Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.12.2 (MEK)
18,161 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MEK 12715
ERK 6082
MEK1 4168
MAPK 3532
ERK1 3500
p38 2355
Mol 2007
BRAF 1876
extracellular signal-regulated kinase 1837
PI3K 1658
MAP kinase 1470
JNK 1385
mitogen-activated protein 1274
Sep 1250
AKT 1116
RAF 969
mTOR 880
Raf-1 860
c-Jun 840
ERK2 797
tyrosine kinase 779
MKK4 692
cytokine 689
phosphatidylinositol 3-kinase 687
PKC 549
insulin 537
epidermal growth factor 528
KRAS 514
caspase-3 504
EGFR 503
p53 502
epidermal growth factor receptor 492
p42 482
MKK6 442
Bcl-2 436
MAP 435
AP-1 435
p44 426
MEK2 419
phosphatase 417
MEKK 382
threonine 379
MKK7 375
EGF 360
p21 355
ATP 325
MKK3 324
extracellular signal-regulated kinase 1 324
JNK1 323
tumor necrosis factor 316
cyclin D1 293
p38 mitogen-activated protein kinase 285
phosphoinositide 3-kinase 275
STAT3 272
collagen 271
NRAS 271
p38 MAP kinase 269
IL-6 267
PI3 251
TNF 250
ras 247
PKA 245
NS5 241
vascular endothelial growth factor 238
EGF receptor 230
c-fos 230
lipopolysaccharide 223
protein kinase B 216
Rho 215
CREB 205
PTEN 202
GTP 201
nerve growth factor 197
receptor tyrosine kinase 196
STAT 181
platelet-derived growth factor 179
matrix metalloproteinase 179
proteasome 176
p65 174
MEKK1 174
VEGF 174
MAP2K1 168
IL-8 167
fibronectin 165
E-cadherin 163
TNF-alpha 162
catenin 162
estrogen receptor 152
calmodulin 151
cyclooxygenase-2 150
PARP 148
MMP-9 148
cytochrome c 145
chemokine 145
HER2 143
LPS 142
angiotensin II 142
p38MAPK 140
Mcl-1 139
PDGF 139
serine/threonine kinase 138
p27 137
ROS 133
COX-2 133
PP2 133
H-ras 132
AMP 132
GSK 131
interleukin-6 129
cyclin 126
GTPase 126
c-Src 125
JAK2 125
JNK2 125
endoplasmic reticulum 123
RhoA 121
Ang II 121
c-Myc 120
focal adhesion kinase 119
brain-derived neurotrophic factor 118
ribosomal S6 kinase 118
TGF-beta 117
caspase-9 116
phosphorylating 116
PKB 116
nitric oxide synthase 114
inducible nitric oxide synthase 113
MMP-2 112
ubiquitin 111
hepatocyte growth factor 111
insulin-like growth factor 109
THP 109
PLC 108
FGF 107
extracellular signal regulated kinase 107
VEGFR2 106
FAK 104
PIK3CA 103
MAPK/ERK kinase 103
histone 102
protein phosphatase 102
CDK4 102
PI3-kinase 101
IFN 100
MET 100
Fas 100
PP1 99
p90 99
interferon 98
PD-1 98
histone deacetylase 96
B-RAF 94
caspase-8 94
TLR4 94
IKK 93
Cytokine 91
insulin receptor 91
cyclooxygenase 90
ATPase 89
ERK5 89
mitogen-activated protein kinase kinase 1 89
thrombin 89
ASK1 89
PD-L1 87
protein kinase C inhibitor 86
Sp1 86
S6K1 86
BOD 83
proto-oncogene 83
adaptor protein 82
G protein-coupled receptor 82
GSH 82
RSK 81
IkappaBalpha 80
small GTPase 79
HRAS 79
IL-2 78
neurotrophin 77
calcineurin 77
protein tyrosine kinase 77
IRS-1 77
vimentin 76
cyclin E 76
STAT5 76
urokinase-type plasminogen activator 76
adenylyl cyclase 76
TAK1 75
KIT 75
CD4 74
endothelin-1 73
IGF-I 72
adenylate cyclase 72
Smad2 72
cyclin-dependent kinase 72
CTLA-4 72
metalloproteinase 71
CA1 70
MKP-1 70
catalase 70
erythroid 69
survivin 69
IGF-1 69
NGF 68
IL-10 68
annexin V 68
MEK5 67
IL-1 67
GSK3 67
axonal 67
STAT1 66
IL-4 66
ALK 66
erbB-2 66
p70 66
p50 65
tumor necrosis factor alpha 65
p85 65
14-3-3 65
4E-BP1 65
CaMKII 65
NF1 64
beta-catenin 64
osteosarcoma 64
lymphoid 63
MMP9 63
signal transducer and activator of transcription 3 62
SHP-2 62
eIF4E 61
ATF 61
alkaline phosphatase 61
TPA 61
p70 S6 kinase 61
myelin basic protein 60
proteasome inhibitor 60
ribosomal protein S6 60
phospholipase 60
neuregulin 60
interacting protein 60
cyclin A 59
gut 59
leptin 59
osteogenic 59
tyrosine phosphatase 59
proliferating cell nuclear antigen 59
N-cadherin 58
PI-3 kinase 58
MMP 58
Smad3 58
BCL2 58
BCR 58
peroxisome proliferator-activated receptor gamma 58
CD44 58
p16 57
AMPK 57
IFN-gamma 57
CD8 57
MMP-1 57
PP2A 57
c-myc 57
protein kinase 2 56
macrophage colony-stimulating factor 56
polypeptide 55
P38 55
Epidermal growth factor 55
IkappaB kinase 55
K-ras 55
NMDA receptor 54
glycoprotein 54
superoxide dismutase 54
FGF2 54
GST 54
CD11b 54
CXCR4 54
CCL2 54
WAF1 53
RET 53
Rho kinase 53
arrestin 53
fused 53
A431 52
ABL 52
PTPN11 52
MCP-1 52
Elk1 51
TCR 50
Met 50
SRC 50
AMP-activated protein kinase 50
type I collagen 50
Nrf2 50
platelet-derived growth factor receptor 49
LC3 49
MYC 49
protein tyrosine phosphatase 49
Tumor necrosis factor 49
cyclin B1 48
AP1 48
peroxisome proliferator-activated receptor 48
BAX 48
UTR 48
IL-3 48
cAMP response element-binding protein 47
interleukin-2 47
JNK3 47
histone H3 47
SEK 47
c-Met 47
CDK2 46
Leukemia inhibitory factor 46
PD1 46
XIAP 46
HEK 46
MLK3 46
mitogen-activated protein kinase kinase kinase 46
lactate dehydrogenase 45
cAMP-dependent protein kinase 45
PDK1 45
EBP 45
GM-CSF 45
ADP 45
more...
Disease
cancer 3808
tumor 2660
melanoma 1296
breast cancer 600
tumor growth 563
tumorigenesis 552
carcinoma 419
hepatocellular carcinoma 360
leukemia 356
metastatic melanoma 349
lung cancer 349
colorectal cancer 332
carcinogenesis 318
tumor progression 305
adenocarcinoma 275
metastases 249
pertussis 243
non-small cell lung cancer 226
Melanoma 224
MCF 213
colon cancer 211
prostate cancer 201
ischemia 191
pancreatic cancer 187
neuroblastoma 173
glioma 168
acute myeloid leukemia 158
ovarian cancer 157
squamous cell carcinoma 145
atherosclerosis 142
diabetes 140
Alzheimer's disease 131
gastric cancer 127
hypertension 118
multiple myeloma 116
Blocking 109
glioblastoma 101
Parkinson's disease 99
obesity 97
skin cancer 96
lymphoma 88
retinoblastoma 87
pheochromocytoma 84
lung carcinoma 83
chronic myeloid leukemia 83
sarcoma 83
GSH 82
Leukemia 80
thyroid cancer 79
anthrax 79
cerebral ischemia 73
ATM 73
liver cancer 73
osteosarcoma 70
stroke 65
heart failure 65
rheumatoid arthritis 63
depression 61
liver cancer 60
epithelial ovarian cancer 60
asthma 59
HIV 59
virus infection 59
infectious diseases 55
cutaneous melanoma 55
acute lymphoblastic leukemia 55
tumor angiogenesis 54
primary tumor 52
renal cell carcinoma 52
ABL 52
astrocytoma 48
neoplastic transformation 47
acute promyelocytic leukemia 46
Infection 46
aggressiveness 45
neurofibromatosis type 1 44
fibrosarcoma 44
B-cell lymphoma 42
Hepatocellular carcinoma 42
AGS 42
cold 42
type 2 diabetes 42
HGF 41
osteoporosis 40
papillary thyroid cancer 40
influenza 40
osteoarthritis 40
NAME 39
EMT 38
cervical cancer 38
hyperglycemia 38
APC 38
plaque 38
bladder cancer 37
Langerhans cell histiocytosis 36
immunodeficiency 36
addiction 34
glioblastoma multiforme 34
mole 33
brain tumor 33
rash 33
cardiovascular disease 33
sepsis 33
SCID 33
brain metastases 33
colitis 32
myocardial infarction 32
SDS 32
sepsis 32
tumor initiation 30
chronic lymphocytic leukemia 30
hepatitis C 30
hematologic malignancies 29
herpes simplex 29
solid tumor 28
myeloid leukemia 28
Costello syndrome 28
arthritis 28
myeloproliferative disorders 27
chronic lymphocytic leukemia 27
anaplastic thyroid cancer 27
leukemogenesis 27
uveal melanoma 27
Mycobacterium 26
polycystic kidney 26
endometrial cancer 26
chondrosarcoma 26
esophageal cancer 26
stage IV melanoma 25
Adhesion 25
Osteosarcoma 25
cholera 25
Osteosarcoma 25
tuberous sclerosis 24
amyotrophic lateral sclerosis 24
esophageal cancer 24
diabetic nephropathy 24
schizophrenia 24
mental retardation 24
Epstein 24
inflammatory bowel disease 23
mammary tumor 23
renal cancer 23
mental retardation 23
Adenovirus 22
rhabdomyosarcoma 22
neurofibromatosis 22
MIP 22
psoriasis 22
hairy cell leukemia 21
tuberculosis 21
multiple sclerosis 21
myocardial ischemia 21
vaccinia 20
vascular disease 20
erythroleukemia 20
anemia 20
Malignant peripheral nerve sheath tumor 20
cognitive impairment 19
coronary artery disease 19
fatty liver 18
Tumour necrosis 18
Neuroblastoma 18
Neuroblastoma 18
Hippel 18
Kaposi's sarcoma 18
pneumonia 18
pulmonary fibrosis 18
renal failure 17
adenoma 17
epilepsy 17
Glioblastoma 17
hyperinsulinemia 17
Hodgkin's disease 17
cardiomyopathy 17
DDP 17
renal disease 17
FDC 17
FBS 17
NOD 16
meningioma 16
bacterial infection 16
dermatitis 16
metastatic breast cancer 16
diabetic retinopathy 16
aggression 16
hepatitis B 16
Erdheim-Chester disease 15
systemic lupus erythematosus 15
chronic obstructive pulmonary disease 15
dementia 15
stromal tumors 15
T-cell acute lymphoblastic leukemia 15
CEP 15
genetic disorder 15
oral cancer 15
FAS 14
developmental delay 14
MTS 14
medullary thyroid carcinoma 14
medulloblastoma 14
ARF 14
uterus 14
cytomegalovirus 14
myelodysplastic syndrome 14
proteinuria 14
Huntington's disease 14
cirrhosis 14
liver fibrosis 14
malaria 14
juvenile myelomonocytic leukemia 14
basal cell carcinoma 14
liver metastases 13
heart disease 13
chronic pain 13
Burkitt's lymphoma 13
dehydration 13
SCH 13
pulmonary hypertension 13
acute leukemia 13
small cell lung cancer 13
hypertrophic cardiomyopathy 13
dysplasia 13
HCC 13
cardiofaciocutaneous syndrome 13
malnutrition 13
Thyroid cancer 12
embryonal carcinoma 12
Pineal 12
hyperkeratosis 12
AIDS 12
NF2 12
retinopathy 12
developmental disabilities 12
peripheral neuropathy 12
monocytic leukemia 12
TAM 12
hyperlipidemia 12
SAR 12
hepatitis 12
Malignant peripheral nerve sheath tumor 11
insulinoma 11
drug addiction 11
schwannoma 11
skin tumor 11
skin disease 11
adenocarcinoma of the lung 11
PDE 11
memory impairment 11
photosensitivity 11
lupus 10
mole 10
atopic dermatitis 10
subarachnoid hemorrhage 10
macular degeneration 10
T-cell lymphoma 10
stomatitis 10
ulcerative colitis 10
rare disease 10
myelofibrosis 10
Ewing's sarcoma 10
gastrointestinal stromal tumor 10
periodontitis 10
autoimmune disease 10
pruritus 10
choriocarcinoma 10
drug withdrawal 10
paronychia 10
renal ischemia 10
JIP 10
Steroids 10
neuroendocrine tumor 10
keratosis 10
major depressive disorder 10
keratoacanthoma 10
Best 10
chronic hepatitis 10
PML 9
mesothelioma 9
embryonal rhabdomyosarcoma 9
type 1 diabetes 9
Nasopharyngeal carcinoma 9
neutropenia 9
Recruitment 9
neuropathy 9
MRS 9
autism 9
glomerulosclerosis 9
RGS 9
pancreatitis 9
glomerulonephritis 9
bipolar disorder 9
metabolic syndrome 9
liver disease 9
Chlamydia 9
Pituitary 9
brain cancer 9
cholestasis 9
gallbladder cancer 8
CEM 8
epididymis 8
SARS 8
PHA 8
epithelial tumor 8
Helicobacter pylori infection 8
infertility 8
bone metastases 8
chronic myelomonocytic leukemia 8
lymphadenopathy 8
lupus 8
muscular atrophy 8
lung metastases 8
gastritis 8
CCL 8
blast crisis 8
Esophageal squamous cell carcinoma 8
glaucoma 8
Merkel cell carcinoma 8
biliary tract cancer 8
suicide 8
more...
Symptom
pain 108
starvation 62
fatigue 30
seizures 29
diarrhea 29
nausea 24
collapse 17
functional recovery 13
analgesia 9
vomiting 9
headache 8
hypothermia 8
weakness 8
hypotonia 7
arthralgia 6
cachexia 6
hyperoxia 6
exhaustion 6
ataxia 5
splenomegaly 5
respiratory distress 5
skin damage 4
dyspnea 4
anesthesia 4
orofacial pain 4
Neuropathic pain 4
abdominal pain 3
acute stress 3
pelvic pain 3
bone pain 3
memory loss 3
Scratch 3
myalgia 3
erythema 3
dry eye 2
rundown 2
fasciculation 2
cancer pain 2
dry skin 2
acute pain 2
hepatomegaly 2
tremor 2
myoclonus 2
despair 2
angina 2
blurred vision 2
brittle nails 2
chills 2
back pain 2
vertigo 1
dysarthria 1
ENT 1
regurgitation 1
emaciation 1
paresis 1
enuresis 1
thinning 1
cerebellar ataxia 1
Beau's lines 1
onychomadesis 1
asthenia 1
decreased appetite 1
bladder pain 1
knee pain 1
dental pain 1
discomfort 1
bradykinesia 1
urinary frequency 1
Sedation 1
insomnia 1
muscle rigidity 1
twitching 1
distraction 1
spasticity 1
Anoxia 1
scaly skin 1
Organ failure 1
HSA 1
nausea and vomiting 1
neuralgia 1
night sweats 1
numbness 1
muscle stiffness 1
constipation 1
syncope 1
leg pain 1
sore throat 1
abnormal gait 1
general problem 1
Drug
MAP 446
Dermatol 141
ROS 133
Sorafenib 88
CSF 79
IL-2 78
lysine 72
ICI 57
IFN-gamma 56
Angiotensin II 51
ETS 34
Gel 32
Taxol 31
NVP 31
Gefitinib 28
Monit 26
Arsenic trioxide 26
Cardiovasc 24
p75 22
caffeine 22
Forskolin 21
Imatinib 20
vitamin E 18
Activin 18
uPA 18
TAK 18
Ouabain 17
Histamine 16
Cetuximab 16
Ipilimumab 16
ascorbate 16
Retinoic acid 15
Indomethacin 14
Asn 14
Dasatinib 14
ETA 14
Nexavar 13
Glucagon 13
EE2 12
Ethanol 12
Herceptin 12
NADH 12
G-CSF 11
Heme 11
Growth hormone 11
Gleevec 11
Growth hormone 11
RAL 10
Glycyrrhiza 10
IFN-beta 9
PTC 9
Adriamycin 9
PDL 9
Simvastatin 8
CTX 8
CCL 8
ABC 8
Everolimus 8
PCP 7
Epigallocatechin 7
Leaf 7
Erlotinib 7
IL-11 7
K-252a 7
Nephron 7
Nitric Oxide 7
Myricetin 7
MRC 6
Troglitazone 6
lactose 6
PTH 6
Bortezomib 6
CoCl2 6
Rosiglitazone 6
CoCl2 6
Etoposide 5
NBT 5
Lovastatin 5
GEO 5
MDS 5
R1881 5
Tipifarnib 4
Bevacizumab 4
ADR 4
Tarceva 4
citric acid 4
Kenyan 4
CED 4
CTC 4
Emodin 4
ADM 4
Oxaliplatin 4
Gelatin 4
DNase I 4
Rituximab 4
ENT 4
Itraconazole 4
Emodin 4
CTC 4
Estrogens 4
Doxycycline 4
ALA 4
G418 4
GHRP 4
Flavopiridol 3
ZnCl2 3
Alanine 3
GNA 3
Vorinostat 3
KGF 3
THF 3
Taxotere 3
RFP 3
Panitumumab 3
DEX 3
2-Methoxyestradiol 3
EPA 3
TTC 3
CAM 3
Verteporfin 3
BH4 3
Albumin 3
AMC 3
Casodex 3
ZnCl2 3
Propofol 3
-deoxyadenosine 3
Portal 3
Theophylline 3
CPT-11 3
Fulvestrant 3
Lonafarnib 3
TEL 3
Docetaxel 3
Kainic acid 3
Ginseng 3
Ciglitazone 3
Rosuvastatin 3
AraC 3
Fraction 2
Vitamin E 2
nitroglycerin 2
Liraglutide 2
Norplant 2
Sodium nitroprusside 2
Urokinase 2
Xaliproden 2
Fluorescein 2
PFA 2
Aliskiren 2
CTX 2
ACT 2
Capsicum 2
DM1 2
TiO2 2
Zoledronic acid 2
Tianeptine 2
Parkin 2
Rolipram 2
Mutagen 2
Bifidobacterium 2
Zoledronic acid 2
Parkin 2
Phosphatidylserine 2
Apomorphine 2
Romidepsin 2
Fluorescein 2
Photofrin 2
Ezetimibe 2
Alliance 2
Adenosine triphosphate 2
ROC 2
Papaverine 2
FAD 2
Biopolymers 2
3-Methyladenine 2
Glutathione 2
Dihydrotestosterone 2
CTX 2
Amiloride 2
Ilomastat 2
Finasteride 2
Fragment 2
Asthma 2
PFT 2
Cilengitide 2
Azacytidine 2
Sulfamide 2
Magnesium sulfate 2
TAT 2
Award 1
Clodronate 1
Raloxifene 1
CTT 1
Dextrose 1
niacin 1
GRF 1
Bimatoprost 1
OTC 1
KAN 1
Sunitinib malate 1
Iloprost 1
Bosentan 1
Batimastat 1
Pravastatin 1
ID2 1
CMZ 1
Tocilizumab 1
Celebrex 1
Bosentan 1
Red ginseng 1
anti-RSV 1
Adenosine deaminase 1
Amiloride 1
Lercanidipine 1
BTC 1
Tykerb 1
IPD 1
Sodium citrate 1
Bosutinib 1
ZnO 1
pyridoxal phosphate 1
Mevastatin 1
Clofarabine 1
Galactose 1
Vandetanib 1
9-THC 1
TES 1
DEL 1
MDM 1
DHT 1
Budesonide 1
Pertuzumab 1
Pemetrexed 1
Indinavir 1
Quazinone 1
Domperidone 1
Latanoprost 1
Ethane 1
Irinotecan 1
Trifluoperazine 1
DMSA 1
Idebenone 1
Antithrombin III 1
Idarubicin 1
Escitalopram 1
Vitamin K 1
VCR 1
NAG 1
Copaxone 1
MgSO4 1
Denosumab 1
R-gene 1
Onconase 1
Areca 1
Vesnarinone 1
Midostaurin 1
Morphine sulfate 1
Lenalidomide 1
DMAP 1
Temodal 1
OTC 1
Ranitidine 1
CTA 1
Fructose 1
Dial 1
Artesunate 1
VCR 1
Ganciclovir 1
Bayer 1
Tocopherol 1
DHT 1
Luteinizing 1
MTC 1
Batimastat 1
Nephron 1
Cantor 1
Doyle 1
Trib 1
Cilostazol 1
FSH-beta 1
Vitamin A 1
FLP 1
FSH-beta 1
Bumetanide 1
Gastro 1
Nimesulide 1
SnF2 1
CEC 1
Bestatin 1
Hyperforin 1
DFP 1
EML 1
PE2 1
2-Butanol 1
PMEA 1
Atenolol 1
Camp 1
Bromelain 1
Rhamnose 1
Silica 1
Triclosan 1
PDGF B-chain 1
FSH-beta 1
Perphenazine 1
Reserpine 1
Butaprost 1
Rutin 1
Scutellaria root 1
Prednisolone 1
Auranofin 1
Ulinastatin 1
NLF 1
Fluticasone propionate 1
Oseltamivir 1
Sodium citrate 1
Fentanyl 1
Enzyme
MEK 18161
mitogen-activated protein kinase 10639
ERK 6869
protein kinase 2472
protein kinase C 1390
phosphatidylinositol 3-kinase 688
focal adhesion kinase 675
MEKK1 574
MAP 435
caspase-3 382
luciferase 370
phosphoinositide 3-kinase 275
calcineurin 229
phospholipase C 208
proteasome 177
PARP 162
cdc2 149
IKK 149
GSK 138
NADPH oxidase 123
NADPH oxidase 107
phospholipase A2 104
AMP-activated protein kinase 101
AMPK 101
ATPase 96
glutathione S-transferase 91
urokinase-type plasminogen activator 90
collagenase 89
catalase 88
NO synthase 88
thrombin 87
caspase-9 85
CaMKII 84
adenylate cyclase 75
protein phosphatase 2A 70
caspase-8 68
superoxide dismutase 66
PDK1 63
alkaline phosphatase 61
MMP 59
AMPK 57
farnesyltransferase 50
farnesyltransferase 49
lactate dehydrogenase 45
RNA polymerase 43
reverse transcriptase 43
tyrosinase 38
phosphodiesterase 38
APC 37
ACS 33
PKG 32
guanylate cyclase 31
tyrosine hydroxylase 30
myosin light chain kinase 29
trypsin 29
phospholipase D 29
MMP-3 29
NOS 28
peroxidase 27
renin 26
P-glycoprotein 25
MPP 22
MIP 22
DNA methyltransferase 20
DCF 20
lipoxygenase 19
GRK5 19
ornithine decarboxylase 17
CLK1 17
polo-like kinase 1 16
inositol 3-kinase 16
matrix metalloproteinase 9 16
alanine aminotransferase 16
CEP 15
matrix metalloproteinase 2 15
CEP 15
choline acetyltransferase 15
xanthine oxidase 15
caspase-7 14
topoisomerase 14
creatine kinase 14
NQO1 14
caspase-7 14
plasmin 13
RNase 13
gamma-glutamylcysteine synthetase 13
RNase 13
TOR 13
caspase-1 13
beta-galactosidase 12
CD10 12
transcriptase 12
lipase 12
lipoprotein lipase 12
topoisomerase 12
complex I 12
GRK2 12
CPT 11
glutathione peroxidase 11
CPT 11
neuraminidase 11
PDE 11
CPT 11
aldose reductase 11
histidine kinase 10
eEF2 kinase 10
PTPase 10
demethylase 10
acetyl-CoA carboxylase 10
acetylcholinesterase 10
interstitial collagenase 9
furin 9
aspartate aminotransferase 9
cathepsin B 9
sphingosine kinase 9
ACE 9
arginase 9
firefly luciferase 9
histone acetyltransferase 9
12-lipoxygenase 8
cathepsin D 8
hormone-sensitive lipase 8
granzyme B 8
heme oxygenase 8
chloramphenicol acetyltransferase 8
GAS 8
PI-PLC 8
thymidine kinase 8
kinesin 8
histidine decarboxylase 8
caspase-2 7
caspase-2 7
endonuclease 7
PCP 7
glyceraldehyde-3-phosphate dehydrogenase 7
tissue plasminogen activator 6
factor C 6
TACE 6
elastase 6
cathepsin K 6
alcohol dehydrogenase 6
transglutaminase 6
MDR 6
Thy1 6
15-hydroxyprostaglandin dehydrogenase 6
neutral sphingomyelinase 6
CYP3A4 6
ribonucleotide reductase 6
ribonucleotide reductase 6
peroxiredoxin 6
apyrase 5
chaperonin 5
isocitrate dehydrogenase 5
ribonuclease 5
caspase-4 5
ribonuclease 5
biliverdin reductase 5
gamma-glutamyl transpeptidase 5
HCS 5
pyruvate kinase 5
phosphatidylinositol-4,5-bisphosphate 3-kinase 5
soluble epoxide hydrolase 5
hexokinase 5
DNA polymerase 5
triphosphatase 5
malate dehydrogenase 5
chitinase 4
prostate-specific antigen 4
ALDH 4
lysozyme 4
STK11 4
pyruvate dehydrogenase 4
hexosaminidase 4
pyruvate dehydrogenase 4
nitrate reductase 4
nitrate reductase 4
nitrate reductase 4
isocitrate dehydrogenase 4
TdT 4
nitrate reductase 4
15-lipoxygenase 4
enolase 4
Omi/HtrA2 4
thymidylate synthase 4
SPC 4
peptidyl-prolyl cis-trans isomerase 4
thyroid peroxidase 4
glutamine synthetase 4
caspase-4 4
pyruvate dehydrogenase 4
TSA 4
LPL 4
tryptase 4
succinate dehydrogenase 4
phosphoenolpyruvate carboxykinase 4
nitrate reductase 4
phosphoenolpyruvate carboxykinase 4
glutathione reductase 4
NSY 4
phosphoenolpyruvate carboxykinase 4
nitrate reductase 4
lysyl oxidase 4
AST 3
histone demethylase 3
MTD 3
glyceraldehyde-3-phosphate dehydrogenase 3
caspase-6 3
hyaluronidase 3
hyaluronidase 3
glyceraldehyde-3-phosphate dehydrogenase 3
sucrase 3
glutaminase 3
cathepsin L 3
ceramidase 3
glyceraldehyde-3-phosphate dehydrogenase 3
aldehyde dehydrogenase 3
p80 3
Alternating 3
acid phosphatase 3
PRE 3
BAL 3
neutrophil elastase 3
caspase-6 3
ceruloplasmin 3
glycerol-3-phosphate dehydrogenase 3
prolidase 3
adenosine kinase 3
ascorbate peroxidase 3
aldehyde dehydrogenase 3
sialidase 3
S-adenosylmethionine decarboxylase 3
cytochrome oxidase 3
glyceraldehyde-3-phosphate dehydrogenase 3
glycerol-3-phosphate dehydrogenase 3
sucrase-isomaltase 3
thymidine phosphorylase 3
monoamine oxidase 3
TAT 2
aldehyde dehydrogenase 2
ACC synthase 2
ADH 2
isochorismate synthase 2
angiotensin-converting enzyme 2 2
tryptophan hydroxylase 2
SPS 2
prenyltransferase 2
TMT 2
asparaginase 2
protein L-isoaspartyl methyltransferase 2
myosin ATPase 2
indoleamine 2,3-dioxygenase 2
ornithine aminotransferase 2
SOR 2
thromboplastin 2
HSD 2
3-hydroxy-3-methylglutaryl-CoA reductase 2
aldehyde dehydrogenase 2
kallikrein 2
tissue kallikrein 2
ECH 2
urease 2
phosphatidylinositol 4-kinase 2
p100 2
meprin 2
5alpha-reductase 2
carbonic anhydrase 2
chymotrypsin 2
3-hydroxy-3-methylglutaryl-CoA lyase 2
glutathione synthetase 2
thermolysin 2
peptidylarginine deiminase 2
glucose-6-phosphatase 2
urease 2
caspase-10 2
HMG-CoA synthase 2
PAH 2
asparagine synthetase 2
phosphoribulokinase 2
CPS 2
CNPase 2
acyl-CoA oxidase 2
GTP cyclohydrolase I 2
adenosine deaminase 2
DNA ligase 2
DNA ligase 2
diacylglycerol kinase 2
succinic dehydrogenase 2
phosphoglycerate dehydrogenase 2
phosphorylase 2
adenosine deaminase 2
dehydroascorbate reductase 2
pepsin 2
5alpha-reductase 2
CAD 2
ADP-ribosyltransferase 2
CAD 2
ricin 2
glutamate dehydrogenase 2
ADP-ribosyltransferase 2
glutamate dehydrogenase 2
caspase-10 2
glutamate dehydrogenase 2
sialyltransferase 2
cathepsin S 2
endothelin-converting enzyme 2
sialyltransferase 2
aldehyde dehydrogenase 2
sialyltransferase 2
CAD 2
thioredoxin reductase 2
papain 2
cruzipain 2
cytochrome P-450scc 2
matrix metalloproteinase 14 2
UDP-glucose dehydrogenase 1
GM3 synthase 1
prenyltransferase 1
prenyltransferase 1
glucuronosyltransferase I 1
estrogen sulfotransferase 1
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Compound
MEK 11589
DNA 1440
Dec 1313
tyrosine 1187
calcium 690
oxygen 685
serine 603
threonine 575
acetate 467
cAMP 461
MAP 437
Clin 367
glucose 343
ATP 327
TNF 250
nitric oxide 241
sodium 240
GTP 201
MTT 191
MDA 190
phosphate 173
methionine 169
Insulin 165
NH2 161
cysteine 156
hydrogen 156
alanine 154
glutamate 148
water 147
PMA 137
PMA 136
AMP 136
N-acetylcysteine 118
retinoic acid 117
leucine 114
H2O2 112
THP 109
THP 109
lysine 103
arginine 99
Ang II 95
Wortmannin 84
GSH 83
GSH 83
cGMP 80
PGE 75
boron 74
zinc 73
salt 68
COS 68
Asp 67
Phe 67
iodine 63
Angiotensin II 63
TPA 61
ATF 61
TPA 61
Cardiol 59
potassium 59
BCR 58
ethanol 57
ICI 57
glycerol 56
ADP 55
bromide 54
proline 53
ABL 53
NMDA 52
LY 294002 51
Rapamycin 51
5-HT 49
sulfate 46
ADP 45
ADP 45
nitrogen 44
pyrimidine 43
urea 42
pyrimidine 42
galactose 41
Tyrosine 41
Phosphatidylinositol 40
dUTP 40
PGE2 40
Genistein 38
aldosterone 34
glutamine 34
Thrombin 34
copper 34
ACS 33
ACS 33
iron 33
NAD 33
ASA 32
GF 109203X 32
SDS 32
GDP 32
Gly 31
glutamic acid 31
DDP 31
Neuronal 31
AMPA 31
vitamin D 31
His 30
UTP 30
Curcumin 29
Resveratrol 28
salicylic acid 28
ADP-ribose 28
cadmium 28
DMSO 26
Estrogen 25
Panam 25
Phorbol 25
PEG 24
pyrrolidine 24
Estrogen 24
NAD 24
PLA 24
Vimentin 23
GAP 23
phosphoserine 23
GABA 22
noradrenaline 22
prostacyclin 22
MPP 22
nicotinamide 22
Serine 22
caffeine 22
FK506 22
MPP 22
uridine 21
CAT 21
Thyroid 21
4-chlorophenyl 21
Adriamycin 21
Forskolin 21
pyrrolidine 21
CAT 21
CAT 21
4-chlorophenyl 21
Phorbol 12-myristate 13-acetate 21
GABA 20
kaempferol 20
acetone 20
Cycloheximide 20
Melatonin 20
SCC 19
Glutamate 19
Cbl 19
MIA 18
creatinine 18
Pac 18
1H-imidazole 18
1H-imidazole 17
acetic acid 17
PGJ2 17
aspartic acid 17
Estradiol 17
Ouabain 17
NADPH 17
NADPH 17
aspartic acid 17
Dexamethasone 16
Tamoxifen 16
Histamine 16
Nicotine 16
Bradykinin 16
Adenosine 16
diacetate 16
ADR 16
Cereb 16
aspartic acid 16
valine 16
aspartic acid 16
Tamoxifen 16
5-FU 15
2-butanone 15
PEG 15
GMP 15
2-butanone 15
HCO 15
tryptophan 15
2-butanone 15
Glycogen synthase 15
benzamide 15
ETA 14
MTS 14
Histone 14
Dopamine 14
Cer 14
DPG 13
Staurosporine 13
pyrene 13
Glucagon 13
Off 13
Carbachol 13
Valproic acid 13
adenosylmethionine 13
manganese 13
Staurosporine 13
Collagen 13
CO2 13
HOG 13
MPTP 13
Retinal 13
TSH 13
naphthoquinone 12
naphthoquinone 12
Quercetin 12
naphthoquinone 12
NADH 12
H2S 12
Isoproterenol 12
Tanshinone 12
naphthoquinone 12
naphthoquinone 12
PAR 12
CPT 12
Progesterone 12
naphthoquinone 12
cobalt 12
MAK 12
aldehyde 12
ACTH 12
Metformin 12
ethyl acetate 12
VP-16 12
Paclitaxel 12
Metformin 12
naphthoquinone 12
HCl 12
ALP 12
prostaglandin F2alpha 12
Arsenite 11
TPCK 11
prostaglandin J2 11
UDP 11
Cholesterol 11
Sphingosine 11
Prostaglandin 11
Heme 11
palmitic acid 11
myricetin 11
methanol 11
Okadaic acid 11
Mg2+ 11
toluene 11
Luteolin 11
Ile 11
Prostaglandin 11
CPT 11
hydroxide 10
gamma-aminobutyric acid 10
TNM 10
Cyclosporine 10
Rottlerin 10
pyridine 10
Guo 10
homocysteine 10
nickel 10
Silymarin 10
COX 10
DHA 10
DETA 10
DPI 10
Hoechst 33342 10
hexane 9
Rottlerin 9
Sphingosine 1-phosphate 9
tryptophan 9
fluorine 9
tryptophan 9
DBA 9
BzATP 9
PCP 9
quinoline 9
quinoline 9
ammonium 9
SET 9
Neurotensin 9
Thapsigargin 9
Rottlerin 9
Baicalein 9
GM1 9
NOXA 9
tryptophan 9
Anisomycin 9
Arachidonic acid 9
ABA 9
TEM 8
2-mercaptoethanol 8
APAP 8
GlcNAc 8
LIN 8
DIC 8
Gemcitabine 8
isoquinoline 8
TOF 8
ACh 8
vanadium 8
Polyamine 8
AICAR 8
Oil Red O 8
Gemcitabine 8
aldehyde 8
Actinomycin D 8
silicon 8
quinazoline 8
25-dihydroxycholecalciferol 8
anthracene 8
Lead 8
HMG-CoA 8
quinazoline 8
Celecoxib 8
Phenylephrine 8
hyaluronic acid 8
CTX 8
Chelerythrine 7
Chelerythrine 7
Valproic acid 7
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