Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.11.27 (
AMPK
)
6,299
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
AMPK
6226
mTOR
1249
insulin
1082
Mol
637
ATP
582
AMP-activated protein kinase
511
PI3K
410
AKT
401
LKB1
382
PGC
329
adiponectin
309
Sep
305
AMP
304
LC3
298
MAPK
290
SIRT1
290
p53
267
ROS
247
AICAR
235
TNF
233
more...
Disease
cancer
1080
obesity
644
tumor
615
diabetes
593
type 2 diabetes
375
fatty liver
204
breast cancer
173
hyperglycemia
166
tumor growth
162
hepatocellular carcinoma
147
ischemia
141
tumorigenesis
123
metabolic syndrome
123
Alzheimer's disease
111
atherosclerosis
105
FAS
97
hypertension
83
prostate cancer
82
lung cancer
82
cardiovascular disease
81
more...
Symptom
starvation
139
fatigue
29
pain
25
collapse
21
functional recovery
21
overweight
20
exhaustion
18
cachexia
14
weakness
10
hunger
10
anesthesia
9
memory loss
8
diarrhea
7
hypothermia
6
respiratory distress
6
seizures
4
hypercapnia
4
anorexia
4
low back pain
3
hyperoxia
3
more...
Drug
ROS
247
NADH
32
Parkin
28
Parkin
28
lysine
27
Monit
21
Cardiovasc
17
MAP
13
RFP
13
caffeine
12
Ethanol
12
Ginseng
11
Liraglutide
11
ascorbate
10
Glucagon
10
Rosiglitazone
10
Dermatol
9
CSF
8
3-Methyladenine
7
vitamin E
7
more...
Enzyme
AMPK
6299
AMP-activated protein kinase
6228
AMPK
6226
protein kinase
697
mitogen-activated protein kinase
570
ERK
304
focal adhesion kinase
199
acetyl-CoA carboxylase
155
superoxide dismutase
142
caspase-3
140
CPT
94
protein kinase C
86
alanine aminotransferase
82
PARP
79
catalase
74
aspartate aminotransferase
71
proteasome
67
complex I
63
CPT
63
CPT
63
more...
Compound
glucose
1397
oxygen
588
ATP
582
AMP
373
Dec
355
DNA
315
Metformin
284
Metformin
284
AICAR
249
AICAR
237
TNF
233
calcium
218
threonine
161
water
149
adenylate
142
Clin
129
phosphate
116
cAMP
114
Insulin
110
serine
104
more...