Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.12.2 (MEK)
 18,161 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
TCF2 protein 10.8
FAM73A 10.8
MAP3K8 protein 10.8
Signal protein 10.8
MEK1 10.8
SNAP25-interacting protein 10.8
G6f protein 10.8
RIT1 protein 10.8
PLA2G16 protein 10.8
PTPN5 protein 10.8
guanine nucleotide-releasing factor 2 10.8
MEK 10.8
HMGCL protein 10.8
CNN2 protein 10.8
TMEM55A 10.8
topoisomerase III beta 10.8
jumonji C domain containing histone demethylase 1 homolog D 10.8
MRIP-1 10.8
MEK2 10.7
MKK6 10.7
more...
Disease
RP27 10.2
Papillary craniopharyngioma 9.8
Histiocytic neoplasms 8.8
Precursor T-cell lymphoblastic lymphoma 8.8
HPC3 8.8
NRC1 8.8
Opsismodysplasia 8.5
Congenital melanocytic nevus 8.3
cardiofaciocutaneous syndrome 8.1
adult pilocytic astrocytoma 8.0
Mucinous Neoplasm 8.0
Gastrointestinal anthrax 7.8
phakoma 7.6
Conjunctival melanoma 7.5
Malignant Peripheral Nerve Sheath Tumor 7.5
Costello syndrome 7.4
DSCR 7.2
Pilocytic astrocytoma 6.9
Neutrophilic panniculitis 6.9
Gastrointestinal mucositis 6.9
more...
Symptom
brittle nails 5.8
Beau's lines 5.0
Organ failure 4.8
onychomadesis 4.3
Scratch 3.7
scaly skin 3.3
orofacial pain 2.9
rundown 2.8
Neuropathic pain 2.3
skin damage 2.2
bladder pain 2.2
starvation 2.1
dry skin 1.8
Anoxia 1.7
fasciculation 1.4
despair 1.1
hypotonia 1.1
general problem 1.0
hyperoxia 1.0
cachexia 0.9
more...
Drug
Xaliproden 9.2
Quazinone 8.8
Nexavar 7.7
Sulfamide 7.7
2-Butanol 7.3
Lonafarnib 7.2
Sorafenib 6.7
Tipifarnib 6.6
Ilomastat 6.5
Scutellaria root 6.4
RAL 6.1
Ipilimumab 6.1
Ciglitazone 6.1
NVP 5.8
MAP 5.6
Cilengitide 5.6
Gefitinib 5.4
Mevastatin 5.3
Dasatinib 5.3
Myricetin 5.3
more...
Enzyme
MEK 10.8
MEKK1 9.1
mitogen-activated protein kinase 7.6
glucuronosyltransferase I 7.5
CLK1 7.3
ERK 7.0
inositol 3-kinase 6.9
NSY 6.9
prenylated protein methyltransferase 6.8
phosphatidylinositol 3-kinase 6.8
MAP 6.7
small monomeric GTPase 6.6
farnesyltransferase 6.4
phosphoinositide 3-kinase 6.4
eEF2 kinase 6.2
duodenase 6.1
farnesyltransferase 5.9
protein kinase 5.7
IKK 5.7
protein kinase C 5.6
more...
Compound
Catenarin 10.8
MEK 10.6
Cajanin 9.8
N-(2-pyridinyl)benzamide 9.2
4-(4-chlorophenyl)-4-piperidinol 9.2
Xanthoxyletin 9.2
Telocinobufagin 8.8
LY 294002 8.3
DG 2 8.0
3-quinolinecarbonitrile 7.8
1,2,4-trimethylcyclohexane 7.8
Ginkgolide C 7.8
Dracorhodin 7.8
1,2,4-trimethylcyclohexane 7.8
Rocaglamide 7.7
3,4-D 7.7
Cyclovirobuxine D 7.5
2,4,5-trimethoxybenzaldehyde 7.5
Senegenin 7.5
Malabaricone C 7.5
more...