Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.26 (GSK)
6,788 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
GSK 6068
catenin 944
Mol 743
insulin 538
AKT 524
beta-catenin 498
PI3K 486
Glycogen synthase 478
Sep 434
caspase-3 378
protein kinase B 285
Bcl-2 267
mTOR 260
phosphatidylinositol 3-kinase 256
tau protein 243
cyclin D1 241
glycogen synthase kinase 3 231
ERK 214
ERK1 210
MAPK 206
ATP 195
p38 172
E-cadherin 172
p53 168
threonine 163
TNF 162
TTK 155
glycogen synthase 150
cytokine 144
amyloid precursor protein 143
serine/threonine kinase 141
phosphatase 141
JNK 132
GSK3 132
PKB 124
IRS-1 121
PTEN 120
Axin 112
brain-derived neurotrophic factor 106
axonal 104
collagen 96
phosphoinositide 3-kinase 95
MEK 94
proteasome 94
IL-6 91
TCF 90
insulin receptor 88
c-Myc 88
PKC 87
Nrf2 85
CREB 85
cyclin 83
tumor necrosis factor 83
p65 83
histone 82
c-myc 82
endoplasmic reticulum 81
extracellular signal-regulated kinase 81
cytochrome c 80
glycogen synthase kinase-3 beta 78
lipopolysaccharide 78
caspase-9 77
PI3 74
p21 73
glycogen synthase kinase 3 beta 72
phosphorylating 70
tyrosine kinase 70
adenomatous polyposis coli 70
osteogenic 68
GSH 67
superoxide dismutase 66
ROS 64
PKA 63
c-Jun 62
lymphoid 60
serine/threonine protein kinase 60
N-cadherin 59
calcineurin 58
PARP 57
erythroid 56
more...
Disease
cancer 1004
Alzheimer's disease 961
tumor 643
diabetes 324
ischemia 245
tumorigenesis 199
breast cancer 170
hepatocellular carcinoma 145
cognitive impairment 135
Parkinson's disease 128
carcinogenesis 126
bipolar disorder 123
neuroblastoma 122
tumor growth 121
depression 118
type 2 diabetes 117
colorectal cancer 109
colon cancer 100
dementia 96
schizophrenia 95
stroke 94
carcinoma 93
prostate cancer 88
tumor progression 85
obesity 72
GSH 67
lung cancer 65
cerebral ischemia 63
MCF 61
leukemia 60
glioma 59
myocardial infarction 56
melanoma 56
APC 55
adenocarcinoma 55
gastric cancer 54
pancreatic cancer 52
memory impairment 52
hyperglycemia 48
heart failure 47
myocardial ischemia 45
EMT 39
osteosarcoma 38
osteoporosis 37
HIV 37
metastases 37
glioblastoma 36
squamous cell carcinoma 34
retinoblastoma 33
lymphoma 32
diabetic nephropathy 32
acute myeloid leukemia 31
ovarian cancer 30
hypertension 29
asthma 29
non-small cell lung cancer 28
amyotrophic lateral sclerosis 28
hepatitis B 27
sepsis 27
sepsis 27
chronic obstructive pulmonary disease 26
malaria 26
liver cancer 26
plaque 25
pertussis 24
cardiovascular disease 24
Huntington's disease 24
atherosclerosis 23
hyperinsulinemia 23
B-cell lymphoma 22
cervical cancer 21
epilepsy 21
aggressiveness 20
Blocking 20
mania 19
pheochromocytoma 19
renal cell carcinoma 19
psychosis 19
fatty liver 19
SAR 18
more...
Symptom
pain 36
functional recovery 29
seizures 24
memory loss 19
starvation 15
anesthesia 15
collapse 14
diarrhea 7
acute stress 7
hypothermia 7
fatigue 6
nausea 4
ataxia 4
agitation 4
respiratory distress 4
cachexia 4
despair 4
tremor 3
polyuria 3
exhaustion 2
insomnia 2
abdominal pain 2
chorea 2
apathy 2
Scratch 2
skin damage 2
neurological disability 2
hyperoxia 2
weakness 2
incoordination 2
sleepiness 2
vomiting 2
bradykinesia 2
wheezing 1
decreased appetite 1
hot flushes 1
hypotonia 1
acute pain 1
muscle rigidity 1
adenitis 1
anorexia 1
nasal congestion 1
Mills 1
hunger 1
erythema 1
impaired motor coordination 1
menopausal symptoms 1
Injection site pain 1
cough 1
low back pain 1
abnormal gait 1
dry eye 1
angina 1
Excitable 1
dyspnea 1
analgesia 1
dystonia 1
arthralgia 1
Involuntary Movement 1
paresis 1
postnasal drip 1
headache 1
thinning 1
Neuropathic pain 1
myalgia 1
cerebellar ataxia 1
Ill 1
Drug
ROS 64
lysine 51
MAP 33
Cardiovasc 19
Monit 15
IL-2 13
Dermatol 13
Sorafenib 11
Ethanol 10
ICI 9
CSF 9
Bortezomib 9
CTX 8
caffeine 8
Ezetimibe 8
Donepezil 7
Everolimus 7
Denosumab 6
NVP 6
PCP 6
Pemetrexed disodium 6
Pegasys 6
Sunitinib malate 6
Tocilizumab 6
Gefitinib 6
vitamin E 6
EE2 6
Dasatinib 6
Portal 6
Vorinostat 6
Gleevec 6
Gel 6
CTX 6
Glycyrrhiza 6
CIA 6
Taxol 6
Bevacizumab 6
Lenalidomide 6
CTX 6
Peginterferon alfa-2b 5
Cetuximab 5
Parkin 5
Entecavir 5
Entecavir 5
Darbepoetin alfa 5
Zoledronic acid 5
Angiotensin II 5
Fondaparinux 5
Peginterferon alfa-2b 5
GEO 5
Adalimumab 5
Parkin 5
Epoetin 5
Retinoic acid 5
Activin 5
Rosuvastatin calcium 5
ADR 5
G-CSF 5
Imatinib 5
Asthma 5
Simvastatin 5
TTC 5
Pimecrolimus 5
Zoledronic acid 4
Teriparatide 4
NADH 4
Aliskiren fumarate 4
Salbutamol 4
Heme 4
Liraglutide 4
Pregabalin 4
Escitalopram oxalate 4
Growth hormone 4
Emodin 4
Duloxetine hydrochloride 4
Fulvestrant 4
IFN-gamma 4
ABC 4
PMPA 4
Dutasteride 4
more...
Enzyme
GSK 6788
protein kinase 1908
mitogen-activated protein kinase 642
caspase-3 305
ERK 304
phosphatidylinositol 3-kinase 256
focal adhesion kinase 247
protein kinase C 208
calcineurin 169
MEK 138
cdc2 100
superoxide dismutase 98
luciferase 97
phosphoinositide 3-kinase 95
proteasome 94
AMP-activated protein kinase 91
AMPK 81
caspase-9 63
PARP 62
protein phosphatase 2A 57
APC 55
AMPK 53
lactate dehydrogenase 52
catalase 49
demethylase 45
acetylcholinesterase 44
alkaline phosphatase 44
ACS 38
PDK1 37
glutathione peroxidase 30
alanine aminotransferase 29
MAP 28
creatine kinase 28
CaMKII 28
phosphodiesterase 27
IKK 26
ATPase 25
tyrosine hydroxylase 25
caspase-8 24
aspartate aminotransferase 24
glutathione S-transferase 21
MPP 21
histone demethylase 20
kinesin 19
phosphoenolpyruvate carboxykinase 19
peroxidase 18
NO synthase 16
glucose-6-phosphatase 16
cholinesterase 15
trypsin 15
NQO1 15
phospholipase C 14
adenylate cyclase 14
phosphoenolpyruvate carboxykinase 12
MMP 12
phosphoenolpyruvate carboxykinase 12
NADPH oxidase 12
reverse transcriptase 12
heme oxygenase 12
PKG 12
P-glycoprotein 11
hexokinase 11
tyrosinase 11
phosphorylase 10
NADPH oxidase 10
acetyl-CoA carboxylase 9
phospholipase A2 9
RNA polymerase 9
AST 9
thrombin 9
glucokinase 9
complex I 9
aldehyde dehydrogenase 8
guanylate cyclase 8
choline acetyltransferase 8
polo-like kinase 1 8
thiamine pyrophosphokinase 7
PDE 7
aldehyde dehydrogenase 7
aldehyde dehydrogenase 7
more...
Compound
glucose 489
Glycogen synthase 478
Dec 443
serine 364
DNA 309
threonine 299
oxygen 285
tyrosine 259
ATP 195
water 186
calcium 175
TNF 162
Lithium 138
cAMP 122
Insulin 105
glutamate 98
sodium 97
phosphate 95
Clin 94
MTT 93
MEK 90
MDA 77
nitric oxide 67
GSH 67
GSH 67
alanine 66
lysine 65
hydrogen 64
Glycogen 63
AMP 53
zinc 47
sulfate 46
Cardiol 45
ethanol 44
proline 40
bromide 39
ACS 38
ACS 38
retinoic acid 38
arginine 37
potassium 36
iodine 36
acetate 35
Wortmannin 34
STZ 34
Lithium chloride 33
H2O2 32
leucine 31
nitrogen 30
cysteine 30
MAP 28
Phosphatidylinositol 27
salt 27
COS 26
Curcumin 25
Asp 25
Serine 24
NMDA 24
dUTP 23
galactose 22
urea 22
MPP 21
MPP 21
MPTP 21
Vimentin 20
5-HT 20
pyridine 19
cGMP 19
ADP 19
methionine 19
ADP 19
ADP 19
Valproic acid 18
PGE 18
Neuronal 18
SDS 17
Melatonin 17
Rapamycin 17
Resveratrol 16
Indirubin 15
more...