Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:2.7.11.31 (AMP-activated protein kinase)
13,065 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein AMP-activated protein kinase 7316 AMPK 6226 insulin 2471 mTOR 1962 ATP 1507 Mol 1347 AMP 866 Sep 711 LKB1 683 acetyl-CoA carboxylase 678 adiponectin 647 AKT 559 PGC 534 AICAR 532 PI3K 500 peroxisome proliferator-activated receptor 485 p53 432 LC3 413 MAPK 412 SIRT1 392 leptin 391 p38 391 caspase-3 347 TNF 347 endoplasmic reticulum 337 ROS 308 GLUT4 305 p62 295 ERK 284 fatty acid synthase 282 ACC 281 ULK1 271 cytokine 257 JNK 256 IL-6 243 Adiponectin 241 ERK1 238 Bcl-2 234 protein kinase B 233 IRS-1 218 more...

Disease cancer 1860 obesity 1475 diabetes 1310 tumor 1077 type 2 diabetes 927 fatty liver 434 hyperglycemia 353 ischemia 334 metabolic syndrome 306 breast cancer 283 hepatocellular carcinoma 281 tumor growth 264 atherosclerosis 215 Alzheimer's disease 198 tumorigenesis 194 hypertension 181 cardiovascular disease 174 heart failure 155 hyperlipidemia 148 dyslipidemia 142 prostate cancer 136 myocardial ischemia 129 glucose intolerance 126 lung cancer 126 tumor progression 122 stroke 121 colorectal cancer 120 carcinogenesis 113 FAS 111 alcoholic fatty liver 110 Parkinson's disease 105 myocardial infarction 104 GSH 97 carcinoma 96 tuberous sclerosis 92 colon cancer 91 diabetic nephropathy 81 liver disease 80 MCF 80 sepsis 77 more...

Symptom starvation 285 fatigue 64 pain 45 exhaustion 35 functional recovery 31 overweight 30 collapse 29 cachexia 27 weakness 20 anesthesia 18 anorexia 16 hunger 14 seizures 14 respiratory distress 13 diarrhea 13 hypothermia 12 memory loss 9 hypercapnia 9 hyperoxia 5 angina 5 splenomegaly 5 menopausal symptoms 4 ataxia 4 acute stress 3 low back pain 3 rundown 3 thinning 3 hepatomegaly 3 myalgia 3 tremor 3 acute pain 3 headache 3 pallor 2 cough 2 Anoxia 2 insomnia 2 chills 2 Neuropathic pain 2 Ill 2 back pain 2 more...

Drug ROS 308 NADH 67 lysine 54 Cardiovasc 45 Parkin 44 Parkin 44 caffeine 39 Ethanol 33 Glucagon 29 Monit 26 RFP 18 Rosiglitazone 18 Angiotensin II 17 Ginseng 17 MAP 16 Liraglutide 16 citric acid 15 Sorafenib 14 ascorbate 14 vitamin E 13 Fructose 13 EE2 11 Kenyan 11 Emodin 10 Simvastatin 10 3-Methyladenine 10 Glycyrrhiza 10 Emodin 10 CSF 10 IL-2 9 EPA 9 Dermatol 9 Troglitazone 9 Ara-A 8 Bifidobacterium 8 CAM 8 TAK 7 Lovastatin 7 Salicylate 7 ALA 7 more...

Enzyme AMP-activated protein kinase 13065 AMPK 6254 AMPK 6228 protein kinase 1285 mitogen-activated protein kinase 1050 acetyl-CoA carboxylase 709 ERK 407 caspase-3 243 superoxide dismutase 230 focal adhesion kinase 213 CPT 198 protein kinase C 195 calcineurin 155 alanine aminotransferase 141 phosphatidylinositol 3-kinase 141 catalase 128 aspartate aminotransferase 128 complex I 127 PARP 115 CaMKII 114 ATPase 114 phosphoenolpyruvate carboxykinase 109 proteasome 109 MEK 101 CPT 97 CPT 97 hormone-sensitive lipase 95 luciferase 92 lactate dehydrogenase 92 GSK 91 NO synthase 91 citrate synthase 88 glucose-6-phosphatase 76 phosphoinositide 3-kinase 76 NADPH oxidase 71 AMP-activated kinase 69 phosphoenolpyruvate carboxykinase 68 phosphoenolpyruvate carboxykinase 68 NADPH oxidase 66 PDK1 60 more...

Compound glucose 3341 ATP 1507 oxygen 1215 AMP 949 Dec 808 AICAR 600 Metformin 584 Metformin 583 DNA 568 AICAR 547 threonine 474 calcium 446 TNF 347 water 277 serine 272 nitric oxide 270 phosphate 265 Clin 254 Insulin 251 cAMP 222 CoA 215 ADP 186 ethanol 183 NAD 183 adenylate 179 ADP 174 ADP 174 sodium 163 Guo 152 NAD 149 Resveratrol 146 palmitic acid 138 galactose 129 tyrosine 121 malonyl-CoA 113 arginine 112 MTT 111 hydrogen 111 cysteine 109 leucine 108 more...

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