Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.12.2 (MEK)
18,161 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MEK 0.700
MEK1 0.229
ERK 0.078
ERK1 0.030
MKK4 0.029
RAF 0.027
MEK2 0.023
MKK6 0.023
MAPK 0.022
BRAF 0.020
MKK7 0.019
extracellular signal-regulated kinase 0.015
MAP kinase 0.014
p38 0.010
ERK2 0.010
MKK3 0.009
Raf-1 0.009
mitogen-activated protein 0.008
MEKK 0.008
PI3K 0.006
more...
Disease
melanoma 0.001
metastatic melanoma 0.001
cancer 0.001
tumor 0.001
Melanoma 0.000
tumor growth 0.000
tumorigenesis 0.000
pertussis 0.000
Costello syndrome 0.000
cardiofaciocutaneous syndrome 0.000
tumor progression 0.000
non-small cell lung cancer 0.000
breast cancer 0.000
colorectal cancer 0.000
hepatocellular carcinoma 0.000
RP27 0.000
stage IV melanoma 0.000
pancreatic cancer 0.000
lung cancer 0.000
MCF 0.000
more...
Symptom
starvation 0.000
brittle nails 0.000
Beau's lines 0.000
Organ failure 0.000
pain 0.000
onychomadesis 0.000
Scratch 0.000
nausea 0.000
orofacial pain 0.000
scaly skin 0.000
fatigue 0.000
rundown 0.000
Neuropathic pain 0.000
skin damage 0.000
diarrhea 0.000
functional recovery 0.000
collapse 0.000
seizures 0.000
hypotonia 0.000
bladder pain 0.000
more...
Drug
MAP 0.001
Sorafenib 0.000
Nexavar 0.000
Xaliproden 0.000
NVP 0.000
ROS 0.000
Ipilimumab 0.000
Gefitinib 0.000
Quazinone 0.000
ICI 0.000
Arsenic trioxide 0.000
Angiotensin II 0.000
RAL 0.000
Sulfamide 0.000
ETS 0.000
Lonafarnib 0.000
Dasatinib 0.000
TAK 0.000
Tipifarnib 0.000
Taxol 0.000
more...
Enzyme
MEK 1.000
mitogen-activated protein kinase 0.065
ERK 0.027
MEKK1 0.010
protein kinase 0.004
phosphatidylinositol 3-kinase 0.002
protein kinase C 0.002
MAP 0.001
phosphoinositide 3-kinase 0.001
focal adhesion kinase 0.001
IKK 0.000
caspase-3 0.000
luciferase 0.000
calcineurin 0.000
GSK 0.000
cdc2 0.000
farnesyltransferase 0.000
phospholipase C 0.000
PARP 0.000
PDK1 0.000
more...
Compound
MEK 0.576
MAP 0.001
tyrosine 0.001
LY 294002 0.001
threonine 0.000
Wortmannin 0.000
serine 0.000
cAMP 0.000
GF 109203X 0.000
DNA 0.000
PMA 0.000
ATF 0.000
acetate 0.000
PMA 0.000
MDA 0.000
calcium 0.000
GTP 0.000
Ang II 0.000
Catenarin 0.000
N-acetylcysteine 0.000
more...