Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:2.7.11.27 (AMPK)
6,299 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein AMPK 6226 mTOR 1249 insulin 1082 Mol 637 ATP 582 AMP-activated protein kinase 511 PI3K 410 AKT 401 LKB1 382 PGC 329 adiponectin 309 Sep 305 AMP 304 LC3 298 MAPK 290 SIRT1 290 p53 267 ROS 247 AICAR 235 TNF 233 ACC 214 ULK1 206 caspase-3 205 ERK 203 p62 197 p38 197 JNK 173 endoplasmic reticulum 165 GLUT4 162 leptin 159 Bcl-2 157 IL-6 157 Beclin-1 150 acetyl-CoA carboxylase 149 peroxisome proliferator-activated receptor 138 Nrf2 135 PPAR 135 ERK1 122 cytokine 122 IRS-1 106 eNOS 98 Adiponectin 98 PKA 95 FAS 95 S6K1 90 superoxide dismutase 87 STAT3 87 fatty acid synthase 85 p21 83 inducible nitric oxide synthase 83 lipopolysaccharide 80 LC3B 79 gut 79 TSC2 77 tumor necrosis factor 77 collagen 77 ubiquitin 77 glucagon 75 NAD 74 PDB 70 adipokine 69 PARP 69 SREBP-1 69 LPS 68 PKC 68 proteasome 66 CD36 66 glucose transporter 65 SREBP-1c 65 ADP 65 FRAP 65 CREB 64 PTEN 64 CPT 63 SOD 63 epididymal 62 HO-1 62 GSH 61 phosphatase 60 threonine 60 more...

Disease cancer 1080 obesity 644 tumor 615 diabetes 593 type 2 diabetes 375 fatty liver 204 breast cancer 173 hyperglycemia 166 tumor growth 162 hepatocellular carcinoma 147 ischemia 141 tumorigenesis 123 metabolic syndrome 123 Alzheimer's disease 111 atherosclerosis 105 FAS 97 hypertension 83 prostate cancer 82 lung cancer 82 cardiovascular disease 81 tumor progression 74 colorectal cancer 74 hyperlipidemia 72 heart failure 71 dyslipidemia 68 glucose intolerance 66 stroke 63 GSH 61 myocardial ischemia 60 alcoholic fatty liver 59 myocardial infarction 58 carcinogenesis 58 carcinoma 55 Parkinson's disease 54 ATM 53 adenocarcinoma 52 pancreatic cancer 45 MCF 45 non-small cell lung cancer 43 tuberous sclerosis 43 colon cancer 42 melanoma 41 glioblastoma 40 diabetic nephropathy 40 leukemia 39 glioma 39 liver disease 38 cold 35 sepsis 35 sepsis 35 cerebral ischemia 33 liver cancer 33 ovarian cancer 32 metabolic disorder 32 neuroblastoma 31 liver fibrosis 31 hypoglycemia 29 NAME 29 gastric cancer 29 liver cancer 28 cognitive impairment 27 acute myeloid leukemia 27 colitis 26 cardiomyopathy 26 renal cell carcinoma 26 Nonalcoholic fatty liver 26 diabetic cardiomyopathy 25 osteoporosis 25 muscular atrophy 25 depression 24 hyperinsulinemia 24 osteosarcoma 23 sickle cell disease 23 Peutz-Jeghers syndrome 23 Huntington's disease 22 dementia 22 squamous cell carcinoma 22 plaque 21 osteoarthritis 21 metastases 21 more...

Symptom starvation 139 fatigue 29 pain 25 functional recovery 21 collapse 21 overweight 20 exhaustion 18 cachexia 14 weakness 10 hunger 10 anesthesia 9 memory loss 8 diarrhea 7 respiratory distress 6 hypothermia 6 hypercapnia 4 seizures 4 anorexia 4 hyperoxia 3 thinning 3 low back pain 3 acute pain 2 hepatomegaly 2 chills 2 angina 2 insomnia 2 Neuropathic pain 2 cough 2 menopausal symptoms 2 ataxia 2 tremor 2 back pain 2 pallor 2 bradykinesia 2 vomiting 1 stigma 1 abdominal pain 1 Anoxia 1 stomach cramps 1 syncope 1 muscle rigidity 1 myalgia 1 spasticity 1 nausea 1 shoulder pain 1 bitter taste 1 ophthalmoplegia 1 cyanosis 1 HSA 1 acidity 1 dyspnea 1 Cushingoid 1 hemoptysis 1 POA 1 rundown 1 headache 1 Scratch 1 Ill 1 skin damage 1 neurological disability 1 Cushingoid 1

Drug ROS 247 NADH 32 Parkin 28 Parkin 28 lysine 27 Monit 21 Cardiovasc 17 MAP 13 RFP 13 Ethanol 12 caffeine 12 Liraglutide 11 Ginseng 11 ascorbate 10 Glucagon 10 Rosiglitazone 10 Dermatol 9 CSF 8 Sorafenib 7 vitamin E 7 EE2 7 3-Methyladenine 7 citric acid 6 ALA 6 Glycyrrhiza 5 Angiotensin II 5 Simvastatin 5 Ara-A 5 Arsenic trioxide 5 TAK 5 Itraconazole 5 Orlistat 4 Bifidobacterium 4 Ezetimibe 4 Kenyan 4 EPA 4 Troglitazone 4 Salicylate 4 Acadesine 4 Adenosine Monophosphate 4 Emodin 4 Docetaxel 4 Emodin 4 Portal 4 Fructose 3 Forskolin 3 Artesunate 3 balanced salt solution 3 Imatinib 3 MDS 3 DM1 3 TAC 3 niacin 3 Exenatide 3 Glycerol 3 GEO 3 Methylene blue 3 Vitamin K2 3 Nitric Oxide 3 ROC 3 IL-11 2 uPA 2 Dasatinib 2 Heme 2 Retinoic acid 2 DHT 2 Fidarestat 2 Pramlintide 2 ETA 2 metformin hydrochloride 2 Triclosan 2 Fidarestat 2 PTC 2 Luteinizing 2 Sesamol 2 Cilostazol 2 CCL 2 PCB 2 MRC 2 Bupivacaine 2 more...

Enzyme AMPK 6299 AMP-activated protein kinase 6228 AMPK 6226 protein kinase 697 mitogen-activated protein kinase 570 ERK 304 focal adhesion kinase 199 acetyl-CoA carboxylase 155 superoxide dismutase 142 caspase-3 140 CPT 94 protein kinase C 86 alanine aminotransferase 82 PARP 79 catalase 74 aspartate aminotransferase 71 proteasome 67 CPT 63 complex I 63 CPT 63 MEK 57 phosphoenolpyruvate carboxykinase 56 GSK 53 ATPase 52 citrate synthase 48 TOR 47 luciferase 47 lactate dehydrogenase 46 calcineurin 46 CaMKII 44 hormone-sensitive lipase 44 phosphatidylinositol 3-kinase 38 AST 37 PDK1 35 glutathione peroxidase 32 NADPH oxidase 31 NADPH oxidase 31 AMP-activated kinase 30 IKK 30 caspase-1 28 peroxidase 27 phosphoenolpyruvate carboxykinase 25 phosphoenolpyruvate carboxykinase 25 alkaline phosphatase 25 creatine kinase 25 lipase 24 ATP synthase 24 STK11 24 NQO1 24 NO synthase 23 caspase-9 22 NOS 22 glyceraldehyde-3-phosphate dehydrogenase 21 glucose-6-phosphatase 21 glutathione S-transferase 19 ACE 19 pyruvate dehydrogenase 18 hexokinase 17 protein phosphatase 2A 17 PKG 17 phosphoinositide 3-kinase 17 phosphofructokinase 16 renin 15 succinate dehydrogenase 15 heme oxygenase 15 lipoprotein lipase 15 HK2 15 pyruvate dehydrogenase 14 aldehyde dehydrogenase 14 glucokinase 14 glucose-6-phosphate dehydrogenase 14 glyceraldehyde-3-phosphate dehydrogenase 14 pyruvate dehydrogenase 14 cytochrome oxidase 13 aldehyde dehydrogenase 12 glyceraldehyde-3-phosphate dehydrogenase 12 glyceraldehyde-3-phosphate dehydrogenase 12 aldehyde dehydrogenase 12 glyceraldehyde-3-phosphate dehydrogenase 12 aldehyde dehydrogenase 12 more...

Compound glucose 1397 oxygen 588 ATP 582 AMP 373 Dec 355 DNA 315 Metformin 284 Metformin 284 AICAR 249 AICAR 237 TNF 233 calcium 218 threonine 161 water 149 adenylate 142 Clin 129 phosphate 116 cAMP 114 Insulin 110 serine 104 nitric oxide 95 NAD 92 sodium 78 Resveratrol 75 MTT 74 ethanol 74 NAD 74 MDA 72 ADP 72 palmitic acid 70 ADP 65 ADP 65 CPT 63 CPT 63 tyrosine 62 GSH 61 GSH 61 hydrogen 58 methionine 57 galactose 53 CoA 53 palmitic acid 48 glutamine 47 cysteine 47 nitrogen 46 leucine 46 acetate 45 MEK 44 arginine 43 N-acetylcysteine 42 Cardiol 40 Rapamycin 38 urea 38 nicotinamide 37 STZ 37 lysine 34 cGMP 33 glycerol 33 Berberine 33 alanine 33 Guo 32 NADH 32 salt 32 Oil Red O 31 glutamate 31 Oil Red O 31 H2O2 30 THP 29 THP 29 pentose 28 pentose 28 pentose 28 pentose 28 creatinine 27 TSC 25 Curcumin 25 NADPH 24 NADPH 24 sulfate 24 acetyl-CoA 24 more...

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