Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.26 (GSK)
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Human Gene/Protein
TDRD8 12.2
PCDHB2 12.2
TTK 12.2
STK31 12.2
ACSS2 protein 12.2
CDC like kinase 2 12.2
KLC2 protein 12.2
GSK 12.2
Zinc finger protein 281 11.2
Microtubule-actin crosslinking factor 1 11.2
NUP58 11.2
RPS6KC1 11.2
Inositol polyphosphate-5-phosphatase F 11.2
Makorin-2 11.2
tripartite motif-containing 29 11.2
sperm autoantigenic protein 17 11.2
Nucleolar protein 14 11.2
Glycogen synthase kinase 3 beta 11.0
glycogen synthase kinase-3 beta 10.9
Glycogen synthase 10.8
protein kinase TTK 10.7
gamma-taxilin 10.6
HSH2D 10.6
Protocadherin 9 10.6
CDC42EP1 10.6
copine 6 10.6
SOLH protein 10.6
HIST1H2BM 10.6
TRIM29 protein 10.6
FBXO16 10.6
TDRD4 10.6
kinesin light chain 2 10.6
serine/threonine kinase 31 10.6
QSER1 10.6
FRAT1 10.5
Fwd2 10.2
INPP1 10.2
TTBK2 10.2
FBXO39 10.2
C3orf1 10.2
more...
Disease
Deficiency of protein phosphatase 12.2
Conjunctival intraepithelial neoplasia 9.9
Myeloid Leukemia 8.6
floppy baby syndrome 8.5
Radiation Syndrome 7.9
Aortic valve calcification 7.5
Tauopathies 7.3
DSH 7.1
Malignant pheochromocytoma 7.0
Direct infection 6.9
DMAT 6.8
Diabetic gastroparesis 6.7
NEK1 6.7
Diabetic encephalopathy 6.5
melanoderma 6.5
Hepatic cysts 6.5
EPM2B 6.5
IPV 6.4
Retinal damage 6.4
ADA-SCID 6.3
CNS demyelinating disease 6.2
recurrent colon cancer 6.1
Turcot syndrome 6.1
CPAF 6.1
heritable connective tissue disorder 6.0
EMT 6.0
PARK8 5.9
SCA17 5.9
Peritoneal fibrosis 5.8
environmental carcinogenesis 5.8
DA3 5.8
AD2 5.8
Transient cerebral ischemia 5.7
Postoperative cognitive dysfunction 5.7
gum disease 5.7
vascular ischemia 5.6
Vascular dementia 5.6
Leydig cell hyperplasia 5.6
alcoholic ketoacidosis 5.6
Viral myocarditis 5.6
more...
Symptom
Injection site pain 7.9
Excitable 5.8
memory loss 4.6
impaired motor coordination 4.6
Scratch 4.6
postnasal drip 4.2
despair 3.5
Involuntary Movement 3.5
functional recovery 3.3
neurological disability 3.3
adenitis 3.1
acute stress 2.8
skin damage 2.6
incoordination 2.4
polyuria 2.2
chorea 2.2
muscle rigidity 2.1
abnormal gait 2.1
nasal congestion 2.0
decreased appetite 2.0
bradykinesia 2.0
hot flushes 1.9
Mills 1.9
cachexia 1.7
Neuropathic pain 1.7
menopausal symptoms 1.5
starvation 1.5
apathy 1.2
collapse 1.2
hypothermia 0.9
hyperoxia 0.8
dry eye 0.8
agitation 0.6
seizures 0.5
cerebellar ataxia 0.4
acute pain 0.2
ataxia 0.2
wheezing -0.0
respiratory distress -0.1
insomnia -0.2
more...
Drug
Lecozotan hydrochloride 12.2
Denibulin hydrochloride 12.2
Rebimastat 12.2
Lapuleucel-T 12.2
Tolevamer potassium sodium 12.2
Apilimod mesylate 12.2
Ispinesib mesylate 11.6
Velafermin 11.2
Dronedarone hydrochloride 11.2
Fenspiride hydrochloride 11.2
Esomeprazole sodium 11.2
Telavancin hydrochloride 10.9
Denufosol tetrasodium 10.6
Icatibant acetate 10.6
Belotecan hydrochloride 10.6
Vernakalant hydrochloride 10.3
Pitavastatin calcium 10.3
Lasofoxifene tartrate 10.2
Canfosfamide hydrochloride 10.2
Succinobucol 10.2
Alsterpaullone 10.2
Peginterferon alfa-2b 10.0
Peginterferon alfa-2b 10.0
Pratosartan 9.9
Hymenialdisine 9.9
Montirelin 9.9
Enzastaurin hydrochloride 9.9
Pemetrexed disodium 9.7
Soblidotin 9.6
Becatecarin 9.6
Lexatumumab 9.6
Lumiliximab 9.6
Aliskiren fumarate 9.6
Apaziquone 9.4
Visilizumab 9.4
Alvocidib 9.4
Talabostat 9.4
Sugammadex sodium 9.4
Duloxetine hydrochloride 9.3
Pazopanib hydrochloride 9.2
more...
Enzyme
GSK 12.2
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase 9.6
thiamine pyrophosphokinase 8.4
CLK1 7.2
type 1 protein phosphatase 7.1
phosphatidylinositol-4,5-bisphosphate 3-kinase 7.1
isochorismatase 6.9
protein kinase 6.8
phosphatidylinositol 3-kinase 6.8
histone demethylase 6.6
N-acetylglucosaminyltransferase III 6.6
protein phosphatase 2A 6.5
inositol 3-kinase 6.3
enzyme X 6.3
PDK1 6.3
phosphoinositide 3-kinase 6.2
CTD kinase 6.1
protein L-isoaspartyl methyltransferase 5.9
cdc2 5.8
O-GlcNAc transferase 5.8
MPP 5.7
STK2 5.7
calcineurin 5.5
proteinase-3 5.4
polyphosphatase 5.4
Omi/HtrA2 5.4
AMP-activated kinase 5.3
caspase-3 5.3
AMPK 5.3
caspase-9 5.3
demethylase 5.3
glycyl-tRNA synthetase 5.2
sulfiredoxin 5.2
TGT 5.2
tRNase Z 5.2
MEK 5.2
prolyl endopeptidase 5.1
AMP-activated protein kinase 5.0
CaMKII 5.0
insulin-degrading enzyme 5.0
more...
Compound
Glycogen synthase 10.9
Arnebin 10.6
Fungichromin 10.2
Berberine iodide 10.2
Telocinobufagin 10.2
2,2',4,4',5,5'-Hexachlorobiphenyl 9.9
Justicidin A 9.9
Bakkenolide A 9.9
Aldophosphamide 9.6
Fungichromin 9.2
Indirubin 9.2
Lithium chloride 9.2
Resibufogenin 9.0
Convallatoxin 9.0
2-methylbenzamide 9.0
3,5-dibromopyridine 9.0
Poncirin 8.9
Plantamajoside 8.9
Physalin B 8.7
Triptonide 8.7
Chebulagic acid 8.6
Chebulagic acid 8.6
Resolvin D2 8.6
Hymenialdisine 8.6
Tricetin 8.5
Cyanidin 3-O-beta-D-glucoside 8.5
Obacunone 8.4
8-methylquinoline 8.3
Totarol 8.3
Imexon 8.2
Dictamnine 8.1
L-Alanosine 8.0
Dehydrocostus lactone 7.9
Xanthatin 7.9
Trimethyltin chloride 7.9
Chebulinic acid 7.9
Pinosylvin 7.8
Pinosylvin 7.8
Butylidenephthalide 7.7
Farrerol 7.6
more...