Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.26 (GSK)
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Human Gene/Protein
CDC like kinase 2 12.2
PCDHB2 12.2
ACSS2 protein 12.2
STK31 12.2
KLC2 protein 12.2
TDRD8 12.2
TTK 12.2
GSK 12.2
Makorin-2 11.2
Zinc finger protein 281 11.2
NUP58 11.2
Inositol polyphosphate-5-phosphatase F 11.2
sperm autoantigenic protein 17 11.2
tripartite motif-containing 29 11.2
RPS6KC1 11.2
Microtubule-actin crosslinking factor 1 11.2
Nucleolar protein 14 11.2
Glycogen synthase kinase 3 beta 11.0
glycogen synthase kinase-3 beta 10.9
Glycogen synthase 10.8
protein kinase TTK 10.7
SOLH protein 10.6
TDRD4 10.6
TRIM29 protein 10.6
QSER1 10.6
HIST1H2BM 10.6
CDC42EP1 10.6
HSH2D 10.6
FBXO16 10.6
kinesin light chain 2 10.6
gamma-taxilin 10.6
Protocadherin 9 10.6
copine 6 10.6
serine/threonine kinase 31 10.6
FRAT1 10.5
tetraspanin 12 10.2
CKI-epsilon 10.2
Fwd2 10.2
FBXO39 10.2
INPP1 10.2
C3orf1 10.2
fibronectin precursor 10.2
SH3GL1 10.2
TTBK2 10.2
septin 1 10.2
glycogen synthase kinase 3 10.1
H2A.3 9.9
SPSB3 9.9
Transgelin 2 9.9
LRP3 9.9
ubiquitin specific peptidase 16 9.9
ubiquitously transcribed tetratricopeptide repeat, X chromosome 9.9
ZNF124 9.9
HMGCLL1 9.9
frequently rearranged in advanced T-cell lymphomas 9.9
MyoD family inhibitor 9.9
PTP-U2 9.9
prune protein 9.9
TDRD12 9.9
TPK1 9.8
PP-1G 9.7
TIAF1 9.6
SGOL1 9.6
FKBP9 9.6
sprouty-related, EVH1 domain containing 1 9.6
H2-relaxin 9.6
MITF-C 9.6
GNG3 9.6
CDH22 9.6
Serine/threonine kinase 11 9.6
FRAT2 9.5
glycogen synthase kinase 3 beta 9.5
centromere protein H 9.4
SLFN5 9.4
TCF-3 9.4
protein kinase C, epsilon 9.4
NKAPL 9.4
EXOC5 9.4
Programmed cell death 6 9.4
CLK3 9.3
more...
Disease
Deficiency of protein phosphatase 12.2
Conjunctival intraepithelial neoplasia 9.9
Myeloid Leukemia 8.6
floppy baby syndrome 8.5
Radiation Syndrome 7.9
Aortic valve calcification 7.5
Tauopathies 7.3
DSH 7.1
Malignant pheochromocytoma 7.0
Direct infection 6.9
DMAT 6.8
Diabetic gastroparesis 6.7
NEK1 6.7
Diabetic encephalopathy 6.5
melanoderma 6.5
Hepatic cysts 6.5
EPM2B 6.5
IPV 6.4
Retinal damage 6.4
ADA-SCID 6.3
CNS demyelinating disease 6.2
recurrent colon cancer 6.1
Turcot syndrome 6.1
CPAF 6.1
heritable connective tissue disorder 6.0
EMT 6.0
PARK8 5.9
SCA17 5.9
Peritoneal fibrosis 5.8
environmental carcinogenesis 5.8
DA3 5.8
AD2 5.8
Transient cerebral ischemia 5.7
Postoperative cognitive dysfunction 5.7
gum disease 5.7
vascular ischemia 5.6
Vascular dementia 5.6
Leydig cell hyperplasia 5.6
Epidermolytic hyperkeratosis 5.6
Viral myocarditis 5.6
alcoholic ketoacidosis 5.6
PAPA 5.5
PARK6 5.5
OBX 5.5
alcoholic cardiomyopathy 5.4
Bone sarcomas 5.4
Burkitt-like lymphoma 5.4
AT/RT 5.4
Alzheimer's disease 5.3
bipolar disorder 5.3
AML progression 5.3
Fibrodysplasia ossificans progressiva 5.3
diabetic ulcer 5.3
viral carcinogenesis 5.2
ALS2 5.2
diabetic cardiomyopathy 5.2
RTS 5.2
Thorn 5.2
Hepatocarcinogenesis 5.2
Photosensitized 5.2
cancer angiogenesis 5.1
memory impairment 5.1
Primary liver cancer 5.0
MSD 5.0
avitaminosis 5.0
Hemorrhagic cystitis 4.9
MDM 4.9
AGS 4.9
PSN 4.9
erythroplakia 4.8
pediatric brain tumor 4.8
radioulnar synostosis 4.8
cognitive disorder 4.8
Phototoxicity 4.8
FHA 4.7
INS 4.7
OCM 4.7
APC 4.7
Sendai virus infection 4.6
Medulloblastoma 4.6
more...
Symptom
Injection site pain 7.9
Excitable 5.8
memory loss 4.6
impaired motor coordination 4.6
Scratch 4.6
postnasal drip 4.2
despair 3.5
Involuntary Movement 3.5
functional recovery 3.3
neurological disability 3.3
adenitis 3.1
acute stress 2.8
skin damage 2.6
incoordination 2.4
polyuria 2.2
chorea 2.2
muscle rigidity 2.1
abnormal gait 2.1
nasal congestion 2.0
decreased appetite 2.0
bradykinesia 2.0
hot flushes 1.9
Mills 1.9
cachexia 1.7
Neuropathic pain 1.7
menopausal symptoms 1.5
starvation 1.5
apathy 1.2
collapse 1.2
hypothermia 0.9
hyperoxia 0.8
dry eye 0.8
agitation 0.6
seizures 0.5
cerebellar ataxia 0.4
acute pain 0.2
ataxia 0.2
wheezing -0.0
respiratory distress -0.1
insomnia -0.2
hunger -0.3
paresis -0.3
hypotonia -0.3
nausea -0.3
tremor -0.4
sleepiness -0.4
myalgia -0.5
exhaustion -0.5
arthralgia -0.6
pain -0.6
anesthesia -0.6
diarrhea -0.8
dystonia -0.8
fatigue -0.9
low back pain -1.1
Ill -1.3
thinning -1.3
erythema -1.5
anorexia -1.6
abdominal pain -1.7
vomiting -1.8
weakness -2.0
angina -2.2
cough -2.3
dyspnea -2.6
analgesia -2.6
headache -3.6
Drug
Tolevamer potassium sodium 12.2
Rebimastat 12.2
Apilimod mesylate 12.2
Lecozotan hydrochloride 12.2
Denibulin hydrochloride 12.2
Lapuleucel-T 12.2
Ispinesib mesylate 11.6
Esomeprazole sodium 11.2
Dronedarone hydrochloride 11.2
Velafermin 11.2
Fenspiride hydrochloride 11.2
Telavancin hydrochloride 10.9
Denufosol tetrasodium 10.6
Belotecan hydrochloride 10.6
Icatibant acetate 10.6
Vernakalant hydrochloride 10.3
Pitavastatin calcium 10.3
Canfosfamide hydrochloride 10.2
Alsterpaullone 10.2
Succinobucol 10.2
Lasofoxifene tartrate 10.2
Peginterferon alfa-2b 10.0
Peginterferon alfa-2b 10.0
Pratosartan 9.9
Enzastaurin hydrochloride 9.9
Montirelin 9.9
Hymenialdisine 9.9
Pemetrexed disodium 9.7
Soblidotin 9.6
Lexatumumab 9.6
Lumiliximab 9.6
Becatecarin 9.6
Aliskiren fumarate 9.6
Sugammadex sodium 9.4
Talabostat 9.4
Visilizumab 9.4
Alvocidib 9.4
Apaziquone 9.4
Duloxetine hydrochloride 9.3
Hydrocodone bitartrate 9.2
Talaporfin sodium 9.2
Pazopanib hydrochloride 9.2
Amdoxovir 9.2
Escitalopram oxalate 9.1
Oncophage 9.0
Desvenlafaxine succinate 9.0
Alovudine 9.0
Focalin 9.0
Solifenacin succinate 9.0
Aquavan 8.9
Mapatumumab 8.9
Atomoxetine hydrochloride 8.9
Darifenacin hydrobromide 8.9
Metreleptin 8.8
Cinacalcet hydrochloride 8.8
Fluticasone furoate 8.7
Asoprisnil 8.6
Rosuvastatin calcium 8.5
Fingolimod hydrochloride 8.5
Lestaurtinib 8.5
Lutropin alfa 8.5
Dapoxetine hydrochloride 8.5
Zotarolimus 8.5
Atazanavir sulfate 8.4
Indisulam 8.4
Nasonex 8.4
Bazedoxifene acetate 8.3
Sevelamer carbonate 8.3
Chantix 8.3
Pegasys 8.2
Lixivaptan 8.2
Viramidine 8.2
Valcyte 8.2
Agalsidase alfa 8.2
Insulin glulisine 8.2
Flixotide 8.1
Indiplon 8.0
Bextra 8.0
Tafluprost 8.0
Tykerb 8.0
more...
Enzyme
GSK 12.2
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase 9.6
thiamine pyrophosphokinase 8.4
CLK1 7.2
type 1 protein phosphatase 7.1
phosphatidylinositol-4,5-bisphosphate 3-kinase 7.1
isochorismatase 6.9
protein kinase 6.8
phosphatidylinositol 3-kinase 6.8
histone demethylase 6.6
N-acetylglucosaminyltransferase III 6.6
protein phosphatase 2A 6.5
inositol 3-kinase 6.3
enzyme X 6.3
PDK1 6.3
phosphoinositide 3-kinase 6.2
CTD kinase 6.1
protein L-isoaspartyl methyltransferase 5.9
cdc2 5.8
O-GlcNAc transferase 5.8
MPP 5.7
STK2 5.7
calcineurin 5.5
polyphosphatase 5.4
proteinase-3 5.4
Omi/HtrA2 5.4
AMP-activated kinase 5.3
caspase-3 5.3
AMPK 5.3
caspase-9 5.3
demethylase 5.3
glycyl-tRNA synthetase 5.2
sulfiredoxin 5.2
TGT 5.2
tRNase Z 5.2
MEK 5.2
prolyl endopeptidase 5.1
AMP-activated protein kinase 5.0
CaMKII 5.0
insulin-degrading enzyme 5.0
phosphorylase kinase 5.0
mitogen-activated protein kinase 5.0
AMPK 4.9
caspase-2 4.9
fatty-acid synthase 4.9
caspase-2 4.9
inositol phosphatase 4.8
focal adhesion kinase 4.7
caspase-7 4.7
caspase-7 4.7
IKK 4.6
polo-like kinase 1 4.6
glucose-6-phosphatase 4.6
NQO2 4.6
CFI 4.6
PKG 4.5
endoproteinase Glu-C 4.5
TOR 4.5
phosphocholine cytidylyltransferase 4.4
PARP 4.4
beta-secretase 4.4
trehalase 4.4
protein kinase C 4.3
phosphoenolpyruvate carboxykinase 4.3
PHT 4.2
ECH 4.2
MAP 4.1
kinesin 4.1
caspase-8 4.0
leucyl-tRNA synthetase 4.0
APC 4.0
LIS 3.9
proteasome 3.9
MEKK1 3.9
15-hydroxyprostaglandin dehydrogenase 3.9
ERK 3.9
glucokinase 3.9
acetyl-CoA carboxylase 3.9
GMT 3.8
separase 3.8
more...
Compound
Glycogen synthase 10.9
Arnebin 10.6
Fungichromin 10.2
Telocinobufagin 10.2
Berberine iodide 10.2
2,2',4,4',5,5'-Hexachlorobiphenyl 9.9
Justicidin A 9.9
Bakkenolide A 9.9
Aldophosphamide 9.6
Fungichromin 9.2
Indirubin 9.2
Lithium chloride 9.2
Resibufogenin 9.0
2-methylbenzamide 9.0
Convallatoxin 9.0
3,5-dibromopyridine 9.0
Poncirin 8.9
Plantamajoside 8.9
Triptonide 8.7
Physalin B 8.7
Chebulagic acid 8.6
Chebulagic acid 8.6
Resolvin D2 8.6
Hymenialdisine 8.6
Tricetin 8.5
Cyanidin 3-O-beta-D-glucoside 8.5
Obacunone 8.4
8-methylquinoline 8.3
Totarol 8.3
Imexon 8.2
Dictamnine 8.1
L-Alanosine 8.0
Dehydrocostus lactone 7.9
Xanthatin 7.9
Trimethyltin chloride 7.9
Chebulinic acid 7.9
Pinosylvin 7.8
Pinosylvin 7.8
Butylidenephthalide 7.7
Farrerol 7.6
dihexyl phthalate 7.6
Xanthatin 7.6
Ethyl lactate 7.6
Sulfuretin 7.6
Daphnetin 7.6
Harpagoside 7.6
Tautomycin 7.5
3,4-dimethoxybenzoic acid 7.4
Falcarindiol 7.4
3-OMG 7.4
Isoalantolactone 7.3
Berberine chloride 7.3
Rutaecarpine 7.2
FPL64176 7.2
Rutaecarpine 7.2
DX-52-1 7.2
Acacetin 7.2
Fangchinoline 7.2
Betnesol 7.2
Cinobufagin 7.2
octacosanoic acid 7.2
Lithium 7.1
Etoricoxib 7.1
Wortmannin 7.1
Salvianolic acid A 7.1
imidazo[1,5-a]pyridine 7.0
1,3-benzoxazole 7.0
Tuberin 7.0
27-Hydroxycholesterol 7.0
Glycogen 7.0
Humulene 6.9
Asiatic acid 6.9
1,4-dithiane 6.9
Deoxypodophyllotoxin 6.9
Brusatol 6.9
Emtricitabine 6.9
Azoxymethane 6.8
Blue Tetrazolium 6.8
Nitroxoline 6.8
9(10H)-anthracenone 6.8
more...