Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.25 (MEKK1)
 1,856 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MEKK 0.567
MEKK1 0.165
mitogen-activated protein kinase kinase kinase 0.153
MEKK3 0.073
MEKK2 0.046
MEKK4 0.010
MKK4 0.010
apoptosis signal-regulating kinase 1 0.007
TAK1 0.006
MEK 0.005
MKK7 0.005
ASK1 0.004
MLTK 0.004
JNK 0.004
MKK3 0.003
MEK5 0.003
MAPK 0.003
MAP kinase 0.003
mixed lineage kinase 3 0.003
TPL2 0.003
MKK6 0.002
MLK 0.002
TPL-2 0.002
p38 0.002
TGF-beta activated kinase 1 0.002
ZAK 0.002
NS5 0.002
c-Jun 0.002
MAP2K1 0.002
ERK5 0.002
MKK5 0.002
JNK1 0.001
MAP kinase kinase 4 0.001
Mixed lineage kinase 0.001
TAB1 0.001
TAO2 0.001
mitogen-activated protein 0.001
MEK2 0.001
MEK1 0.001
TAK1-binding protein 1 0.001
MAP3K5 0.001
ASK2 0.001
SEK 0.001
DLK 0.001
MEK kinase 2 0.001
Nck-interacting kinase 0.001
MLK3 0.001
IkappaB kinase 0.001
ZPK 0.001
MAP3K2 0.001
NIK 0.001
MyD118 0.001
ERK 0.001
MRPL42 0.001
cellular modulator of immune recognition (c-MIR) 0.001
phosphodiesterase 3B, cGMP-inhibited 0.001
MAP3K15 0.001
MINK 0.001
transforming growth factor-beta-activated kinase 1 0.001
TAB2 0.001
TGF-beta-activated kinase 1 0.001
MAP3K3 0.001
TRAF2 0.001
ERK2 0.001
tripartite motif-containing 48 0.001
UEV-3 0.001
Raf-1 0.001
LZK 0.001
MAP3K8 0.001
extracellular signal-regulated kinase 0.001
ERK1 0.000
MAP3 0.000
MAPK/ERK kinase 0.000
JNK2 0.000
mixed lineage kinase 0.000
MAP4K5 0.000
IKK 0.000
HPK1 0.000
MUK-binding inhibitory protein 0.000
Cerebral cavernous malformation 2 0.000
ICAP-1 0.000
MLK2 0.000
AP-1 0.000
EDR1 0.000
mitogen-activated protein kinase kinase kinase 3 0.000
MAP3K7 0.000
TGF-beta activated kinase 0.000
MEK kinase 4 0.000
MAP4K1 0.000
suppressor of cytokine signaling 7 0.000
proline-rich transcript in brain 0.000
B-3501 0.000
extracellular signal-regulated kinase 5 0.000
MAP 0.000
p38b 0.000
p38delta 0.000
STE20 0.000
PG2 0.000
TRAF6 0.000
MAP3K9 0.000
p38 MAP kinase 0.000
MDS2 0.000
CCDC14 0.000
ECSIT 0.000
AIR1 0.000
JIP1 0.000
TAK1-binding protein 2 0.000
PSK1 0.000
Glycinamide ribonucleotide formyltransferase 0.000
MAPKBP1 0.000
MAD protein 0.000
COP9 signalosome subunit 6 0.000
Cardiotrophin 1 0.000
TNF receptor-associated factor 4 0.000
RalGDS-like factor 0.000
KRIT1 0.000
ASK 0.000
PPEF-2 0.000
MYLK3 0.000
SSR3 0.000
CCM2 0.000
TAB3 0.000
MAP2K3 0.000
STX5 0.000
germinal center kinase-like kinase 0.000
GLK 0.000
ATF2 0.000
p38 mitogen-activated protein kinase 0.000
MAPKK6 0.000
CENTG1 0.000
retinitis pigmentosa GTPase regulator interacting protein 1 0.000
kinase suppressor of ras 0.000
HSF2BP 0.000
Protocadherin-8 0.000
SPRK 0.000
MAP3K4 0.000
Mak3p 0.000
HGK 0.000
MAP3K12 0.000
TNF receptor-associated factor 2 0.000
threonine 0.000
hematopoietic progenitor kinase 1 0.000
p105 0.000
MAPK4 0.000
Histone deacetylase 7 0.000
GRASP-1 0.000
SPAS-1 0.000
Fetuin-B 0.000
JUN N-terminal kinase 0.000
MAP4K3 0.000
MAP4K2 0.000
VIK 0.000
FBXW5 0.000
JNK3 0.000
B-Raf protein 0.000
COT 0.000
JSAP1 0.000
Rho-associated, coiled-coil containing protein kinase 1 0.000
TANC1 0.000
LYK5 0.000
more...
Disease
CCM2 0.000
SPH1 0.000
CCM3 0.000
Eosinophilic meningitis 0.000
Reovirus infection 0.000
Persistent hyperinsulinemic hypoglycemia of infancy 0.000
Bladder outlet obstruction 0.000
PARK8 0.000
Brachydactyly 0.000
cardiofaciocutaneous syndrome 0.000
cancer 0.000
JIP 0.000
amphetamine abuse 0.000
salivary gland cancer 0.000
Aeromonas hydrophila infection 0.000
tumorigenesis 0.000
EDS1 0.000
OCM 0.000
CEP 0.000
Simpson-Golabi-Behmel syndrome 0.000
chondrodysplasia 0.000
tumor 0.000
ACS1 0.000
leukoderma 0.000
pachygyria 0.000
metastatic melanoma 0.000
Buerger's disease 0.000
Wolfram syndrome 0.000
plant disease 0.000
RGS 0.000
renal clear cell carcinoma 0.000
familial dysautonomia 0.000
melanoma 0.000
FBS 0.000
MEN 2B 0.000
benign nevi 0.000
Parkinson's disease 0.000
olivopontocerebellar atrophy 0.000
SM1 0.000
DVD 0.000
embryonal carcinoma 0.000
Chronic heart failure 0.000
DVD 0.000
juvenile myelomonocytic leukemia 0.000
Osteosarcoma 0.000
Osteosarcoma 0.000
breast cancer 0.000
AGS 0.000
MIP 0.000
Optic nerve 0.000
kidney tumor 0.000
infectious endocarditis 0.000
tumor progression 0.000
ATM 0.000
Ovarian Cancer 0.000
tumor growth 0.000
Angiostrongylus cantonensis 0.000
pituitary tumor 0.000
osteopetrosis 0.000
Dementia with Lewy bodies 0.000
Apert syndrome 0.000
Blocking 0.000
neurofibromatosis 0.000
Still's disease 0.000
neuroblastoma 0.000
pertussis 0.000
neoplastic transformation 0.000
dysplastic nevi 0.000
CLN3 0.000
ischemia 0.000
Bardet-Biedl syndrome 0.000
Tumour necrosis 0.000
tumor initiation 0.000
malignant ascites 0.000
hyperosmolality 0.000
MEC 0.000
cold 0.000
ovarian cancer 0.000
leukemia 0.000
myelofibrosis 0.000
adenocarcinoma of the pancreas 0.000
carcinogenesis 0.000
Testis 0.000
Testis 0.000
Menkes 0.000
cerebral ischemia 0.000
LDLR 0.000
renal ischemia 0.000
HOS 0.000
NF2 0.000
SMC 0.000
hypercalcemia 0.000
HGF 0.000
PPP 0.000
bacterial infection 0.000
renal cancer 0.000
gonadal dysgenesis 0.000
Beckwith-Wiedemann syndrome 0.000
virus infection 0.000
Esophageal squamous cell carcinoma 0.000
osteosarcoma 0.000
worms 0.000
chemical carcinogenesis 0.000
Ischemic stroke 0.000
oral cancer 0.000
Adenovirus 0.000
acute nonlymphocytic leukemia 0.000
Fox 0.000
plasmacytoma 0.000
progressive supranuclear palsy 0.000
conductive hearing loss 0.000
atherosclerosis 0.000
APC 0.000
AAS 0.000
prostate cancer 0.000
cutaneous melanoma 0.000
immune deficiency 0.000
NOD 0.000
colibacillosis 0.000
endometrial adenocarcinoma 0.000
adrenocortical carcinoma 0.000
Alzheimer's disease 0.000
rheumatoid arthritis 0.000
MCF 0.000
myeloid leukemia 0.000
erythroleukemia 0.000
colon cancer 0.000
Kawasaki disease 0.000
fibrosarcoma 0.000
dehydration 0.000
neuritis 0.000
lung cancer 0.000
TAM 0.000
heart failure 0.000
glioblastoma 0.000
ABL 0.000
liver fibrosis 0.000
medulloblastoma 0.000
metastases 0.000
MLC 0.000
IVA 0.000
squamous cell carcinoma 0.000
myeloproliferative disorders 0.000
optic atrophy 0.000
pancreatic cancer 0.000
pheochromocytoma 0.000
drug withdrawal 0.000
glomerulopathy 0.000
lymphoma 0.000
HTLV-I 0.000
non-small cell lung cancer 0.000
telangiectasia 0.000
hairy cell leukemia 0.000
Epstein 0.000
HAM 0.000
psychological stress 0.000
retinoblastoma 0.000
degenerative disease 0.000
EMT 0.000
listeriosis 0.000
more...
Symptom
motor symptom 0.000
starvation 0.000
acute stress 0.000
hyperoxia 0.000
bradykinesia 0.000
HSA 0.000
memory loss 0.000
splenomegaly 0.000
lethargy 0.000
hypotonia 0.000
tremor 0.000
seizures 0.000
collapse 0.000
anorexia 0.000
ataxia 0.000
dyspnea 0.000
anesthesia 0.000
pain 0.000
Drug
Oxendolone 0.000
MAP 0.000
Ciglitazone 0.000
TAK 0.000
Batimastat 0.000
Batimastat 0.000
CMZ 0.000
Nexavar 0.000
Magnesium sulfate 0.000
Morphine sulfate 0.000
NOV 0.000
Tarceva 0.000
EDR 0.000
K-252a 0.000
p75 0.000
lysine 0.000
Rosuvastatin 0.000
Emodin 0.000
uPA 0.000
ROS 0.000
CED 0.000
Emodin 0.000
ETS 0.000
Erlotinib 0.000
Activin 0.000
Angiotensin II 0.000
Aprotinin 0.000
Gel 0.000
Capsicum 0.000
Luteinizing 0.000
AraC 0.000
IL-11 0.000
Nitric Oxide 0.000
Gefitinib 0.000
RFP 0.000
CoCl2 0.000
CoCl2 0.000
Arsenic trioxide 0.000
Fentanyl 0.000
IFN-beta 0.000
Sorafenib 0.000
BH4 0.000
MgSO4 0.000
TAC 0.000
Parkin 0.000
Parkin 0.000
Estrogens 0.000
caffeine 0.000
TAT 0.000
Fluorescein 0.000
Alanine 0.000
Indomethacin 0.000
Asn 0.000
Vitamin A 0.000
Taxol 0.000
MRC 0.000
CSF 0.000
Fluorescein 0.000
IFN-gamma 0.000
Adriamycin 0.000
FAD 0.000
CaCl2 0.000
CaCl2 0.000
CaCl2 0.000
IL-2 0.000
DNase I 0.000
nitroglycerin 0.000
Ethanol 0.000
citric acid 0.000
CTX 0.000
lactose 0.000
vitamin E 0.000
Leaf 0.000
NADH 0.000
ascorbate 0.000
Dial 0.000
Dermatol 0.000
Cardiovasc 0.000
Enzyme
MEKK1 0.999
MEK 0.010
mitogen-activated protein kinase 0.007
IKK 0.001
protein kinase 0.001
NSY 0.001
MAP 0.000
ERK 0.000
protein kinase C 0.000
CLK1 0.000
luciferase 0.000
retinyl ester hydrolase 0.000
calcineurin 0.000
stilbene synthase 0.000
PHD 0.000
stilbene synthase 0.000
caspase-3 0.000
ceramide kinase 0.000
phosphoinositide 3-kinase 0.000
kinesin 0.000
isochorismate synthase 0.000
phosphatidylinositol 3-kinase 0.000
UDP-glucosyltransferase 0.000
focal adhesion kinase 0.000
lecithin:retinol acyltransferase 0.000
proteasome 0.000
CEP 0.000
phosphatidylserine synthase 0.000
histidine kinase 0.000
CaMKII 0.000
PIP kinase 0.000
GRK2 0.000
alpha-sarcin 0.000
glutathione S-transferase 0.000
protein phosphatase 2A 0.000
CEP 0.000
urokinase-type plasminogen activator 0.000
6-phosphofructo-2-kinase 0.000
caspase-11 0.000
caspase-11 0.000
caspase-2 0.000
caspase-9 0.000
NADPH oxidase 0.000
p100 0.000
xylose isomerase 0.000
AMPK 0.000
cdc2 0.000
NADPH oxidase 0.000
GAS 0.000
myosin light chain kinase 0.000
collagenase 0.000
thrombin 0.000
phosphoribulokinase 0.000
MIP 0.000
GSK 0.000
isopeptidase 0.000
phospholipase C 0.000
PGM 0.000
GTP cyclohydrolase I 0.000
triphosphatase 0.000
polo-like kinase 1 0.000
caspase-8 0.000
caspase-2 0.000
transglutaminase 0.000
peptidyl-prolyl cis-trans isomerase 0.000
TMT 0.000
CPT 0.000
AMP-activated protein kinase 0.000
MPP 0.000
PARP 0.000
CPT 0.000
DCF 0.000
beta-secretase 0.000
caspase-7 0.000
caspase-7 0.000
chaperonin 0.000
CYP7A1 0.000
PDK1 0.000
AMPK 0.000
PTPase 0.000
ADP-ribosyltransferase 0.000
matrix metalloproteinase 2 0.000
ADP-ribosyltransferase 0.000
PKG 0.000
GRK5 0.000
CPT 0.000
peroxiredoxin 0.000
uricase 0.000
xanthine dehydrogenase 0.000
cellulose synthase 0.000
chloramphenicol acetyltransferase 0.000
LPL 0.000
Mg2+-ATPase 0.000
NO synthase 0.000
ATPase 0.000
prolyl hydroxylase 0.000
prostaglandin synthetase 0.000
heme oxygenase 0.000
cathepsin L 0.000
NADH dehydrogenase 0.000
complex I 0.000
TAT 0.000
thioredoxin reductase 0.000
MDP 0.000
catalase 0.000
ribonucleotide reductase 0.000
glucokinase 0.000
superoxide dismutase 0.000
ribonucleotide reductase 0.000
ricin 0.000
NOS 0.000
thymidine kinase 0.000
MMP-3 0.000
thymidylate synthase 0.000
nitrate reductase 0.000
nitrate reductase 0.000
nitrate reductase 0.000
nitrate reductase 0.000
nitrate reductase 0.000
phospholipase D 0.000
guanylate cyclase 0.000
nitrate reductase 0.000
topoisomerase 0.000
APC 0.000
cathepsin B 0.000
MMP 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
topoisomerase 0.000
hyaluronidase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
invertase 0.000
DNA methyltransferase 0.000
tissue plasminogen activator 0.000
pyruvate kinase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
diaphorase 0.000
NQO1 0.000
hyaluronidase 0.000
caspase-1 0.000
ornithine decarboxylase 0.000
phospholipase A2 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
tyrosine hydroxylase 0.000
lactate dehydrogenase 0.000
succinate dehydrogenase 0.000
xanthine oxidase 0.000
adenylate cyclase 0.000
lipoxygenase 0.000
RNA polymerase 0.000
transcriptase 0.000
glutathione reductase 0.000
peroxidase 0.000
P-glycoprotein 0.000
beta-lactamase 0.000
reverse transcriptase 0.000
neuraminidase 0.000
phosphodiesterase 0.000
ACS 0.000
aspartate aminotransferase 0.000
more...
Compound
MEK 0.001
MAP 0.000
threonine 0.000
ASK 0.000
HOG 0.000
5-chloro-2-hydroxybenzamide 0.000
serine 0.000
Farrerol 0.000
KT-1 0.000
ATF 0.000
tyrosine 0.000
9AA 0.000
9AA 0.000
Deguelin 0.000
GTP 0.000
ACES 0.000
Diallyl sulfide 0.000
TNF 0.000
Anisomycin 0.000
Benzyl isothiocyanate 0.000
Morphine sulfate 0.000
Paricalcitol 0.000
NH2 0.000
COS 0.000
Serpentine 0.000
Phenethyl isothiocyanate 0.000
Juglone 0.000
dUDP 0.000
Magnesium sulfate 0.000
TRU 0.000
Magnesium sulfate 0.000
Biochanin A 0.000
ABA 0.000
Bufalin 0.000
MAK 0.000
salicylic acid 0.000
KIV 0.000
DNA 0.000
CUE 0.000
Ginsenoside Rg1 0.000
PMA 0.000
GF 109203X 0.000
Parthenolide 0.000
acetate 0.000
Chelerythrine 0.000
Chelerythrine 0.000
Parthenolide 0.000
Anthocyanin 0.000
DETA 0.000
(-)-Epigallocatechin 0.000
Thioredoxin 0.000
cAMP 0.000
leucine 0.000
Fisetin 0.000
Curcumin 0.000
Formin 0.000
D-Serine 0.000
LY 294002 0.000
PMA 0.000
Phorbol 12-myristate 13-acetate 0.000
TPA 0.000
2-phosphoglycerate 0.000
oxygen 0.000
PGA1 0.000
alanine 0.000
Sulindac 0.000
Apigenin 0.000
glycerol 0.000
adenosylmethionine 0.000
TPA 0.000
Tetrahydrobiopterin 0.000
ABA 0.000
25-dihydroxycholecalciferol 0.000
Serine 0.000
CHIP 0.000
ATP 0.000
PAM 0.000
calcium 0.000
lysine 0.000
Dec 0.000
Fumarate 0.000
SP-1 0.000
Cbl 0.000
Fucoidan 0.000
H2O2 0.000
Emodin 0.000
Cys-Gly 0.000
Emodin 0.000
G11 0.000
Endosulfan 0.000
Neutral Red 0.000
Tanshinone 0.000
Cer 0.000
Wortmannin 0.000
Arsenate 0.000
SCC 0.000
BHC 0.000
AF-2 0.000
Ang II 0.000
APH 0.000
AMP 0.000
Leucine 0.000
Ethylene 0.000
Arsenite 0.000
Vinblastine 0.000
salt 0.000
THP 0.000
PYR 0.000
proline 0.000
THP 0.000
Phosphatidylinositol 0.000
HPT 0.000
Rhodopsin 0.000
Actinomycin D 0.000
PGE 0.000
Tiron 0.000
DEP 0.000
MPP 0.000
Uridine 0.000
CPT 0.000
MPP 0.000
1H-imidazole 0.000
MDA 0.000
Pioglitazone 0.000
SAH 0.000
quinazoline 0.000
quinazoline 0.000
AEA 0.000
MAD 0.000
cGMP 0.000
Okadaic acid 0.000
CPT 0.000
AAT 0.000
Tumor Necrosis Factor 0.000
N-acetylcysteine 0.000
Tamoxifen 0.000
GDP 0.000
Tamoxifen 0.000
cysteine 0.000
DPI 0.000
NEM 0.000
DEP 0.000
CAT 0.000
CAT 0.000
AGE 0.000
Ochratoxin A 0.000
ASC 0.000
hydrogen 0.000
CAT 0.000
SPD 0.000
nitric oxide 0.000
Resveratrol 0.000
Staurosporine 0.000
PAR 0.000
Staurosporine 0.000
Glycogen synthase 0.000
naphthoquinone 0.000
naphthoquinone 0.000
naphthoquinone 0.000
naphthoquinone 0.000
more...