Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.25 (MEKK1)
 1,856 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MLTK 14.1
mitogen-activated protein kinase kinase kinase 14.1
cellular modulator of immune recognition (c-MIR) 14.1
MRPL42 14.1
phosphodiesterase 3B, cGMP-inhibited 14.1
MEKK 14.1
MEKK3 14.0
MEKK2 13.9
MEKK1 13.5
tripartite motif-containing 48 13.1
UEV-3 13.1
TGF-beta activated kinase 1 13.1
MEKK4 13.0
MAP3K15 12.7
MEK kinase 2 12.5
Cerebral cavernous malformation 2 12.5
MUK-binding inhibitory protein 12.5
TAO2 12.4
MAP kinase kinase 4 12.2
MINK 12.2
Mixed lineage kinase 12.1
ZAK 12.1
MEK kinase 4 12.1
ZPK 12.1
TGF-beta activated kinase 12.1
TPL2 12.1
B-3501 12.1
suppressor of cytokine signaling 7 12.1
proline-rich transcript in brain 12.1
MKK5 11.9
MAP4K5 11.9
mixed lineage kinase 3 11.9
TAK1-binding protein 1 11.8
AIR1 11.7
CCDC14 11.7
MDS2 11.7
ASK2 11.7
MLK 11.7
MAP3K2 11.6
Nck-interacting kinase 11.6
more...
Disease
SPH1 10.3
CCM2 9.5
CCM3 8.6
Eosinophilic meningitis 8.6
Reovirus infection 8.6
Persistent hyperinsulinemic hypoglycemia of infancy 8.4
Bladder outlet obstruction 7.9
Brachydactyly 7.8
PARK8 7.8
cardiofaciocutaneous syndrome 7.7
amphetamine abuse 7.0
JIP 6.8
salivary gland cancer 6.8
Aeromonas hydrophila infection 6.7
EDS1 6.7
OCM 6.6
Simpson-Golabi-Behmel syndrome 6.2
ACS1 5.9
CEP 5.9
leukoderma 5.7
chondrodysplasia 5.6
pachygyria 5.6
Wolfram syndrome 5.5
renal clear cell carcinoma 5.4
Buerger's disease 5.3
familial dysautonomia 5.3
RGS 5.2
MEN 2B 5.2
benign nevi 5.2
olivopontocerebellar atrophy 5.1
SM1 5.1
plant disease 5.0
DVD 5.0
Chronic heart failure 5.0
DVD 5.0
juvenile myelomonocytic leukemia 5.0
Optic nerve 4.9
FBS 4.9
kidney tumor 4.8
Ovarian Cancer 4.7
more...
Symptom
motor symptom 5.2
starvation 3.0
acute stress 2.9
bradykinesia 2.9
hyperoxia 2.7
HSA 2.5
memory loss 2.2
splenomegaly 1.8
lethargy 1.6
hypotonia 1.6
tremor 0.9
anorexia 0.3
collapse 0.3
ataxia 0.1
seizures 0.1
dyspnea -0.7
anesthesia -2.7
pain -2.9
Drug
Oxendolone 10.7
Ciglitazone 7.8
Batimastat 7.5
Batimastat 7.5
CMZ 7.5
Nexavar 7.3
Morphine sulfate 7.2
Magnesium sulfate 7.1
TAK 6.7
NOV 6.3
Tarceva 6.3
MAP 6.2
EDR 5.7
K-252a 5.6
Rosuvastatin 5.2
Emodin 5.2
CED 4.9
Emodin 4.9
uPA 4.6
Erlotinib 4.5
p75 4.5
Activin 4.3
ETS 4.3
Aprotinin 4.2
Luteinizing 4.0
AraC 4.0
IL-11 3.9
Capsicum 3.9
Gefitinib 3.8
RFP 3.8
CoCl2 3.8
CoCl2 3.8
Angiotensin II 3.8
Arsenic trioxide 3.7
Fentanyl 3.7
Nitric Oxide 3.7
IFN-beta 3.5
Sorafenib 3.5
BH4 3.5
MgSO4 3.5
more...
Enzyme
MEKK1 14.1
NSY 11.0
MEK 9.1
IKK 8.1
CLK1 8.1
retinyl ester hydrolase 7.7
mitogen-activated protein kinase 7.7
stilbene synthase 7.3
ceramide kinase 7.3
MAP 7.3
stilbene synthase 7.2
isochorismate synthase 6.9
UDP-glucosyltransferase 6.8
lecithin:retinol acyltransferase 6.7
PHD 6.6
phosphatidylserine synthase 6.5
PIP kinase 6.4
alpha-sarcin 6.3
CEP 6.1
protein kinase 6.0
GRK2 5.9
6-phosphofructo-2-kinase 5.7
caspase-11 5.6
caspase-11 5.6
CEP 5.5
histidine kinase 5.4
xylose isomerase 5.4
caspase-2 5.4
ERK 5.3
p100 5.3
phosphoinositide 3-kinase 5.2
kinesin 5.2
GAS 5.2
protein kinase C 5.1
CaMKII 5.1
protein phosphatase 2A 5.1
phosphoribulokinase 5.0
isopeptidase 4.9
calcineurin 4.8
GTP cyclohydrolase I 4.7
more...
Compound
5-chloro-2-hydroxybenzamide 10.6
Farrerol 9.5
ASK 9.3
HOG 8.7
KT-1 8.6
9AA 8.2
9AA 8.2
MEK 8.0
Deguelin 7.8
Diallyl sulfide 7.7
ACES 7.7
Benzyl isothiocyanate 7.5
Anisomycin 7.5
Morphine sulfate 7.4
Paricalcitol 7.3
Serpentine 7.2
Phenethyl isothiocyanate 7.2
Juglone 7.2
dUDP 7.2
TRU 7.0
Magnesium sulfate 6.9
MAP 6.9
Biochanin A 6.9
Magnesium sulfate 6.8
Bufalin 6.8
ATF 6.7
KIV 6.6
CUE 6.6
Ginsenoside Rg1 6.5
Parthenolide 6.4
MAK 6.4
GF 109203X 6.3
Chelerythrine 6.2
Chelerythrine 6.2
Parthenolide 6.2
(-)-Epigallocatechin 6.2
Fisetin 6.1
Anthocyanin 6.0
Formin 6.0
DETA 6.0
more...