Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:2.7.11.31 (AMP-activated protein kinase)
13,065 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein AMP-activated protein kinase 7316 AMPK 6226 insulin 2471 mTOR 1962 ATP 1507 Mol 1347 AMP 866 Sep 711 LKB1 683 acetyl-CoA carboxylase 678 adiponectin 647 AKT 559 PGC 534 AICAR 532 PI3K 500 peroxisome proliferator-activated receptor 485 p53 432 LC3 413 MAPK 412 SIRT1 392 p38 391 leptin 391 TNF 347 caspase-3 347 endoplasmic reticulum 337 ROS 308 GLUT4 305 p62 295 ERK 284 fatty acid synthase 282 ACC 281 ULK1 271 cytokine 257 JNK 256 IL-6 243 Adiponectin 241 ERK1 238 Bcl-2 234 protein kinase B 233 IRS-1 218 glucose transporter 212 calmodulin 211 tumor necrosis factor 210 Beclin-1 208 peroxisome proliferator-activated receptor gamma 199 PPAR 196 lipopolysaccharide 183 ADP 174 glucagon 172 sirtuin 1 168 threonine 168 superoxide dismutase 163 Nrf2 161 p21 156 NAD 149 phosphatase 149 serine/threonine kinase 147 S6K1 143 inducible nitric oxide synthase 142 phosphatidylinositol 3-kinase 141 collagen 139 PKA 137 adipokine 134 endothelial nitric oxide synthase 133 ubiquitin 128 gut 127 eNOS 126 glucose transporter 4 123 sterol regulatory element-binding protein 123 epididymal 122 STAT3 120 CaMKII 119 uncoupling protein 1 118 LPS 117 CD36 117 catalase 115 insulin receptor 113 LC3B 111 erythroid 110 FAS 109 more...

Disease cancer 1860 obesity 1475 diabetes 1310 tumor 1077 type 2 diabetes 927 fatty liver 434 hyperglycemia 353 ischemia 334 metabolic syndrome 306 breast cancer 283 hepatocellular carcinoma 281 tumor growth 264 atherosclerosis 215 Alzheimer's disease 198 tumorigenesis 194 hypertension 181 cardiovascular disease 174 heart failure 155 hyperlipidemia 148 dyslipidemia 142 prostate cancer 136 myocardial ischemia 129 lung cancer 126 glucose intolerance 126 tumor progression 122 stroke 121 colorectal cancer 120 carcinogenesis 113 FAS 111 alcoholic fatty liver 110 Parkinson's disease 105 myocardial infarction 104 GSH 97 carcinoma 96 tuberous sclerosis 92 colon cancer 91 diabetic nephropathy 81 liver disease 80 MCF 80 sepsis 77 sepsis 77 adenocarcinoma 76 neuroblastoma 75 hypoglycemia 74 Nonalcoholic fatty liver 73 pancreatic cancer 72 cold 72 melanoma 70 leukemia 70 hyperinsulinemia 69 ATM 68 non-small cell lung cancer 66 glioma 65 depression 65 cardiomyopathy 64 glioblastoma 62 cerebral ischemia 60 metabolic disorder 57 ovarian cancer 56 cognitive impairment 55 liver cancer 51 gastric cancer 50 diabetic cardiomyopathy 49 NAME 47 type 1 diabetes 44 Blocking 43 muscular atrophy 43 plaque 43 liver fibrosis 42 colitis 42 osteoporosis 42 osteoarthritis 42 metastases 42 acute myeloid leukemia 42 liver cancer 42 squamous cell carcinoma 41 dementia 40 heart disease 39 Huntington's disease 38 polycystic ovary syndrome 38 more...

Symptom starvation 285 fatigue 64 pain 45 exhaustion 35 functional recovery 31 overweight 30 collapse 29 cachexia 27 weakness 20 anesthesia 18 anorexia 16 hunger 14 seizures 14 diarrhea 13 respiratory distress 13 hypothermia 12 hypercapnia 9 memory loss 9 angina 5 splenomegaly 5 hyperoxia 5 menopausal symptoms 4 ataxia 4 acute stress 3 rundown 3 thinning 3 hepatomegaly 3 acute pain 3 low back pain 3 myalgia 3 tremor 3 headache 3 pallor 2 Ill 2 bradykinesia 2 Anoxia 2 chills 2 insomnia 2 Neuropathic pain 2 back pain 2 HSA 2 cough 2 abdominal pain 2 acidity 2 Scratch 1 skin damage 1 incoordination 1 dyspnea 1 Hudson 1 Cushingoid 1 Cushingoid 1 vomiting 1 analgesia 1 stigma 1 spasm 1 stomach cramps 1 decreased appetite 1 shoulder pain 1 bitter taste 1 arthralgia 1 hypotonia 1 syncope 1 dry eye 1 discomfort 1 discomfort 1 muscle rigidity 1 spasticity 1 polydipsia 1 hemoptysis 1 myoclonus 1 nausea 1 agitation 1 Cold intolerance 1 ophthalmoplegia 1 aphagia 1 stomach pain 1 neurological disability 1 Decreased activity 1 POA 1 cyanosis 1 more...

Drug ROS 308 NADH 67 lysine 54 Cardiovasc 45 Parkin 44 Parkin 44 caffeine 39 Ethanol 33 Glucagon 29 Monit 26 Rosiglitazone 18 RFP 18 Angiotensin II 17 Ginseng 17 MAP 16 Liraglutide 16 citric acid 15 ascorbate 14 Sorafenib 14 vitamin E 13 Fructose 13 Kenyan 11 EE2 11 Emodin 10 CSF 10 Emodin 10 Glycyrrhiza 10 Simvastatin 10 3-Methyladenine 10 Dermatol 9 IL-2 9 Troglitazone 9 EPA 9 Ara-A 8 CAM 8 Bifidobacterium 8 TAK 7 Forskolin 7 ALA 7 Lovastatin 7 Salicylate 7 Itraconazole 6 Leaf 6 Orlistat 6 Cilostazol 6 Nephron 6 Acadesine 6 DM1 5 GEO 5 IFN-gamma 5 Epigallocatechin 5 -deoxyadenosine 5 Pravastatin 5 Nitric Oxide 5 Methylene blue 5 ROC 5 balanced salt solution 5 Arsenic trioxide 5 MRC 5 Adriamycin 5 AIC 5 Ezetimibe 5 lactose 4 Docetaxel 4 Indomethacin 4 CoCl2 4 Gefitinib 4 CoCl2 4 niacin 4 Portal 4 Adenosine Monophosphate 4 ADM 4 Gel 4 Bupivacaine 4 metformin hydrochloride 4 Growth hormone 4 Growth hormone 4 Retinoic acid 4 Adenosine triphosphate 4 Rimonabant 3 more...

Enzyme AMP-activated protein kinase 13065 AMPK 6254 AMPK 6228 protein kinase 1285 mitogen-activated protein kinase 1050 acetyl-CoA carboxylase 709 ERK 407 caspase-3 243 superoxide dismutase 230 focal adhesion kinase 213 CPT 198 protein kinase C 195 calcineurin 155 phosphatidylinositol 3-kinase 141 alanine aminotransferase 141 aspartate aminotransferase 128 catalase 128 complex I 127 PARP 115 CaMKII 114 ATPase 114 phosphoenolpyruvate carboxykinase 109 proteasome 109 MEK 101 CPT 97 CPT 97 hormone-sensitive lipase 95 lactate dehydrogenase 92 luciferase 92 NO synthase 91 GSK 91 citrate synthase 88 glucose-6-phosphatase 76 phosphoinositide 3-kinase 76 NADPH oxidase 71 AMP-activated kinase 69 phosphoenolpyruvate carboxykinase 68 phosphoenolpyruvate carboxykinase 68 NADPH oxidase 66 lipoprotein lipase 60 PDK1 60 protein phosphatase 2A 59 lipase 57 TOR 54 glutathione peroxidase 52 IKK 50 AST 48 creatine kinase 48 peroxidase 47 hexokinase 43 STK11 43 caspase-9 43 alkaline phosphatase 42 glucokinase 42 pyruvate dehydrogenase 41 pyruvate kinase 41 caspase-1 41 glutathione S-transferase 40 ATP synthase 40 heme oxygenase 38 NOS 38 NQO1 36 phosphorylase 36 renin 35 succinate dehydrogenase 33 pyruvate dehydrogenase 33 pyruvate dehydrogenase 33 3-hydroxy-3-methylglutaryl-CoA reductase 33 phosphofructokinase 32 glyceraldehyde-3-phosphate dehydrogenase 30 phosphodiesterase 27 phospholipase C 27 cytochrome oxidase 26 eEF2 kinase 25 adenosine kinase 25 adenylate cyclase 24 PKG 24 3-hydroxy-3-methylglutaryl coenzyme A reductase 22 aldehyde dehydrogenase 22 acyl-CoA oxidase 22 more...

Compound glucose 3341 ATP 1507 oxygen 1215 AMP 949 Dec 808 AICAR 600 Metformin 584 Metformin 583 DNA 568 AICAR 547 threonine 474 calcium 446 TNF 347 water 277 serine 272 nitric oxide 270 phosphate 265 Clin 254 Insulin 251 cAMP 222 CoA 215 ADP 186 ethanol 183 NAD 183 adenylate 179 ADP 174 ADP 174 sodium 163 Guo 152 NAD 149 Resveratrol 146 palmitic acid 138 galactose 129 tyrosine 121 malonyl-CoA 113 arginine 112 hydrogen 111 MTT 111 cysteine 109 leucine 108 MDA 105 CPT 97 GSH 97 CPT 97 GSH 97 palmitic acid 94 nicotinamide 91 acetate 91 alanine 84 glutamate 83 glutamine 83 methionine 83 nitrogen 83 glycerol 79 Cardiol 78 N-acetylcysteine 74 lysine 74 MEK 71 acetyl-CoA 69 salt 68 NADH 67 Berberine 66 urea 60 cGMP 59 Rapamycin 59 THP 58 THP 58 Oil Red O 58 STZ 55 NADPH 55 NADPH 55 Oil Red O 55 H2O2 54 pentose 53 pentose 53 pentose 53 pentose 53 iron 50 Curcumin 47 Ang II 47 more...

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