Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.11.26 (
GSK
)
6,788
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
GSK
6068
catenin
944
Mol
743
insulin
538
AKT
524
beta-catenin
498
PI3K
486
Glycogen synthase
478
Sep
434
caspase-3
378
protein kinase B
285
Bcl-2
267
mTOR
260
phosphatidylinositol 3-kinase
256
tau protein
243
cyclin D1
241
glycogen synthase kinase 3
231
ERK
214
ERK1
210
MAPK
206
ATP
195
p38
172
E-cadherin
172
p53
168
threonine
163
TNF
162
TTK
155
glycogen synthase
150
cytokine
144
amyloid precursor protein
143
serine/threonine kinase
141
phosphatase
141
GSK3
132
JNK
132
PKB
124
IRS-1
121
PTEN
120
Axin
112
brain-derived neurotrophic factor
106
axonal
104
more...
Disease
cancer
1004
Alzheimer's disease
961
tumor
643
diabetes
324
ischemia
245
tumorigenesis
199
breast cancer
170
hepatocellular carcinoma
145
cognitive impairment
135
Parkinson's disease
128
carcinogenesis
126
bipolar disorder
123
neuroblastoma
122
tumor growth
121
depression
118
type 2 diabetes
117
colorectal cancer
109
colon cancer
100
dementia
96
schizophrenia
95
stroke
94
carcinoma
93
prostate cancer
88
tumor progression
85
obesity
72
GSH
67
lung cancer
65
cerebral ischemia
63
MCF
61
leukemia
60
glioma
59
melanoma
56
myocardial infarction
56
APC
55
adenocarcinoma
55
gastric cancer
54
memory impairment
52
pancreatic cancer
52
hyperglycemia
48
heart failure
47
more...
Symptom
pain
36
functional recovery
29
seizures
24
memory loss
19
anesthesia
15
starvation
15
collapse
14
diarrhea
7
acute stress
7
hypothermia
7
fatigue
6
respiratory distress
4
nausea
4
despair
4
cachexia
4
ataxia
4
agitation
4
tremor
3
polyuria
3
exhaustion
2
bradykinesia
2
insomnia
2
abdominal pain
2
neurological disability
2
Scratch
2
weakness
2
sleepiness
2
skin damage
2
vomiting
2
hyperoxia
2
apathy
2
incoordination
2
chorea
2
wheezing
1
decreased appetite
1
hypotonia
1
acute pain
1
muscle rigidity
1
adenitis
1
anorexia
1
more...
Drug
ROS
64
lysine
51
MAP
33
Cardiovasc
19
Monit
15
Dermatol
13
IL-2
13
Sorafenib
11
Ethanol
10
ICI
9
CSF
9
Bortezomib
9
caffeine
8
Ezetimibe
8
CTX
8
Donepezil
7
Everolimus
7
Gel
6
Lenalidomide
6
CIA
6
Glycyrrhiza
6
Pegasys
6
Pemetrexed disodium
6
Taxol
6
Gefitinib
6
Denosumab
6
Dasatinib
6
Gleevec
6
PCP
6
Sunitinib malate
6
Portal
6
vitamin E
6
CTX
6
Tocilizumab
6
Vorinostat
6
NVP
6
CTX
6
EE2
6
Bevacizumab
6
Peginterferon alfa-2b
5
more...
Enzyme
GSK
6788
protein kinase
1908
mitogen-activated protein kinase
642
caspase-3
305
ERK
304
phosphatidylinositol 3-kinase
256
focal adhesion kinase
247
protein kinase C
208
calcineurin
169
MEK
138
cdc2
100
superoxide dismutase
98
luciferase
97
phosphoinositide 3-kinase
95
proteasome
94
AMP-activated protein kinase
91
AMPK
81
caspase-9
63
PARP
62
protein phosphatase 2A
57
APC
55
AMPK
53
lactate dehydrogenase
52
catalase
49
demethylase
45
alkaline phosphatase
44
acetylcholinesterase
44
ACS
38
PDK1
37
glutathione peroxidase
30
alanine aminotransferase
29
CaMKII
28
creatine kinase
28
MAP
28
phosphodiesterase
27
IKK
26
tyrosine hydroxylase
25
ATPase
25
caspase-8
24
aspartate aminotransferase
24
more...
Compound
glucose
489
Glycogen synthase
478
Dec
443
serine
364
DNA
309
threonine
299
oxygen
285
tyrosine
259
ATP
195
water
186
calcium
175
TNF
162
Lithium
138
cAMP
122
Insulin
105
glutamate
98
sodium
97
phosphate
95
Clin
94
MTT
93
MEK
90
MDA
77
GSH
67
nitric oxide
67
GSH
67
alanine
66
lysine
65
hydrogen
64
Glycogen
63
AMP
53
zinc
47
sulfate
46
Cardiol
45
ethanol
44
proline
40
bromide
39
retinoic acid
38
ACS
38
ACS
38
arginine
37
more...