Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.27 (AMPK)
6,299 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
AMPK 6226
mTOR 1249
insulin 1082
Mol 637
ATP 582
AMP-activated protein kinase 511
PI3K 410
AKT 401
LKB1 382
PGC 329
adiponectin 309
Sep 305
AMP 304
LC3 298
MAPK 290
SIRT1 290
p53 267
ROS 247
AICAR 235
TNF 233
ACC 214
ULK1 206
caspase-3 205
ERK 203
p62 197
p38 197
JNK 173
endoplasmic reticulum 165
GLUT4 162
leptin 159
Bcl-2 157
IL-6 157
Beclin-1 150
acetyl-CoA carboxylase 149
peroxisome proliferator-activated receptor 138
PPAR 135
Nrf2 135
ERK1 122
cytokine 122
IRS-1 106
more...
Disease
cancer 1080
obesity 644
tumor 615
diabetes 593
type 2 diabetes 375
fatty liver 204
breast cancer 173
hyperglycemia 166
tumor growth 162
hepatocellular carcinoma 147
ischemia 141
metabolic syndrome 123
tumorigenesis 123
Alzheimer's disease 111
atherosclerosis 105
FAS 97
hypertension 83
lung cancer 82
prostate cancer 82
cardiovascular disease 81
tumor progression 74
colorectal cancer 74
hyperlipidemia 72
heart failure 71
dyslipidemia 68
glucose intolerance 66
stroke 63
GSH 61
myocardial ischemia 60
alcoholic fatty liver 59
myocardial infarction 58
carcinogenesis 58
carcinoma 55
Parkinson's disease 54
ATM 53
adenocarcinoma 52
MCF 45
pancreatic cancer 45
non-small cell lung cancer 43
tuberous sclerosis 43
more...
Symptom
starvation 139
fatigue 29
pain 25
collapse 21
functional recovery 21
overweight 20
exhaustion 18
cachexia 14
weakness 10
hunger 10
anesthesia 9
memory loss 8
diarrhea 7
hypothermia 6
respiratory distress 6
hypercapnia 4
seizures 4
anorexia 4
hyperoxia 3
thinning 3
low back pain 3
acute pain 2
hepatomegaly 2
bradykinesia 2
angina 2
insomnia 2
chills 2
Neuropathic pain 2
ataxia 2
tremor 2
pallor 2
back pain 2
menopausal symptoms 2
cough 2
vomiting 1
stigma 1
abdominal pain 1
Anoxia 1
stomach cramps 1
syncope 1
more...
Drug
ROS 247
NADH 32
Parkin 28
Parkin 28
lysine 27
Monit 21
Cardiovasc 17
RFP 13
MAP 13
caffeine 12
Ethanol 12
Liraglutide 11
Ginseng 11
Rosiglitazone 10
Glucagon 10
ascorbate 10
Dermatol 9
CSF 8
EE2 7
Sorafenib 7
vitamin E 7
3-Methyladenine 7
ALA 6
citric acid 6
Angiotensin II 5
Ara-A 5
TAK 5
Glycyrrhiza 5
Arsenic trioxide 5
Simvastatin 5
Itraconazole 5
Adenosine Monophosphate 4
EPA 4
Ezetimibe 4
Emodin 4
Emodin 4
Bifidobacterium 4
Troglitazone 4
Acadesine 4
Docetaxel 4
more...
Enzyme
AMPK 6299
AMP-activated protein kinase 6228
AMPK 6226
protein kinase 697
mitogen-activated protein kinase 570
ERK 304
focal adhesion kinase 199
acetyl-CoA carboxylase 155
superoxide dismutase 142
caspase-3 140
CPT 94
protein kinase C 86
alanine aminotransferase 82
PARP 79
catalase 74
aspartate aminotransferase 71
proteasome 67
CPT 63
complex I 63
CPT 63
MEK 57
phosphoenolpyruvate carboxykinase 56
GSK 53
ATPase 52
citrate synthase 48
luciferase 47
TOR 47
calcineurin 46
lactate dehydrogenase 46
CaMKII 44
hormone-sensitive lipase 44
phosphatidylinositol 3-kinase 38
AST 37
PDK1 35
glutathione peroxidase 32
NADPH oxidase 31
NADPH oxidase 31
IKK 30
AMP-activated kinase 30
caspase-1 28
more...
Compound
glucose 1397
oxygen 588
ATP 582
AMP 373
Dec 355
DNA 315
Metformin 284
Metformin 284
AICAR 249
AICAR 237
TNF 233
calcium 218
threonine 161
water 149
adenylate 142
Clin 129
phosphate 116
cAMP 114
Insulin 110
serine 104
nitric oxide 95
NAD 92
sodium 78
Resveratrol 75
ethanol 74
NAD 74
MTT 74
MDA 72
ADP 72
palmitic acid 70
ADP 65
ADP 65
CPT 63
CPT 63
tyrosine 62
GSH 61
GSH 61
hydrogen 58
methionine 57
CoA 53
more...