Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.7.48 (transcriptase)
 9,479 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 638
Mol 628
Gen 263
cytokine 262
helicase 241
polypeptide 227
interferon 199
methyltransferase 190
SARS 171
glycoprotein 157
ORF1 153
ATP 139
GTP 121
tumor necrosis factor 120
phosphoprotein 118
NS5 115
ras 113
Dicer 111
pol 107
ribonucleoprotein 105
PB1 104
fused 97
CD4 95
IL-6 86
lipopolysaccharide 85
collagen 85
tRNA 85
ORF 82
protease inhibitor 80
RNase 78
insulin 78
endonuclease 76
RNA helicase 76
unknown function 70
IL-4 69
UTR 68
VP2 67
IFN-gamma 67
IFN 64
interleukin-6 64
IL-10 63
lymphoid 61
Pol 60
interferon-gamma 60
serine protease 57
IL-2 56
p53 55
P protein 55
membrane-bound 55
TNF-alpha 54
integrase 53
endoplasmic reticulum 53
vascular endothelial growth factor 51
DNA polymerase 50
cryptic 50
matrix protein 49
NTP 49
inducible nitric oxide synthase 48
SDS 47
chemokine 47
ATPase 47
alternatively spliced 45
RACE 45
Polymerase 45
TNF 45
membrane protein 44
RNA polymerase II 44
IL-8 44
telomeric 44
nitric oxide synthase 44
thymus 44
NTPase 43
alkaline phosphatase 43
CD34 41
beta-actin 41
RNase H 41
tyrosine kinase 40
CTP 39
gut 38
gag 37
kit 37
HSP70 37
IL-5 36
AMP 36
core protein 36
caspase-3 35
NMR 34
histone 34
cysteine protease 34
neuraminidase 34
IL-1 beta 33
Cytokine 33
GDD 33
erythroid 32
Fas 32
fibronectin 32
TGF-beta 32
threonine 31
P-glycoprotein 30
telomerase reverse transcriptase 30
cytochrome P450 30
housekeeping 30
ubiquitin 30
interleukin-4 29
RNA polymerase I 29
CD8 29
BCR 28
angiotensin II 28
NS1 28
estrogen receptor 28
Bcl-2 27
ORF4 27
IL-1 26
stem cell factor 26
ABL 26
p13 26
epidermal growth factor 26
tumor necrosis factor alpha 26
osteogenic 25
proteasome 25
ribosomal protein 24
calcitonin 24
LPS 24
IL-3 24
GDP 24
glutathione S-transferase 24
carp 24
Pseudomonas 24
granulocyte 24
p21 23
dimeric 23
SOD 23
MLL 22
p24 22
EWS 22
matrix metalloproteinase 22
AML 22
bcl-2 21
HLA 21
TdT 21
Ang II 21
env 21
p11 21
microsomal 21
osteocalcin 21
Met 21
zinc finger 20
vasopressin 20
cytochrome 20
interleukin-2 20
renin 20
beta 1 20
vimentin 20
GMP 20
SAR 20
lectin 20
endothelin-1 20
major histocompatibility complex 20
EF-Tu 19
E-cadherin 19
more...
Disease
hepatitis C 498
cancer 485
influenza 402
HIV 396
tumor 392
immunodeficiency 274
virus infection 243
SARS 220
leukemia 164
AIDS 141
dengue 140
stomatitis 139
carcinoma 108
NS3 106
gastroenteritis 101
infectious diseases 99
hepatocellular carcinoma 87
West 84
hepatitis 76
breast cancer 75
acute myeloid leukemia 70
encephalitis 64
melanoma 64
lymphoma 61
chronic hepatitis 58
Infection 57
hepatitis B 57
plaque 54
avian influenza 52
mouth disease 52
measles 52
cirrhosis 52
metastases 52
pneumonia 51
rabies 51
chronic myeloid leukemia 51
viral diarrhea 50
viremia 48
SDS 47
carcinogenesis 47
hepatitis E 45
tumorigenesis 45
acute lymphoblastic leukemia 45
diabetes 44
cold 43
lung cancer 43
adenocarcinoma 41
Epstein 40
vaccinia 37
coxsackievirus 37
prostate cancer 36
gastric cancer 35
Japanese encephalitis 35
hemorrhagic fever 34
GDD 33
tumor progression 32
colorectal cancer 31
ischemia 31
sepsis 30
neuroblastoma 30
Mycobacterium 29
pertussis 28
yellow fever 27
Foot-and-mouth disease 26
squamous cell carcinoma 26
ABL 26
glioma 26
uterus 25
cytomegalovirus 25
tuberculosis 24
myositis 24
MCF 24
respiratory disease 24
chlorosis 23
anemia 23
minimal residual disease 23
Leukemia 23
multiple myeloma 23
Ewing's sarcoma 23
myeloblastosis 23
NS2 23
liver disease 23
sarcoma 23
herpes simplex 22
sepsis 22
bronchitis 21
asthma 21
bronchitis 20
Newcastle disease 20
Alzheimer's disease 20
SAR 20
acute leukemia 19
pancreatic cancer 19
ATM 19
WSN 19
obesity 19
rash 19
colon cancer 19
WSN 19
Infectious bursal disease 18
systemic lupus erythematosus 18
tumor growth 18
polymyositis 18
synovial sarcoma 18
glioblastoma 18
B-cell lymphoma 18
polio 17
dermatomyositis 17
lung carcinoma 16
acute promyelocytic leukemia 16
WT1 16
hepatitis A 16
lymphocytic choriomeningitis 15
renal cell carcinoma 15
interstitial lung disease 15
atherosclerosis 15
Rift Valley fever 15
hypertension 15
rheumatoid arthritis 15
renal disease 15
plague 15
eosinophilia 15
rhabdomyosarcoma 14
chronic lymphocytic leukemia 14
lactic acidosis 14
myopathy 14
SCID 14
lipodystrophy 14
thrombocytopenia 14
malaria 14
herpes 14
myocarditis 13
osteoarthritis 13
respiratory infection 13
chronic lymphocytic leukemia 13
leukemogenesis 13
Kaposi's sarcoma 13
chronic liver disease 13
osteosarcoma 13
dehydration 13
lipoatrophy 13
osteoporosis 13
encephalomyelitis 12
stroke 12
meningitis 12
mumps 12
choriocarcinoma 12
epididymis 12
adenoma 12
PML 12
cholera 11
myelodysplastic syndrome 11
retinoblastoma 11
lymphadenopathy 11
primary tumor 11
Crimean-Congo hemorrhagic fever 11
Burkitt's lymphoma 11
ovarian cancer 11
peritonitis 11
graft-versus-host disease 11
more...
Symptom
diarrhea 68
cough 25
pain 21
seizures 14
dyspnea 14
weakness 13
fatigue 12
vomiting 12
starvation 11
respiratory distress 11
headache 11
nausea 9
ataxia 7
splenomegaly 7
myalgia 7
collapse 6
lethargy 6
CSR 6
arthralgia 6
Ill 5
shortness of breath 4
sore throat 4
hepatosplenomegaly 4
anesthesia 4
cachexia 4
wheezing 4
anorexia 3
dystonia 3
functional recovery 3
chills 3
spasticity 3
abdominal pain 3
acidity 3
overweight 3
thinning 3
hyperoxia 2
hepatomegaly 2
distraction 2
tachypnea 2
analgesia 2
nasal discharge 2
rhinorrhea 2
flushing 2
muscle cramps 2
stigma 2
paresthesia 2
acute pain 2
asthenia 2
myoclonus 2
sneezing 2
nasal congestion 2
epigastric pain 2
angina 2
tremor 2
back pain 1
cyanosis 1
dizziness 1
Skin symptoms 1
acute stress 1
dysarthria 1
hypercapnia 1
joint stiffness 1
erythema 1
retching 1
spasm 1
Opiate withdrawal symptoms 1
rundown 1
paresis 1
low back pain 1
wrist pain 1
polyuria 1
fasciculation 1
loss of taste 1
Ear swelling 1
microbial colonization 1
skin irritation 1
hypoproteinemia 1
hypotonia 1
exhaustion 1
renal colic 1
chest pain 1
hypothermia 1
twitching 1
colic 1
nausea and vomiting 1
shoulder pain 1
chest tightness 1
numbness 1
RNA marker 1
Welt 1
bloating 1
Drug
lysine 66
IFN-gamma 59
IL-2 57
Dermatol 50
CSF 29
Gel 22
AZT 19
Cardiovasc 19
AZT 19
PMPA 18
Capsicum 14
Asn 12
Tenofovir 12
MAP 11
Leaf 11
ABC 10
caffeine 10
ETS 10
p75 9
DNase I 9
Angiotensin II 8
IFN-beta 8
Alanine 8
NADH 7
Biopolymers 7
ETA 7
nitroglycerin 7
ICI 7
Forskolin 6
ROC 6
TEL 6
-deoxyadenosine 6
Tenofovir disoproxil fumarate 6
IL-11 5
Nephron 5
Dial 5
Raltegravir 5
Gelatin 5
CTC 5
G418 5
MDS 5
Monit 4
Activin 4
NVP 4
ddI 4
Heme 4
Imatinib 4
EE2 4
CaCl2 4
CaCl2 4
Alovudine 4
TAT 4
Histamine 4
ZnCl2 4
ROS 4
lactose 4
ZnCl2 4
PTC 4
CaCl2 4
Papain 4
MRC 3
Truvada 3
Nephron 3
Bifidobacterium 3
Adenosine triphosphate 3
Adriamycin 3
Kenyan 3
ascorbate 3
Indomethacin 3
Adenosine deaminase 3
CTC 3
anti-RSV 3
Gleevec 3
Tacrolimus 2
Donepezil 2
Fludarabine 2
CDP 2
Entecavir 2
Ganciclovir 2
Luteinizing 2
Captopril 2
AraC 2
Imiquimod 2
Mutagen 2
vitamin E 2
Maraviroc 2
Triclosan 2
Itraconazole 2
Areca 2
pyridoxal phosphate 2
EFV 2
niacin 2
Entecavir 2
Estrogens 2
5-Fluorouridine 2
Growth hormone 2
G-CSF 2
Fraction 2
ACT 2
Growth hormone 2
KGF 2
PMEA 2
ALA 2
FAD 2
Indinavir 2
PFA 2
PCP 2
ADR 2
Ramipril 2
VCR 2
DMSA 1
Portal 1
Epivir 1
Dakar 1
Retinoic acid 1
Horizon 1
Carbenoxolone 1
Lonafarnib 1
Doxycycline 1
FCV 1
Acyclovir 1
DHT 1
Leucovorin 1
BH4 1
Guanidine 1
Glutamic acid 1
Capravirine 1
Darunavir 1
HPMPC 1
Check 1
TPV 1
Ranitidine 1
Taxol 1
Desferal 1
Artesunate 1
Geranium 1
Dihydroergotamine 1
CCL 1
Lazabemide 1
Rolipram 1
Mycophenolic acid 1
Truvada 1
ID2 1
Ddc 1
Papaverine 1
Atenolol 1
Crixivan 1
Fluorescein 1
Myricetin 1
Clonidine 1
CPR 1
AC2 1
Nitric Oxide 1
Bosentan 1
Erlotinib 1
Oseltamivir 1
citric acid 1
Crixivan 1
TAC 1
CAM 1
more...
Enzyme
transcriptase 9479
RNA polymerase 5737
reverse transcriptase 335
RNase 134
RNase 120
ERK 92
luciferase 83
DNA polymerase 78
endonuclease 76
protein kinase 71
ATPase 64
papain 51
focal adhesion kinase 50
mitogen-activated protein kinase 46
RNase H 46
alkaline phosphatase 43
protein kinase C 40
glutathione S-transferase 39
ribonuclease 38
neuraminidase 38
ribonuclease 38
trypsin 34
P-glycoprotein 30
proteasome 28
glyceraldehyde-3-phosphate dehydrogenase 27
catalase 27
NO synthase 26
collagenase 25
alanine aminotransferase 22
caspase-3 21
superoxide dismutase 21
renin 20
peroxidase 19
glyceraldehyde-3-phosphate dehydrogenase 19
3C protease 19
beta-galactosidase 19
CD10 19
DNase 17
thrombin 17
ACS 16
tyrosinase 16
glyceraldehyde-3-phosphate dehydrogenase 16
adenylate cyclase 16
aspartate aminotransferase 16
beta-glucuronidase 15
NADPH oxidase 15
firefly luciferase 15
chymotrypsin 15
triphosphatase 15
glyceraldehyde-3-phosphate dehydrogenase 14
lactate dehydrogenase 14
glyceraldehyde-3-phosphate dehydrogenase 14
phospholipase C 14
S1 nuclease 13
phosphodiesterase 13
NADPH oxidase 12
MEK 12
chloramphenicol acetyltransferase 12
DNA methyltransferase 12
ACE 11
APC 11
tyrosine hydroxylase 11
angiotensin-converting enzyme 2 11
phospholipase A2 11
RNA ligase 10
MMP-3 10
RNase III 10
creatine kinase 9
furin 9
SPC 9
micrococcal nuclease 9
NOS 9
poly(A) polymerase 8
exoribonuclease 8
HIV-1 protease 8
phosphatidylinositol 3-kinase 8
MMP 8
urokinase-type plasminogen activator 8
chitinase 8
CYP3A4 8
IMP dehydrogenase 8
MAP 7
prostate-specific antigen 7
CD13 7
granzyme B 7
arginase 7
proteinase K 7
ornithine decarboxylase 7
glycine decarboxylase 7
glutathione peroxidase 7
AST 6
5alpha-reductase 6
cdc2 6
matrix metalloproteinase 2 6
caspase-1 6
guanylate cyclase 6
PARP 6
PDE 6
5alpha-reductase 6
topoisomerase 6
thymidine kinase 5
sulfatase 5
adenosine deaminase 5
phosphoinositide 3-kinase 5
choline acetyltransferase 5
caspase-8 5
HC-Pro 5
pyruvate kinase 5
subtilisin 5
HSD 5
complex I 5
Protein 2 5
gamma-glutamyl transpeptidase 5
deoxycytidine kinase 5
lysozyme 5
hypoxanthine-guanine phosphoribosyltransferase 5
UDP-glucuronosyltransferase 5
topoisomerase 5
acid phosphatase 5
TAT 4
acetylcholinesterase 4
endothelin-converting enzyme 4
aldehyde dehydrogenase 4
phosphoglycerate kinase 4
hormone-sensitive lipase 4
aldehyde dehydrogenase 4
histidine decarboxylase 4
nitrate reductase 4
nitrate reductase 4
adenosine deaminase 4
peroxiredoxin 4
nitrate reductase 4
plasmin 4
chitin synthase 4
succinate dehydrogenase 4
nitrate reductase 4
NQO1 4
nitrate reductase 4
alcohol dehydrogenase 4
BMT 4
tissue plasminogen activator 4
PDK1 4
nitrate reductase 4
hyaluronidase 4
calcineurin 4
aldehyde dehydrogenase 4
aldehyde dehydrogenase 4
kallikrein 4
lipoxygenase 4
demethylase 4
thyroid peroxidase 4
TdT 4
aldehyde dehydrogenase 4
sialidase 4
Mg-chelatase 3
laccase 3
glucokinase 3
cathepsin K 3
cellulose synthase 3
DNA ligase 3
more...
Compound
DNA 1046
Dec 696
Clin 274
calcium 181
ATP 140
GTP 127
sodium 109
phosphate 107
alanine 104
arginine 100
water 99
tyrosine 93
serine 91
oxygen 88
lysine 83
salt 82
His 82
methionine 76
nitric oxide 72
cysteine 70
glucose 68
hydrogen 65
cAMP 64
UTP 62
leucine 61
Mg2+ 61
zinc 56
acetate 55
sulfate 54
manganese 53
SDS 49
uridine 46
TNF 45
Asp 44
threonine 43
glycerol 41
CTP 40
iron 40
pyrimidine 38
pyrimidine 38
glutamate 38
Gly 38
AMP 36
Phe 35
Ile 35
bromide 35
GMP 34
Guo 34
proline 33
retinoic acid 33
potassium 31
tryptophan 30
MTT 29
PEG 29
nitrogen 28
galactose 28
BCR 28
glutamic acid 26
ABL 26
COS 26
GDP 26
AZT 25
DEAE 24
Insulin 24
silver 23
copper 22
isoleucine 21
ammonium 19
urea 19
isoleucine 19
NH2 19
TTP 19
nitrate 19
3TC 18
salicylic acid 18
ethanol 18
Ang II 18
PEG 17
valine 17
UMP 17
cGMP 17
phenol 17
MDA 17
glutamine 16
Optimal 16
Triton X-100 16
Ribavirin 16
asparagine 16
ADP 16
ADP 16
tryptophan 15
ADP 15
tryptophan 15
tryptophan 15
nicotinamide 15
Angiotensin II 15
dUTP 15
THP 14
ACS 14
THP 14
aspartic acid 14
d4T 14
iodine 14
5-HT 14
acrylamide 14
ACS 14
methanol 13
aspartic acid 13
aspartic acid 13
ammonia 13
guanidine 13
PMA 13
aspartic acid 13
CAT 12
acetic acid 12
CO2 12
creatinine 12
CAT 12
Collagen 12
adenosylmethionine 12
CAT 12
adenylate 12
GSH 11
GSH 11
NADPH 11
UGA 11
NADPH 11
aldosterone 11
cadmium 10
Sucrose 10
PMA 10
40S 10
PGE 10
carbonate 10
caffeine 10
TEM 10
dATP 10
quinoline 9
quinoline 9
Cereb 9
EDTA 9
SAD 9
UDP 9
thiophene 9
gamma-aminobutyric acid 9
aldehyde 9
EDTA 9
TNM 9
TOF 9
UDP-glucose 9
CMP 8
cyanide 8
dGTP 8
homocysteine 8
HCl 8
A 3 8
ADP-ribose 8
CMP 8
chloroform 8
GABA 8
more...