Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.11.31 (
AMP-activated protein kinase
)
13,065
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
AMP-activated protein kinase
7316
AMPK
6226
insulin
2471
mTOR
1962
ATP
1507
Mol
1347
AMP
866
Sep
711
LKB1
683
acetyl-CoA carboxylase
678
adiponectin
647
AKT
559
PGC
534
AICAR
532
PI3K
500
peroxisome proliferator-activated receptor
485
p53
432
LC3
413
MAPK
412
SIRT1
392
more...
Disease
cancer
1860
obesity
1475
diabetes
1310
tumor
1077
type 2 diabetes
927
fatty liver
434
hyperglycemia
353
ischemia
334
metabolic syndrome
306
breast cancer
283
hepatocellular carcinoma
281
tumor growth
264
atherosclerosis
215
Alzheimer's disease
198
tumorigenesis
194
hypertension
181
cardiovascular disease
174
heart failure
155
hyperlipidemia
148
dyslipidemia
142
more...
Symptom
starvation
285
fatigue
64
pain
45
exhaustion
35
functional recovery
31
overweight
30
collapse
29
cachexia
27
weakness
20
anesthesia
18
anorexia
16
hunger
14
seizures
14
diarrhea
13
respiratory distress
13
hypothermia
12
hypercapnia
9
memory loss
9
angina
5
hyperoxia
5
more...
Drug
ROS
308
NADH
67
lysine
54
Cardiovasc
45
Parkin
44
Parkin
44
caffeine
39
Ethanol
33
Glucagon
29
Monit
26
RFP
18
Rosiglitazone
18
Angiotensin II
17
Ginseng
17
MAP
16
Liraglutide
16
citric acid
15
ascorbate
14
Sorafenib
14
vitamin E
13
more...
Enzyme
AMP-activated protein kinase
13065
AMPK
6254
AMPK
6228
protein kinase
1285
mitogen-activated protein kinase
1050
acetyl-CoA carboxylase
709
ERK
407
caspase-3
243
superoxide dismutase
230
focal adhesion kinase
213
CPT
198
protein kinase C
195
calcineurin
155
phosphatidylinositol 3-kinase
141
alanine aminotransferase
141
aspartate aminotransferase
128
catalase
128
complex I
127
PARP
115
CaMKII
114
more...
Compound
glucose
3341
ATP
1507
oxygen
1215
AMP
949
Dec
808
AICAR
600
Metformin
584
Metformin
583
DNA
568
AICAR
547
threonine
474
calcium
446
TNF
347
water
277
serine
272
nitric oxide
270
phosphate
265
Clin
254
Insulin
251
cAMP
222
more...