Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.12.2 (
MEK
)
18,161
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
MEK
12715
ERK
6082
MEK1
4168
MAPK
3532
ERK1
3500
p38
2355
Mol
2007
BRAF
1876
extracellular signal-regulated kinase
1837
PI3K
1658
MAP kinase
1470
JNK
1385
mitogen-activated protein
1274
Sep
1250
AKT
1116
RAF
969
mTOR
880
Raf-1
860
c-Jun
840
ERK2
797
tyrosine kinase
779
MKK4
692
cytokine
689
phosphatidylinositol 3-kinase
687
PKC
549
insulin
537
epidermal growth factor
528
KRAS
514
caspase-3
504
EGFR
503
p53
502
epidermal growth factor receptor
492
p42
482
MKK6
442
Bcl-2
436
MAP
435
AP-1
435
p44
426
MEK2
419
phosphatase
417
MEKK
382
threonine
379
MKK7
375
EGF
360
p21
355
ATP
325
MKK3
324
extracellular signal-regulated kinase 1
324
JNK1
323
tumor necrosis factor
316
cyclin D1
293
p38 mitogen-activated protein kinase
285
phosphoinositide 3-kinase
275
STAT3
272
collagen
271
NRAS
271
p38 MAP kinase
269
IL-6
267
PI3
251
TNF
250
ras
247
PKA
245
NS5
241
vascular endothelial growth factor
238
EGF receptor
230
c-fos
230
lipopolysaccharide
223
protein kinase B
216
Rho
215
CREB
205
PTEN
202
GTP
201
nerve growth factor
197
receptor tyrosine kinase
196
STAT
181
platelet-derived growth factor
179
matrix metalloproteinase
179
proteasome
176
p65
174
MEKK1
174
VEGF
174
MAP2K1
168
IL-8
167
fibronectin
165
E-cadherin
163
TNF-alpha
162
catenin
162
estrogen receptor
152
calmodulin
151
cyclooxygenase-2
150
PARP
148
MMP-9
148
cytochrome c
145
chemokine
145
HER2
143
LPS
142
angiotensin II
142
p38MAPK
140
Mcl-1
139
PDGF
139
serine/threonine kinase
138
p27
137
ROS
133
COX-2
133
PP2
133
H-ras
132
AMP
132
GSK
131
interleukin-6
129
cyclin
126
GTPase
126
c-Src
125
JAK2
125
JNK2
125
endoplasmic reticulum
123
RhoA
121
Ang II
121
c-Myc
120
focal adhesion kinase
119
brain-derived neurotrophic factor
118
ribosomal S6 kinase
118
TGF-beta
117
caspase-9
116
phosphorylating
116
PKB
116
nitric oxide synthase
114
inducible nitric oxide synthase
113
MMP-2
112
ubiquitin
111
hepatocyte growth factor
111
insulin-like growth factor
109
THP
109
PLC
108
FGF
107
extracellular signal regulated kinase
107
VEGFR2
106
FAK
104
PIK3CA
103
MAPK/ERK kinase
103
histone
102
protein phosphatase
102
CDK4
102
PI3-kinase
101
IFN
100
MET
100
Fas
100
PP1
99
p90
99
interferon
98
PD-1
98
histone deacetylase
96
B-RAF
94
caspase-8
94
TLR4
94
IKK
93
Cytokine
91
insulin receptor
91
cyclooxygenase
90
ATPase
89
ERK5
89
mitogen-activated protein kinase kinase 1
89
thrombin
89
ASK1
89
PD-L1
87
protein kinase C inhibitor
86
Sp1
86
S6K1
86
BOD
83
proto-oncogene
83
adaptor protein
82
G protein-coupled receptor
82
GSH
82
RSK
81
IkappaBalpha
80
small GTPase
79
HRAS
79
IL-2
78
neurotrophin
77
calcineurin
77
protein tyrosine kinase
77
IRS-1
77
vimentin
76
cyclin E
76
STAT5
76
urokinase-type plasminogen activator
76
adenylyl cyclase
76
TAK1
75
KIT
75
CD4
74
endothelin-1
73
IGF-I
72
adenylate cyclase
72
Smad2
72
cyclin-dependent kinase
72
CTLA-4
72
metalloproteinase
71
CA1
70
MKP-1
70
catalase
70
erythroid
69
survivin
69
IGF-1
69
NGF
68
IL-10
68
annexin V
68
MEK5
67
IL-1
67
GSK3
67
axonal
67
STAT1
66
IL-4
66
ALK
66
erbB-2
66
p70
66
p50
65
tumor necrosis factor alpha
65
p85
65
14-3-3
65
4E-BP1
65
CaMKII
65
NF1
64
beta-catenin
64
osteosarcoma
64
lymphoid
63
MMP9
63
signal transducer and activator of transcription 3
62
SHP-2
62
eIF4E
61
ATF
61
alkaline phosphatase
61
TPA
61
p70 S6 kinase
61
myelin basic protein
60
proteasome inhibitor
60
ribosomal protein S6
60
phospholipase
60
neuregulin
60
interacting protein
60
cyclin A
59
gut
59
leptin
59
osteogenic
59
tyrosine phosphatase
59
proliferating cell nuclear antigen
59
N-cadherin
58
PI-3 kinase
58
MMP
58
Smad3
58
BCL2
58
BCR
58
peroxisome proliferator-activated receptor gamma
58
CD44
58
p16
57
AMPK
57
IFN-gamma
57
CD8
57
MMP-1
57
PP2A
57
c-myc
57
protein kinase 2
56
macrophage colony-stimulating factor
56
polypeptide
55
P38
55
Epidermal growth factor
55
IkappaB kinase
55
K-ras
55
NMDA receptor
54
glycoprotein
54
superoxide dismutase
54
FGF2
54
GST
54
CD11b
54
CXCR4
54
CCL2
54
WAF1
53
RET
53
Rho kinase
53
arrestin
53
fused
53
A431
52
ABL
52
PTPN11
52
MCP-1
52
Elk1
51
TCR
50
Met
50
SRC
50
AMP-activated protein kinase
50
type I collagen
50
Nrf2
50
platelet-derived growth factor receptor
49
LC3
49
MYC
49
protein tyrosine phosphatase
49
Tumor necrosis factor
49
cyclin B1
48
AP1
48
peroxisome proliferator-activated receptor
48
BAX
48
UTR
48
IL-3
48
cAMP response element-binding protein
47
interleukin-2
47
JNK3
47
histone H3
47
SEK
47
c-Met
47
CDK2
46
Leukemia inhibitory factor
46
PD1
46
XIAP
46
HEK
46
MLK3
46
mitogen-activated protein kinase kinase kinase
46
lactate dehydrogenase
45
cAMP-dependent protein kinase
45
PDK1
45
EBP
45
GM-CSF
45
ADP
45
more...
Disease
cancer
3808
tumor
2660
melanoma
1296
breast cancer
600
tumor growth
563
tumorigenesis
552
carcinoma
419
hepatocellular carcinoma
360
leukemia
356
metastatic melanoma
349
lung cancer
349
colorectal cancer
332
carcinogenesis
318
tumor progression
305
adenocarcinoma
275
metastases
249
pertussis
243
non-small cell lung cancer
226
Melanoma
224
MCF
213
colon cancer
211
prostate cancer
201
ischemia
191
pancreatic cancer
187
neuroblastoma
173
glioma
168
acute myeloid leukemia
158
ovarian cancer
157
squamous cell carcinoma
145
atherosclerosis
142
diabetes
140
Alzheimer's disease
131
gastric cancer
127
hypertension
118
multiple myeloma
116
Blocking
109
glioblastoma
101
Parkinson's disease
99
obesity
97
skin cancer
96
lymphoma
88
retinoblastoma
87
pheochromocytoma
84
lung carcinoma
83
chronic myeloid leukemia
83
sarcoma
83
GSH
82
Leukemia
80
thyroid cancer
79
anthrax
79
cerebral ischemia
73
ATM
73
liver cancer
73
osteosarcoma
70
stroke
65
heart failure
65
rheumatoid arthritis
63
depression
61
liver cancer
60
epithelial ovarian cancer
60
asthma
59
HIV
59
virus infection
59
infectious diseases
55
cutaneous melanoma
55
acute lymphoblastic leukemia
55
tumor angiogenesis
54
primary tumor
52
renal cell carcinoma
52
ABL
52
astrocytoma
48
neoplastic transformation
47
acute promyelocytic leukemia
46
Infection
46
aggressiveness
45
neurofibromatosis type 1
44
fibrosarcoma
44
B-cell lymphoma
42
Hepatocellular carcinoma
42
AGS
42
cold
42
type 2 diabetes
42
HGF
41
osteoporosis
40
papillary thyroid cancer
40
influenza
40
osteoarthritis
40
NAME
39
EMT
38
cervical cancer
38
hyperglycemia
38
APC
38
plaque
38
bladder cancer
37
Langerhans cell histiocytosis
36
immunodeficiency
36
addiction
34
glioblastoma multiforme
34
mole
33
brain tumor
33
rash
33
cardiovascular disease
33
sepsis
33
SCID
33
brain metastases
33
colitis
32
myocardial infarction
32
SDS
32
sepsis
32
tumor initiation
30
chronic lymphocytic leukemia
30
hepatitis C
30
hematologic malignancies
29
herpes simplex
29
solid tumor
28
myeloid leukemia
28
Costello syndrome
28
arthritis
28
myeloproliferative disorders
27
chronic lymphocytic leukemia
27
anaplastic thyroid cancer
27
leukemogenesis
27
uveal melanoma
27
Mycobacterium
26
polycystic kidney
26
endometrial cancer
26
chondrosarcoma
26
esophageal cancer
26
stage IV melanoma
25
Adhesion
25
Osteosarcoma
25
cholera
25
Osteosarcoma
25
tuberous sclerosis
24
amyotrophic lateral sclerosis
24
esophageal cancer
24
diabetic nephropathy
24
schizophrenia
24
mental retardation
24
Epstein
24
inflammatory bowel disease
23
mammary tumor
23
renal cancer
23
mental retardation
23
Adenovirus
22
rhabdomyosarcoma
22
neurofibromatosis
22
MIP
22
psoriasis
22
hairy cell leukemia
21
tuberculosis
21
multiple sclerosis
21
myocardial ischemia
21
vaccinia
20
vascular disease
20
erythroleukemia
20
anemia
20
Malignant peripheral nerve sheath tumor
20
cognitive impairment
19
coronary artery disease
19
fatty liver
18
Tumour necrosis
18
Neuroblastoma
18
Neuroblastoma
18
Hippel
18
Kaposi's sarcoma
18
pneumonia
18
pulmonary fibrosis
18
renal failure
17
adenoma
17
epilepsy
17
Glioblastoma
17
hyperinsulinemia
17
Hodgkin's disease
17
cardiomyopathy
17
DDP
17
renal disease
17
FDC
17
FBS
17
NOD
16
meningioma
16
bacterial infection
16
dermatitis
16
metastatic breast cancer
16
diabetic retinopathy
16
aggression
16
hepatitis B
16
Erdheim-Chester disease
15
systemic lupus erythematosus
15
chronic obstructive pulmonary disease
15
dementia
15
stromal tumors
15
T-cell acute lymphoblastic leukemia
15
CEP
15
genetic disorder
15
oral cancer
15
FAS
14
developmental delay
14
MTS
14
medullary thyroid carcinoma
14
medulloblastoma
14
ARF
14
uterus
14
cytomegalovirus
14
myelodysplastic syndrome
14
proteinuria
14
Huntington's disease
14
cirrhosis
14
liver fibrosis
14
malaria
14
juvenile myelomonocytic leukemia
14
basal cell carcinoma
14
liver metastases
13
heart disease
13
chronic pain
13
Burkitt's lymphoma
13
dehydration
13
SCH
13
pulmonary hypertension
13
acute leukemia
13
small cell lung cancer
13
hypertrophic cardiomyopathy
13
dysplasia
13
HCC
13
cardiofaciocutaneous syndrome
13
malnutrition
13
Thyroid cancer
12
embryonal carcinoma
12
Pineal
12
hyperkeratosis
12
AIDS
12
NF2
12
retinopathy
12
developmental disabilities
12
peripheral neuropathy
12
monocytic leukemia
12
TAM
12
hyperlipidemia
12
SAR
12
hepatitis
12
Malignant peripheral nerve sheath tumor
11
insulinoma
11
drug addiction
11
schwannoma
11
skin tumor
11
skin disease
11
adenocarcinoma of the lung
11
PDE
11
memory impairment
11
photosensitivity
11
lupus
10
mole
10
atopic dermatitis
10
subarachnoid hemorrhage
10
macular degeneration
10
T-cell lymphoma
10
stomatitis
10
ulcerative colitis
10
rare disease
10
myelofibrosis
10
Ewing's sarcoma
10
gastrointestinal stromal tumor
10
periodontitis
10
autoimmune disease
10
pruritus
10
choriocarcinoma
10
drug withdrawal
10
paronychia
10
renal ischemia
10
JIP
10
Steroids
10
neuroendocrine tumor
10
keratosis
10
major depressive disorder
10
keratoacanthoma
10
Best
10
chronic hepatitis
10
PML
9
mesothelioma
9
embryonal rhabdomyosarcoma
9
type 1 diabetes
9
Nasopharyngeal carcinoma
9
neutropenia
9
Recruitment
9
neuropathy
9
MRS
9
autism
9
glomerulosclerosis
9
RGS
9
pancreatitis
9
glomerulonephritis
9
bipolar disorder
9
metabolic syndrome
9
liver disease
9
Chlamydia
9
Pituitary
9
brain cancer
9
cholestasis
9
gallbladder cancer
8
CEM
8
epididymis
8
SARS
8
PHA
8
epithelial tumor
8
Helicobacter pylori infection
8
infertility
8
bone metastases
8
chronic myelomonocytic leukemia
8
lymphadenopathy
8
lupus
8
muscular atrophy
8
lung metastases
8
gastritis
8
CCL
8
blast crisis
8
Esophageal squamous cell carcinoma
8
glaucoma
8
Merkel cell carcinoma
8
biliary tract cancer
8
suicide
8
more...
Symptom
pain
108
starvation
62
fatigue
30
seizures
29
diarrhea
29
nausea
24
collapse
17
functional recovery
13
analgesia
9
vomiting
9
headache
8
hypothermia
8
weakness
8
hypotonia
7
arthralgia
6
cachexia
6
hyperoxia
6
exhaustion
6
ataxia
5
splenomegaly
5
respiratory distress
5
skin damage
4
dyspnea
4
anesthesia
4
orofacial pain
4
Neuropathic pain
4
abdominal pain
3
acute stress
3
pelvic pain
3
bone pain
3
memory loss
3
Scratch
3
myalgia
3
erythema
3
dry eye
2
rundown
2
fasciculation
2
cancer pain
2
dry skin
2
acute pain
2
hepatomegaly
2
tremor
2
myoclonus
2
despair
2
angina
2
blurred vision
2
brittle nails
2
chills
2
back pain
2
vertigo
1
dysarthria
1
ENT
1
regurgitation
1
emaciation
1
paresis
1
enuresis
1
thinning
1
cerebellar ataxia
1
Beau's lines
1
onychomadesis
1
asthenia
1
decreased appetite
1
bladder pain
1
knee pain
1
dental pain
1
discomfort
1
bradykinesia
1
urinary frequency
1
Sedation
1
insomnia
1
muscle rigidity
1
twitching
1
distraction
1
spasticity
1
Anoxia
1
scaly skin
1
Organ failure
1
HSA
1
nausea and vomiting
1
neuralgia
1
night sweats
1
numbness
1
muscle stiffness
1
constipation
1
syncope
1
leg pain
1
sore throat
1
abnormal gait
1
general problem
1
Drug
MAP
446
Dermatol
141
ROS
133
Sorafenib
88
CSF
79
IL-2
78
lysine
72
ICI
57
IFN-gamma
56
Angiotensin II
51
ETS
34
Gel
32
Taxol
31
NVP
31
Gefitinib
28
Monit
26
Arsenic trioxide
26
Cardiovasc
24
p75
22
caffeine
22
Forskolin
21
Imatinib
20
vitamin E
18
Activin
18
uPA
18
TAK
18
Ouabain
17
Histamine
16
Cetuximab
16
Ipilimumab
16
ascorbate
16
Retinoic acid
15
Indomethacin
14
Asn
14
Dasatinib
14
ETA
14
Nexavar
13
Glucagon
13
EE2
12
Ethanol
12
Herceptin
12
NADH
12
G-CSF
11
Heme
11
Growth hormone
11
Gleevec
11
Growth hormone
11
RAL
10
Glycyrrhiza
10
IFN-beta
9
PTC
9
Adriamycin
9
PDL
9
Simvastatin
8
CTX
8
CCL
8
ABC
8
Everolimus
8
PCP
7
Epigallocatechin
7
Leaf
7
Erlotinib
7
IL-11
7
K-252a
7
Nephron
7
Nitric Oxide
7
Myricetin
7
MRC
6
Troglitazone
6
lactose
6
PTH
6
Bortezomib
6
CoCl2
6
Rosiglitazone
6
CoCl2
6
Etoposide
5
NBT
5
Lovastatin
5
GEO
5
MDS
5
R1881
5
Tipifarnib
4
Bevacizumab
4
ADR
4
Tarceva
4
citric acid
4
Kenyan
4
CED
4
CTC
4
Emodin
4
ADM
4
Oxaliplatin
4
Gelatin
4
DNase I
4
Rituximab
4
ENT
4
Itraconazole
4
Emodin
4
CTC
4
Estrogens
4
Doxycycline
4
ALA
4
G418
4
GHRP
4
Flavopiridol
3
ZnCl2
3
Alanine
3
GNA
3
Vorinostat
3
KGF
3
THF
3
Taxotere
3
RFP
3
Panitumumab
3
DEX
3
2-Methoxyestradiol
3
EPA
3
TTC
3
CAM
3
Verteporfin
3
BH4
3
Albumin
3
AMC
3
Casodex
3
ZnCl2
3
Propofol
3
-deoxyadenosine
3
Portal
3
Theophylline
3
CPT-11
3
Fulvestrant
3
Lonafarnib
3
TEL
3
Docetaxel
3
Kainic acid
3
Ginseng
3
Ciglitazone
3
Rosuvastatin
3
AraC
3
Fraction
2
Vitamin E
2
nitroglycerin
2
Liraglutide
2
Norplant
2
Sodium nitroprusside
2
Urokinase
2
Xaliproden
2
Fluorescein
2
PFA
2
Aliskiren
2
CTX
2
ACT
2
Capsicum
2
DM1
2
TiO2
2
Zoledronic acid
2
Tianeptine
2
Parkin
2
Rolipram
2
Mutagen
2
Bifidobacterium
2
Zoledronic acid
2
Parkin
2
Phosphatidylserine
2
Apomorphine
2
Romidepsin
2
Fluorescein
2
Photofrin
2
Ezetimibe
2
Alliance
2
Adenosine triphosphate
2
ROC
2
Papaverine
2
FAD
2
Biopolymers
2
3-Methyladenine
2
Glutathione
2
Dihydrotestosterone
2
CTX
2
Amiloride
2
Ilomastat
2
Finasteride
2
Fragment
2
Asthma
2
PFT
2
Cilengitide
2
Azacytidine
2
Sulfamide
2
Magnesium sulfate
2
TAT
2
Award
1
Clodronate
1
Raloxifene
1
CTT
1
Dextrose
1
niacin
1
GRF
1
Bimatoprost
1
OTC
1
KAN
1
Sunitinib malate
1
Iloprost
1
Bosentan
1
Batimastat
1
Pravastatin
1
ID2
1
CMZ
1
Tocilizumab
1
Celebrex
1
Bosentan
1
Red ginseng
1
anti-RSV
1
Adenosine deaminase
1
Amiloride
1
Lercanidipine
1
BTC
1
Tykerb
1
IPD
1
Sodium citrate
1
Bosutinib
1
ZnO
1
pyridoxal phosphate
1
Mevastatin
1
Clofarabine
1
Galactose
1
Vandetanib
1
9-THC
1
TES
1
DEL
1
MDM
1
DHT
1
Budesonide
1
Pertuzumab
1
Pemetrexed
1
Indinavir
1
Quazinone
1
Domperidone
1
Latanoprost
1
Ethane
1
Irinotecan
1
Trifluoperazine
1
DMSA
1
Idebenone
1
Antithrombin III
1
Idarubicin
1
Escitalopram
1
Vitamin K
1
VCR
1
NAG
1
Copaxone
1
MgSO4
1
Denosumab
1
R-gene
1
Onconase
1
Areca
1
Vesnarinone
1
Midostaurin
1
Morphine sulfate
1
Lenalidomide
1
DMAP
1
Temodal
1
OTC
1
Ranitidine
1
CTA
1
Fructose
1
Dial
1
Artesunate
1
VCR
1
Ganciclovir
1
Bayer
1
Tocopherol
1
DHT
1
Luteinizing
1
MTC
1
Batimastat
1
Nephron
1
Cantor
1
Doyle
1
Trib
1
Cilostazol
1
FSH-beta
1
Vitamin A
1
FLP
1
FSH-beta
1
Bumetanide
1
Gastro
1
Nimesulide
1
SnF2
1
CEC
1
Bestatin
1
Hyperforin
1
DFP
1
EML
1
PE2
1
2-Butanol
1
PMEA
1
Atenolol
1
Camp
1
Bromelain
1
Rhamnose
1
Silica
1
Triclosan
1
PDGF B-chain
1
FSH-beta
1
Perphenazine
1
Reserpine
1
Butaprost
1
Rutin
1
Scutellaria root
1
Prednisolone
1
Auranofin
1
Ulinastatin
1
NLF
1
Fluticasone propionate
1
Oseltamivir
1
Sodium citrate
1
Fentanyl
1
Enzyme
MEK
18161
mitogen-activated protein kinase
10639
ERK
6869
protein kinase
2472
protein kinase C
1390
phosphatidylinositol 3-kinase
688
focal adhesion kinase
675
MEKK1
574
MAP
435
caspase-3
382
luciferase
370
phosphoinositide 3-kinase
275
calcineurin
229
phospholipase C
208
proteasome
177
PARP
162
cdc2
149
IKK
149
GSK
138
NADPH oxidase
123
NADPH oxidase
107
phospholipase A2
104
AMP-activated protein kinase
101
AMPK
101
ATPase
96
glutathione S-transferase
91
urokinase-type plasminogen activator
90
collagenase
89
catalase
88
NO synthase
88
thrombin
87
caspase-9
85
CaMKII
84
adenylate cyclase
75
protein phosphatase 2A
70
caspase-8
68
superoxide dismutase
66
PDK1
63
alkaline phosphatase
61
MMP
59
AMPK
57
farnesyltransferase
50
farnesyltransferase
49
lactate dehydrogenase
45
RNA polymerase
43
reverse transcriptase
43
tyrosinase
38
phosphodiesterase
38
APC
37
ACS
33
PKG
32
guanylate cyclase
31
tyrosine hydroxylase
30
myosin light chain kinase
29
trypsin
29
phospholipase D
29
MMP-3
29
NOS
28
peroxidase
27
renin
26
P-glycoprotein
25
MPP
22
MIP
22
DNA methyltransferase
20
DCF
20
lipoxygenase
19
GRK5
19
ornithine decarboxylase
17
CLK1
17
polo-like kinase 1
16
inositol 3-kinase
16
matrix metalloproteinase 9
16
alanine aminotransferase
16
CEP
15
matrix metalloproteinase 2
15
CEP
15
choline acetyltransferase
15
xanthine oxidase
15
caspase-7
14
topoisomerase
14
creatine kinase
14
NQO1
14
caspase-7
14
plasmin
13
RNase
13
gamma-glutamylcysteine synthetase
13
RNase
13
TOR
13
caspase-1
13
beta-galactosidase
12
CD10
12
transcriptase
12
lipase
12
lipoprotein lipase
12
topoisomerase
12
complex I
12
GRK2
12
CPT
11
glutathione peroxidase
11
CPT
11
neuraminidase
11
PDE
11
CPT
11
aldose reductase
11
histidine kinase
10
eEF2 kinase
10
PTPase
10
demethylase
10
acetyl-CoA carboxylase
10
acetylcholinesterase
10
interstitial collagenase
9
furin
9
aspartate aminotransferase
9
cathepsin B
9
sphingosine kinase
9
ACE
9
arginase
9
firefly luciferase
9
histone acetyltransferase
9
12-lipoxygenase
8
cathepsin D
8
hormone-sensitive lipase
8
granzyme B
8
heme oxygenase
8
chloramphenicol acetyltransferase
8
GAS
8
PI-PLC
8
thymidine kinase
8
kinesin
8
histidine decarboxylase
8
caspase-2
7
caspase-2
7
endonuclease
7
PCP
7
glyceraldehyde-3-phosphate dehydrogenase
7
tissue plasminogen activator
6
factor C
6
TACE
6
elastase
6
cathepsin K
6
alcohol dehydrogenase
6
transglutaminase
6
MDR
6
Thy1
6
15-hydroxyprostaglandin dehydrogenase
6
neutral sphingomyelinase
6
CYP3A4
6
ribonucleotide reductase
6
ribonucleotide reductase
6
peroxiredoxin
6
apyrase
5
chaperonin
5
isocitrate dehydrogenase
5
ribonuclease
5
caspase-4
5
ribonuclease
5
biliverdin reductase
5
gamma-glutamyl transpeptidase
5
HCS
5
pyruvate kinase
5
phosphatidylinositol-4,5-bisphosphate 3-kinase
5
soluble epoxide hydrolase
5
hexokinase
5
DNA polymerase
5
triphosphatase
5
malate dehydrogenase
5
chitinase
4
prostate-specific antigen
4
ALDH
4
lysozyme
4
STK11
4
pyruvate dehydrogenase
4
hexosaminidase
4
pyruvate dehydrogenase
4
nitrate reductase
4
nitrate reductase
4
nitrate reductase
4
isocitrate dehydrogenase
4
TdT
4
nitrate reductase
4
15-lipoxygenase
4
enolase
4
Omi/HtrA2
4
thymidylate synthase
4
SPC
4
peptidyl-prolyl cis-trans isomerase
4
thyroid peroxidase
4
glutamine synthetase
4
caspase-4
4
pyruvate dehydrogenase
4
TSA
4
LPL
4
tryptase
4
succinate dehydrogenase
4
phosphoenolpyruvate carboxykinase
4
nitrate reductase
4
phosphoenolpyruvate carboxykinase
4
glutathione reductase
4
NSY
4
phosphoenolpyruvate carboxykinase
4
nitrate reductase
4
lysyl oxidase
4
AST
3
histone demethylase
3
MTD
3
glyceraldehyde-3-phosphate dehydrogenase
3
caspase-6
3
hyaluronidase
3
hyaluronidase
3
glyceraldehyde-3-phosphate dehydrogenase
3
sucrase
3
glutaminase
3
cathepsin L
3
ceramidase
3
glyceraldehyde-3-phosphate dehydrogenase
3
aldehyde dehydrogenase
3
p80
3
Alternating
3
acid phosphatase
3
PRE
3
BAL
3
neutrophil elastase
3
caspase-6
3
ceruloplasmin
3
glycerol-3-phosphate dehydrogenase
3
prolidase
3
adenosine kinase
3
ascorbate peroxidase
3
aldehyde dehydrogenase
3
sialidase
3
S-adenosylmethionine decarboxylase
3
cytochrome oxidase
3
glyceraldehyde-3-phosphate dehydrogenase
3
glycerol-3-phosphate dehydrogenase
3
sucrase-isomaltase
3
thymidine phosphorylase
3
monoamine oxidase
3
TAT
2
aldehyde dehydrogenase
2
ACC synthase
2
ADH
2
isochorismate synthase
2
angiotensin-converting enzyme 2
2
tryptophan hydroxylase
2
SPS
2
prenyltransferase
2
TMT
2
asparaginase
2
protein L-isoaspartyl methyltransferase
2
myosin ATPase
2
indoleamine 2,3-dioxygenase
2
ornithine aminotransferase
2
SOR
2
thromboplastin
2
HSD
2
3-hydroxy-3-methylglutaryl-CoA reductase
2
aldehyde dehydrogenase
2
kallikrein
2
tissue kallikrein
2
ECH
2
urease
2
phosphatidylinositol 4-kinase
2
p100
2
meprin
2
5alpha-reductase
2
carbonic anhydrase
2
chymotrypsin
2
3-hydroxy-3-methylglutaryl-CoA lyase
2
glutathione synthetase
2
thermolysin
2
peptidylarginine deiminase
2
glucose-6-phosphatase
2
urease
2
caspase-10
2
HMG-CoA synthase
2
PAH
2
asparagine synthetase
2
phosphoribulokinase
2
CPS
2
CNPase
2
acyl-CoA oxidase
2
GTP cyclohydrolase I
2
adenosine deaminase
2
DNA ligase
2
DNA ligase
2
diacylglycerol kinase
2
succinic dehydrogenase
2
phosphoglycerate dehydrogenase
2
phosphorylase
2
adenosine deaminase
2
dehydroascorbate reductase
2
pepsin
2
5alpha-reductase
2
CAD
2
ADP-ribosyltransferase
2
CAD
2
ricin
2
glutamate dehydrogenase
2
ADP-ribosyltransferase
2
glutamate dehydrogenase
2
caspase-10
2
glutamate dehydrogenase
2
sialyltransferase
2
cathepsin S
2
endothelin-converting enzyme
2
sialyltransferase
2
aldehyde dehydrogenase
2
sialyltransferase
2
CAD
2
thioredoxin reductase
2
papain
2
cruzipain
2
cytochrome P-450scc
2
matrix metalloproteinase 14
2
UDP-glucose dehydrogenase
1
GM3 synthase
1
prenyltransferase
1
prenyltransferase
1
glucuronosyltransferase I
1
estrogen sulfotransferase
1
more...
Compound
MEK
11589
DNA
1440
Dec
1313
tyrosine
1187
calcium
690
oxygen
685
serine
603
threonine
575
acetate
467
cAMP
461
MAP
437
Clin
367
glucose
343
ATP
327
TNF
250
nitric oxide
241
sodium
240
GTP
201
MTT
191
MDA
190
phosphate
173
methionine
169
Insulin
165
NH2
161
cysteine
156
hydrogen
156
alanine
154
glutamate
148
water
147
PMA
137
PMA
136
AMP
136
N-acetylcysteine
118
retinoic acid
117
leucine
114
H2O2
112
THP
109
THP
109
lysine
103
arginine
99
Ang II
95
Wortmannin
84
GSH
83
GSH
83
cGMP
80
PGE
75
boron
74
zinc
73
salt
68
COS
68
Asp
67
Phe
67
iodine
63
Angiotensin II
63
TPA
61
ATF
61
TPA
61
Cardiol
59
potassium
59
BCR
58
ethanol
57
ICI
57
glycerol
56
ADP
55
bromide
54
proline
53
ABL
53
NMDA
52
LY 294002
51
Rapamycin
51
5-HT
49
sulfate
46
ADP
45
ADP
45
nitrogen
44
pyrimidine
43
urea
42
pyrimidine
42
galactose
41
Tyrosine
41
Phosphatidylinositol
40
dUTP
40
PGE2
40
Genistein
38
aldosterone
34
glutamine
34
Thrombin
34
copper
34
ACS
33
ACS
33
iron
33
NAD
33
ASA
32
GF 109203X
32
SDS
32
GDP
32
Gly
31
glutamic acid
31
DDP
31
Neuronal
31
AMPA
31
vitamin D
31
His
30
UTP
30
Curcumin
29
Resveratrol
28
salicylic acid
28
ADP-ribose
28
cadmium
28
DMSO
26
Estrogen
25
Panam
25
Phorbol
25
PEG
24
pyrrolidine
24
Estrogen
24
NAD
24
PLA
24
Vimentin
23
GAP
23
phosphoserine
23
GABA
22
noradrenaline
22
prostacyclin
22
MPP
22
nicotinamide
22
Serine
22
caffeine
22
FK506
22
MPP
22
uridine
21
CAT
21
Thyroid
21
4-chlorophenyl
21
Adriamycin
21
Forskolin
21
pyrrolidine
21
CAT
21
CAT
21
4-chlorophenyl
21
Phorbol 12-myristate 13-acetate
21
GABA
20
kaempferol
20
acetone
20
Cycloheximide
20
Melatonin
20
SCC
19
Glutamate
19
Cbl
19
MIA
18
creatinine
18
Pac
18
1H-imidazole
18
1H-imidazole
17
acetic acid
17
PGJ2
17
aspartic acid
17
Estradiol
17
Ouabain
17
NADPH
17
NADPH
17
aspartic acid
17
Dexamethasone
16
Tamoxifen
16
Histamine
16
Nicotine
16
Bradykinin
16
Adenosine
16
diacetate
16
ADR
16
Cereb
16
aspartic acid
16
valine
16
aspartic acid
16
Tamoxifen
16
5-FU
15
2-butanone
15
PEG
15
GMP
15
2-butanone
15
HCO
15
tryptophan
15
2-butanone
15
Glycogen synthase
15
benzamide
15
ETA
14
MTS
14
Histone
14
Dopamine
14
Cer
14
DPG
13
Staurosporine
13
pyrene
13
Glucagon
13
Off
13
Carbachol
13
Valproic acid
13
adenosylmethionine
13
manganese
13
Staurosporine
13
Collagen
13
CO2
13
HOG
13
MPTP
13
Retinal
13
TSH
13
naphthoquinone
12
naphthoquinone
12
Quercetin
12
naphthoquinone
12
NADH
12
H2S
12
Isoproterenol
12
Tanshinone
12
naphthoquinone
12
naphthoquinone
12
PAR
12
CPT
12
Progesterone
12
naphthoquinone
12
cobalt
12
MAK
12
aldehyde
12
ACTH
12
Metformin
12
ethyl acetate
12
VP-16
12
Paclitaxel
12
Metformin
12
naphthoquinone
12
HCl
12
ALP
12
prostaglandin F2alpha
12
Arsenite
11
TPCK
11
prostaglandin J2
11
UDP
11
Cholesterol
11
Sphingosine
11
Prostaglandin
11
Heme
11
palmitic acid
11
myricetin
11
methanol
11
Okadaic acid
11
Mg2+
11
toluene
11
Luteolin
11
Ile
11
Prostaglandin
11
CPT
11
hydroxide
10
gamma-aminobutyric acid
10
TNM
10
Cyclosporine
10
Rottlerin
10
pyridine
10
Guo
10
homocysteine
10
nickel
10
Silymarin
10
COX
10
DHA
10
DETA
10
DPI
10
Hoechst 33342
10
hexane
9
Rottlerin
9
Sphingosine 1-phosphate
9
tryptophan
9
fluorine
9
tryptophan
9
DBA
9
BzATP
9
PCP
9
quinoline
9
quinoline
9
ammonium
9
SET
9
Neurotensin
9
Thapsigargin
9
Rottlerin
9
Baicalein
9
GM1
9
NOXA
9
tryptophan
9
Anisomycin
9
Arachidonic acid
9
ABA
9
TEM
8
2-mercaptoethanol
8
APAP
8
GlcNAc
8
LIN
8
DIC
8
Gemcitabine
8
isoquinoline
8
TOF
8
ACh
8
vanadium
8
Polyamine
8
AICAR
8
Oil Red O
8
Gemcitabine
8
aldehyde
8
Actinomycin D
8
silicon
8
quinazoline
8
25-dihydroxycholecalciferol
8
anthracene
8
Lead
8
HMG-CoA
8
quinazoline
8
Celecoxib
8
Phenylephrine
8
hyaluronic acid
8
CTX
8
Chelerythrine
7
Chelerythrine
7
Valproic acid
7
more...