EC:2.7.11.24 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: EC:2.7.11.24 (mitogen-activated protein kinase)
95,810 document(s) hit in 31,850,051 MEDLINE articles (0.07 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
MAPK	0.310
ERK1	0.227
p38	0.182
JNK	0.171
extracellular signal-regulated kinase	0.126
MAP kinase	0.092
ERK	0.069
mitogen-activated protein	0.040
MEK	0.039
ERK2	0.029
p38 mitogen-activated protein kinase	0.029
MEK1	0.023
c-Jun	0.023
p42	0.017
p44	0.016
extracellular signal-regulated kinase 1	0.014
JNK1	0.013
PI3K	0.012
AKT	0.011
P38	0.007
phosphatidylinositol 3-kinase	0.006
AP-1	0.006
p38 MAP kinase	0.005
MAP	0.005
MKK4	0.005
p38MAPK	0.005
MEKK	0.005
caspase-3	0.004
BRAF	0.004
Raf-1	0.004
JNK2	0.004
protein kinase B	0.004
MKK3	0.003
p65	0.003
MKP-1	0.003
PKC	0.003
TNF	0.003
RAF	0.003
mTOR	0.003
MKK6	0.003
Bcl-2	0.003
MKK7	0.003
cytokine	0.003
ERK5	0.002
IL-6	0.002
MAPK/ERK kinase	0.002
tyrosine kinase	0.002
MEKK1	0.002
ASK1	0.002
MEK2	0.002
phosphatase	0.002
phosphoinositide 3-kinase	0.002
PI3	0.002
extracellular signal regulated kinase	0.002
STAT	0.002
tumor necrosis factor	0.002
Mol	0.002
inducible nitric oxide synthase	0.002
STAT3	0.002
epidermal growth factor receptor	0.002
cyclooxygenase-2	0.002
lipopolysaccharide	0.002
epidermal growth factor	0.002
CREB	0.002
TLR4	0.002
ribosomal S6 kinase	0.002
apoptosis signal-regulating kinase 1	0.002
MAP2K1	0.002
cyclin D1	0.001
EGFR	0.001
focal adhesion kinase	0.001
EGF	0.001
IRS-1	0.001
IL-8	0.001
p21	0.001
p90	0.001
PKA	0.001
JUN N-terminal kinase	0.001
p53	0.001
MKP-3	0.001

Disease
cancer	0.002
tumor	0.002
tumorigenesis	0.001
tumor growth	0.001
breast cancer	0.001
melanoma	0.001
pertussis	0.001
MCF	0.001
tumor progression	0.000
hepatocellular carcinoma	0.000
carcinogenesis	0.000
Blocking	0.000
ischemia	0.000
neuroblastoma	0.000
Costello syndrome	0.000
colon cancer	0.000
atherosclerosis	0.000
glioma	0.000
lung cancer	0.000
Alzheimer's disease	0.000
cardiofaciocutaneous syndrome	0.000
colorectal cancer	0.000
prostate cancer	0.000
glioblastoma	0.000
carcinoma	0.000
leukemia	0.000
ATM	0.000
non-small cell lung cancer	0.000
GSH	0.000
pancreatic cancer	0.000
AGS	0.000
adenocarcinoma	0.000
ovarian cancer	0.000
obesity	0.000
metastatic melanoma	0.000
gastric cancer	0.000
diabetes	0.000
retinoblastoma	0.000
cerebral ischemia	0.000
Melanoma	0.000
tumor angiogenesis	0.000
HGF	0.000
squamous cell carcinoma	0.000
Parkinson's disease	0.000
B-cell lymphoma	0.000
MIP	0.000
diabetic nephropathy	0.000
rheumatoid arthritis	0.000
liver cancer	0.000
osteosarcoma	0.000
type 2 diabetes	0.000
JIP	0.000
hyperglycemia	0.000
acute myeloid leukemia	0.000
pheochromocytoma	0.000
thyroid cancer	0.000
liver fibrosis	0.000
LEOPARD syndrome	0.000
liver cancer	0.000
osteoporosis	0.000
colitis	0.000
asthma	0.000
multiple myeloma	0.000
astrocytoma	0.000
hypertension	0.000
Hepatocellular carcinoma	0.000
sepsis	0.000
skin cancer	0.000
sepsis	0.000
chronic myeloid leukemia	0.000
papillary thyroid cancer	0.000
EMT	0.000
metastases	0.000
myeloid leukemia	0.000
lung carcinoma	0.000
tumor initiation	0.000
osteoarthritis	0.000
Osteosarcoma	0.000
Osteosarcoma	0.000
anaplastic thyroid cancer	0.000

Symptom
starvation	0.000
pain	0.000
skin damage	0.000
Inflammatory pain	0.000
functional recovery	0.000
Neuropathic pain	0.000
hyperoxia	0.000
Scratch	0.000
impaired body balance	0.000
seizures	0.000
collapse	0.000
Thalamic pain	0.000
memory loss	0.000
acute stress	0.000
Incisional pain	0.000
cachexia	0.000
respiratory distress	0.000
diarrhea	0.000
Ear swelling	0.000
SYMPTOMS	0.000
hypothermia	0.000
analgesia	0.000
Mucosal hyperplasia	0.000
bone pain	0.000
Bladder distention	0.000
cardiovascular problem	0.000
despair	0.000
Organ failure	0.000
Central post-stroke pain	0.000
exhaustion	0.000
splenomegaly	0.000
Mechanical pain	0.000
orofacial pain	0.000
arthralgia	0.000
scaly skin	0.000
bladder pain	0.000
dry eye	0.000
impaired motor coordination	0.000
stomach cramps	0.000
erythema	0.000
fatigue	0.000
Macula	0.000
female puberty	0.000
HSA	0.000
ataxia	0.000
dry skin	0.000
GI irritation	0.000
anesthesia	0.000
thinning	0.000
pelvic pain	0.000
neurological disability	0.000
low back pain	0.000
Behavioral symptoms	0.000
Motor dysfunction	0.000
delayed language development	0.000
Anoxia	0.000
Noise-induced hearing loss	0.000
muscle cramps	0.000
hypotonia	0.000
ACHE	0.000
fasciculation	0.000
cough	0.000
headache	0.000
Visceral pain	0.000
cancer pain	0.000
weakness	0.000
overweight	0.000
decreased appetite	0.000
menopausal symptoms	0.000
incoordination	0.000
anorexia	0.000
acute pain	0.000
nausea	0.000
microbial colonization	0.000
skin irritation	0.000
hepatosplenomegaly	0.000
hypercapnia	0.000
skin irritant	0.000
hepatomegaly	0.000
bradykinesia	0.000

Drug
MAP	0.003
ROS	0.001
Angiotensin II	0.000
ICI	0.000
Sorafenib	0.000
Gefitinib	0.000
ETS	0.000
IL-2	0.000
Arsenic trioxide	0.000
p75	0.000
IFN-gamma	0.000
TAK	0.000
CSF	0.000
Epigallocatechin	0.000
NVP	0.000
uPA	0.000
Forskolin	0.000
Heme	0.000
Cetuximab	0.000
IL-11	0.000
Emodin	0.000
Rosiglitazone	0.000
Ciglitazone	0.000
Activin	0.000
lysine	0.000
Simvastatin	0.000
CCL	0.000
Erlotinib	0.000
Taxol	0.000
Herceptin	0.000
Emodin	0.000
Imatinib	0.000
Xaliproden	0.000
GEO	0.000
IFN-beta	0.000
Doramapimod	0.000
Fulvestrant	0.000
Myricetin	0.000
K-252a	0.000
Estrogens	0.000
TAT	0.000
Dasatinib	0.000
Gelatin	0.000
ETA	0.000
RAL	0.000
Gleevec	0.000
S-Adenosyl-L-Homocysteine	0.000
Fexaramine	0.000
Caprylic Acid	0.000
Tarceva	0.000
Ethanol	0.000
Retinoic acid	0.000
Glycyrrhiza	0.000
ADR	0.000
Bortezomib	0.000
3-Methyladenine	0.000
2-Methoxyestradiol	0.000
PTC	0.000
EE2	0.000
Lovastatin	0.000
Nitric Oxide	0.000
Nexavar	0.000
Dermatol	0.000
Scutellaria root	0.000
PFT	0.000
Fingolimod hydrochloride	0.000
Vandetanib	0.000
Gypsum fibrosum	0.000
Aicar	0.000
Ouabain	0.000
Benfotiamine	0.000
GHRP	0.000
Olmesartan	0.000
Atractylodes lancea rhizome	0.000
vitamin E	0.000
Tipifarnib	0.000
Zanthoxylum fruit	0.000
Asiasarum root	0.000
Canertinib dihydrochloride	0.000
Olomoucine	0.000

Enzyme
mitogen-activated protein kinase	1.000
MEK	0.065
ERK	0.030
protein kinase	0.010
MEKK1	0.007
protein kinase C	0.007
phosphatidylinositol 3-kinase	0.006
MAP	0.005
caspase-3	0.003
focal adhesion kinase	0.002
phosphoinositide 3-kinase	0.002
IKK	0.001
NADPH oxidase	0.001
PARP	0.001
NADPH oxidase	0.001
AMP-activated protein kinase	0.001
caspase-9	0.001
calcineurin	0.001
luciferase	0.001
GSK	0.001
phospholipase C	0.001
caspase-8	0.001
AMPK	0.001
AMPK	0.001
cdc2	0.000
CaMKII	0.000
protein phosphatase 2A	0.000
proteasome	0.000
NO synthase	0.000
superoxide dismutase	0.000
collagenase	0.000
MMP	0.000
inositol 3-kinase	0.000
MMP-3	0.000
phospholipase A2	0.000
catalase	0.000
PDK1	0.000
cathepsin K	0.000
PKG	0.000
sphingosine kinase	0.000
urokinase-type plasminogen activator	0.000
GRK5	0.000
heme oxygenase	0.000
glutathione S-transferase	0.000
caspase-1	0.000
phospholipase D	0.000
MIP	0.000
GRK2	0.000
farnesyltransferase	0.000
thrombin	0.000
farnesyltransferase	0.000
caspase-7	0.000
alkaline phosphatase	0.000
caspase-7	0.000
myosin light chain kinase	0.000
lactate dehydrogenase	0.000
matrix metalloproteinase 9	0.000
PTPase	0.000
phosphatidylinositol-4,5-bisphosphate 3-kinase	0.000
adenylate cyclase	0.000
MPP	0.000
DCF	0.000
NOS	0.000
TOR	0.000
CEP	0.000
glutathione peroxidase	0.000
alanine aminotransferase	0.000
tyrosine hydroxylase	0.000
tyrosinase	0.000
CLK1	0.000
ATPase	0.000
aspartate aminotransferase	0.000
caspase-4	0.000
peroxidase	0.000
TACE	0.000
CEP	0.000
guanylate cyclase	0.000
caspase-4	0.000
histidine kinase	0.000
eEF2 kinase	0.000