Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.31 (AMP-activated protein kinase)
 13,065 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
KIAA0173 11.3
phosphoinositide-3-kinase adaptor protein 1 11.3
proline rich 5 11.3
PRO1853 11.3
mitochondrial translation optimization 1 homolog 11.3
GRIK2 protein 11.3
phosphodiesterase 3B, cGMP-inhibited 11.3
AMPK beta 1 11.3
LONP 11.3
peroxisomal biogenesis factor 3 11.3
AMPK 11.3
C12orf73 11.3
CEBPD protein 11.3
WD repeat domain 24 11.3
DNM1L protein 11.3
AMP-activated protein kinase 11.2
AICAR 10.7
CAMKK 10.7
LC27 10.7
protein kinase, AMP-activated, gamma 2 non-catalytic subunit 10.7
ampk 10.6
PRKAG1 10.5
CaMKK 10.5
PRKAA 10.4
LKB1 10.3
NUAK2 10.3
WD repeat and FYVE domain containing 3 10.3
NSPL1 10.3
Rab40A 10.3
mitogen-activated protein kinase associated protein 1 10.3
BR serine/threonine kinase 1 10.3
ubiquitin specific peptidase 10 10.3
plakophilin 4 10.3
6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase 10.3
TBC1D7 protein 10.3
SSTK 10.3
TBC1D1 protein 10.3
TBC1 domain family member 1 10.3
PRKAA2 10.3
GLB1L 10.3
WD repeat-containing protein 35 10.3
BRSK2 10.2
PRKAB2 10.2
FNIP1 10.0
PRKAA1 10.0
TBC1D1 10.0
STRAD 9.9
calcium binding protein 39 9.9
WD repeat domain, phosphoinositide interacting 1 9.9
AMPK1 9.9
ARK5 9.9
CAB39 9.9
NUAK1 9.9
MO25 9.8
BRSK1 9.8
FNIP2 9.8
chorionic somatomammotropin hormone 1 9.7
transmembrane protein 26 9.7
neighbor of BRCA1 gene 2 9.7
ITGB4 protein 9.7
SET and MYND domain containing 1 9.7
Meteorin-like protein 9.7
RAB2A, member RAS oncogene family 9.7
TBC1 domain family member 7 9.7
Wilms tumor 1-associating protein 9.7
ATP6V0E2 9.7
ALCAT1 9.7
immune associated nucleotide 9.7
mitogen-activated protein kinase kinase kinase 9 9.7
Polycystic kidney disease 2-like 1 9.7
DEFB109 9.7
DEFB125 9.7
Erbb2 interacting protein 9.7
LTBP1 protein 9.7
makorin ring finger protein 1 9.7
AP2 associated kinase 1 9.7
nNOSmu 9.7
CAMKK2 9.7
ARMCX3 9.7
TBC1D4 9.6
more...
Disease
Female hypogonadism 10.3
CCAL1 9.7
Amino acid deficiency 9.3
SAMS 8.8
poor fetal development 8.3
Infantile diarrhea 8.1
ATP synthase deficiency 7.6
Secretory diarrhea 7.5
EBSS 7.3
muscle cancer 7.3
EPM2B 7.1
IMD1 7.1
BHD 7.0
Hypophagia 6.9
BHD 6.9
liver scarring 6.9
female subfertility 6.8
Multiple cancer 6.8
Diabetic encephalopathy 6.6
Peutz-Jeghers syndrome 6.6
fatty liver 6.2
alcoholic fatty liver 6.2
diabetic cardiomyopathy 6.2
FAS 6.1
AML progression 6.0
WTS 5.9
Hypoxic-ischemic encephalopathy (HIE) 5.9
Bateman 5.8
MODY1 5.8
Fulminant hepatitis 5.8
NEK1 5.8
Sepsis-associated encephalopathy 5.7
SCD 5.7
adult brain tumor 5.7
Nonalcoholic fatty liver 5.7
Simpson-Golabi-Behmel syndrome 5.7
OPA1 5.7
Congenital nephrogenic diabetes insipidus 5.6
Hers 5.6
Cancer cachexia 5.6
lipid disorder 5.5
Conduction disorders 5.4
Diabetic peripheral neuropathy 5.4
Leukemia stem cell 5.4
adaptation reaction 5.4
TGCT 5.4
recurrent thyroid cancer 5.3
tuberous sclerosis 5.3
type 2 diabetes 5.3
Biotin deficiency 5.3
Hypoxic-ischemic brain injury 5.3
TD2 5.3
INS 5.2
JHS 5.2
Renal interstitial fibrosis 5.1
Epididymis 5.0
Epididymis 5.0
CSE 5.0
disorders of amino acid metabolism 5.0
metabolic syndrome 4.9
overnutrition 4.9
hyperglycemia 4.9
Peritoneal fibrosis 4.9
Diastolic heart failure 4.9
Mycobacterium marinum infection 4.9
obesity 4.8
Autosomal dominant polycystic kidney disease 4.8
Placental insufficiency 4.8
metabolic disorder 4.8
MIN 4.8
MIN 4.8
extrahepatic bile duct cancer 4.7
Subclinical hypothyroidism 4.7
ACS1 4.7
glucose intolerance 4.7
Wolff-Parkinson-White syndrome 4.7
Hajdu-Cheney syndrome 4.7
OFD1 4.6
dyslipidemia 4.6
Silence 4.6
more...
Symptom
stomach cramps 5.7
Cold intolerance 5.1
starvation 4.8
rundown 3.9
aphagia 3.6
cachexia 3.5
Cushingoid 3.5
Cushingoid 3.4
Anoxia 3.1
exhaustion 2.6
Scratch 2.6
memory loss 2.6
hunger 2.6
menopausal symptoms 2.6
functional recovery 2.5
stomach pain 2.3
POA 2.2
Decreased activity 2.2
Neuropathic pain 1.8
fatigue 1.6
anorexia 1.5
overweight 1.5
hypercapnia 1.5
neurological disability 1.4
collapse 1.3
hyperoxia 1.2
Hudson 1.2
muscle rigidity 1.2
decreased appetite 1.1
bradykinesia 1.1
pallor 0.9
acute pain 0.9
bitter taste 0.8
hypothermia 0.8
HSA 0.7
respiratory distress 0.7
skin damage 0.7
acute stress 0.7
incoordination 0.5
weakness 0.4
hepatomegaly 0.3
splenomegaly 0.3
chills 0.2
myalgia 0.2
polydipsia 0.1
dry eye -0.1
shoulder pain -0.2
low back pain -0.4
ophthalmoplegia -0.5
thinning -0.6
cyanosis -0.6
ataxia -0.7
angina -0.8
myoclonus -0.8
diarrhea -0.9
insomnia -1.1
Ill -1.2
seizures -1.2
pain -1.3
hypotonia -1.3
back pain -1.3
hemoptysis -1.3
anesthesia -1.3
tremor -1.3
spasticity -1.4
arthralgia -1.6
spasm -1.6
acidity -1.6
syncope -1.9
cough -2.3
agitation -2.3
stigma -2.5
abdominal pain -2.7
headache -2.9
discomfort -3.2
nausea -3.3
discomfort -3.3
dyspnea -3.5
analgesia -3.5
vomiting -3.7
more...
Drug
Benproperine phosphate 11.3
Aicar 11.3
Cassia seed 9.1
Acadesine 8.9
Adenosine Monophosphate 8.3
Fidarestat 7.4
Fidarestat 7.4
Ara-A 7.4
3-Methyladenine 7.2
Safingol 7.1
Metreleptin 6.9
1-Deoxynojirimycin 6.6
Crotonaldehyde 6.6
Liraglutide 6.5
Nelarabine 6.3
Aescin 6.2
Pramlintide 6.2
Glucose-6-Phosphate 6.0
Ciglitazone 6.0
Januvia 6.0
Parkin 5.8
Parkin 5.8
Mevastatin 5.8
Amlexanox 5.8
Rosiglitazone 5.8
Emodin 5.7
Adamantane 5.6
Vitamin K2 5.6
Penfluridol 5.6
Creosote 5.6
CTZ 5.5
Sesamol 5.4
Emodin 5.4
Troglitazone 5.4
ROS 5.3
Rosuvastatin calcium 5.3
metformin hydrochloride 5.3
Orlistat 5.2
Esculin 5.2
RFP 5.2
Cilostazol 5.2
Virginiamycin 5.1
Jujube 5.1
Omapatrilat 5.1
Ramelteon 4.9
Salicylate 4.9
Telbivudine 4.9
Cangrelor 4.9
Epigallocatechin 4.8
Ezetimibe 4.8
AMK 4.7
Insulin glargine 4.7
Ginseng 4.7
Coconut oil 4.6
Cinacalcet 4.6
Clove 4.6
AIC 4.5
Nexavar 4.5
Aricept 4.5
Exenatide 4.5
Sorafenib 4.5
Rimonabant 4.5
CMX 4.5
Artesunate 4.4
Red ginseng 4.4
Safflower 4.3
Celebrex 4.3
Ranolazine 4.3
Ranolazine 4.3
NAH 4.3
Rhubarb 4.2
Glucagon 4.2
Roflumilast 4.2
Roflumilast 4.2
Pemetrexed 4.2
Areca 4.2
Cilazapril 4.1
TAK 4.1
Glycyrrhiza 4.1
Sunitinib malate 4.1
more...
Enzyme
calpain C 11.3
AMP-activated protein kinase 11.3
AMPK 11.2
reductase phosphatase 10.7
AMPK 10.3
acetyl-CoA carboxylase 9.2
AMP-activated kinase 8.5
malonyl-CoA decarboxylase 8.4
phosphatidylinositol 3-phosphate 5-kinase 8.3
eEF2 kinase 8.0
carnitine O-octanoyltransferase 7.9
D-dopachrome tautomerase 7.8
STK11 7.8
retinol saturase 7.6
YeiK 7.4
gamma-glutamylcyclotransferase 7.3
hormone-sensitive lipase 6.7
CPT 6.7
nicotinamide phosphoribosyltransferase 6.5
alpha-1,4-glucan lyase 6.5
TOR 6.5
HK2 6.4
fatty-acid synthase 6.3
CPT 6.2
3-hydroxy-3-methylglutaryl-CoA reductase 6.2
triokinase 6.1
CaMKII 6.1
CPT 6.1
6-phosphofructo-2-kinase 6.0
PDK1 6.0
adenosine kinase 6.0
isochorismatase 6.0
sulfur dioxygenase 6.0
O-GlcNAc transferase 6.0
IMP cyclohydrolase 5.9
acetoacetyl-CoA synthetase 5.9
betaine-homocysteine methyltransferase 5.9
phosphatidylinositol-4,5-bisphosphate 3-kinase 5.9
glucose-6-phosphatase 5.9
DHOdehase 5.9
phosphoenolpyruvate carboxykinase 5.8
GK2 5.8
acyl-CoA oxidase 5.8
pyruvate dehydrogenase phosphatase 5.8
proprotein convertase 1 5.7
6-pyruvoyltetrahydropterin synthase 5.7
3-oxoacid CoA-transferase 5.7
citrate synthase 5.6
protein phosphatase 2A 5.6
glycine amidinotransferase 5.5
proline oxidase 5.5
type 1 protein phosphatase 5.5
AICAR transformylase 5.4
phosphoenolpyruvate carboxykinase 5.3
phosphoenolpyruvate carboxykinase 5.3
aggrecanase-1 5.3
protein kinase 5.3
cathepsin F 5.3
Tpt1 5.3
D-alanine:D-alanine ligase 5.2
palmitoyl-protein thioesterase 5.2
3-hydroxy-3-methylglutaryl coenzyme A reductase 5.2
glucokinase 5.2
Omi/HtrA2 5.2
retinal dehydrogenase 5.1
complex I 5.1
phosphatidate phosphatase 5.1
glycogenin 5.1
nicotinic acid phosphoribosyltransferase 5.1
glycogen synthase phosphatase 5.0
GSK 5.0
phosphoinositide 3-kinase 5.0
choline dehydrogenase 5.0
phosphatidylinositol 3-kinase 5.0
glycine N-methyltransferase 4.9
acyl-CoA dehydrogenase 4.9
ceramidase 4.9
6-phosphogluconolactonase 4.8
diacylglycerol acyltransferase 4.8
choline kinase 4.8
more...
Compound
Evoxine 11.3
AICAR 10.7
4-Bromodiphenyl ether 10.3
2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid 10.3
4-Bromodiphenyl ether 10.3
AICA-riboside 10.2
AICAR 9.9
Hernandezine 9.9
Aminoimidazole 9.8
Oxyphenisatin 9.7
Scirpusin A 9.7
2,5-dichlorobenzenesulfonamide 9.3
Deuterohemin 9.3
Ginkgolide C 9.3
Deuterohemin 9.3
Saponarin 9.1
Tubeimoside I 8.9
Justicidin A 8.9
9H-xanthene-9-carboxylic acid 8.9
Tephrosin 8.9
Batatasin I 8.9
Metformin 8.7
Metformin 8.7
Gartanin 8.7
Wuweizisu C 8.7
Hispidulin 8.6
methyl dihydrogen phosphate 8.4
Sinensetin 8.4
Jervine 8.4
p-Synephrine 8.3
Ginkgolide C 8.3
Panaxatriol 8.3
Prunetin 8.1
Scopolin 8.1
Karanjin 7.9
Petasin 7.9
Pinosylvin 7.9
Pinosylvin 7.9
Wedelolactone 7.8
Methyl cinnamate 7.8
Taraxerol 7.8
Narirutin 7.8
Taraxerol 7.8
5-Iodotubercidin 7.7
Chebulagic acid 7.7
Dihydromyricetin 7.7
5-Iodotubercidin 7.7
Isoorientin 7.7
Chebulagic acid 7.7
5-Iodotubercidin 7.7
Tuberin 7.6
Soraphen A 7.6
Fagomine 7.6
5-Iodotubercidin 7.6
Biguanide 7.4
Acetylshikonin 7.4
DBI 7.4
Kaempferide 7.3
Dehydrozingerone 7.3
1'-Acetoxychavicol acetate 7.3
Physcion 7.2
3-Methyladenine 7.2
malonyl-CoA 7.2
Rhaponticin 7.2
Norathyriol 7.2
Endothall 7.2
Gallein 7.2
Chrysophanol 7.1
Buformin 7.1
Gallein 7.1
Chrysophanol 7.1
Catalpol 7.0
Berberine 7.0
Eupafolin 7.0
Isoquercitrin 7.0
Capsanthin 7.0
Deoxypodophyllotoxin 7.0
Deguelin 6.9
TSC 6.9
Coniferaldehyde 6.9
more...