Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.31 (AMP-activated protein kinase)
13,065 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
AMP-activated protein kinase 7316
AMPK 6226
insulin 2471
mTOR 1962
ATP 1507
Mol 1347
AMP 866
Sep 711
LKB1 683
acetyl-CoA carboxylase 678
adiponectin 647
AKT 559
PGC 534
AICAR 532
PI3K 500
peroxisome proliferator-activated receptor 485
p53 432
LC3 413
MAPK 412
SIRT1 392
more...
Disease
cancer 1860
obesity 1475
diabetes 1310
tumor 1077
type 2 diabetes 927
fatty liver 434
hyperglycemia 353
ischemia 334
metabolic syndrome 306
breast cancer 283
hepatocellular carcinoma 281
tumor growth 264
atherosclerosis 215
Alzheimer's disease 198
tumorigenesis 194
hypertension 181
cardiovascular disease 174
heart failure 155
hyperlipidemia 148
dyslipidemia 142
more...
Symptom
starvation 285
fatigue 64
pain 45
exhaustion 35
functional recovery 31
overweight 30
collapse 29
cachexia 27
weakness 20
anesthesia 18
anorexia 16
hunger 14
seizures 14
diarrhea 13
respiratory distress 13
hypothermia 12
hypercapnia 9
memory loss 9
angina 5
hyperoxia 5
more...
Drug
ROS 308
NADH 67
lysine 54
Cardiovasc 45
Parkin 44
Parkin 44
caffeine 39
Ethanol 33
Glucagon 29
Monit 26
RFP 18
Rosiglitazone 18
Angiotensin II 17
Ginseng 17
MAP 16
Liraglutide 16
citric acid 15
ascorbate 14
Sorafenib 14
vitamin E 13
more...
Enzyme
AMP-activated protein kinase 13065
AMPK 6254
AMPK 6228
protein kinase 1285
mitogen-activated protein kinase 1050
acetyl-CoA carboxylase 709
ERK 407
caspase-3 243
superoxide dismutase 230
focal adhesion kinase 213
CPT 198
protein kinase C 195
calcineurin 155
phosphatidylinositol 3-kinase 141
alanine aminotransferase 141
aspartate aminotransferase 128
catalase 128
complex I 127
PARP 115
CaMKII 114
more...
Compound
glucose 3341
ATP 1507
oxygen 1215
AMP 949
Dec 808
AICAR 600
Metformin 584
Metformin 583
DNA 568
AICAR 547
threonine 474
calcium 446
TNF 347
water 277
serine 272
nitric oxide 270
phosphate 265
Clin 254
Insulin 251
cAMP 222
more...