We report our experience with 6 human immunodeficiency virus-positive patients in whom
adhesive capsulitis
of the shoulder developed during HAART. All 6 patients were treated with the same antiretroviral drug combination (HAART) including nucleoside
reverse transcriptase
(stavudine and lamivudine) and protease inhibitors (indinavir). The clinical pattern of
adhesive capsulitis
during HAART is similar to the classical form of
adhesive capsulitis
. Examining our case studies, we postulate a correlation between HAART and
adhesive capsulitis
. Discontinuation or reduction of the dosage of protease inhibitors associated with conventional conservative treatment is effective in reducing the symptoms and resolving the disease.
...
PMID:Adhesive capsulitis of the shoulder in human immunodeficiency virus-positive patients during highly active antiretroviral therapy. 1651 62
