Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.13.3 (
histidine kinase
)
2,405
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
DBX1
13.7
TMEM39B
13.7
HK1
13.7
RRG1
13.7
LOC400464
13.7
KIAA0746
12.7
branched chain alpha-ketoacid dehydrogenase kinase
12.7
HK3
12.2
TNFAIP2 protein
12.1
CDC42EP1
12.1
SYDE2
12.1
AK3L1
12.1
HK4
12.1
MFSD5
11.7
CDK5R2
11.7
PASKIN
11.5
ACTBL2
11.4
CDKL2
11.4
EPS8L2
11.4
HPT protein
11.4
HLR1
11.2
hexokinase 3
11.2
GAF1
11.1
FN3KRP
11.1
SLC25A23
11.1
CAF2
11.1
Bos1
11.0
HMG20B
10.9
HKR1
10.9
NKX2-6
10.9
Mak3p
10.5
kinase suppressor of ras
10.5
RCL1
10.5
MAN1A2
10.5
POTEE
10.5
HAMP
10.4
FNBP1L
10.4
PRKCDBP
10.4
MORC3
10.4
INHBC
10.4
SDF-2
10.1
CDC2L1
10.1
phosphohistidine phosphatase
10.1
DOK4
10.0
KLHL7
10.0
PPM2
10.0
PIK4CA
10.0
doublecortin kinase-2
9.9
STAC
9.8
CMT4C
9.8
RAPGEF3
9.8
HGN
9.8
EIF2S3
9.7
PABP-interacting protein 2
9.7
SLC2A8
9.6
FEM1B
9.6
CENP-Q
9.6
Spy1
9.6
SBF1
9.5
NPM3
9.5
HK2
9.5
OS4
9.5
Chp
9.5
AARS
9.4
THIK-2
9.4
TIG1
9.4
PSMC3
9.4
HADH
9.4
GLUT6
9.4
ATP5D
9.4
V-ATPase subunit A
9.3
PSMD1
9.3
RAB2A
9.3
hexokinase 1
9.3
TBCD
9.2
PFKP
9.2
KCNB1
9.2
SH3TC2
9.2
ARR1
9.2
HMGCL
9.2
FGD4
9.2
SPAG6
9.2
SLC6A6
9.1
EID1
9.1
DHTKD1
9.1
ALG8
9.1
ushA
9.0
GMP synthase
9.0
FMN2
9.0
GLUD1
9.0
KHK
9.0
RAB1A
9.0
RNF216
8.9
EIF2S1
8.9
ATP-dependent glucokinase
8.9
Sim
8.9
CNE1
8.9
SLC16A1
8.8
P76
8.8
GOT1
8.8
ALDOA
8.8
Histone H4
8.8
ALG2
8.8
ribosomal protein L6
8.8
SLC2A10
8.8
LASS2
8.7
MGB1
8.7
BPGM
8.7
GAF
8.7
TNFAIP2
8.7
PURA
8.7
PGAM1
8.7
MRAS
8.6
SMCHD1
8.6
Arnt
8.6
ALG6
8.6
SQLE
8.6
ENO2
8.6
Fructosamine-3-kinase
8.6
Barth syndrome
8.6
LAMR1
8.6
FOLH1
8.5
BAG2
8.5
porin
8.5
NAB1
8.5
PFKFB4
8.5
TPI1
8.5
TXNRD2
8.5
nucleoside diphosphate kinase
8.5
CIB
8.5
RARRES1
8.4
DPYSL2
8.4
GMP reductase
8.4
PSMA6
8.4
AKAP4
8.4
PDK3
8.4
EIF4G1
8.4
ARR2
8.4
TUBA1A
8.4
FAM3C
8.3
IL18R1
8.3
PRS I
8.3
metastasis suppressor protein
8.3
HPT1
8.3
ME3
8.3
Hexokinase
8.3
NDP kinase
8.3
PFKM
8.3
PRND
8.3
NCYM
8.3
hexokinase 2
8.3
CFL2
8.2
PKN1
8.2
GCK
8.2
Sorbitol dehydrogenase
8.2
ENO1
8.2
ATP synthase subunit beta
8.2
SLC2A5
8.2
DKK4
8.2
PMM2
8.2
more...
Disease
CMT4G
13.7
Hexokinase deficiency
13.7
CMT4D
12.0
CMT4C
10.4
Cyanotic congenital heart disease
9.6
trisomy 10p
9.6
TBCD
8.7
Nasopharyngeal carcinoma
7.7
Papillary renal cell carcinoma
7.5
CCA1
7.4
PCC
7.1
hereditary sensory neuropathy
6.9
Pemphigus foliaceus
6.7
Cohen syndrome
6.4
FHL2
6.3
gas gangrene
6.2
Papillomas
6.1
FALS
6.0
osteochondritis
5.9
Brucella abortus
5.8
pheochromocytoma
5.8
hereditary motor and sensory neuropathy
5.7
APOA1
5.6
PDC
5.6
crown gall
5.6
Silence
5.5
Giant cell tumor of bone
5.5
CAA
5.3
pneumonic plague
5.3
ERS
5.2
Liver regeneration
5.2
PER
5.1
FDH
5.0
bacillary dysentery
5.0
CAA
4.9
EPS
4.9
Brucella melitensis
4.9
hyperkeratosis
4.9
GBS
4.8
chemical carcinogenesis
4.8
community acquired pneumonia
4.8
CUP
4.8
EPS
4.7
ehrlichiosis
4.7
NPC
4.7
PHP
4.7
sporotrichosis
4.6
Mendelian disorders
4.6
profound mental retardation
4.6
lymphoepithelioma
4.4
AEM
4.4
familial hemophagocytic lymphohistiocytosis
4.4
urosepsis
4.3
Campylobacter infection
4.3
cholera
4.3
HIV disease progression
4.3
Yersinia
4.2
INS
4.2
RP4
4.2
Fox
4.2
MCS
4.2
papilloma
4.2
MCS
4.2
monocytic leukemia
4.1
systemic candidiasis
4.1
relapsing fever
4.1
CLN3
4.0
pseudotuberculosis
4.0
Bardet-Biedl syndrome
4.0
Legionella
3.9
rind
3.9
Lyme disease
3.9
RGS
3.9
bends
3.9
HTS
3.8
chancroid
3.8
musculoskeletal disease
3.8
Charcot-Marie-Tooth disease
3.7
melioidosis
3.7
keratosis
3.7
PAL
3.6
chlorosis
3.6
LDLR
3.6
FUS
3.5
Bordetella
3.4
laryngeal cancer
3.4
complex partial seizures
3.4
Malignancy
3.4
PIN
3.3
Mycobacterium
3.3
laryngeal cancer
3.3
MTS
3.3
anthrax
3.3
FMD
3.2
AAA
3.1
head and neck cancer
3.1
plant disease
3.0
Wells
3.0
Tay-Sachs disease
3.0
plague
3.0
SAD
3.0
erythroderma
3.0
latent infection
3.0
adrenocortical carcinoma
3.0
retinitis pigmentosa
2.9
tumor initiation
2.9
Epstein
2.8
AS1
2.8
skin tumor
2.8
NBS
2.8
lymphadenitis
2.8
Robinson
2.8
RSV infection
2.7
toxic shock syndrome
2.7
EBV infection
2.7
MLC
2.6
fungal infection
2.6
tooth loss
2.6
Schistosoma japonicum
2.6
tuberculosis
2.6
Neuroblastoma
2.6
Neuroblastoma
2.6
ADH
2.6
PDB
2.6
keratosis
2.6
typhoid
2.5
PIN
2.5
paracoccidioidomycosis
2.5
endometritis
2.5
tumor vasculature
2.5
SDS
2.5
MRSA
2.5
bacterial endocarditis
2.5
cystic fibrosis
2.4
aspergillosis
2.3
bacteremia
2.3
trisomy
2.3
chronic granulomatous disease
2.3
DDP
2.3
candidiasis
2.3
Cryptococcus neoformans
2.3
hepatoblastoma
2.3
Infections
2.3
enteritis
2.2
EMT
2.2
systemic disease
2.2
Still
2.2
Glioblastoma
2.2
tularemia
2.2
HCC
2.1
Shigella flexneri
2.1
dental caries
2.1
carcinogenesis
2.1
Klebsiella
2.1
skin cancer
2.1
CAP
2.1
gastrointestinal disease
2.1
tumorigenesis
2.1
brucellosis
2.0
NOD
2.0
more...
Symptom
scaly skin
6.3
twitching
5.3
starvation
4.4
general problem
3.9
microbial colonization
3.6
acidity
2.1
acute stress
1.5
hyperoxia
1.3
hypotonia
1.2
exhaustion
-0.0
tremor
-0.5
diarrhea
-0.5
angina
-0.7
dyspnea
-1.1
collapse
-1.1
weakness
-1.5
fatigue
-2.0
pain
-4.3
Drug
Whole human blood
9.4
TMX
7.4
Compound 19
7.2
Flavin
6.9
AraC
6.6
Flavopiridol
6.0
PE2
5.9
Tao
5.1
Doyle
5.0
beta-Galactosidase
4.9
Heme
4.9
OMP
4.8
DNase I
4.8
ABC
4.5
Colistin
4.3
Everolimus
4.3
Gefitinib
3.5
Arsenic trioxide
3.4
Honey
3.3
FeCl3
3.3
NaI
2.9
NaI
2.9
NaI
2.9
NaI
2.9
TTC
2.8
Asn
2.8
PCB
2.6
Gel
2.6
Capsicum
2.5
Glycerol
2.5
TAT
2.5
Fluorescein
2.3
FAD
2.3
Alanine
2.2
lysine
2.1
CaCl2
2.1
CaCl2
2.1
CaCl2
2.0
MRC
2.0
Fluorescein
1.8
p75
1.8
Glutathione
1.3
ampicillin
1.2
Bifidobacterium
1.2
lactose
0.7
Biopolymers
0.6
Nephron
0.6
Ethanol
0.4
NADH
0.3
MAP
-0.2
ROS
-0.5
caffeine
-0.7
Leaf
-0.7
IFN-gamma
-1.1
IL-2
-1.1
CSF
-1.2
Dermatol
-3.3
Enzyme
histidine kinase
13.7
choline-sulfatase
13.7
HK3
12.2
EC 5.4.99.15
11.4
5-methylthioribose kinase
10.7
citryl-CoA lyase
10.2
phosphoenolpyruvate-protein phosphotransferase
10.2
N5,N10-methenyltetrahydromethanopterin cyclohydrolase
10.0
SirA
9.6
ent-kaurenoic acid oxidase
9.5
HK2
9.5
K+-transporting ATPase
9.4
ketopantoate hydroxymethyltransferase
9.4
acetone carboxylase
9.4
GMP synthase
8.9
choline monooxygenase
8.6
acetylornithinase
8.4
GMP synthetase
8.0
GMP reductase
7.9
diacetyl reductase
7.8
trehalose synthase
7.6
C5a peptidase
7.4
STK3
7.3
glycerophosphodiester phosphodiesterase
7.3
CFA synthase
7.3
isopentenyltransferase
7.2
xyloglucanase
7.1
cystathionine beta-lyase
7.0
mutarotase
7.0
penicillin binding protein
7.0
arsenite oxidase
6.8
Escherichia coli exonuclease III
6.8
acetate kinase
6.8
MsrB
6.7
aspartokinase
6.6
citrate lyase
6.6
toluene dioxygenase
6.5
LuxS
6.5
pseudouridine synthase
6.4
hexokinase
6.4
cGMP phosphodiesterase
6.4
ACC oxidase
6.3
ScpA
6.3
PME
6.2
pyruvate formate-lyase
6.2
phosphoglyceromutase
6.1
Lod
6.1
endoproteinase Glu-C
6.0
glutamic dehydrogenase
5.9
PRT
5.9
glycerol dehydrogenase
5.9
ADE2
5.8
acylphosphatase
5.8
glycerol dehydrogenase
5.8
histidase
5.8
eEF2 kinase
5.8
formaldehyde dehydrogenase
5.8
clostripain
5.7
malate synthase
5.7
acyl-CoA thioesterase
5.6
pyruvate oxidase
5.6
pyruvate oxidase
5.6
GalT
5.5
dissimilatory sulfite reductase
5.5
serine racemase
5.5
TOR
5.5
LasR
5.5
Pla
5.5
MEKK1
5.4
sortase A
5.4
proline dehydrogenase
5.4
MsrA
5.3
sulfite reductase
5.3
sulfite reductase
5.3
levansucrase
5.3
ceramidase
5.3
sulfite reductase
5.3
Lys4
5.3
fatty acid desaturase
5.2
phosphomannose isomerase
5.2
fructokinase
5.2
hydrogenase
5.1
branched-chain alpha-keto acid dehydrogenase
5.1
hydrogenase
5.1
beta-xylosidase
5.1
transaldolase
5.0
ACC synthase
5.0
succinyl-CoA synthetase
5.0
methanol dehydrogenase
5.0
arginine kinase
4.9
acetyl-CoA synthetase
4.9
lysostaphin
4.8
formate dehydrogenase
4.8
formate dehydrogenase
4.8
lysyl endopeptidase
4.7
SCS
4.7
arginine decarboxylase
4.6
formate dehydrogenase
4.6
HtrA
4.6
estrogen sulfotransferase
4.6
serine hydroxymethyltransferase
4.5
arginine decarboxylase
4.4
cysteine synthase
4.4
fumarate reductase
4.4
polynucleotide kinase
4.3
RNA ligase
4.3
3-hydroxyacyl-CoA dehydrogenase
4.3
pectin methylesterase
4.2
glutamate synthase
4.1
lactic acid dehydrogenase
4.1
MCS
4.1
glutamate synthase
4.1
peptidyl-prolyl cis-trans isomerase
4.1
glutamate synthase
4.0
glyceraldehyde-3-phosphate dehydrogenase
4.0
PST
4.0
PTA
4.0
glycerol-3-phosphate dehydrogenase
3.9
glycerol-3-phosphate dehydrogenase
3.9
IMP dehydrogenase
3.9
chitin synthase
3.9
nitrate reductase
3.8
nitrate reductase
3.8
Rex
3.8
nitrate reductase
3.8
phosphodiesterase
3.8
GAS
3.8
glucokinase
3.8
acetyl-CoA carboxylase
3.8
cystathionine beta-synthase
3.8
nitrate reductase
3.8
ECH
3.7
PAL
3.6
sorbitol dehydrogenase
3.6
phosphoglycerate kinase
3.6
mitogen-activated protein kinase
3.6
PDK1
3.6
GRK5
3.6
fumarase
3.6
RNA polymerase
3.5
arylsulfatase
3.4
pectinase
3.4
RNase T1
3.4
nitrate reductase
3.4
nitrate reductase
3.4
CPS
3.4
cellulose synthase
3.4
chloramphenicol acetyltransferase
3.4
phosphofructokinase
3.4
acyl-CoA synthetase
3.4
transketolase
3.4
PCE
3.3
pyruvate kinase
3.3
SPC
3.3
peroxiredoxin
3.3
asparaginase
3.3
ATPase
3.3
dopamine beta-hydroxylase
3.2
phosphorylase
3.2
guanylate cyclase
3.2
more...
Compound
Fenpiclonil
12.1
Monorden
11.4
cdiGMP
10.7
Subtilin
10.6
Obacunone
9.9
Pyrrolnitrin
9.0
Closantel
9.0
Histidine
8.6
HOG
8.2
Foscan
8.0
Iprodione
8.0
Acetyl phosphate
7.5
Rifamycin
7.3
Rifamycin
7.3
PAS
7.2
Hypericin
7.1
Maltodextrin
7.0
Tazarotene
6.9
Phosphoserine
6.8
Oritavancin
6.7
Rifamycin
6.6
2-Deoxy-D-glucose
6.5
His
6.5
Flavin
6.4
Ethylene
6.4
TIB
6.4
DPS
6.2
Biliverdin
6.1
DGE
6.0
DGE
6.0
DGE
6.0
Daptomycin
6.0
Farnesol
5.9
PRD
5.9
PMB
5.8
G17
5.8
Digitonin
5.7
Rhein
5.6
Mannan
5.6
GMP
5.5
merocyanine 540
5.5
AAB
5.5
AAB
5.5
Na2S
5.5
Honokiol
5.4
TDT
5.3
CAA
5.3
Emodin
5.2
Safranin O
5.2
PTS
5.1
Pyrroloquinoline quinone
5.1
Asp
5.1
Ellagic acid
5.1
Thiocyanate
4.9
Procaine
4.8
PAPS
4.7
OMP
4.7
beta-D-galactoside
4.7
Heme
4.7
B17
4.6
carbamyl phosphate
4.5
glucose-6-phosphate
4.5
DBD
4.5
Arsenite
4.4
CHAPS
4.4
Cefotaxime
4.4
POP
4.4
NTA
4.4
phosphoserine
4.4
MCP
4.3
Methylglyoxal
4.3
Luteolin
4.3
1H-benzimidazole
4.3
aspartic acid
4.2
ATP
4.2
Methicillin
4.1
isonicotinic acid
4.1
homoserine
4.1
homoserine
4.1
threonine
4.1
homoserine
4.1
aspartic acid
4.0
MMA
4.0
aspartic acid
4.0
benzenesulfonamide
4.0
benzenesulfonamide
4.0
glycerol
4.0
benzenesulfonamide
4.0
MAD
4.0
Cysteine
4.0
phosphate
3.9
hydroxycinnamic acid
3.8
tetraphosphate
3.8
malic acid
3.8
malic acid
3.8
D-Ala
3.8
SAD
3.8
betaine
3.8
Ranitidine
3.8
malic acid
3.8
aspartic acid
3.8
FDP
3.8
asparagine
3.7
Collagenase
3.7
Hypo
3.7
serine
3.7
pentose
3.7
pentose
3.7
Genistein
3.7
Epigallocatechin gallate
3.6
pentose
3.6
phenylacetic acid
3.6
Melanin
3.6
phenylacetic acid
3.6
phenylacetic acid
3.6
RDX
3.6
DAP
3.6
DAP
3.6
pentose
3.6
malic acid
3.5
DCC
3.5
methyl methanesulfonate
3.4
phenylacetic acid
3.4
Berberine
3.4
PDB
3.4
chalcone
3.4
cysteine
3.4
PCE
3.4
MES
3.4
phosphoric acid
3.4
MES
3.4
Congo red
3.3
alanine
3.3
Mannitol
3.3
MTS
3.3
PEA
3.3
acetyl-CoA
3.3
Mannitol
3.3
1,3,5-triazine
3.2
1,3,5-triazine
3.2
Agarose
3.2
ABA
3.2
AAA
3.2
PCE
3.2
ETA
3.1
PIN
3.1
Quercetin
3.1
tert-butyl hydroperoxide
3.0
Prednisone
3.0
ADP
3.0
ADP
3.0
ADP
3.0
Biotin
3.0
isocitrate
3.0
isoleucine
3.0
isoleucine
2.9
MIC
2.9
UDP-GlcNAc
2.9
ABA
2.9
1H-imidazole
2.9
more...