Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.7.48 (transcriptase)
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Human Gene/Protein
trithorax homolog, Drosophila 11.7
NOPAR 11.7
LALP70 11.7
SRG5 11.7
cyclin-dependent kinase 2-interacting protein 11.7
EIF3S6IP 11.7
PDZ domain containing 7 11.7
nucleosomal binding protein 1 10.7
KLK15 protein 10.7
IQ motif containing GTPase activating protein 2 10.7
Polypeptide N-acetylgalactosaminyltransferase 14 10.7
CCDC60 10.7
integral membrane transporter protein 10.7
KLK12 protein 10.7
CCNE2 protein 10.7
feline leukemia virus subgroup C cellular receptor 1 10.7
B9D1 protein 10.7
DFNA5 protein 10.1
NADH-ubiquinone oxidoreductase chain 2 10.1
ZFP2 10.1
calpain 5 10.1
bone marrow zinc finger 3 10.1
BGPc 10.1
eukaryotic initiation factor 4AII 10.1
RFPL4 10.1
SS18/SSX2 fusion 10.1
MLL/AF6 fusion 10.1
BRCC2 10.1
PLCE1 protein 9.7
MPZL3 protein 9.7
GTF2H3 9.7
ADAM19 protein 9.7
myelin protein zero-like 2 9.7
ATP-dependent RNA helicase DDX3X 9.7
hPLD2 9.7
uridine-cytidine kinase 1 9.7
MRPS28 9.7
Int7 9.7
IGHEP1 9.7
kallikrein 12 9.7
HLA-C protein 9.7
myelin protein zero-like 3 9.7
deleted in esophageal cancer 1 9.7
TAP26 9.7
NOP5 9.7
COX7AL 9.7
Zinc finger protein A20 9.4
ubiquitin-like 5 9.4
NUP54 9.4
SYT/SSX1 fusion 9.4
PSMD8 9.4
polydom 9.1
myeloid ecotropic integration site 1 9.1
SSH6 9.1
inter-alpha-trypsin inhibitor heavy chain H1 9.1
LIX1 9.1
Chromodomain helicase DNA binding protein 5 9.1
nuclear RNA helicase 9.1
sperm ion channel 9.1
PABP4 9.1
DMXL1 9.1
LBP-9 9.1
ABC4 9.1
BGPa 9.1
mRNA (guanine-7-)methyltransferase 9.1
GDD 9.1
adenosine deaminase-like 8.9
ALR mRNA 8.9
3-OST-3 8.9
GalNAc-T14 8.9
VMA6 8.9
ADAMTS19 8.9
BLOC1S3 8.9
PN-II 8.9
ARSC 8.8
RDR 8.7
TRAPPC2 8.7
LTG9 8.7
HSPBAP1 8.7
Bcl-2-associated athanogene 5 8.7
more...
Disease
Benign mesenchymal neoplasms 10.7
Swine Disease 10.1
RP27 10.1
Boid inclusion body disease 9.9
GDD 9.7
Occult carcinoma 9.1
Venezuelan hemorrhagic fever 8.9
MDRV 8.7
MDC1D 8.5
Tumor embolus 8.5
PCH4 8.5
Spring viremia of carp 8.3
Paraneoplastic encephalomyelitis 8.3
DFNB18 8.1
Pleomorphic rhabdomyosarcoma 8.0
Border Disease 7.9
STL2 7.8
WNS 7.7
Essential mixed cryoglobulinemia 7.6
PCH1 7.5
Disseminated cancer 7.5
Infectious bursal disease 7.4
Bolivian hemorrhagic fever 7.3
Avian encephalomyelitis 7.3
GVM 7.2
Flavivirus infection 7.2
relapsed childhood ALL 7.2
Adynamic bone disease 7.1
viral leukemogenesis 7.1
Jembrana disease 7.0
DFNB31 7.0
SPG2 6.9
Ehlers-Danlos syndrome type VII 6.8
Viral Hemorrhagic Septicemia 6.8
Kyasanur Forest disease 6.8
DFNA5 6.8
Rinderpest 6.7
NS3 6.7
Rotavirus gastroenteritis 6.7
PCH2 6.7
Spindle epithelial tumor with thymus-like differentiation 6.7
WSN 6.5
WSN 6.5
Spondyloepiphyseal dysplasia tarda 6.5
NS2 6.5
Jaagsiekte 6.4
AB variant 6.3
JWS 6.3
Colorado tick fever 6.3
myeloblastosis 6.3
SPG1 6.3
Extrahepatic cholestasis 6.3
Clear cell sarcoma 6.3
Chikungunya virus infection 6.3
sandfly fever 6.2
Desmoplastic small round cell tumor 6.2
multiple nevi 6.2
Reflux nephropathy 6.2
Primary mediastinal large B-cell lymphoma 6.2
inv(X) 6.2
lipoprotein disorder 6.0
pulmonary carcinoid tumor 6.0
Dengue Shock Syndrome 6.0
viral diarrhea 6.0
Pontocerebellar hypoplasia 6.0
salivary gland adenocarcinoma 5.9
lipoatrophy 5.9
lyssavirus 5.8
Renal scarring 5.8
CMCT 5.8
Classical swine fever 5.8
Brill 5.8
Mouse hepatitis 5.8
stomatitis 5.7
Oligodendroglioma 5.7
Hand, foot, and mouth disease 5.7
Human rabies 5.7
Eosinophilic pustular folliculitis 5.7
Borna disease 5.7
Epithelioma 5.6
more...
Symptom
Opiate withdrawal symptoms 10.1
RNA marker 7.1
Ear swelling 5.7
Skin symptoms 5.6
CSR 4.9
loss of taste 3.2
muscle cramps 2.9
rundown 2.7
retching 2.6
nasal congestion 2.6
nasal discharge 2.3
sore throat 2.3
chest tightness 2.1
renal colic 2.1
diarrhea 2.0
wrist pain 2.0
myalgia 1.8
lethargy 1.8
sneezing 1.8
cough 1.8
joint stiffness 1.7
microbial colonization 1.7
hepatosplenomegaly 1.6
hypoproteinemia 1.6
rhinorrhea 1.6
wheezing 1.5
arthralgia 1.5
tachypnea 1.4
fasciculation 1.4
shortness of breath 1.4
asthenia 1.3
splenomegaly 1.3
cachexia 1.3
chills 1.2
bloating 1.0
epigastric pain 1.0
respiratory distress 0.9
acute pain 0.8
dyspnea 0.7
twitching 0.7
myoclonus 0.7
skin irritation 0.6
spasticity 0.6
Ill 0.6
starvation 0.6
ataxia 0.6
paresthesia 0.4
nausea 0.4
hyperoxia 0.4
vomiting 0.3
shoulder pain 0.3
dystonia 0.3
hepatomegaly 0.2
weakness 0.2
polyuria 0.1
colic 0.1
flushing 0.1
thinning -0.2
cyanosis -0.2
dysarthria -0.2
fatigue -0.4
functional recovery -0.4
anorexia -0.5
acute stress -0.5
distraction -0.5
collapse -0.5
acidity -0.6
headache -0.6
numbness -0.6
seizures -0.8
paresis -0.8
hypotonia -0.8
stigma -1.0
spasm -1.1
hypercapnia -1.2
overweight -1.4
tremor -1.5
nausea and vomiting -1.5
dizziness -1.5
low back pain -1.6
more...
Drug
Alovudine 10.5
Tribenoside 8.9
Lazabemide 8.7
Balhimycin 8.5
5-Fluorouridine 8.2
Capravirine 8.1
Tenofovir disoproxil fumarate 6.9
Gentian 6.7
ProstaScint 6.7
Tenofovir 6.6
Lonafarnib 6.5
Avilamycin 6.4
Pleconaril 6.4
PMPA 6.3
Raltegravir 6.2
Frovatriptan 5.9
Truvada 5.8
Kaletra 5.7
Telbivudine 5.4
Truvada 5.3
Etravirine 5.3
Domin 5.3
1,8-Cineole 5.2
Epivir 5.2
Valganciclovir 5.2
Maraviroc 5.2
Ddc 5.1
EFV 5.1
Crixivan 5.0
Crixivan 5.0
ddI 4.9
Entecavir 4.9
Entecavir 4.9
Intron A 4.9
Ara-A 4.9
Crixivan 4.9
TPV 4.8
Poudre 4.8
Indinavir 4.8
Adefovir dipivoxil 4.8
TEL 4.7
Intron A 4.7
Kelp 4.7
Intron A 4.6
Areca 4.6
Papain 4.6
AZT 4.6
Norvir 4.5
Darunavir 4.5
Dithranol 4.4
anti-RSV 4.4
AZT 4.4
Capsicum 4.4
GVG 4.4
Enfuvirtide 4.2
Dihydroergotamine 4.2
Carbenoxolone 4.1
Tween 40 4.1
R-gene 4.0
Aztec 4.0
Ramipril 3.9
IL-11 3.9
L-Ser 3.9
Adenosine deaminase 3.9
FCV 3.9
Fludarabine 3.8
Ammonium chloride 3.8
Swertia 3.8
KGF 3.8
NVP 3.8
Desferal 3.7
CDX 3.7
CTC 3.7
ETS 3.7
Geranium 3.7
Imiquimod 3.7
Nebivolol 3.7
Cidofovir 3.6
Desferal 3.6
Donepezil 3.6
more...
Enzyme
transcriptase 11.7
calpain 5 10.1
kallikrein 12 10.1
salutaridinol 7-O-acetyltransferase 9.4
phosphoglucokinase 9.4
RNA polymerase 9.1
ecdysone oxidase 8.5
salutaridine reductase 8.4
vanillate demethylase 8.1
coronavirus main proteinase 8.0
sterol glucosyltransferase 7.9
YdiB 7.7
NS protease 7.7
3C protease 7.0
phytanoyl-CoA hydroxylase 6.9
granzyme M 6.9
muconolactone isomerase 6.9
selenocysteine lyase 6.6
CMP kinase 6.4
HC-Pro 6.4
CMP-KDO synthetase 6.3
dihydrodipicolinate reductase 6.1
prolyl-tRNA synthetase 6.0
PGE2 isomerase 6.0
inositol dehydrogenase 6.0
TUT 6.0
site-1 protease 5.9
CPA2 5.9
sterol carrier protein 5.9
benzoate dioxygenase 5.8
carbamate kinase 5.8
RNase H 5.8
phosphoserine aminotransferase 5.7
collagenase 3 5.7
nucleoside triphosphate phosphohydrolase 5.7
RNA ligase 5.6
glycerate kinase 5.6
Mg-chelatase 5.6
2A protease 5.5
isoflavone reductase 5.4
glycine decarboxylase 5.4
poly(A) polymerase 5.3
muconate lactonizing enzyme 5.3
Protein 2 5.3
glycerophosphodiester phosphodiesterase 5.3
lysyl-tRNA synthetase 5.2
exoribonuclease 5.2
angiotensin-converting enzyme 2 5.2
retinol acyltransferase 5.2
reverse transcriptase 5.1
phosphomevalonate kinase 5.1
RNase PH 5.1
cystathionine beta-lyase 5.1
RNase III 5.0
triphosphatase 5.0
elongation factor (EF) 5.0
pyrrolysyl-tRNA synthetase 5.0
sucrose phosphorylase 5.0
adenylosuccinate synthetase 5.0
glutaminyl cyclase 5.0
nicotinamidase 4.9
aspartylglucosaminidase 4.9
site-1 protease 4.9
IMP dehydrogenase 4.9
alpha-methylacyl-CoA racemase 4.9
glutaminyl-tRNA synthetase 4.9
pyrroline-5-carboxylate dehydrogenase 4.9
LTC4 synthase 4.8
20alpha-hydroxysteroid dehydrogenase 4.7
catechol 1,2-dioxygenase 4.7
proline iminopeptidase 4.7
papain 4.7
myo-inositol-1-phosphate synthase 4.7
RNase 4.6
RNase 4.6
succinyl-CoA synthetase 4.6
tripeptidyl peptidase 4.6
deoxycytidine kinase 4.6
protocatechuate 3,4-dioxygenase 4.6
anthocyanidin synthase 4.5
more...
Compound
Macbecin I 10.7
(+)-Syringaresinol 10.1
Daphnoline 10.1
Salutaridine 9.7
DADI 9.7
5,6-dimethoxy-1-indanone 9.4
Robinin 9.4
Robinin 9.4
3-hydroxy-2-pyrazinecarboxamide 9.4
Trachelogenin 9.1
Delphinidin 3-glucoside 8.9
[1,2,4]triazolo[4,3-c]pyrimidine 8.9
AAFC 8.9
2-phenyl-1H-benzimidazole 8.9
C16H12O5 8.9
3-hydroxy-4H-pyran-4-one 8.7
ergosta-7,22-dien-3-one 8.7
Flumidin 8.7
1-benzothiophene-2-carboxamide 8.5
Balhimycin 8.5
Myrtenal 8.4
2-phenyl-1H-benzimidazole 8.4
Myrtenal 8.4
Kirromycin 8.2
DuP 697 8.1
1,3-benzenedisulfonic acid 8.0
1,3-benzenedisulfonic acid 8.0
GppppG 7.9
pyrido[2,3-b]pyrazine 7.7
2-mercaptobenzamide 7.7
Calanolide A 7.5
Quercetagetin 7.5
N-acetyl-glucosamine-1-phosphate 7.3
1H-pyrazolo[3,4-d]pyrimidine 7.3
Febrifugine 7.3
Linalyl acetate 7.3
8-azaspiro[4.5]decane-7,9-dione 7.2
DCL 7.2
Emtricitabine 7.0
Desthiobiotin 7.0
Ginkgetin 7.0
FUMP 6.9
Prednisolone acetate 6.8
8-Hydroxyguanine 6.8
Abacavir 6.7
CLTC 6.6
Chrome Azurol S 6.6
GIX 6.5
Sinigrin 6.5
Germin 6.4
Tricaine 6.4
Papaverine hydrochloride 6.3
9(10H)-anthracenone 6.3
beta-Lapachone 6.2
10-undecenoic acid 6.2
N-phenylbenzamide 6.2
10-undecenoic acid 6.2
Rifapentine 6.1
methylguanosine 6.1
Homocysteine thiolactone 6.1
Efavirenz 6.0
FUR 6.0
Coumermycin 5.9
T 12 5.9
bicyclo[2.2.1]heptane 5.9
TBO 5.9
Purine nucleoside 5.9
d4T 5.9
2-TCA 5.9
10-undecenoic acid 5.8
Gadolinium chloride 5.8
Anisodamine 5.7
Sepiapterin 5.7
UMP 5.7
W37 5.6
4-phenylbutanoic acid 5.6
kalinin 5.6
Valacyclovir 5.5
9(10H)-anthracenone 5.5
linoleoyl-CoA 5.5
more...