Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.11.31 (
AMP-activated protein kinase
)
13,065
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
AMP-activated protein kinase
0.553
AMPK
0.476
AICAR
0.028
LKB1
0.028
acetyl-CoA carboxylase
0.013
mTOR
0.011
PGC
0.006
ULK1
0.006
CaMKK
0.005
SIRT1
0.003
adiponectin
0.003
insulin
0.002
GLUT4
0.002
peroxisome proliferator-activated receptor
0.002
LC3
0.002
Adiponectin
0.002
ACC
0.002
sirtuin 1
0.002
PRKAA1
0.002
fatty acid synthase
0.002
TBC1D1
0.002
AMP
0.001
Beclin-1
0.001
p62
0.001
ATP
0.001
AS160
0.001
glucose transporter 4
0.001
ampk
0.001
sterol regulatory element-binding protein
0.001
AKT
0.001
STRAD
0.001
PI3K
0.001
S6K1
0.001
PRKAA2
0.001
IRS-1
0.001
PRKAA
0.001
SREBP-1c
0.001
NUAK2
0.001
carnitine palmitoyltransferase 1
0.001
PRKAG2
0.001
STO
0.001
LC3B
0.001
TBC1D4
0.001
NUAK1
0.001
CPT1
0.001
carnitine palmitoyltransferase
0.001
SREBP-1
0.001
PPAR
0.001
MO25
0.001
sterol regulatory element-binding protein-1c
0.001
protein kinase B
0.001
leptin
0.001
TSC2
0.001
FNIP1
0.001
adipose triglyceride lipase
0.001
adiponectin receptor 1
0.000
glucose transporter
0.000
PRKAG1
0.000
ARK5
0.000
adipokine
0.000
CAMKK
0.000
BRSK2
0.000
PRKAB2
0.000
peroxisome proliferator-activated receptor gamma
0.000
4E-BP1
0.000
uncoupling protein 1
0.000
TFAM
0.000
MAPK
0.000
p38
0.000
CAMKK2
0.000
PGC1
0.000
CaMKII
0.000
ROS
0.000
FAS
0.000
ACC2
0.000
4EBP1
0.000
serine/threonine kinase 11
0.000
ribosomal protein S6
0.000
PGC-1
0.000
UCP2
0.000
more...
Disease
obesity
0.001
type 2 diabetes
0.001
fatty liver
0.001
diabetes
0.000
hyperglycemia
0.000
metabolic syndrome
0.000
alcoholic fatty liver
0.000
cancer
0.000
FAS
0.000
SAMS
0.000
tumor
0.000
Nonalcoholic fatty liver
0.000
Peutz-Jeghers syndrome
0.000
tuberous sclerosis
0.000
diabetic cardiomyopathy
0.000
dyslipidemia
0.000
hyperlipidemia
0.000
glucose intolerance
0.000
ischemia
0.000
tumor growth
0.000
hepatocellular carcinoma
0.000
Female hypogonadism
0.000
CCAL1
0.000
metabolic disorder
0.000
Amino acid deficiency
0.000
tumorigenesis
0.000
diabetic nephropathy
0.000
atherosclerosis
0.000
SCD
0.000
myocardial ischemia
0.000
breast cancer
0.000
cardiovascular disease
0.000
hyperinsulinemia
0.000
poor fetal development
0.000
tumor progression
0.000
INS
0.000
ATM
0.000
Infantile diarrhea
0.000
Alzheimer's disease
0.000
heart failure
0.000
BHD
0.000
OPA1
0.000
EBSS
0.000
BHD
0.000
lipid disorder
0.000
prostate cancer
0.000
Secretory diarrhea
0.000
colon cancer
0.000
EPM2B
0.000
colorectal cancer
0.000
ATP synthase deficiency
0.000
hypoglycemia
0.000
pancreatic cancer
0.000
GSH
0.000
Wolff-Parkinson-White syndrome
0.000
muscular atrophy
0.000
MCF
0.000
lung cancer
0.000
liver fibrosis
0.000
muscle cancer
0.000
cerebral ischemia
0.000
glioblastoma
0.000
Blocking
0.000
hyperphagia
0.000
liver disease
0.000
Bateman
0.000
neuroblastoma
0.000
cardiomyopathy
0.000
carcinogenesis
0.000
IMD1
0.000
female subfertility
0.000
non-small cell lung cancer
0.000
hypertension
0.000
polycystic ovary syndrome
0.000
overnutrition
0.000
Hypophagia
0.000
Parkinson's disease
0.000
liver cancer
0.000
liver scarring
0.000
NAME
0.000
more...
Symptom
starvation
0.000
cachexia
0.000
exhaustion
0.000
fatigue
0.000
stomach cramps
0.000
functional recovery
0.000
Cold intolerance
0.000
hunger
0.000
overweight
0.000
rundown
0.000
collapse
0.000
memory loss
0.000
anorexia
0.000
aphagia
0.000
Cushingoid
0.000
Cushingoid
0.000
Anoxia
0.000
menopausal symptoms
0.000
hypercapnia
0.000
weakness
0.000
Scratch
0.000
respiratory distress
0.000
hypothermia
0.000
pain
0.000
stomach pain
0.000
POA
0.000
Decreased activity
0.000
hyperoxia
0.000
Neuropathic pain
0.000
neurological disability
0.000
acute pain
0.000
bradykinesia
0.000
Hudson
0.000
muscle rigidity
0.000
splenomegaly
0.000
pallor
0.000
acute stress
0.000
decreased appetite
0.000
diarrhea
0.000
anesthesia
0.000
HSA
0.000
bitter taste
0.000
seizures
0.000
hepatomegaly
0.000
skin damage
0.000
myalgia
0.000
incoordination
0.000
chills
0.000
polydipsia
0.000
angina
0.000
low back pain
0.000
ataxia
0.000
dry eye
0.000
shoulder pain
0.000
thinning
0.000
ophthalmoplegia
0.000
cyanosis
0.000
myoclonus
0.000
tremor
0.000
insomnia
0.000
Ill
0.000
back pain
0.000
hypotonia
0.000
hemoptysis
0.000
spasticity
0.000
acidity
0.000
arthralgia
0.000
spasm
0.000
syncope
0.000
cough
0.000
agitation
0.000
stigma
0.000
abdominal pain
0.000
headache
0.000
discomfort
0.000
nausea
0.000
discomfort
0.000
dyspnea
0.000
analgesia
0.000
vomiting
0.000
more...
Drug
ROS
0.000
Aicar
0.000
Acadesine
0.000
Benproperine phosphate
0.000
Parkin
0.000
Parkin
0.000
Cassia seed
0.000
Adenosine Monophosphate
0.000
3-Methyladenine
0.000
Ara-A
0.000
Liraglutide
0.000
Rosiglitazone
0.000
Fidarestat
0.000
Fidarestat
0.000
RFP
0.000
Emodin
0.000
Glucagon
0.000
NADH
0.000
Emodin
0.000
Safingol
0.000
Ginseng
0.000
Troglitazone
0.000
Metreleptin
0.000
1-Deoxynojirimycin
0.000
Crotonaldehyde
0.000
Sorafenib
0.000
Pramlintide
0.000
Orlistat
0.000
Cilostazol
0.000
Ethanol
0.000
Nelarabine
0.000
Salicylate
0.000
Ciglitazone
0.000
Aescin
0.000
Vitamin K2
0.000
Fructose
0.000
Januvia
0.000
Glucose-6-Phosphate
0.000
metformin hydrochloride
0.000
Mevastatin
0.000
Amlexanox
0.000
Glycyrrhiza
0.000
Epigallocatechin
0.000
Ezetimibe
0.000
Adamantane
0.000
Penfluridol
0.000
Sesamol
0.000
Creosote
0.000
caffeine
0.000
Simvastatin
0.000
CTZ
0.000
AIC
0.000
TAK
0.000
Angiotensin II
0.000
Rosuvastatin calcium
0.000
Esculin
0.000
Virginiamycin
0.000
Jujube
0.000
Omapatrilat
0.000
lysine
0.000
Exenatide
0.000
Rimonabant
0.000
Ramelteon
0.000
Telbivudine
0.000
Lovastatin
0.000
Cangrelor
0.000
Artesunate
0.000
Pravastatin
0.000
Cinacalcet
0.000
AMK
0.000
Kenyan
0.000
Insulin glargine
0.000
Pemetrexed
0.000
Coconut oil
0.000
Clove
0.000
Aricept
0.000
Nexavar
0.000
Ranolazine
0.000
Ranolazine
0.000
CMX
0.000
more...
Enzyme
AMP-activated protein kinase
1.000
AMPK
0.471
AMPK
0.241
acetyl-CoA carboxylase
0.013
protein kinase
0.002
mitogen-activated protein kinase
0.001
AMP-activated kinase
0.001
CPT
0.001
reductase phosphatase
0.000
hormone-sensitive lipase
0.000
STK11
0.000
CaMKII
0.000
malonyl-CoA decarboxylase
0.000
CPT
0.000
eEF2 kinase
0.000
CPT
0.000
phosphoenolpyruvate carboxykinase
0.000
TOR
0.000
glucose-6-phosphatase
0.000
complex I
0.000
phosphatidylinositol 3-kinase
0.000
citrate synthase
0.000
ERK
0.000
caspase-3
0.000
PDK1
0.000
calcineurin
0.000
calpain C
0.000
GSK
0.000
protein phosphatase 2A
0.000
phosphoenolpyruvate carboxykinase
0.000
phosphoenolpyruvate carboxykinase
0.000
focal adhesion kinase
0.000
3-hydroxy-3-methylglutaryl-CoA reductase
0.000
phosphoinositide 3-kinase
0.000
PARP
0.000
superoxide dismutase
0.000
protein kinase C
0.000
aspartate aminotransferase
0.000
alanine aminotransferase
0.000
D-dopachrome tautomerase
0.000
adenosine kinase
0.000
HK2
0.000
glucokinase
0.000
nicotinamide phosphoribosyltransferase
0.000
MEK
0.000
acyl-CoA oxidase
0.000
NO synthase
0.000
IKK
0.000
lipoprotein lipase
0.000
phosphatidylinositol 3-phosphate 5-kinase
0.000
NADPH oxidase
0.000
NADPH oxidase
0.000
proteasome
0.000
AST
0.000
O-GlcNAc transferase
0.000
hexokinase
0.000
heme oxygenase
0.000
3-hydroxy-3-methylglutaryl coenzyme A reductase
0.000
pyruvate kinase
0.000
carnitine O-octanoyltransferase
0.000
pyruvate dehydrogenase
0.000
pyruvate dehydrogenase
0.000
pyruvate dehydrogenase
0.000
catalase
0.000
6-phosphofructo-2-kinase
0.000
lactate dehydrogenase
0.000
phosphofructokinase
0.000
caspase-1
0.000
retinol saturase
0.000
caspase-9
0.000
YeiK
0.000
PKG
0.000
phosphorylase
0.000
ATP synthase
0.000
fatty-acid synthase
0.000
acyl-CoA dehydrogenase
0.000
luciferase
0.000
gamma-glutamylcyclotransferase
0.000
NQO1
0.000
NOS
0.000
more...
Compound
AICAR
0.028
AICAR
0.019
Metformin
0.008
Metformin
0.008
glucose
0.003
AMP
0.002
ATP
0.001
AICA-riboside
0.001
malonyl-CoA
0.001
adenylate
0.000
threonine
0.000
Guo
0.000
Resveratrol
0.000
Aminoimidazole
0.000
oxygen
0.000
Berberine
0.000
CPT
0.000
CoA
0.000
CPT
0.000
Oil Red O
0.000
Oil Red O
0.000
Insulin
0.000
TNF
0.000
palmitic acid
0.000
TSC
0.000
Hispidulin
0.000
Evoxine
0.000
palmitic acid
0.000
NAD
0.000
Hernandezine
0.000
DBI
0.000
serine
0.000
NAD
0.000
Dihydromyricetin
0.000
Rapamycin
0.000
4-Bromodiphenyl ether
0.000
4-Bromodiphenyl ether
0.000
2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
0.000
acetyl-CoA
0.000
Ginkgolide C
0.000
cAMP
0.000
STZ
0.000
ADP
0.000
Saponarin
0.000
ADP
0.000
ADP
0.000
Scirpusin A
0.000
Oxyphenisatin
0.000
Tubeimoside I
0.000
nitric oxide
0.000
3-Methyladenine
0.000
Deuterohemin
0.000
2,5-dichlorobenzenesulfonamide
0.000
Deuterohemin
0.000
HMG-CoA
0.000
Fenofibrate
0.000
Tuberin
0.000
Glycogen
0.000
calcium
0.000
Batatasin I
0.000
9H-xanthene-9-carboxylic acid
0.000
Tephrosin
0.000
Justicidin A
0.000
Sinensetin
0.000
Ginkgolide C
0.000
p-Synephrine
0.000
N-acetylcysteine
0.000
nicotinamide
0.000
Wuweizisu C
0.000
Isoorientin
0.000
Gartanin
0.000
Catalpol
0.000
pentose
0.000
pentose
0.000
MDA
0.000
Wedelolactone
0.000
pentose
0.000
Prunetin
0.000
Jervine
0.000
methyl dihydrogen phosphate
0.000
more...