Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.31 (AMP-activated protein kinase)
 13,065 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
phosphodiesterase 3B, cGMP-inhibited 11.3
KIAA0173 11.3
CEBPD protein 11.3
LONP 11.3
phosphoinositide-3-kinase adaptor protein 1 11.3
peroxisomal biogenesis factor 3 11.3
mitochondrial translation optimization 1 homolog 11.3
GRIK2 protein 11.3
PRO1853 11.3
AMPK beta 1 11.3
proline rich 5 11.3
WD repeat domain 24 11.3
DNM1L protein 11.3
C12orf73 11.3
AMPK 11.3
AMP-activated protein kinase 11.2
AICAR 10.7
protein kinase, AMP-activated, gamma 2 non-catalytic subunit 10.7
CAMKK 10.7
LC27 10.7
ampk 10.6
PRKAG1 10.5
CaMKK 10.5
PRKAA 10.4
LKB1 10.3
NUAK2 10.3
mitogen-activated protein kinase associated protein 1 10.3
TBC1 domain family member 1 10.3
WD repeat-containing protein 35 10.3
SSTK 10.3
6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase 10.3
WD repeat and FYVE domain containing 3 10.3
PRKAA2 10.3
NSPL1 10.3
TBC1D1 protein 10.3
TBC1D7 protein 10.3
ubiquitin specific peptidase 10 10.3
GLB1L 10.3
Rab40A 10.3
BR serine/threonine kinase 1 10.3
more...
Disease
Female hypogonadism 10.3
CCAL1 9.7
Amino acid deficiency 9.3
SAMS 8.8
poor fetal development 8.3
Infantile diarrhea 8.1
ATP synthase deficiency 7.6
Secretory diarrhea 7.5
EBSS 7.3
muscle cancer 7.3
EPM2B 7.1
IMD1 7.1
BHD 7.0
Hypophagia 6.9
BHD 6.9
liver scarring 6.9
female subfertility 6.8
Multiple cancer 6.8
Diabetic encephalopathy 6.6
Peutz-Jeghers syndrome 6.6
fatty liver 6.2
alcoholic fatty liver 6.2
diabetic cardiomyopathy 6.2
FAS 6.1
AML progression 6.0
Hypoxic-ischemic encephalopathy (HIE) 5.9
WTS 5.9
Bateman 5.8
MODY1 5.8
Fulminant hepatitis 5.8
NEK1 5.8
Sepsis-associated encephalopathy 5.7
SCD 5.7
adult brain tumor 5.7
Nonalcoholic fatty liver 5.7
Simpson-Golabi-Behmel syndrome 5.7
OPA1 5.7
Congenital nephrogenic diabetes insipidus 5.6
Hers 5.6
Cancer cachexia 5.6
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Symptom
stomach cramps 5.7
Cold intolerance 5.1
starvation 4.8
rundown 3.9
aphagia 3.6
cachexia 3.5
Cushingoid 3.5
Cushingoid 3.4
Anoxia 3.1
exhaustion 2.6
Scratch 2.6
memory loss 2.6
hunger 2.6
menopausal symptoms 2.6
functional recovery 2.5
stomach pain 2.3
POA 2.2
Decreased activity 2.2
Neuropathic pain 1.8
fatigue 1.6
anorexia 1.5
overweight 1.5
hypercapnia 1.5
neurological disability 1.4
collapse 1.3
hyperoxia 1.2
Hudson 1.2
muscle rigidity 1.2
decreased appetite 1.1
bradykinesia 1.1
pallor 0.9
acute pain 0.9
bitter taste 0.8
hypothermia 0.8
HSA 0.7
respiratory distress 0.7
skin damage 0.7
acute stress 0.7
incoordination 0.5
weakness 0.4
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Drug
Aicar 11.3
Benproperine phosphate 11.3
Cassia seed 9.1
Acadesine 8.9
Adenosine Monophosphate 8.3
Fidarestat 7.4
Fidarestat 7.4
Ara-A 7.4
3-Methyladenine 7.2
Safingol 7.1
Metreleptin 6.9
1-Deoxynojirimycin 6.6
Crotonaldehyde 6.6
Liraglutide 6.5
Nelarabine 6.3
Pramlintide 6.2
Aescin 6.2
Ciglitazone 6.0
Januvia 6.0
Glucose-6-Phosphate 6.0
Parkin 5.8
Parkin 5.8
Mevastatin 5.8
Amlexanox 5.8
Rosiglitazone 5.8
Emodin 5.7
Adamantane 5.6
Vitamin K2 5.6
Penfluridol 5.6
Creosote 5.6
CTZ 5.5
Sesamol 5.4
Emodin 5.4
Troglitazone 5.4
ROS 5.3
Rosuvastatin calcium 5.3
metformin hydrochloride 5.3
Orlistat 5.2
Esculin 5.2
RFP 5.2
more...
Enzyme
calpain C 11.3
AMP-activated protein kinase 11.3
AMPK 11.2
reductase phosphatase 10.7
AMPK 10.3
acetyl-CoA carboxylase 9.2
AMP-activated kinase 8.5
malonyl-CoA decarboxylase 8.4
phosphatidylinositol 3-phosphate 5-kinase 8.3
eEF2 kinase 8.0
carnitine O-octanoyltransferase 7.9
D-dopachrome tautomerase 7.8
STK11 7.8
retinol saturase 7.6
YeiK 7.4
gamma-glutamylcyclotransferase 7.3
hormone-sensitive lipase 6.7
CPT 6.7
nicotinamide phosphoribosyltransferase 6.5
alpha-1,4-glucan lyase 6.5
TOR 6.5
HK2 6.4
fatty-acid synthase 6.3
CPT 6.2
3-hydroxy-3-methylglutaryl-CoA reductase 6.2
triokinase 6.1
CaMKII 6.1
CPT 6.1
6-phosphofructo-2-kinase 6.0
PDK1 6.0
adenosine kinase 6.0
sulfur dioxygenase 6.0
isochorismatase 6.0
O-GlcNAc transferase 6.0
betaine-homocysteine methyltransferase 5.9
phosphatidylinositol-4,5-bisphosphate 3-kinase 5.9
IMP cyclohydrolase 5.9
acetoacetyl-CoA synthetase 5.9
glucose-6-phosphatase 5.9
DHOdehase 5.9
more...
Compound
Evoxine 11.3
AICAR 10.7
2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid 10.3
4-Bromodiphenyl ether 10.3
4-Bromodiphenyl ether 10.3
AICA-riboside 10.2
AICAR 9.9
Hernandezine 9.9
Aminoimidazole 9.8
Scirpusin A 9.7
Oxyphenisatin 9.7
Deuterohemin 9.3
2,5-dichlorobenzenesulfonamide 9.3
Ginkgolide C 9.3
Deuterohemin 9.3
Saponarin 9.1
Tephrosin 8.9
Tubeimoside I 8.9
9H-xanthene-9-carboxylic acid 8.9
Batatasin I 8.9
Justicidin A 8.9
Metformin 8.7
Metformin 8.7
Wuweizisu C 8.7
Gartanin 8.7
Hispidulin 8.6
Jervine 8.4
methyl dihydrogen phosphate 8.4
Sinensetin 8.4
Ginkgolide C 8.3
p-Synephrine 8.3
Panaxatriol 8.3
Scopolin 8.1
Prunetin 8.1
Karanjin 7.9
Petasin 7.9
Pinosylvin 7.9
Pinosylvin 7.9
Methyl cinnamate 7.8
Narirutin 7.8
more...