Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.12.2 (
MEK
)
18,161
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Expression analysis of
MKK6
protein in solid tumors has never been investigated. Here, we report systematic analysis of
MKK6
protein in different types of human tumor samples using western blotting and immunofluorescence techniques. We observed significant increase in the expression of
MKK6
in Esophageal,
Stomach
, and Colon cancers as compared to controls. Results were alternately confirmed by Immunofluorescence studies. Upregulation of
MKK6
protein is indicative of its role in human cancers and could possibly be used as a novel diagnostic or prognostic marker in these cancers.
...
PMID:MKK6 is upregulated in human esophageal, stomach, and colon cancers. 2501 14
