Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.13.3 (
histidine kinase
)
2,405
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Mol
337
HK1
250
ATP
178
Sep
149
phosphatase
137
Pseudomonas
87
porin
86
NMR
65
membrane-bound
63
PCC
60
dimeric
57
membrane protein
48
ATPase
46
transcriptional regulator
39
fused
39
threonine
38
HAMP
38
hexokinase
32
GMP
31
HK2
30
GAF
30
nucleoside diphosphate kinase
27
Sim
26
MAP kinase
25
transcriptional activator
25
DNA-binding domain
24
MAPK
24
ADP
23
polypeptide
23
phosphorylating
22
SOD
22
ABC transporter
22
SDS
21
unknown function
20
Dictyostelium
20
phosphodiesterase
20
Arnt
19
DNase I
17
Gen
16
p53
16
ABC
15
nm23
15
AMP
15
GTP
15
adenylyl cyclase
15
insulin
14
DNA-binding protein
14
Hexokinase
13
ACS
13
hinge
12
adaptor protein
12
methyltransferase
12
ATP-binding cassette
12
transmembrane protein
12
MIC
12
GLUT1
11
tyrosine kinase
11
keratin
11
ARNT
11
gut
11
HK3
10
TCS
10
Barth syndrome
10
ras
10
histone H4
10
AKT
10
proteasome
9
CHK1
9
reductase
9
mTOR
9
MEK
9
integral membrane protein
9
cytoplasmic protein
9
SWI
9
transmembrane receptor
9
rhodopsin
9
serine/threonine kinase
9
hexokinase 2
9
alkaline phosphatase
9
PKM2
8
glucose transporter
8
mitogen-activated protein
8
catalase
8
MVA
8
PI3K
8
endoplasmic reticulum
8
leucine zipper
8
adenylate cyclase
8
PGM1
7
PKA
7
GCK
7
caspase-3
7
hexokinase 1
7
Bot
7
glucan
7
Cad
7
cGMP phosphodiesterase
7
glutathione S-transferase
7
A. nidulans
7
glycolytic enzyme
7
p21
7
histone
7
metastasis suppressor
7
interacting protein
7
novel gene
6
PTEN
6
CTR1
6
housekeeping
6
GAPDH
6
cyclin D1
6
calmodulin
6
cytokine
6
CNE1
6
NDP kinase
6
LMP1
6
peroxidase
6
Bos1
6
ENO1
6
LDHA
6
CAF2
5
like kinase
5
TOF
5
ESR
5
lipopolysaccharide
5
SIM
5
chimeric protein
5
MEKK
5
apoE
5
DNA gyrase
5
signal transduction protein
5
UCP2
5
LL-37
5
collagenase
5
Met
5
EGFR
5
metalloprotease
5
REC
5
TNF
5
KCa3.1
5
Hsp90
5
HNF4A
4
protein C
4
4E-BP1
4
CO2
4
GST
4
K14
4
CD4
4
spermatozoa
4
nm23-H1
4
serine protease
4
GBS
4
Pol
4
ubiquitin
4
tRNA
4
guanylate cyclase
4
Histone H4
4
ARR
4
heat shock protein 90
4
G6PD
4
glucose-6-phosphate dehydrogenase
4
more...
Disease
cancer
76
tumor
66
PCC
60
pheochromocytoma
60
Mycobacterium
40
carcinoma
36
tuberculosis
35
cholera
31
Nasopharyngeal carcinoma
28
cold
27
SDS
21
carcinogenesis
21
tumorigenesis
18
Yersinia
14
Brucella abortus
13
Epstein
13
breast cancer
11
infectious diseases
10
cystic fibrosis
10
Infection
9
Lyme disease
8
fungal infection
8
Legionella
8
Klebsiella
7
papilloma
7
hyperkeratosis
7
squamous cell carcinoma
7
tumor growth
7
pneumonia
7
plaque
6
melanoma
6
plague
6
pertussis
5
bacteremia
5
head and neck cancer
5
tumor progression
5
suicide
5
metastases
5
Bordetella
5
hypoglycemia
5
diabetes
5
hepatocellular carcinoma
5
dental caries
4
NPC
4
glioblastoma
4
bends
4
sepsis
4
gas gangrene
4
skin cancer
4
lung cancer
4
endocarditis
4
CAA
3
Cryptococcus neoformans
3
CMT4G
3
CMT4D
3
PER
3
colorectal cancer
3
PDC
3
aggressiveness
3
EPS
3
retinitis pigmentosa
3
sepsis
3
pseudotuberculosis
3
mental retardation
3
aspergillosis
3
CAA
3
Charcot-Marie-Tooth disease
3
Brucella melitensis
3
PDB
3
candidiasis
3
anthrax
3
gastric cancer
3
mental retardation
3
meningitis
3
coronary artery disease
3
B-cell lymphoma
3
primary tumor
3
Alzheimer's disease
3
Still
3
EPS
3
systemic disease
3
prostate cancer
3
Infections
3
chemical carcinogenesis
3
laryngeal cancer
2
crown gall
2
mastitis
2
lymphadenitis
2
periodontitis
2
neuroblastoma
2
trisomy 10p
2
liver cancer
2
DDP
2
neuropathy
2
Best
2
tumor initiation
2
latent infection
2
fatty liver
2
INS
2
colitis
2
ERS
2
ehrlichiosis
2
enteritis
2
HIV
2
adenocarcinoma
2
brucellosis
2
NOD
2
Fox
2
complex partial seizures
2
retinoblastoma
2
obesity
2
Proteus
2
typhoid
2
chlorosis
2
hyperglycemia
2
CMT4C
2
multiple myeloma
2
toxic shock syndrome
2
hereditary motor and sensory neuropathy
2
trisomy
2
virus infection
2
MTS
2
sporotrichosis
2
AAA
2
MRSA
2
CCA1
2
EBV infection
2
type 2 diabetes
2
SAR
2
abdominal aortic aneurysm
2
periodontal disease
2
ischemia
2
bladder cancer
2
dehydration
2
melioidosis
2
gastroenteritis
2
glioma
2
GBS
2
laryngeal cancer
2
glioblastoma multiforme
2
SEM
2
AEM
1
fibrosarcoma
1
pancreatic cancer
1
mole
1
Malignancy
1
Marfan syndrome
1
brain tumor
1
agranulocytosis
1
immune deficiency
1
plant disease
1
ABL
1
CUP
1
fits
1
urinary tract infection
1
HIV disease progression
1
mimicry
1
RGS
1
renal cell carcinoma
1
Schistosoma japonicum
1
more...
Symptom
starvation
41
twitching
6
acidity
5
diarrhea
3
microbial colonization
1
collapse
1
weakness
1
general problem
1
scaly skin
1
hyperoxia
1
acute stress
1
pain
1
fatigue
1
tremor
1
exhaustion
1
angina
1
hypotonia
1
dyspnea
1
Drug
lysine
19
DNase I
17
ABC
15
AraC
8
Gel
7
Heme
7
Asn
6
ampicillin
3
Flavin
3
CaCl2
2
Nephron
2
NADH
2
Dermatol
2
PCB
2
lactose
2
CaCl2
2
FAD
2
CaCl2
2
NaI
1
IL-2
1
Colistin
1
beta-Galactosidase
1
Alanine
1
Whole human blood
1
NaI
1
IFN-gamma
1
Gefitinib
1
Fluorescein
1
NaI
1
Fluorescein
1
TAT
1
OMP
1
Arsenic trioxide
1
Tao
1
TMX
1
CSF
1
Glutathione
1
TTC
1
Honey
1
Flavopiridol
1
Leaf
1
Everolimus
1
Compound 19
1
PE2
1
Capsicum
1
FeCl3
1
Biopolymers
1
NaI
1
Glycerol
1
ROS
1
caffeine
1
MRC
1
Ethanol
1
Doyle
1
p75
1
MAP
1
Bifidobacterium
1
Enzyme
histidine kinase
2405
mitogen-activated protein kinase
86
protein kinase
56
ATPase
47
hexokinase
33
HK2
30
RNA polymerase
30
phosphodiesterase
20
ACS
14
ERK
12
proteasome
12
glutathione S-transferase
11
HK3
10
adenylate cyclase
10
MEK
10
trypsin
10
alkaline phosphatase
9
catalase
9
hydrogenase
9
hydrogenase
9
glyceraldehyde-3-phosphate dehydrogenase
8
beta-galactosidase
7
guanylate cyclase
6
cGMP phosphodiesterase
6
tyrosinase
6
MEKK1
6
peroxidase
6
lactate dehydrogenase
5
glucose-6-phosphate dehydrogenase
5
TOR
5
calcineurin
5
urease
4
topoisomerase
4
SirA
4
nitrate reductase
4
cytochrome oxidase
4
luciferase
4
collagenase
4
phosphorylase
4
urease
4
nitrate reductase
4
APC
4
nitrate reductase
4
nitrate reductase
4
pyruvate kinase
4
acetate kinase
4
chloramphenicol acetyltransferase
4
focal adhesion kinase
4
reverse transcriptase
4
caspase-3
4
succinate dehydrogenase
3
alcohol dehydrogenase
3
GMP synthetase
3
topoisomerase
3
acetyl-CoA carboxylase
3
glutamate dehydrogenase
3
glucokinase
3
glutamate dehydrogenase
3
AMPK
3
PARP
3
penicillin binding protein
3
glutamate dehydrogenase
3
protein kinase C
3
nitrate reductase
3
superoxide dismutase
3
lipase
3
nitrate reductase
3
AMP-activated protein kinase
3
phosphofructokinase
3
carbonic anhydrase
3
aspartokinase
3
chitinase
3
LasR
3
DNase
3
glyceraldehyde-3-phosphate dehydrogenase
3
Pla
3
caspase-9
3
endoproteinase Glu-C
2
formate dehydrogenase
2
sulfatase
2
SCS
2
CAD
2
CAD
2
formate dehydrogenase
2
ACE
2
MAP
2
glyceraldehyde-3-phosphate dehydrogenase
2
formate dehydrogenase
2
CAD
2
laccase
2
CaMKII
2
PME
2
glyceraldehyde-3-phosphate dehydrogenase
2
glycerol-3-phosphate dehydrogenase
2
malate synthase
2
PDK1
2
MsrB
2
nitrogenase
2
glycerol-3-phosphate dehydrogenase
2
xylanase
2
PTA
2
asparaginase
2
deaminase
2
complex I
2
chymotrypsin
2
proteinase K
2
malate dehydrogenase
2
cellulase
2
fatty acid desaturase
2
xylanase
2
beta-glucuronidase
2
citrate lyase
2
ACC oxidase
2
glyceraldehyde-3-phosphate dehydrogenase
2
LuxS
2
pectinase
2
phosphoglycerate kinase
2
arginase
2
trehalose synthase
2
pyruvate dehydrogenase
2
PAL
2
GMP synthase
2
creatine kinase
2
peroxiredoxin
2
SPC
2
arginine kinase
1
toluene dioxygenase
1
phosphoenolpyruvate-protein phosphotransferase
1
branched-chain alpha-keto acid dehydrogenase
1
ECH
1
phospholipase C
1
phytase
1
glutaminase
1
succinic dehydrogenase
1
acyl-CoA synthetase
1
TAT
1
CPS
1
fumarase
1
glycerophosphodiester phosphodiesterase
1
pseudouridine synthase
1
pyruvate dehydrogenase
1
C5a peptidase
1
cystathionine beta-synthase
1
adenylate kinase
1
acetone carboxylase
1
N5,N10-methenyltetrahydromethanopterin cyclohydrolase
1
RNA ligase
1
PRT
1
kallikrein
1
arylsulfatase
1
prostate-specific membrane antigen
1
choline-sulfatase
1
glutamate synthase
1
IKK
1
glutamate synthase
1
succinyl-CoA synthetase
1
Escherichia coli exonuclease III
1
glutamic dehydrogenase
1
elastase
1
IMP dehydrogenase
1
more...
Compound
His
530
DNA
279
phosphate
195
ATP
178
Dec
163
oxygen
111
glucose
93
Asp
89
nitrogen
73
PAS
69
serine
64
cysteine
59
threonine
56
alanine
54
tyrosine
51
glycerol
49
Histidine
44
water
43
hydrogen
42
iron
40
salt
37
arginine
35
GMP
32
lysine
29
ADP
26
nitrate
25
acetate
25
calcium
24
leucine
24
cAMP
24
ADP
23
ADP
23
SDS
21
glutamate
21
sulfate
21
sodium
20
copper
18
nitric oxide
17
galactose
16
aspartic acid
16
Ethylene
16
AMP
15
potassium
15
zinc
15
GTP
15
proline
14
aspartic acid
13
aspartic acid
13
aspartic acid
13
ACS
13
ACS
13
asparagine
12
Mg2+
12
MIC
12
HOG
12
Gly
11
ethanol
11
Clin
11
tryptophan
11
tryptophan
10
H2O2
10
tryptophan
10
NH2
10
tryptophan
10
methionine
9
PEG
9
glutamine
9
urea
9
Ile
9
Phe
8
phosphoric acid
8
CO2
8
ammonium
8
manganese
8
Heme
7
ammonia
7
valine
7
pentose
6
xylose
6
isoleucine
6
cyanide
6
pentose
6
isoleucine
6
pentose
6
glucose-6-phosphate
6
pentose
6
TOF
5
TNF
5
betaine
5
acetyl-CoA
4
Cysteine
4
PEG
4
nickel
4
Methicillin
4
NAD
4
homoserine
4
NTA
4
boron
4
cadmium
4
NAD
4
MDA
4
GDP
4
MTT
4
phosphoserine
4
Subtilin
4
homoserine
4
homoserine
4
methanol
4
L-DOPA
3
BCG
3
UDP
3
Congo red
3
Hypericin
3
phenol
3
PDB
3
ABA
3
Insulin
3
MMA
3
cGMP
3
Flavin
3
NADPH
3
silver
3
CoA
3
toluene
3
adenylate
3
glutamic acid
3
CAA
3
NADPH
3
ABA
3
Emodin
3
MCP
3
Daptomycin
3
Triton X-100
2
hydroxycinnamic acid
2
Tyrosine
2
GSH
2
Phytol
2
GAL
2
Phytol
2
Lactate
2
AAA
2
MTS
2
ETA
2
DCC
2
NADP
2
malic acid
2
THP
2
Closantel
2
GSH
2
GABA
2
GABA
2
POP
2
Curcumin
2
CBS
2
chalcone
2
TIB
2
FAD
2
Foscan
2
TPA
2
cobalt
2
more...